chlorambucil has been researched along with Lymphoma in 157 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Lymphoma: A general term for various neoplastic diseases of the lymphoid tissue.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a nationwide multicenter study, single-agent treatment with prednimustine (PM) was compared with combination chemotherapy with CVP (cyclophosphamide, vincristine, and prednisolone) in patients with stage III-IV non-Hodgkin's lymphoma (NHL) with favorable histology (Rappaport groups nodular lymphocytic poorly differentiated, nodular mixed, and diffuse lymphocytic poorly and well-differentiated)." | 9.06 | Prednimustine v cyclophosphamide-vincristine-prednisolone in the treatment of non-Hodgkin's lymphoma with favorable histopathology: results of a national cancer care program in Sweden. ( Cavallin-Ståhl, E; Möller, TR, 1986) |
| "Prednimustine, a chlorambucil ester of prednisolone, was administered to 16 patients with non-Hodgkin lymphomata (NHL) and 14 patients with chronic lymphocytic leukaemia (CLL), all previously treated with steroids and alkylating agents." | 9.05 | Clinical trial of prednimustine, Leo-1031 (NSC-134087), in patients with non-Hodgkin lymphomata and chronic lymphocytic leukaemia previously treated with steroids and alkylating agents. ( Geisler, CH; Hansen, MM; Nissen, NI; Pedersen-Bjergaard, J, 1980) |
| "24 patients with non-Hodgkin's lymphomas of low-grade malignancy (stage III and IV) were treated either with a single drug (prednimustine) or with combination chemotherapy (cyclophosphamide, vincristine and prednisone)." | 9.05 | Value of prednimustine in treating non Hodgkin's lymphomas of favourable histological type. ( Háber, J; Klener, P, 1985) |
| "The aims of this study were to evaluate the response, outcome and prognostic factors in cats with clinically presumed relapsed low-grade alimentary lymphoma (LGAL) receiving cyclophosphamide as a first-line rescue therapy after failing chlorambucil treatment." | 8.02 | Cyclophosphamide rescue therapy for relapsed low-grade alimentary lymphoma after chlorambucil treatment in cats. ( Borrego, J; Chon, E; Kim, C; Wouda, RM, 2021) |
| "The cytotoxic activity of chlorambucil (Chl) and of chlorambucil-fatty acid conjugates of different degree of unsaturation have been assayed in vitro upon two human lymphoma cell lines and comparatively, upon quiescent and mitogen-activated lymphocytes from healthy blood donors." | 7.68 | Cytotoxicity of chlorambucil and chlorambucil-fatty acid conjugates against human lymphomas and normal human peripheral blood lymphocytes. ( Anel, A; Antonakis, K; Halmos, T; Piñeiro, A; Torres, JM; Uriel, J, 1990) |
| "Fifty-six patients with advanced non-Hodgkin's lymphoma (NHL) were entered into a phase II study of prednimustine, an ester of chlorambucil and prednisolone." | 7.67 | Prednimustine in refractory non-Hodgkin's lymphoma: a phase II study of the Northern California Oncology Group. ( Fisher, K; Forsythe, J; Gandara, DR; Kohler, M; Lewis, B; Redmond, J; Reynolds, R; Wold, HG; Wong, P, 1986) |
| "Forty patients with lymphocytic lymphoma were treated with escalating doses of chlorambucil biweekly starting at a dose of 0." | 7.66 | Biweekly chlorambucil treatment of lymphocytic lymphoma. ( Knospe, WH; Loeb, V, 1980) |
| "Fourty-three of 61 patients suffering from low-grade malignant non-Hodgkin's lymphomas according to the Kiel classification were subjected to an intermittent combination chemotherapy with chlorambucil and prednisone." | 7.66 | Intermittent combination chemotherapy with chlorambucil and prednisone of low-grade malignant non-Hodgkin's lymphomas according to the Kiel classification. ( Garbrecht, M; Stolzenbach, G, 1979) |
| "A cell-surface localizing xenogeneic antibody against an AKR mouse lymphoma of spontaneous origin could be bound to chlorambucil without interference with either the alkylating activity of chlorambucil or the immunologic reactivity of the antibody." | 7.65 | Suppression of an AKR lymphoma by antibody and chlorambucil. ( Ghose, T; Guclu, A; Tai, J, 1975) |
