chlorambucil has been researched along with Muscular Atrophy, Spinal in 1 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Muscular Atrophy, Spinal: A group of disorders marked by progressive degeneration of motor neurons in the spinal cord resulting in weakness and muscular atrophy, usually without evidence of injury to the corticospinal tracts. Diseases in this category include Werdnig-Hoffmann disease and later onset SPINAL MUSCULAR ATROPHIES OF CHILDHOOD, most of which are hereditary. (Adams et al., Principles of Neurology, 6th ed, p1089)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with chlorambucil and prednisone improved the patient's function from being wheelchair bound to walking unaided." | 5.30 | Improvement of myelopathy in Sjögren's syndrome with chlorambucil and prednisone therapy. ( O'Duffy, JD; Rodriguez, M; Wright, RA, 1999) |
| "Treatment with chlorambucil and prednisone improved the patient's function from being wheelchair bound to walking unaided." | 1.30 | Improvement of myelopathy in Sjögren's syndrome with chlorambucil and prednisone therapy. ( O'Duffy, JD; Rodriguez, M; Wright, RA, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wright, RA | 1 |
| O'Duffy, JD | 1 |
| Rodriguez, M | 1 |
1 other study available for chlorambucil and Muscular Atrophy, Spinal
| Article | Year |
|---|---|
Improvement of myelopathy in Sjögren's syndrome with chlorambucil and prednisone therapy.
Topics: Adult; Chlorambucil; Drug Therapy, Combination; Glucocorticoids; Humans; Magnetic Resonance Imaging; | 1999 |