Page last updated: 2024-10-24

chlorambucil and Mycosis Fungoides

chlorambucil has been researched along with Mycosis Fungoides in 17 studies

Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.

Mycosis Fungoides: A chronic, malignant T-cell lymphoma of the skin. In the late stages, the LYMPH NODES and viscera are affected.

Research Excerpts

ExcerptRelevanceReference
"Prednimustine, a chlorambucil ester of prednisolone, was administered orally to 5 patients with mycosis fungoides in advanced tumour stage."5.04Prednimustine in mycosis fungoides: a report from the Scandinavian mycosis fungoides study group. ( Bergqvist-Karlsson, A; Hellbe, L; Molin, L; Thomsen, K; Volden, G, 1979)
"Low-grade malignant lymphomas are treated best with conventional doses of an alkylating agent."1.26[Chemotherapy in non-Hodgkin's lymphomas (author's transl)]. ( Schmidt, CG, 1977)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199015 (88.24)18.7374
1990's0 (0.00)18.2507
2000's2 (11.76)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kamran, B1
Fatemeh, M1
Ahmadreza, R1
Azita, N1
FEIWEL, M1
MUNRO, DD1
WRIGHT, JC1
LYONS, MM1
WALKER, DG1
GOLOMB, FM1
GUMPORT, SL1
MEDREK, TJ1
ENGLE, I1
AAKHUS, T1
Geerts, ML1
Hamers, J1
Schwarze, EW1
Kint, A1
Roels, H1
Lennert, K1
Holmes, RC1
McGibbon, DH1
Black, MM1
Volk, AL1
Vannucci, SA1
Cook, W1
Thompson, KA1
Listinsky, CM1
Schmidt, CG1
Molin, L1
Thomsen, K1
Volden, G1
Bergqvist-Karlsson, A1
Hellbe, L1
Leavell, UW1
Mersack, IP1
Johnson, JL1
Butler, D1
Bernengo, MG1
Meregalli, M1
Jemma, C1
Lisa, F1
Shelley, WB1
Shelley, ED1
Mante, C1
Brodkin, RH1
Cohen, F1
Duperrat, B1
Escande, JP1
Pringuet, R1
Kaung, DT1
Wittington, RM1
Spencer, H1
Patno, ME1
Cohen, ML1
Weiss, EB1
Gueguen, MH1

Trials

2 trials available for chlorambucil and Mycosis Fungoides

ArticleYear
Prednimustine in mycosis fungoides: a report from the Scandinavian mycosis fungoides study group.
    Acta dermato-venereologica, 1979, Volume: 59, Issue:1

    Topics: Administration, Oral; Aged; Chlorambucil; Clinical Trials as Topic; Drug Combinations; Drug Evaluati

1979
Comparison of chlorambucil and streptonigrin (NSC-45383) in the treatment of malignant lymphomas.
    Cancer, 1969, Volume: 23, Issue:6

    Topics: Antibiotics, Antineoplastic; Bone Marrow; Chlorambucil; Clinical Trials as Topic; Digestive System;

1969

Other Studies

15 other studies available for chlorambucil and Mycosis Fungoides

ArticleYear
Bullous mycosis fungoides: a case report.
    Dermatology online journal, 2008, Feb-28, Volume: 14, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Fatal Outcome; Humans; Lichenoid

2008
THE RETICULOSES.
    The British journal of clinical practice, 1964, Volume: 18

    Topics: Adrenal Cortex Hormones; Chlorambucil; Cyclophosphamide; Dermatitis, Exfoliative; Genetic Diseases,

1964
OBSERVATIONS ON THE USE OF CANCER CHEMOTHERAPEUTIC AGENTS IN PATIENTS WITH MYCOSIS FUNGOIDES.
    Cancer, 1964, Volume: 17

    Topics: Alkylating Agents; Anti-Bacterial Agents; Antineoplastic Agents; Carbamates; Chlorambucil; Dactinomy

1964
INTESTINAL OBSTRUCTION IN MYCOSIS FUNGOIDES.
    The British journal of radiology, 1965, Volume: 38

    Topics: Chlorambucil; Drug Therapy; Humans; Intestinal Neoplasms; Intestinal Obstruction; Mycosis Fungoides;

1965
Mycosis fungoides and lymphoplasmacytoid immunocytoma in the same patient. A case report.
    Cancer, 1984, Nov-15, Volume: 54, Issue:10

    Topics: Chlorambucil; Cytoplasm; Female; Hematologic Tests; Humans; Immunoglobulin lambda-Chains; Immunoglob

1984
Mycosis fungoides: progression towards Sézary syndrome reversed with chlorambucil.
    Clinical and experimental dermatology, 1983, Volume: 8, Issue:4

    Topics: Aged; Chlorambucil; Humans; Male; Mycosis Fungoides; Sezary Syndrome

1983
Composite mycosis fungoides and B-cell chronic lymphocytic leukemia.
    Annals of diagnostic pathology, 2002, Volume: 6, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Chlorambucil; Combined Modality Therapy;

2002
[Chemotherapy in non-Hodgkin's lymphomas (author's transl)].
    Strahlentherapie, 1977, Volume: 153, Issue:5

    Topics: Antineoplastic Agents; Bleomycin; Burkitt Lymphoma; Chlorambucil; Cyclophosphamide; Doxorubicin; Dru

1977
Mycosis fungoides-case report.
    The Journal of the Kentucky Medical Association, 1975, Volume: 73, Issue:3

    Topics: Chlorambucil; Cyclophosphamide; Mycosis Fungoides; Vincristine

1975
Functional properties in Sézary cells with an unusual phenotype.
    Clinical immunology and immunopathology, 1985, Volume: 37, Issue:3

    Topics: Aged; Antibodies, Monoclonal; Chlorambucil; Dermatitis, Exfoliative; Drug Therapy, Combination; Huma

1985
A histologically occult lymphoma revealed by electron microscopy.
    Cutis, 1985, Volume: 35, Issue:3

    Topics: Aged; Biopsy; Chlorambucil; Demeclocycline; Diagnosis, Differential; Humans; Lymphoma; Male; Microsc

1985
Chlorambucil in mycosis fungoides. Report of a case of successful treatment.
    Acta dermato-venereologica, 1968, Volume: 48, Issue:1

    Topics: Aged; Chlorambucil; Chronic Disease; Humans; Male; Mycosis Fungoides

1968
[Hematodermia. Generalized zona].
    Bulletin de la Societe francaise de dermatologie et de syphiligraphie, 1967, Volume: 74, Issue:4

    Topics: Aged; Betamethasone; Chlorambucil; Dermatitis, Exfoliative; Encephalitis; Herpes Zoster; Humans; Inj

1967
Pneumocystitis carinii pneumonia: percutaneous lung biopsy and review of literature.
    Chest, 1971, Volume: 60, Issue:2

    Topics: Adolescent; Adult; Agammaglobulinemia; Amphotericin B; Anuria; Azathioprine; Biopsy; Bis-Trimethylam

1971
[Mycosis fungoides. A form of pleuropulmonary origin with cutaneous sclerodermiform manifestations. Treatment by application of nitrogen mustard].
    Bulletin de la Societe francaise de dermatologie et de syphiligraphie, 1971, Volume: 78, Issue:6

    Topics: Chlorambucil; Cortisone; Humans; Male; Mechlorethamine; Middle Aged; Mycosis Fungoides; Skin Neoplas

1971