| "Chlorambucil is an anticancer drug with alkylating and immunosuppressive activities." | 5.40 | Chlorambucil and ascorbic acid-mediated anticancer activity and hematological toxicity in Dalton's ascites lymphoma-bearing mice. ( Kalita, S; Prasad, SB; Verma, AK, 2014) |
| "Four patients who developed acute myeloblastic leukemia during the treatment of a non-Hodgkin's lymphoma are described." | 5.26 | Acute myeloid leukemia following non-Hodgkin's lymphoma: danger of prolonged use of chlorambucil as maintenance therapy. ( Dumont, J; Mazabraud, A; Natali, JC; Thiery, JP; Trapet, P; Vilcoq, JR, 1980) |
| "In a nationwide multicenter study, single-agent treatment with prednimustine (PM) was compared with combination chemotherapy with CVP (cyclophosphamide, vincristine, and prednisolone) in patients with stage III-IV non-Hodgkin's lymphoma (NHL) with favorable histology (Rappaport groups nodular lymphocytic poorly differentiated, nodular mixed, and diffuse lymphocytic poorly and well-differentiated)." | 5.06 | Prednimustine v cyclophosphamide-vincristine-prednisolone in the treatment of non-Hodgkin's lymphoma with favorable histopathology: results of a national cancer care program in Sweden. ( Cavallin-Ståhl, E; Möller, TR, 1986) |
| "24 patients with non-Hodgkin's lymphomas of low-grade malignancy (stage III and IV) were treated either with a single drug (prednimustine) or with combination chemotherapy (cyclophosphamide, vincristine and prednisone)." | 5.05 | Value of prednimustine in treating non Hodgkin's lymphomas of favourable histological type. ( Háber, J; Klener, P, 1985) |
| "Prednimustine, a chlorambucil ester of prednisolone, was administered to 16 patients with non-Hodgkin lymphomata (NHL) and 14 patients with chronic lymphocytic leukaemia (CLL), all previously treated with steroids and alkylating agents." | 5.05 | Clinical trial of prednimustine, Leo-1031 (NSC-134087), in patients with non-Hodgkin lymphomata and chronic lymphocytic leukaemia previously treated with steroids and alkylating agents. ( Geisler, CH; Hansen, MM; Nissen, NI; Pedersen-Bjergaard, J, 1980) |
| "This report describes two comparisons of combination chemotherapy (COP) with chlorambucil in the management of Stages III, IV Grade 1 non-Hodgkin's lymphoma." | 5.05 | Chemotherapy in the management of stage III/IV grade 1 non-Hodgkin's lymphomas (Report no 17). ( Hayhoe, FG, 1981) |
| "Sixty-six untreated patients with advanced non-Hodgkin's lymphoma of favourable histological type were allocated alternately to initial treatment with cyclophosphamide, vincristine, and prednisolone or with chlorambucil." | 5.04 | Comparison of combined and single-agent chemotherapy in non-Hodgkin's lymphoma of favourable histological type. ( Beard, ME; Brearley, RL; Crowther, D; Cullen, MH; Lister, TA; Malpas, JS; Stansfeld, AG; Sutcliffe, SB; Whitehouse, JM; Wrigley, PF, 1978) |
| "The aims of this study were to evaluate the response, outcome and prognostic factors in cats with clinically presumed relapsed low-grade alimentary lymphoma (LGAL) receiving cyclophosphamide as a first-line rescue therapy after failing chlorambucil treatment." | 4.02 | Cyclophosphamide rescue therapy for relapsed low-grade alimentary lymphoma after chlorambucil treatment in cats. ( Borrego, J; Chon, E; Kim, C; Wouda, RM, 2021) |
| " We report a case of marginal zone lymphoma complicated by CAIA that responded to rituximab after failing to respond to corticosteroids and chlorambucil." | 3.72 | Refractory cold agglutinin-immunohaemolytic anaemia associated to marginal zone lymphoma responding to rituximab. ( Clavo, M; de Sevilla, AF; Domingo-Doménech, E; González-Barca, E; Grañena, A; Petit, J, 2003) |
| " The panel members discussed the use of valacyclovir (Valtrex) to provide prophylaxis for herpes zoster, trimethoprim/sulfamethoxazole for Pneumocystis, and acyclovir (Zovirax) for varicella zoster." | 3.70 | Infectious complications of pentostatin therapy. ( Cabanillas, F; Dang, N; Drapkin, R; Foss, F; O'Brien, S; Vose, JM, 2000) |
| " In vitro studies of human chronic lymphocytic leukemia cells incubated with theophylline, a phosphodiesterase inhibitor, resulted in downregulation of bcl-2 concomitant with induction of apoptosis." | 3.70 | Theophylline, pentostatin (Nipent), and chlorambucil: a dose-escalation study targeting intrinsic biologic resistance mechanisms in patients with relapsed lymphoproliferative disorders. ( Byrd, JC; Flinn, IW; Goodrich, A; Grever, MR; Lucas, MA; Park, K; Shinn, C; Waselenko, JK; Willis, CR, 2000) |
