chlorambucil has been researched along with Metastase in 107 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A clinical protocol outline of a study randomizing prednimustine v doxorubicin in patients with metastatic breast cancer is presented." | 9.06 | A randomized comparative study of prednimustine and doxorubicin in patients with metastatic breast cancer. ( Allegra, JC, 1986) |
| "Thirty-four women with first recurrence of breast cancer were randomized into two groups, and received either Diethylstilbestrol (DES) 5 mg orally (PO) t." | 9.04 | Comparison of DES vs DES + chlorambucil in women with first recurrence of breast cancer. ( Harvey, HA; Holzer, D; Lipton, A, 1979) |
| "Thirty-three patients with metastatic breast cancer received 135 cycles of chemotherapy consisting of mitoxantrone, methotrexate and chlorambucil." | 7.68 | Mitoxantrone, methotrexate and chlorambucil in metastatic breast cancer, a combination with relatively low subjective toxicity. ( Burghouts, JT, 1990) |
| "Thirteen consecutive patients with inoperable recurrent malignant melanoma were treated by immunochemotherapy with the use of chlorambucil noncovalently bound to goat or rabbit antihuman melanoma globulins." | 7.65 | Immunochemotherapy of malignant melanoma with chlorambucil-bound antimelanoma globulins: preliminary results in patients with disseminated disease. ( Bodurtha, A; Ghose, T; Guclu, A; MacDonald, AS; Norvell, ST; Tai, J, 1977) |
| "A clinical protocol outline of a study randomizing prednimustine v doxorubicin in patients with metastatic breast cancer is presented." | 5.06 | A randomized comparative study of prednimustine and doxorubicin in patients with metastatic breast cancer. ( Allegra, JC, 1986) |
| "Thirty-four women with first recurrence of breast cancer were randomized into two groups, and received either Diethylstilbestrol (DES) 5 mg orally (PO) t." | 5.04 | Comparison of DES vs DES + chlorambucil in women with first recurrence of breast cancer. ( Harvey, HA; Holzer, D; Lipton, A, 1979) |
| "Thirty-three patients with metastatic breast cancer received 135 cycles of chemotherapy consisting of mitoxantrone, methotrexate and chlorambucil." | 3.68 | Mitoxantrone, methotrexate and chlorambucil in metastatic breast cancer, a combination with relatively low subjective toxicity. ( Burghouts, JT, 1990) |
| "Thirteen consecutive patients with inoperable recurrent malignant melanoma were treated by immunochemotherapy with the use of chlorambucil noncovalently bound to goat or rabbit antihuman melanoma globulins." | 3.65 | Immunochemotherapy of malignant melanoma with chlorambucil-bound antimelanoma globulins: preliminary results in patients with disseminated disease. ( Bodurtha, A; Ghose, T; Guclu, A; MacDonald, AS; Norvell, ST; Tai, J, 1977) |
| "Cell-surface localizing heterologous antibodies against the mouse EL4 lymphoma and a human malignant melanoma could be bound to chlorambucil without causing the loss of the alkylating activity of chlorambucil or interfering with the reactivity of the antibodies with their respective tumour cells." | 3.65 | Immunochemotherapy of cancer with chlorambucil-carrying antibody. ( Bodurtha, A; Cameron, D; Ghose, T; Guclu, A; MacDonald, AS; Norvell, ST, 1972) |
| "A median of two cycles were given until disease progression or grade 3/4 toxicity." | 2.71 | Low-dose continuous chemotherapy for metastatic melanoma: a phase II trial. ( Neville, F; Nystrom, ML; Oliver, RT; Shamash, J; Steele, JP, 2003) |
