Page last updated: 2024-10-24

chlorambucil and Necrobiotic Xanthogranuloma

chlorambucil has been researched along with Necrobiotic Xanthogranuloma in 2 studies

Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.

Necrobiotic Xanthogranuloma: A cutaneous necrobiotic disorder characterized by firm, yellow plaques or nodules, often in a periorbital distribution. It is often accompanied by an elevated ERYTHROCYTE SEDIMENTATION RATE; LEUKOPENIA; and MONOCLONAL GAMMOPATHY (IgG-kappa type) and systemic involvement.

Research Excerpts

ExcerptRelevanceReference
"This report of necrobiotic xanthogranuloma associated with chronic lymphocytic leukaemia describes the response of skin lesions to chlorambucil."7.78Necrobiotic xanthogranuloma: response to chlorambucil. ( Ryan, E; Szabo, F; Warren, LJ, 2012)
"Necrobiotic xanthogranuloma is a rare disease that is part of the non-Langerhans cell histiocytoses."3.01Therapy of necrobiotic xanthogranuloma - case series and review of the literature. ( Abeck, F; Booken, N; Ghandili, S; Hansen, I; Schneider, SW, 2023)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Hansen, I1
Ghandili, S1
Abeck, F1
Booken, N1
Schneider, SW1
Ryan, E1
Warren, LJ1
Szabo, F1

Reviews

1 review available for chlorambucil and Necrobiotic Xanthogranuloma

ArticleYear
Therapy of necrobiotic xanthogranuloma - case series and review of the literature.
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2023, Volume: 21, Issue:11

    Topics: Chlorambucil; Histiocytosis, Non-Langerhans-Cell; Humans; Necrobiotic Xanthogranuloma; Paraproteinem

2023

Other Studies

1 other study available for chlorambucil and Necrobiotic Xanthogranuloma

ArticleYear
Necrobiotic xanthogranuloma: response to chlorambucil.
    The Australasian journal of dermatology, 2012, Volume: 53, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Chlorambucil; Humans; Male; Middle Aged; Necrobiotic Xanthogranul

2012