| "The cytotoxic activity of chlorambucil (Chl) and of chlorambucil-fatty acid conjugates of different degree of unsaturation have been assayed in vitro upon two human lymphoma cell lines and comparatively, upon quiescent and mitogen-activated lymphocytes from healthy blood donors." | 3.68 | Cytotoxicity of chlorambucil and chlorambucil-fatty acid conjugates against human lymphomas and normal human peripheral blood lymphocytes. ( Anel, A; Antonakis, K; Halmos, T; Piñeiro, A; Torres, JM; Uriel, J, 1990) |
| "Fifty-six patients with advanced non-Hodgkin's lymphoma (NHL) were entered into a phase II study of prednimustine, an ester of chlorambucil and prednisolone." | 3.67 | Prednimustine in refractory non-Hodgkin's lymphoma: a phase II study of the Northern California Oncology Group. ( Fisher, K; Forsythe, J; Gandara, DR; Kohler, M; Lewis, B; Redmond, J; Reynolds, R; Wold, HG; Wong, P, 1986) |
| "Fourty-three of 61 patients suffering from low-grade malignant non-Hodgkin's lymphomas according to the Kiel classification were subjected to an intermittent combination chemotherapy with chlorambucil and prednisone." | 3.66 | Intermittent combination chemotherapy with chlorambucil and prednisone of low-grade malignant non-Hodgkin's lymphomas according to the Kiel classification. ( Garbrecht, M; Stolzenbach, G, 1979) |
| " In 1976 she developed a mixed cryoglobulinemia and an immune complex mediated vasculitis manifested by purpura and neuropathy which improved on prednisone and chlorambucil therapy." | 3.66 | Behçet's disease associated with a lymphoproliferative disorder, mixed cryoglobulinemia, and an immune complex mediated vasculitis. ( Houston, KA; McDuffie, FC; O'duffy, JD, 1978) |
| "Biochemical analysis and morphological studies were carried out in six patients with lymphomas during and after withdrawal treatment with chlorambucil, testosterone propionate (TP) and human chorionic gonadotropins (HCG)." | 3.66 | Biochemical changes of the human semen produced by chlorambucil, testosterone propionate and human chorionic gonadotropin administration. ( Calamera, JC; Mancini, RE; Morgenfeld, MC; Vilar, O, 1979) |
| "Forty patients with lymphocytic lymphoma were treated with escalating doses of chlorambucil biweekly starting at a dose of 0." | 3.66 | Biweekly chlorambucil treatment of lymphocytic lymphoma. ( Knospe, WH; Loeb, V, 1980) |
| "A cell-surface localizing xenogeneic antibody against an AKR mouse lymphoma of spontaneous origin could be bound to chlorambucil without interference with either the alkylating activity of chlorambucil or the immunologic reactivity of the antibody." | 3.65 | Suppression of an AKR lymphoma by antibody and chlorambucil. ( Ghose, T; Guclu, A; Tai, J, 1975) |
| "Cell-surface localizing heterologous antibodies against the mouse EL4 lymphoma and a human malignant melanoma could be bound to chlorambucil without causing the loss of the alkylating activity of chlorambucil or interfering with the reactivity of the antibodies with their respective tumour cells." | 3.65 | Immunochemotherapy of cancer with chlorambucil-carrying antibody. ( Bodurtha, A; Cameron, D; Ghose, T; Guclu, A; MacDonald, AS; Norvell, ST, 1972) |
| "These included 4 cases of chronic lymphocytic leukemia (CLL), 5 cases of chronic myelogenous leukemia (CML), 5 cases of malignant lymphoma (ML) and 7 cases of multiple myeloma (MM)." | 2.66 | [Clinical trial of bestrabucil (KM 2210) on hematopoietic malignancies]. ( Katayama, N; Kita, K; Kobayashi, T; Matsuoka, N; Minami, N; Nishikawa, M; Ohno, T; Tanaka, H; Tomeoku, M; Uemura, Y, 1986) |
| "Chlorambucil is an anticancer drug with alkylating and immunosuppressive activities." | 1.40 | Chlorambucil and ascorbic acid-mediated anticancer activity and hematological toxicity in Dalton's ascites lymphoma-bearing mice. ( Kalita, S; Prasad, SB; Verma, AK, 2014) |