| "Since in the treatment of advanced breast cancer chemotherapy and the various hormonal manipulations seem recently to have reached a plateau of effectiveness when used alone, it is widely assumed that the combination of both treatment modalities could improve therapeutic results." | 2.65 | [Simultaneous or sequential hormono/chemotherapy and a comparison of various polychemotherapies in the treatment of metastatic breast cancer]. ( Alberto, P; Beer, M; Brunner, KW; Cavalli, F; Jungi, WF; Martz, G; Mermillod, B; Obrecht, JP, 1982) |
| "Surgery combined with chemotherapy was applied in 34 out of 178 patients (19." | 1.29 | Chemotherapy combined with surgery in the treatment of gestational trophoblastic disease (GTD). ( Kietlińska, Z; Sablińska, B; Zieliński, J, 1993) |
| "Dysgerminomas are highly sensitive not only to irradiation but also to chemotherapy." | 1.27 | [Chemotherapy of dysgerminoma]. ( Brökelmann, J; Hartlapp, JH, 1987) |
| "Thirteen cases of acute nonlymphocytic leukemia occurred among 5455 patients, as compared to 0." | 1.26 | Acute leukemia after alkylating-agent therapy of ovarian cancer. ( Fraumeni, JF; Hoover, R; Reimer, RR; Young, RC, 1977) |
| "Estramustine has been shown previously to be an effective drug in the treatment of metastatic prostatic cancer, demonstrating significant objective and subjective responses in long-term non-randomized trials and in other randomized trials." | 1.26 | The use of estramustine and prednimustine versus prednimustine alone in advanced metastatic prostatic cancer patients who have received prior irradiation. ( Chu, TM; Gaeta, JF; Gibbons, RP; Johnson, DE; Loening, SA; Murphy, GP; Prout, GR; Saroff, J; Schmidt, JD; Scott, WW; Slack, N; Soloway, MS; Wajsman, Z, 1979) |
| "Primary testicular neoplasms are not common childhood tumors, comprising about 1% of all childhood malignancies [1]." | 1.26 | Childhood embryonal carcinoma of testis, report of two unusual cases, and the implication on clinical management. ( Chu, JY; DeMello, D; McElfresh, AE; O'Connor, DM; Razek, AA, 1978) |
| "Generally, metastases responded better than the advanced primaries from which they were derived, except for those from breast tumours." | 1.25 | The influence of site of metastasis on tumour growth and response to chemotherapy. ( Bross, ID; Slack, NH, 1975) |
| " Dosage adjustments were often necessary during the initial phases of therapy." | 1.25 | A controlled study in the use of combined drug therapy for metastatic breast cancer. ( Alberto, P; Brunner, KW; Martz, G; Obrecht, P; Senn, HJ; Sonntag, RW, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 101 (94.39) | 18.7374 |
| 1990's | 5 (4.67) | 18.2507 |
| 2000's | 1 (0.93) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MARTINEZDIAZ, J | 1 |
| Nystrom, ML | 1 |
| Steele, JP | 1 |
| Shamash, J | 1 |
| Neville, F | 1 |
| Oliver, RT | 1 |
| ROSENBLATT, MS | 1 |
| YANOFF, M | 1 |
| RAWSON, AJ | 1 |
| FRECKMAN, HA | 1 |
| FRY, HL | 1 |
| MENDEZ, FL | 1 |
| MAURER, ER | 1 |
| KARNOFSKY, DA | 1 |
| HARMAN, JB | 1 |
| BREWER, JI | 1 |
| GERBIE, AB | 1 |
| DOLKART, RE | 1 |
| SKOM, JH | 1 |
| NAGLE, RG | 1 |
| TOROK, EE | 1 |
| HORWITZ, H | 1 |
| WRIGHT, TL | 1 |
| PERRY, H | 1 |
| BARRETT, CM | 1 |
| APPERT, O | 1 |
| EDMONDS, LC | 1 |
| CARRERA, GM | 1 |
| LEBHERZ, TB | 1 |
| PARKER, RT | 3 |
| Mackenzie, AR | 1 |
| Stehlin, JS | 1 |
| Hills, WJ | 1 |
| Rufino, C | 1 |
| Ludwig, C | 1 |
| Vugrin, D | 2 |
| Whitmore, WF | 1 |
| Golbey, RB | 3 |
| Lurain, JR | 1 |
| Piver, MS | 2 |
| Jones, WB | 2 |
| Beckley, S | 1 |
| Wajsman, LZ | 1 |
| Slack, NH | 2 |
| Murphy, GP | 2 |