| " The optimum dose of chlorambucil has not been defined and there are numerous different dosing schedules available." | 1.32 | High dose chlorambucil in the treatment of lymphoid malignancies. ( Nicolle, A; Proctor, SJ; Summerfield, GP, 2004) |
| " All effects remitted immediately after the final day of the dosing regimen." | 1.32 | Mood alterations in patients treated with chlorambucil. ( Dorr, RT; Hehn, ST; Miller, TP, 2003) |
| "Subsequently, standard chemotherapy for Hodgkin's disease induced complete clinical and biochemical remission." | 1.29 | Suspected malignant lymphoma presenting with widespread granulomatous lesions in bones and lymph nodes and responding to combination chemotherapy. ( Jensen, MK; Johansen, P; Pulczynski, S, 1996) |
| "Three of four patients with Hodgkin's disease responded after relatively short periods of treatment." | 1.27 | Leukocyte interferon as a possible biological response modifier in lymphoproliferative disorders resistant to standard therapy. ( Axelson, JA; Charamella, LJ; Clark, RH; Dimitrov, NV, 1984) |
| "The primary treatment in low-grade malignant lymphomas was a combination of chlorambucil and prednisone: in case of progression or therapeutic failure more aggressive schedules (COP, C-MOPP, HOP, CHOP, BACOP) were used." | 1.27 | [Results of cytostatic polychemotherapy in non-Hodgkin lymphomas]. ( Bliem, J; Denz, H; Hehenwarter, W; Huber, H; Kratzer, H; Michlmayr, G; Nitsche, D; Tschurtschenthaler, G, 1983) |
| "In addition, acute renal failure developed in both patients, and myolysis in one." | 1.27 | Purpura fulminans in pneumococcal sepsis. ( Berneman, ZN; Bieger, R; Bridts, C; Buyssens, N; Hautekeete, ML; Peetermans, ME; Stevens, WJ, 1986) |
| "35 cases of non-Hodgkin malignant lymphomas of head and neck, stages I and II." | 1.27 | [Non-Hodgkin lymphomas of the head and neck, stages I and II. Apropos 35 cases]. ( Beral, HM; Bertrand, JC; Chantelar, JV; Ghenim, C; Guerin, RA; Guilbert, F; Nizri, D; Szpirglas, H; Touboul, E; Zribi, A, 1985) |
| "Data on the possible increased risk of malignancy in rheumatoid arthritis are still being collected, and until further information is available, the use of immunosuppressive drugs, particularly alkylating agents, in the treatment of rheumatoid arthritis should be reserved for patients with severe progressive disease or life-threatening complications." | 1.27 | Incidence of neoplasms in patients with rheumatoid arthritis exposed to different treatment regimens. ( Hazleman, B, 1985) |
| "Of 602 patients treated for non-Hodgkin's lymphomas, 9 developed overt acute nonlymphocytic leukemia or preleukemia with refractory cytopenia and cytogenetic abnormalities of the bone marrow." | 1.27 | Risk of acute nonlymphocytic leukemia and preleukemia in patients treated with cyclophosphamide for non-Hodgkin's lymphomas. Comparison with results obtained in patients treated for Hodgkin's disease and ovarian carcinoma with other alkylating agents. ( Ersbøll, J; Keiding, N; Larsen, MS; Larsen, SO; Nissen, NI; Pedersen-Bjergaard, J; Philip, P; Schultz, H; Sørensen, HM, 1985) |
| "Four patients who developed acute myeloblastic leukemia during the treatment of a non-Hodgkin's lymphoma are described." | 1.26 | Acute myeloid leukemia following non-Hodgkin's lymphoma: danger of prolonged use of chlorambucil as maintenance therapy. ( Dumont, J; Mazabraud, A; Natali, JC; Thiery, JP; Trapet, P; Vilcoq, JR, 1980) |
| "This led to the discovery of a large malignant lymphoma of the nasopharynx." | 1.26 | Malignant lymphoma of thenasopharyns in waldenström's macroglobulinemia: report of a case with severe epistaxis. ( Napoli, VM; Nichols, CW; Wright, RE, 1977) |
| "Low-grade malignant lymphomas are treated best with conventional doses of an alkylating agent." | 1.26 | [Chemotherapy in non-Hodgkin's lymphomas (author's transl)]. ( Schmidt, CG, 1977) |
| " The patients were divided into three groups according to dosage and previous treatment." | 1.26 | Continuous treatment of non-Hodgkin's malignant lymphoma with prednimustine (Leo 1031). ( Håkansson, L; Könyves, I; Lindberg, LG; Möller, T, 1978) |
| " It is suggested that prednisolone plasma levels are as good a parameter of Prednimustine absorption and bioavailability as chlorambucil levels, Prednimustine itself having never been detected in plasma." | 1.26 | Prednisolone plasma levels after oral administration of Prednimustine. Comparison with levels obtained after administration of an equimolar dose of prednisolone. ( Hove, WV; Sayed, A; Vermeulen, A, 1981) |
| "Azathioprine was best tolerated, but gave only medium results whereas procarbazine, as a very potent drug, had the highest rate of side effects (especially depression of bone marrow, infections, gastrointestinal manifestations etc." | 1.25 | [Side effects in immunosuppressive therapy]. ( Thumb, N, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 136 (86.62) | 18.7374 |
| 1990's | 8 (5.10) | 18.2507 |
| 2000's | 8 (5.10) | 29.6817 |
| 2010's | 3 (1.91) | 24.3611 |
| 2020's | 2 (1.27) | 2.80 |
| Authors | Studies |
|---|---|
| Ohmi, A | 3 |
| Tanaka, M | 3 |
| Rinno, J | 3 |
| Tsuboi, M | 3 |
| Chambers, JK | 3 |
| Uchida, K | 3 |
| Goto-Koshino, Y | 3 |
| Tomiyasu, H | 3 |
| Ohno, K | 3 |
| Tsujimoto, H | 3 |
| Kim, C | 1 |
| Wouda, RM | 1 |
| Borrego, J | 1 |
| Chon, E | 1 |
| Giuliano, A | 1 |
| Kalita, S | 1 |
| Verma, AK | 1 |
| Prasad, SB | 1 |
| Nagata, N | 1 |
| Shibata, S | 1 |
| Sakai, H | 1 |
| Konno, H | 1 |
| Takashima, S | 1 |
| Kawabe, M | 1 |
| Mori, T | 1 |
| Kitagawa, H | 1 |
| Washizu, M | 1 |
| Metayer, C | 1 |
| Curtis, RE | 1 |
| Vose, J | 1 |
| Sobocinski, KA | 1 |
| Horowitz, MM | 1 |
| Bhatia, S | 1 |
| Fay, JW | 1 |
| Freytes, CO | 1 |
| Goldstein, SC | 1 |
| Herzig, RH | 1 |
| Keating, A | 1 |
| Miller, CB | 1 |
| Nevill, TJ | 1 |
| Pecora, AL | 1 |
| Rizzo, JD | 1 |
| Williams, SF | 1 |
| Li, CY | 1 |
| Travis, LB | 1 |
| Weisdorf, DJ | 1 |
| GALTON, DA | 2 |
| ISRAELS, LG | 2 |
| NABARRO, JD | 1 |
| TILL, M | 2 |
| DE VRIES, SI | 1 |
| WILTSHAW, E | 1 |
| DOAN, CA | 1 |
| WISEMAN, BK | 1 |
| BOURONCLE, BA | 1 |
| PERRONE, V | 2 |
| FAIELLA, A | 2 |
| ZARRILLI, D | 2 |
| PITNEY, WR | 1 |
| MOLANDER, DW | 1 |
| OSSIPOVSKI, B | 1 |
| WILLIAMS, HM | 1 |
| FEIWEL, M | 1 |
| MUNRO, DD | 1 |
| VIGI, F | 1 |
| BURNINGHAM, RA | 1 |
| RESTREPO, A | 1 |
| PUGH, RP | 1 |
| BROWN, EB | 1 |
| SCHLOSSMAN, SF | 1 |
| KHURI, PD | 1 |
| LESSNER, HE | 1 |
| HARRINGTON, WJ | 1 |
| IRVINE, RA | 1 |
| ROBERTSON, WB | 1 |
| TANIDA, T | 1 |
| PAPAC, RJ | 1 |
| WOOD, DA | 1 |
| KARNOFSKY, DA | 1 |
| HUTCHISON, JL | 1 |
| EZDINLI, EZ | 1 |
| STUTZMAN, L | 2 |
| SMITH, JC | 1 |
| BOLANDE, RP | 1 |
| SBARRA, AJ | 1 |
| SHIRLEY, W | 1 |
| SELVARAJ, RJ | 1 |
| IOUCHI, E | 1 |
| ROSENBAUM, E | 1 |
| LIBANSKY, J | 1 |
| CHUDOMEL, V | 1 |
| BRABEC, V | 1 |
| SOCHMAN, J | 1 |
| CAJANO, A | 1 |
| RABENKO, J | 1 |
| Petit, J | 1 |
| Clavo, M | 1 |
| de Sevilla, AF | 1 |
| González-Barca, E | 1 |
| Domingo-Doménech, E | 1 |
| Grañena, A | 1 |
| Hehn, ST | 1 |
| Dorr, RT | 1 |
| Miller, TP | 1 |
| Nicolle, A | 1 |
| Proctor, SJ | 2 |
| Summerfield, GP | 1 |
| Johnson, SA | 1 |
| Owen, RG | 1 |
| Oscier, DG | 1 |
| Leblond, V | 1 |
| Levy, V | 1 |
| Jaeger, U | 1 |
| Seymour, JF | 1 |
| Lindhagen, E | 1 |
| Nissle, S | 1 |
| Leoni, L | 1 |
| Elliott, G | 1 |
| Chao, Q | 1 |
| Larsson, R | 1 |
| Aleskog, A | 1 |
| Fromer, JL | 1 |
| Sullivan, RD | 1 |
| Ludwig, C | 1 |
| Jandl, H | 2 |
| Franke, A | 2 |
| Kammerer, R | 1 |
| Spormann, H | 2 |
| Kiss, A | 1 |
| Jakó, J | 1 |
| Telek, B | 1 |
| Rák, K | 1 |
| Mey, U | 1 |
| Schaadt, M | 1 |
| Plaumann, L | 1 |
| Diehl, V | 1 |
| Kay, LA | 1 |
| Saunders, PW | 1 |
| Horler, AR | 1 |
| Clark, RH | 1 |
| Dimitrov, NV | 1 |
| Axelson, JA | 1 |
| Charamella, LJ | 1 |
| Lamb, DS | 1 |
| Hudson, GV | 1 |
| Easterling, MJ | 1 |
| MacLennan, KA | 1 |
| Jelliffe, AM | 1 |
| Mead, GM | 1 |
| Macbeth, FR | 1 |
| Williams, CJ | 1 |
| Ryall, RD | 1 |
| Wright, DH | 1 |
| Whitehouse, JM | 2 |
| Kratzer, H | 1 |
| Hehenwarter, W | 1 |
| Denz, H | 1 |
| Bliem, J | 1 |
| Tschurtschenthaler, G | 1 |
| Nitsche, D | 1 |
| Huber, H | 1 |
| Michlmayr, G | 1 |
| Chanda, JJ | 1 |
| Callen, JP | 1 |
| Bolognesi, G | 1 |
| Dumont, J | 1 |
| Thiery, JP | 1 |
| Mazabraud, A | 1 |
| Natali, JC | 1 |
| Trapet, P | 1 |
| Vilcoq, JR | 1 |
| Pedersen-Bjergaard, J | 2 |
| Hansen, MM | 1 |
| Geisler, CH | 1 |
| Nissen, NI | 2 |
| Stacher, A | 1 |
| Heinz, R | 1 |
| Waldner, R | 1 |
| Böhnel, J | 1 |