| Cavalli, F | 3 |
| Alberto, P | 5 |
| Jungi, F | 2 |
| Brunner, K | 1 |
| Martz, G | 5 |
| Kaufmann, M | 1 |
| Fournier, DV | 1 |
| Sievers, H | 1 |
| Staib, I | 1 |
| Wöllgens, P | 1 |
| Nedden, R | 1 |
| Lochbühler, H | 1 |
| Queisser, W | 1 |
| Christmann, D | 1 |
| Bühner, R | 1 |
| Pfuhl, PJ | 1 |
| Henningsen, B | 1 |
| Kuttig, H | 1 |
| Wysocki, S | 1 |
| Thüre, D | 1 |
| Köhler, C | 1 |
| Drings, P | 1 |
| Jungi, WF | 2 |
| Senn, HJ | 3 |
| Amgwerd, R | 1 |
| Hochuli, E | 1 |
| Beer, M | 1 |
| Obrecht, JP | 1 |
| Mermillod, B | 1 |
| Brunner, KW | 5 |
| Bajorin, DF | 1 |
| Motzer, RJ | 1 |
| Bosl, GJ | 2 |
| Hammond, CB | 4 |
| Olt, GJ | 1 |
| Sablińska, B | 1 |
| Kietlińska, Z | 1 |
| Zieliński, J | 1 |
| Culine, S | 1 |
| Abs, L | 1 |
| Terrier-Lacombe, MJ | 1 |
| Théodore, C | 1 |
| Wibault, P | 1 |
| Droz, JP | 1 |
| Merrin, C | 1 |
| Lewis, JL | 1 |
| Lehr, M | 1 |
| Everall, KD | 1 |
| Dowd, P | 1 |
| Davies, DA | 1 |
| O'Neill, GJ | 1 |
| Rowland, GF | 1 |
| Becker, RL | 1 |
| Avioli, LV | 1 |
| Valdez, VA | 1 |
| Planas, AT | 1 |
| Lopez, VF | 1 |
| Goldberg, M | 1 |
| Herrera, NE | 1 |
| Sonntag, RW | 3 |
| Obrecht, P | 2 |
| Maurice, P | 1 |
| Reimer, RR | 1 |
| Hoover, R | 1 |
| Fraumeni, JF | 1 |
| Young, RC | 1 |
| Reynolds, TF | 1 |
| Gibbons, RP | 1 |
| Johnson, DE | 1 |
| Prout, GR | 1 |
| Schmidt, JD | 1 |
| Soloway, MS | 1 |
| Loening, SA | 1 |
| Chu, TM | 1 |
| Gaeta, JF | 1 |
| Saroff, J | 1 |
| Wajsman, Z | 1 |
| Slack, N | 1 |
| Scott, WW | 1 |
| Holzer, D | 1 |
| Harvey, HA | 1 |
| Lipton, A | 1 |
| Pratt, RA | 1 |
| Di Chiro, G | 1 |
| Weed, JC | 1 |
| Chu, JY | 1 |
| O'Connor, DM | 1 |
| DeMello, D | 1 |
| Razek, AA | 1 |
| McElfresh, AE | 1 |
| Schnitzler, M | 1 |
| Neher, G | 1 |
| Marquart, KH | 1 |
| Cziráki, L | 2 |
| OO, M | 2 |
| Ghose, T | 3 |
| Norvell, ST | 3 |
| Guclu, A | 3 |
| Bodurtha, A | 2 |
| Tai, J | 1 |
| MacDonald, AS | 3 |
| O'Neill, E | 1 |
| Pelegrina, I | 1 |
| Vicens, R | 1 |
| Almodóvar, AR | 1 |
| Baumgartner, G | 1 |
| Farmer, W | 1 |
| Ravin, C | 1 |
| Schachter, EN | 1 |
| Barlow, JJ | 1 |
| Lee, FJ | 1 |
| Vongtama, V | 1 |
| Bross, ID | 1 |
| Gilbert, HA | 1 |
| Yettra, M | 1 |
| Gordon, J | 1 |
| Kagan, AR | 1 |
| Burghouts, JT | 1 |
| Garin, AM | 1 |
| Lichinitser, MR | 1 |
| Khlebnov, AV | 1 |
| Tyulyandin, SA | 1 |
| Leitner, SP | 1 |
| Atlas, SA | 1 |
| Sealey, JE | 1 |
| Preibisz, JJ | 1 |
| Scheiner, E | 1 |
| Taylor, G | 1 |
| Perry, DJ | 1 |
| Knight, RD | 1 |
| Dawson, NA | 1 |
| Skoog, SJ | 1 |
| McLeod, DG | 1 |
| Hall, RR | 1 |
| Calvert, AH | 1 |
| De Stavola, B | 1 |
| Freedman, LS | 1 |
| Goodman, S | 1 |
| Kaye, S | 1 |
| Rogers, AC | 1 |
| Takamizawa, H | 1 |
| Sekiya, S | 1 |
| Kobayashi, O | 1 |
| Matsui, H | 1 |
| Allegra, JC | 1 |
| Brökelmann, J | 1 |
| Hartlapp, JH | 1 |
| Lajos, L | 1 |
| Székely, J | 1 |
| Major, A | 1 |
| Balogh, S | 1 |
| Bücs, G | 1 |
| Gibson, GR | 1 |
| Skinner, DG | 1 |
| Leadbetter, WF | 1 |
| Wilkins, EW | 1 |
| Bonadonna, G | 1 |
| van der Werf-Messing, B | 1 |
| Rathert, P | 1 |
| Terhorst, B | 1 |
| Lutzeyer, W | 1 |
| Grant, RM | 1 |
| Mackie, R | 1 |
| Cochran, AJ | 1 |
| Murray, EL | 1 |
| Hoyle, D | 1 |
| Ross, C | 1 |
| Semenovskiĭ, AV | 1 |
| Molander, DW | 1 |
| Villasanta, U | 1 |
| Bloedorn, FG | 1 |
| Woodruff, JD | 2 |
| Protos, P | 1 |
| Peterson, WF | 1 |
| Berenbaum, MC | 1 |
| Sheard, CE | 1 |
| Reittie, JR | 1 |
| Bundick, RV | 1 |
| Johnson, FD | 2 |
| Jacobs, EM | 2 |
| Ryssel, HJ | 1 |
| Wedemeyer, PP | 1 |
| White, JG | 1 |
| Nesbit, ME | 1 |