| Hayhoe, FG | 1 |
| De Weger, RA | 1 |
| Dullens, HF | 1 |
| Den Otter, W | 1 |
| Seewann, HL | 1 |
| Tilz, GP | 1 |
| Becker, H | 1 |
| Lehnert, M | 1 |
| Gerster, JC | 1 |
| Métrailler, A | 1 |
| Saudan, Y | 1 |
| Phillips, DL | 1 |
| Sayed, A | 1 |
| Hove, WV | 1 |
| Vermeulen, A | 1 |
| Knospe, WH | 1 |
| Loeb, V | 1 |
| Watkins, SM | 1 |
| Rassnick, KM | 1 |
| Gould, WJ | 1 |
| Flanders, JA | 1 |
| Bolton-Maggs, PH | 1 |
| Colman, A | 1 |
| Dixon, GR | 1 |
| Myskow, MW | 1 |
| Williams, JG | 1 |
| Donnelly, RJ | 1 |
| Hind, CR | 1 |
| Jensen, MK | 1 |
| Pulczynski, S | 1 |
| Johansen, P | 1 |
| Byrd, JC | 1 |
| Grever, MR | 1 |
| Waselenko, JK | 1 |
| Willis, CR | 1 |
| Park, K | 1 |
| Goodrich, A | 1 |
| Lucas, MA | 1 |
| Shinn, C | 1 |
| Flinn, IW | 1 |
| Vose, JM | 1 |
| Cabanillas, F | 1 |
| O'Brien, S | 1 |
| Dang, N | 1 |
| Drapkin, R | 1 |
| Foss, F | 1 |
| Guclu, A | 4 |
| Ghose, T | 5 |
| Tai, J | 4 |
| Mammen, M | 1 |
| Pasmantier, MW | 1 |
| Coleman, M | 1 |
| Silver, RT | 1 |
| Bennett, JM | 1 |
| Bakemeier, RF | 1 |
| Carbone, PP | 1 |
| Ezdinli, E | 1 |
| Lenhard, RE | 2 |
| Schmidt, CG | 1 |
| Stolzenbach, G | 2 |
| Garbrecht, M | 2 |
| Müllerleile, U | 1 |
| Tisdale, MJ | 3 |
| Phillips, BJ | 2 |
| MacEwen, EG | 1 |
| Patnaik, AK | 1 |
| Wilkins, RJ | 1 |
| Kinlen, LJ | 1 |
| Sheil, AG | 1 |
| Peto, J | 1 |
| Doll, R | 1 |
| Napoli, VM | 1 |
| Nichols, CW | 1 |
| Wright, RE | 1 |
| Calamera, JC | 3 |
| Morgenfeld, MC | 3 |
| Mancini, RE | 3 |
| Vilar, O | 1 |
| Queisser, W | 1 |
| Kalb, M | 1 |
| McLean, A | 1 |
| Woods, RL | 1 |
| Catovsky, D | 2 |
| Farmer, P | 1 |
| Alberts, DS | 1 |
| Chang, SY | 1 |
| Chen, HS | 1 |
| Larcom, BJ | 1 |
| Jones, SE | 3 |
| Blair, AH | 1 |
| Fuchs, R | 1 |
| Lister, TA | 1 |
| Cullen, MH | 1 |
| Beard, ME | 1 |
| Brearley, RL | 1 |
| Wrigley, PF | 1 |
| Stansfeld, AG | 1 |
| Sutcliffe, SB | 1 |
| Malpas, JS | 1 |
| Crowther, D | 1 |
| Houston, KA | 1 |
| O'duffy, JD | 1 |
| McDuffie, FC | 1 |
| Håkansson, L | 1 |
| Könyves, I | 1 |
| Lindberg, LG | 1 |
| Möller, T | 1 |
| Blomgren, H | 1 |
| Jondal, M | 1 |
| Johansson, B | 1 |
| Trepel, F | 1 |
| Schick, P | 1 |
| Norvell, ST | 2 |
| Bodurha, A | 1 |
| Aquino, J | 1 |
| MacDonald, AS | 2 |
| Rosenberg, SA | 5 |
| Kaplan, HS | 3 |
| Thumb, N | 1 |
| Gilbert, HA | 1 |
| Yettra, M | 1 |
| Gordon, J | 1 |
| Kagan, AR | 1 |
| Levy, R | 1 |
| Miller, RA | 1 |
| Harland, CC | 1 |
| Balsitis, M | 1 |
| Millard, LG | 1 |
| Mulligan, SP | 1 |
| Matutes, E | 1 |
| Dearden, C | 1 |
| Anel, A | 1 |
| Halmos, T | 1 |
| Torres, JM | 1 |
| Piñeiro, A | 1 |
| Antonakis, K | 1 |
| Uriel, J | 1 |
| Klener, P | 2 |
| Háber, J | 1 |
| Naito, K | 2 |
| Kubo, K | 1 |
| Akao, Y | 2 |
| Hiraiwa, A | 1 |
| Naoe, T | 1 |
| Yamada, K | 2 |
| Nagura, E | 1 |
| Ohno, R | 1 |
| Nishikawa, M | 2 |
| Tanaka, H | 2 |
| Shirakawa, S | 1 |
| Ono, Y | 1 |
| Ezaki, K | 1 |
| Streuli, RA | 1 |
| Uemura, Y | 1 |
| Matsuoka, N | 1 |
| Ohno, T | 1 |
| Katayama, N | 1 |
| Tomeoku, M | 1 |
| Kobayashi, T | 1 |
| Kita, K | 1 |
| Minami, N | 1 |
| Adair, CG | 1 |
| Bridges, JM | 1 |
| Desai, ZR | 1 |
| Baas, AA | 1 |
| van Herwaarden, CL | 1 |
| Ellis, JT | 1 |
| Peterson, P | 1 |
| Geller, SA | 1 |
| Rappaport, H | 1 |
| Hautekeete, ML | 1 |
| Berneman, ZN | 1 |
| Bieger, R | 1 |
| Stevens, WJ | 1 |
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| Buyssens, N | 1 |
| Peetermans, ME | 1 |
| Michels, SD | 1 |
| McKenna, RW | 1 |
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| Touboul, E | 1 |
| Ghenim, C | 1 |
| Chantelar, JV | 1 |
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| Szpirglas, H | 2 |
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| Wong, P | 1 |
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| Cavallin-Ståhl, E | 1 |
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| Hazleman, B | 1 |
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10 reviews available for chlorambucil and Lymphoma
| Article | Year |
|---|---|
[Therapy of non-Hodgkin's lymphoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cyclophosphamide; Doxorubic | 1984 |
[Clinical relevance of the Kiel classification of non-Hodgkin's lymphomas (author's transl)].