| Aust, JB | 1 |
| Leonard, AS | 1 |
| D'Angio, GJ | 1 |
| Krivit, W | 1 |
| Li, MC | 1 |
| Furnari, S | 1 |
| Pavone-Macaluso, M | 1 |
| Veroux, G | 1 |
| Mattea, E | 1 |
| Ober, WB | 1 |
| Edgcomb, JH | 1 |
| Price, EB | 1 |
| Borchert, LG | 1 |
| Tyrey, L | 1 |
| Creasman, WT | 1 |
| Vahlensieck, W | 1 |
| Weissbach, L | 1 |
| Ruffner, BW | 1 |
| Davis, HL | 1 |
| Prout, MN | 1 |
| McKenna, PJ | 1 |
| Cole, DR | 1 |
| Korbitz, BC | 1 |
| Brocheriou, C | 1 |
| Guilbert, F | 1 |
| Rouchon, C | 1 |
| Benoist, M | 1 |
| Chikhani, P | 1 |
| Cameron, D | 1 |
| Thornes, RD | 1 |
| Moncada, R | 1 |
| Cooper, RA | 1 |
| Garces, M | 1 |
| Badrinath, K | 1 |
| Goldenberg, IS | 1 |
| McMahan, CA | 1 |
| Escher, GC | 1 |
| Volk, H | 1 |
| Ansfield, FJ | 1 |
| Olson, KB | 1 |
| Dees, JE | 1 |
| Nogales, FF | 1 |
| Oliva, HA | 1 |
| Julian, CG | 1 |
| Senyszyn, JJ | 1 |
| Johnson, RE | 1 |
| Curran, RE | 1 |
| Fracchia, AA | 1 |
| Farrow, JH | 1 |
| Adam, YG | 1 |
| Monroy, J | 1 |
| Knapper, WH | 1 |
| Lleander, VC | 1 |
| Goldstein, G | 1 |
| Horsley, JS | 1 |
| Shingleton, WW | 1 |
| Sedransk, N | 1 |
| Johnson, RO | 1 |
| Biran, S | 1 |
| Herishianu, Y | 1 |
| Henefer, EP | 1 |
| Nelson, JF | 1 |
| Beaupre, EM | 1 |
| Haab, OP | 1 |
| Stern, OS | 1 |
| Tulgan, H | 1 |
| Budnitz, J | 1 |
| Haidak, G | 1 |
| Moore, CA | 1 |
| Jenkin, RD | 1 |
| Müller-Grotjan, H | 1 |
| Liegl, O | 1 |
6 reviews available for chlorambucil and Metastase
| Article | Year |
|---|---|
Seminoma.
Topics: Adult; Aging; Castration; Chlorambucil; Cryptorchidism; Cyclophosphamide; Dysgerminoma; Humans; Male | 1977 |
Chemotherapy of testicular tumors.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Chlorambucil; Dactinomycin; Dysgermin | 1971 |
[Chemotherapy of trophoblastic disease].
Topics: Chemotherapy, Cancer, Regional Perfusion; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Cyc | 1974 |
Trophoblastic disease: natural history, diagnosis, and treatment.
Topics: Alkylating Agents; Aminopterin; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; | 1971 |
Calcified metastases from malignant ovarian neoplasm. Review of the literature.
Topics: Abdominal Neoplasms; Adult; Aged; Axilla; Biopsy; Breast Neoplasms; Calcinosis; Chlorambucil; Cystad | 1974 |
The role of chemotherapy in the treatment of primary ovarian malignancy.
Topics: Alkylating Agents; Antimetabolites; Antineoplastic Agents; Ascites; Chlorambucil; Chromium; DNA Repl | 1969 |
13 trials available for chlorambucil and Metastase
| Article | Year |
|---|---|
Low-dose continuous chemotherapy for metastatic melanoma: a phase II trial.
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylatin | 2003 |
Chemotherapy in metastatic, hormone refractory prostatic cancer using chlorambucil in combination with prednisolone versus conjugate, prednimustine (Leo 1031).
Topics: Aged; Antineoplastic Agents; Chlorambucil; Clinical Trials as Topic; Drug Therapy, Combination; Huma | 1981 |
Hormono-chemotherapy versus hormonotherapy followed by chemotherapy in the treatment of disseminated breast cancer.
Topics: Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Clinical Trials as Topic; Doxorubicin; Drug A | 1980 |
Adjuvant chemotherapy with chlorambucil and 5-fluorouracil in primary breast cancer (Cooperative Study Heidelberg).
Topics: Breast Neoplasms; Chlorambucil; Clinical Trials as Topic; Drug Therapy, Combination; Female; Fluorou | 1980 |
Divergent effect of adjuvant chemo-immunotherapy on recurrence rates in node-negative and node-positive breast cancer patients.