Topics: Adolescent; Adult; Aged; B-Lymphocytes; Child; Chlorambucil; Drug Therapy, Combination; Humans; Lymp | 1980 |
Eradication of murine lymphoma and melanoma cells by chlorambucil-antibody complexes.
Topics: Animals; Antibodies, Neoplasm; Chlorambucil; Cytotoxicity Tests, Immunologic; Drug Combinations; Dru | 1982 |
Chemotherapy of the non-Hodgkin's lymphomas.
Topics: Antineoplastic Agents; Bleomycin; Chlorambucil; Cortisone; Cyclophosphamide; Doxorubicin; Drug Thera | 1976 |
Chlorambucil.
Topics: Animals; Carcinogens; Chlorambucil; Drug Evaluation, Preclinical; Female; Fetus; Humans; Lethal Dose | 1975 |
Current status of treatment of lymphomas.
Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Drug Therapy, Combin | 1975 |
Therapy of lymphoma directed at idiotypes.
Topics: Animals; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Chlorambucil; Clinical Trials as Topic; | 1990 |
The therapy of lymphoma.
Topics: Adrenal Cortex Hormones; Asparaginase; Bone Marrow Diseases; Chlorambucil; Cyclophosphamide; Cytarab | 1969 |
[Current views on drug therapy of tumors].
Topics: Animals; Antineoplastic Agents; Carcinoma, Brown-Pearce; Carcinoma, Ehrlich Tumor; Chlorambucil; Cyc | 1970 |
[Cytostatic chemotherapy of neoplasms in children].
Topics: Adrenal Cortex Hormones; Aminopterin; Antineoplastic Agents; Asparaginase; Child; Child, Preschool; | 1971 |
13 trials available for chlorambucil and Lymphoma
| Article | Year |
|---|---|
Phase III study of chlorambucil versus fludarabine as initial therapy for Waldenstrom's macroglobulinemia and related disorders.
Topics: Administration, Oral; Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Antineoplastic Ag | 2005 |
Clinical trial of prednimustine, Leo-1031 (NSC-134087), in patients with non-Hodgkin lymphomata and chronic lymphocytic leukaemia previously treated with steroids and alkylating agents.
Topics: Adult; Aged; Chlorambucil; Clinical Trials as Topic; Female; Humans; Leukemia, Lymphoid; Lymphoma; M | 1980 |
Chemotherapy in the management of stage III/IV grade 1 non-Hodgkin's lymphomas (Report no 17).
Topics: Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; | 1981 |
Clinical trials with BCNU (NSC-409962) in malignant lymphomas by the Eastern Cooperative Oncology Group.
Topics: Bleomycin; Carmustine; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug T | 1976 |
Comparison of combined and single-agent chemotherapy in non-Hodgkin's lymphoma of favourable histological type.
Topics: Adult; Aged; Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Drug Therapy, Combination; Femal | 1978 |
Clinical trials in the non-Hodgkin's lymphomata at Stanford University experimental design and preliminary results.
Topics: Antineoplastic Agents; Bone Marrow; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Cytara | 1975 |
Therapy of lymphoma directed at idiotypes.
Topics: Animals; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Chlorambucil; Clinical Trials as Topic; | 1990 |
Value of prednimustine in treating non Hodgkin's lymphomas of favourable histological type.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Clinical Trials as Topic; | 1985 |
[Clinical trial of bestrabucil (KM 2210) on hematopoietic malignancies].
Topics: Aged; Chlorambucil; Clinical Trials as Topic; Drug Administration Schedule; Estradiol; Female; Human | 1986 |
Studies of the bone marrow in polycythemia vera and the evolution of myelofibrosis and second hematologic malignancies.
Topics: Acute Disease; Aged; Bloodletting; Bone Marrow; Bone Marrow Cells; Chlorambucil; Combined Modality T | 1986 |
Prednimustine v cyclophosphamide-vincristine-prednisolone in the treatment of non-Hodgkin's lymphoma with favorable histopathology: results of a national cancer care program in Sweden.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophospham | 1986 |
Vinca alkaloids. Experimental and clinical trials.
Topics: Animals; Cell Movement; Chlorambucil; Choriocarcinoma; Female; Hematopoiesis; Hematopoietic Stem Cel | 1974 |
Comparison of chlorambucil and streptonigrin (NSC-45383) in the treatment of malignant lymphomas.
Topics: Antibiotics, Antineoplastic; Bone Marrow; Chlorambucil; Clinical Trials as Topic; Digestive System; | 1969 |
135 other studies available for chlorambucil and Lymphoma
| Article | Year |
|---|---|
Clinical characteristics and outcomes of Mott cell lymphoma in nine miniature dachshunds.
Topics: Animals; Chlorambucil; Dog Diseases; Dogs; Japan; Lymphoma; Retrospective Studies | 2023 |
Clinical characteristics and outcomes of Mott cell lymphoma in nine miniature dachshunds.