Topics: BCG Vaccine; Breast Neoplasms; Chlorambucil; Clinical Trials as Topic; Drug Therapy, Combination; Fe | 1980 |
[Simultaneous or sequential hormono/chemotherapy and a comparison of various polychemotherapies in the treatment of metastatic breast cancer].
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Castration; Chlorambucil; Clinical Trials as T | 1982 |
Combined chemo- and hormonal therapy in advanced breast cancer.
Topics: Antineoplastic Agents; Breast Neoplasms; Castration; Chlorambucil; Clinical Trials as Topic; Cycloph | 1977 |
Comparison of DES vs DES + chlorambucil in women with first recurrence of breast cancer.
Topics: Aged; Breast Neoplasms; Chlorambucil; Diethylstilbestrol; Drug Therapy, Combination; Female; Humans; | 1979 |
A randomized comparative study of prednimustine and doxorubicin in patients with metastatic breast cancer.
Topics: Breast Neoplasms; Chlorambucil; Clinical Trials as Topic; Doxorubicin; Female; Humans; Neoplasm Meta | 1986 |
Results of administering B.C.G. to patients with melanoma.
Topics: Adult; Aged; Antibodies, Neoplasm; BCG Vaccine; Blood Cell Count; Cell Migration Inhibition; Chloram | 1974 |
Oral anticoagulant therapy of human cancer.
Topics: Administration, Oral; Anticoagulants; Antineoplastic Agents; Breast Neoplasms; Busulfan; Chlorambuci | 1974 |
Treatment of metastatic Ewing's sarcoma with actinomycin D (NSC-3053).
Topics: Adolescent; Adult; Child; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Dactinomycin; Hu | 1970 |
[Experiences with cytostatic combination therapy in hormone-resistant metastasizing breast cancer].
Topics: Antineoplastic Agents; Blood Platelets; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Female; He | 1969 |
88 other studies available for chlorambucil and Metastase
| Article | Year |
|---|---|
[ON HODGKIN'S DISEASE. PERSONAL EXPERIENCE].
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Aziridines; Biopsy; Chlorambucil; Classification; Hodg | 1964 |
Chemical treatment of metastatic malignant teratoma of the testicle.
Topics: Chlorambucil; Humans; Lung Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Nitrofurazone; Terato | 1963 |
PELIOSIS HEPATIS. AN ANATOMIC STUDY WITH DEMONSTRATION OF TWO VARIETIES.
Topics: Anatomy; Chlorambucil; Classification; Cyclophosphamide; Dactinomycin; Femoral Fractures; Geriatrics | 1964 |
CHLORAMBUCIL-PREDNISOLONE THERAPY FOR DISSEMINATED BREAST CARCINOMA.
Topics: Adrenal Cortex Hormones; Alkylating Agents; Antineoplastic Agents; Biomedical Research; Breast Neopl | 1964 |
NONSURGICAL TREATMENT OF PULMONARY CANCER.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adrenal Cortex Hormones; Alkylating Agents; Antineoplastic Agen | 1964 |
THE TREATMENT OF INCURABLE MALIGNANT DISEASE.
Topics: Adrenalectomy; Androgens; Breast Neoplasms; Busulfan; Chlorambucil; Estrogens; Heroin; Hormones; Hum | 1964 |
CHEMOTHERAPY IN TROPHOBLASTIC DISEASES.
Topics: Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; Drug Therapy; Female; Gestation | 1964 |
"SUPPRESSIVE" CHEMOTHERAPY IN BRONCHOGENIC CARCINOMA: A RANDOMIZED PROSPECTIVE CLINICAL TRIAL.
Topics: Adenocarcinoma; Biomedical Research; Carcinoma; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; C | 1965 |
[CYTOSTATIC TREATMENT OF A MALIGNANT EMBRYONAL MIXED TESTICULAR TUMOR].
Topics: Chlorambucil; Dactinomycin; Drug Therapy; Humans; Lung Neoplasms; Male; Methotrexate; Neoplasm Metas | 1965 |
EXTRAGENITAL CHORIOCARCINOMA.
Topics: Autopsy; Brain Neoplasms; Child; Chlorambucil; Choriocarcinoma; Dactinomycin; Drug Therapy; Epistaxi | 1965 |
CARCINOMA OF THE OVARY.
Topics: Adenocarcinoma; Chlorambucil; Dactinomycin; Drug Therapy; Female; Humans; Lung Neoplasms; Methotrexa | 1965 |
Chemotherapy of metastatic testis cancer. Results in 154 patients.
Topics: Adult; Antibiotics, Antineoplastic; Antimetabolites; Chlorambucil; Choriocarcinoma; Dactinomycin; Dy | 1966 |
Disseminated melanoma. Biologic behavior and treatment.
Topics: Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Dactinomycin; Fluorouracil; Humans; Hydrazine | 1967 |
[The meaning of maintenance therapy in oncology].
Topics: Breast Neoplasms; Chlorambucil; Hodgkin Disease; Leukemia, Myeloid, Acute; Lymphoma; Methotrexate; N | 1980 |
VAB-6 combination chemotherapy without maintenance in treatment of disseminated cancer of the testis.
Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; | 1983 |
Metastatic gestational trophoblastic disease: secondary chemotherapy.
Topics: Antineoplastic Agents; Chlorambucil; Dactinomycin; Drug Therapy, Combination; Female; Humans; Methot | 1980 |
Management of low-risk metastatic gestational trophoblastic disease.
Topics: Antineoplastic Agents; Chlorambucil; Dactinomycin; Drug Therapy, Combination; Female; Humans; Hyster | 1981 |
Germ cell tumors.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Combined | 1994 |
Gestational trophoblastic disease.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug A | 1994 |
Chemotherapy combined with surgery in the treatment of gestational trophoblastic disease (GTD).
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Chorioca | 1993 |
Cisplatin-based chemotherapy in advanced seminoma: the Institut Gustave Roussy experience.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bleomycin; Chl | 1998 |
Monitor of chemotherapy in gestational trophoblastic neoplasm by radioimmunoassay of the beta-subunit of human chorionic gonadotropin.
Topics: Adult; Antineoplastic Agents; Biological Assay; Bleomycin; Chlorambucil; Choriocarcinoma; Chorionic | 1975 |
Letter: Chemotherapy after mastectomy.
Topics: Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Drug Evaluation; Drug Thera | 1976 |
Treatment of melanoma by passive humoral immunotherapy using antibody drug synergism.
Topics: Animals; Antineoplastic Agents; Chlorambucil; Drug Synergism; Goats; Humans; Immunoglobulins; Immuno | 1977 |
Gestational trophoblastic disease.
Topics: Adult; Brain Neoplasms; Cerebral Hemorrhage; Chlorambucil; Choriocarcinoma; Dactinomycin; Female; He | 1977 |
Adenosarcoma of uterus and ovary: a clinicopathologic study of two cases.
Topics: Adult; Chlorambucil; Cyclophosphamide; Cytoplasm; Female; Humans; Middle Aged; Neoplasm Metastasis; | 1979 |
Acute leukemia after alkylating-agent therapy of ovarian cancer.
Topics: Acute Disease; Alkylating Agents; Altretamine; Chlorambucil; Cyclophosphamide; Female; Fluorouracil; | 1977 |
Chemotherapy of metastatic germ cell tumors.
Topics: Antineoplastic Agents; Chlorambucil; Cisplatin; Cyclophosphamide; Dactinomycin; Drug Therapy, Combin | 1979 |
The use of estramustine and prednimustine versus prednimustine alone in advanced metastatic prostatic cancer patients who have received prior irradiation.
Topics: Chlorambucil; Drug Therapy, Combination; Estramustine; Humans; Male; Nausea; Neoplasm Metastasis; Ni | 1979 |
Cerebral necrosis following irradiation and chemotherapy for metastatic choriocarcinoma.
Topics: Adult; Antineoplastic Agents; Brain; Brain Diseases; Brain Neoplasms; Chlorambucil; Choriocarcinoma; | 1977 |
Childhood embryonal carcinoma of testis, report of two unusual cases, and the implication on clinical management.
Topics: Castration; Child, Preschool; Chlorambucil; Cyclophosphamide; Dactinomycin; Doxorubicin; Humans; Inf | 1978 |
[Contribution on the severity of giant cell tumors].
Topics: Chlorambucil; Doxorubicin; Female; Giant Cell Tumors; Humans; Lung Neoplasms; Middle Aged; Neoplasm | 1978 |
Combination therapy in metastatic breast cancer.
Topics: Adult; Aged; Breast Neoplasms; Chlorambucil; Drug Therapy, Combination; Female; Humans; Middle Aged; | 1977 |
Immunochemotherapy of malignant melanoma with chlorambucil-bound antimelanoma globulins: preliminary results in patients with disseminated disease.
Topics: Adolescent; Adult; Aged; Antibodies, Neoplasm; Chlorambucil; Dacarbazine; Female; Humans; Hypersensi | 1977 |
[Combined leukeran-prednisolone therapy in metastasizing breast cancer].
Topics: Adenocarcinoma; Adult; Aged; Breast Neoplasms; Chlorambucil; Drug Therapy, Combination; Female; Huma | 1977 |
Normal pregnancy and delivery after cerebral metastases of choriocarcinoma: Case report.
Topics: Adolescent; Brain Neoplasms; Chlorambucil; Choriocarcinoma; Dactinomycin; Drug Therapy, Combination; | 1976 |
[Cytostatic therapy of inoperable carcinomas].
Topics: Breast Neoplasms; Bronchial Neoplasms; Chlorambucil; Choriocarcinoma; Cyclophosphamide; Dactinomycin | 1976 |
Hyperlucent lung after radiation therapy.
Topics: Angiography; Bone Neoplasms; Breast Neoplasms; Chlorambucil; Dyspnea, Paroxysmal; Female; Humans; Lu | 1975 |
Sequential therapy for advanced ovarian adenocarcinoma: operation, chemotherapy, second-look laparotomy, and radiation therapy.
Topics: Adenocarcinoma; Chlorambucil; Cyclophosphamide; Dactinomycin; Female; Fluorouracil; Laparotomy; Melp | 1975 |
Immunochemotherapy of human malignant melanoma with chlorambucil-carrying antibody.
Topics: Aged; Animals; Antibodies, Neoplasm; Antigens, Neoplasm; Cell Membrane; Chlorambucil; Cross Reaction | 1975 |
The influence of site of metastasis on tumour growth and response to chemotherapy.
Topics: Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Female; Fluorouracil; Genital Neoplasms, Fema | 1975 |
A controlled study in the use of combined drug therapy for metastatic breast cancer.
Topics: Age Factors; Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Drug Therapy, | 1975 |
On long-term survivals in non-Hodgkin's lymphoma with 'gentle' treatment.
Topics: Adult; Aged; Child; Chlorambucil; Female; Follow-Up Studies; Humans; Lymph Nodes; Lymphoma; Male; Mi | 1976 |
Mitoxantrone, methotrexate and chlorambucil in metastatic breast cancer, a combination with relatively low subjective toxicity.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Ch | 1990 |
Efficacy of combination chemotherapy including Platidiam in the treatment of malignant testicular tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Cyclophosphamide | 1987 |
Altered renin and aldosterone excretion in patients treated for metastatic germ cell tumours.
Topics: Aldosterone; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Cyc | 1987 |
Clinical predictors of response in metastatic germ cell tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Cyclophosphamide | 1988 |
Phase II trials in metastatic bladder cancer.
Topics: Aged; Antineoplastic Agents; Carboplatin; Chlorambucil; Drug Evaluation; Humans; Neoplasm Metastasis | 1986 |
Chemotherapy for gestational trophoblastic tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropi | 1987 |
[Chemotherapy of dysgerminoma].
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined | 1987 |
[Importance of chemotherapeutic agents in the treatment of malignant trophoblast tumors].
Topics: Adnexa Uteri; Adult; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; Female; Hu | 1969 |
Lymphangiography as a diagnostic aid. Report of a case.
Topics: Abdomen; Chlorambucil; Dactinomycin; Dysgerminoma; Humans; Hydronephrosis; Lymph Nodes; Lymphography | 1964 |
The surgical management of testis tumors metastatic to the lung: a report of 10 cases with subsequent resection of from one to seven pulmonary metastases.
Topics: Adolescent; Adult; Castration; Child; Chlorambucil; Dactinomycin; Follow-Up Studies; Humans; Lung Ne | 1971 |
The treatment of pulmonary metastases of malignant teratoma of the testis.
Topics: Chlorambucil; Dactinomycin; Humans; Lung Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Pneumon | 1973 |
[Bleomycin for malignant tumours of the genitals of the male (author's transl)].
Topics: Adrenal Cortex Hormones; Adult; Age Factors; Aged; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil | 1974 |
Palliative treatment of metastatic tumors of the soft somatic tissues with irradiation and chemotherapy.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bone Marrow Examination; Child, Preschool; Chlorambu | 1966 |
Operation, external irradiation, radioactive isotopes, and chemotherapy in treatment of metastatic ovarian malignancies.
Topics: Ascites; Carcinoma; Chlorambucil; Cyclophosphamide; Dactinomycin; Female; Fluorouracil; Follow-Up St | 1968 |
Ovarian teratomas. Relationship of histologic and ontogenic factors to prognosis.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Chlorambucil; Choriocarcinoma; Dactinomycin | 1968 |
The growth of human tumours in immunosuppressed mice and their response to chemotherapy.
Topics: Animals; Chlorambucil; Cyclophosphamide; Dactinomycin; Disease Models, Animal; Female; Fluorouracil; | 1974 |
Chemotherapy of metastatic malignant melanoma. Experience with 73 patients.
Topics: Adult; Aged; Antineoplastic Agents; Chlorambucil; Colchicine; Cyclophosphamide; Cytarabine; Eye Neop | 1971 |
[Treatment of choriocarcinoma and malignant testicular neoplasms in internal medicine].
Topics: Chlorambucil; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Dysgerminoma; Humans; Lung Neoplasms; | 1967 |
Resection of metastases in Wilms' tumor: a report of three cases cured of pulmonary and hepatic metastases.
Topics: Child, Preschool; Chlorambucil; Cobalt Isotopes; Dactinomycin; Female; Humans; Infant; Liver Neoplas | 1968 |
Diagnosis and treatment of trophoblastic disease. A report from the Southeastern Regional Center.
Topics: Adult; Antineoplastic Agents; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; D | 1970 |
Cancer chemotherapy in urology.
Topics: Adenocarcinoma; Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites; Chlorambucil; Cobal | 1971 |
The pathology of choriocarcinoma.
Topics: Adolescent; Adult; Age Factors; Animals; Autopsy; Child; Chlorambucil; Choriocarcinoma; Chorionic Go | 1971 |
Treatment of metastatic trophoblastic disease: good and poor prognosis.
Topics: Brain Neoplasms; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; Female; Follow | 1973 |
Operative and cytostatic treatment of germinal tumours of the testis.
Topics: Adolescent; Adult; Antineoplastic Agents; Castration; Child; Child, Preschool; Chlorambucil; Cyclic | 1973 |
Letter: Androgen role in erythroleukemia after treatment with alkylating agents.
Topics: Adult; Alkylating Agents; Androgens; Carcinoma, Intraductal, Noninfiltrating; Chlorambucil; Cytarabi | 1974 |
Tumor conference.
Topics: Adult; Carcinoma, Squamous Cell; Chlorambucil; Female; Humans; Neoplasm Metastasis; Ovarian Neoplasm | 1968 |
Acute leukemia complicating metastatic breast cancer.
Topics: Adult; Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Female; Fluorouracil | 1973 |
[Ewing's sarcoma localized to the mandible. 2 cases].
Topics: Adolescent; Asparaginase; Child; Chlorambucil; Cobalt Radioisotopes; Cyclophosphamide; Female; Human | 1974 |
Immunochemotherapy of cancer with chlorambucil-carrying antibody.
Topics: Aged; Animals; Antibodies; Cell Membrane; Chlorambucil; Fluorescent Antibody Technique; Goats; Human | 1972 |
Secondary chemotherapy of advanced breast cancer.
Topics: Adult; Aged; Breast Neoplasms; Chlorambucil; Female; Humans; Hydrocortisone; Middle Aged; Neoplasm M | 1973 |
Metastatic embryonal cell carcinoma of testis: an apparent 8-year cure.
Topics: Adult; Chlorambucil; Dactinomycin; Humans; Lung Neoplasms; Lymphography; Male; Methotrexate; Neoplas | 1973 |
Peritoneal gliomatosis produced by ovarian teratomas.
Topics: Adult; Chlorambucil; Dactinomycin; Fallopian Tubes; Female; Glioma; Humans; Hysterectomy; Methotrexa | 1974 |
Systemic chemotherapy for advanced breast cancer.
Topics: Adrenal Cortex Hormones; Adult; Aged; Androgens; Antineoplastic Agents; Breast Neoplasms; Chlorambuc | 1970 |
Chemotherapy in the management of metastatic cancer of unknown primary site.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Carcinoma; Carcinoma, Squamous Cell; Chlorambucil; Cyclopho | 1972 |
Chemotherapy of breast carcinoma.
Topics: Adult; Amines; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Female; Fluorouracil; Humans; Imida | 1972 |
Gestational choriocarcinoma.
Topics: Adult; California; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; Female; Huma | 1972 |
Brain involvement in Hodgkin's disease. Report of a case.
Topics: Adolescent; Antineoplastic Agents; Brain Neoplasms; Cerebral Angiography; Chlorambucil; Echoencephal | 1972 |
Palatal enlargement in chronic lymphocytic leukemia: report of case.
Topics: Aged; Chlorambucil; Edema; Humans; Leukemia, Lymphoid; Lymphatic Metastasis; Lymphoma, Non-Hodgkin; | 1970 |
The place of chemotherapy in the treatment of testicular tumors.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Chlorambucil; Choriocarcinoma; Chorionic Gonadot | 1970 |
[Internal cancer therapy: cooperative clinical studies. Principles, organization and first results of the Swiss chemotherapy group].
Topics: Adenocarcinoma; Androgens; Antibiotics, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Car | 1967 |
[Combined chemotherapy in metastatic breast cancer].
Topics: Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Drug Synergism; Female; Hum | 1967 |
Endobronchial presentation of malignant lymphoma.
Topics: Bone Neoplasms; Bronchial Neoplasms; Bronchoscopy; Chlorambucil; Hodgkin Disease; Humans; Male; Mech | 1968 |
Triple chemotherapy in the treatment of metastatic testicular neoplasms.
Topics: Adult; Chlorambucil; Choriocarcinoma; Dactinomycin; Humans; Male; Methotrexate; Neoplasm Metastasis; | 1968 |
Ewing's sarcoma a study of treatment methods.
Topics: Adolescent; Bone Neoplasms; Child; Chlorambucil; Cyclophosphamide; Female; Humans; Male; Mechloretha | 1966 |
[Cytostatic therapy of choroid membrane metastases].
Topics: Aged; Breast Neoplasms; Chlorambucil; Choroid Neoplasms; Cyclophosphamide; Female; Humans; Mastectom | 1966 |