Topics: Animals; Chlorambucil; Dog Diseases; Dogs; Japan; Lymphoma; Retrospective Studies | 2023 |
Clinical characteristics and outcomes of Mott cell lymphoma in nine miniature dachshunds.
Topics: Animals; Chlorambucil; Dog Diseases; Dogs; Japan; Lymphoma; Retrospective Studies | 2023 |
Clinical characteristics and outcomes of Mott cell lymphoma in nine miniature dachshunds.
Topics: Animals; Chlorambucil; Dog Diseases; Dogs; Japan; Lymphoma; Retrospective Studies | 2023 |
Clinical characteristics and outcomes of Mott cell lymphoma in nine miniature dachshunds.
Topics: Animals; Chlorambucil; Dog Diseases; Dogs; Japan; Lymphoma; Retrospective Studies | 2023 |
Clinical characteristics and outcomes of Mott cell lymphoma in nine miniature dachshunds.
Topics: Animals; Chlorambucil; Dog Diseases; Dogs; Japan; Lymphoma; Retrospective Studies | 2023 |
Clinical characteristics and outcomes of Mott cell lymphoma in nine miniature dachshunds.
Topics: Animals; Chlorambucil; Dog Diseases; Dogs; Japan; Lymphoma; Retrospective Studies | 2023 |
Clinical characteristics and outcomes of Mott cell lymphoma in nine miniature dachshunds.
Topics: Animals; Chlorambucil; Dog Diseases; Dogs; Japan; Lymphoma; Retrospective Studies | 2023 |
Clinical characteristics and outcomes of Mott cell lymphoma in nine miniature dachshunds.
Topics: Animals; Chlorambucil; Dog Diseases; Dogs; Japan; Lymphoma; Retrospective Studies | 2023 |
Cyclophosphamide rescue therapy for relapsed low-grade alimentary lymphoma after chlorambucil treatment in cats.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cat Diseases; Cats; Chlorambucil; Cyclophos | 2021 |
Suspected chlorambucil-related neurotoxicity with seizures in a dog.
Topics: Animals; Antineoplastic Agents, Alkylating; Chlorambucil; Dog Diseases; Dogs; Lymphoma; Seizures | 2013 |
Chlorambucil and ascorbic acid-mediated anticancer activity and hematological toxicity in Dalton's ascites lymphoma-bearing mice.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Ascites; Ascorbic Acid; Blood Ce | 2014 |
Gallbladder lymphoma in a miniature dachshund.
Topics: Animals; Antineoplastic Agents; Chlorambucil; Dog Diseases; Dogs; Female; Gallbladder Neoplasms; Lym | 2015 |
Myelodysplastic syndrome and acute myeloid leukemia after autotransplantation for lymphoma: a multicenter case-control study.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemoth | 2003 |
Clinical trials of p-(di-2-chloroethylamino)-phenylbutyric acid (CB 1348) in malignant lymphoma.
Topics: Chlorambucil; Lymphoma; Mechlorethamine; Nitrogen Mustard Compounds; Phenylbutyrates | 1955 |
Treatment of malignant lymphoma with chlorambucil (CB 1348, leukeran).
Topics: Chlorambucil; Lymphoma; Mechlorethamine; Nitrogen Mustard Compounds | 1958 |
Clinical evaluation of CB 1348 in malignant lymphoma and related diseases.
Topics: Chlorambucil; Lymphoma; Mechlorethamine; Nitrogen Mustard Compounds | 1958 |
Clinical evaluation of CB 1348 in leukemias and lymphomas.
Topics: Chlorambucil; Leukemia; Lymphoma; Mechlorethamine; Nitrogen Mustard Compounds | 1958 |
[Observations & results in patients with malignant hemolymphatic diseases treated with p-(N,N-di-2-chloroethyl) aminophenylbutyric acid (CB 1348)].
Topics: Chlorambucil; Lymphoma; Mechlorethamine; Neoplasms; Nitrogen Mustard Compounds | 1959 |
Chemotherapy of malignant disease. II. Diseases of lymphoid tissue and bone marrow.
Topics: Adrenal Cortex Hormones; Aged; Bone Marrow; Busulfan; Chlorambucil; Cyclophosphamide; Hodgkin Diseas | 1962 |
THE MALIGNANT LYMPHOMAS.
Topics: Adrenal Cortex Hormones; Chlorambucil; Cyclophosphamide; Hodgkin Disease; Humans; Lymphoma; Lymphoma | 1963 |
[THERAPY OF HEMATODERMIAS].
Topics: Busulfan; Chlorambucil; Cortisone; Cyclophosphamide; Dermatology; Hydrocortisone; Leukemia; Lymphoma | 1963 |
CLINICAL EVALUATION OF URACIL MUSTARD.
Topics: Anemia; Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Female; Hodgkin Disease; Humans; Kidn | 1963 |
THE RETICULOSES.
Topics: Adrenal Cortex Hormones; Chlorambucil; Cyclophosphamide; Dermatitis, Exfoliative; Genetic Diseases, | 1964 |
[CURRENT PRACTICE IN THE TREATMENT OF TUMORS WITH INTRA-ARTERIAL INJECTIONS OF ANTINEOPLASTIC SUBSTANCES].
Topics: Aminopterin; Antineoplastic Agents; Carcinoma; Chemotherapy, Cancer, Regional Perfusion; Chlorambuci | 1963 |
WEEKLY HIGH-DOSAGE GLUCOCORTICOSTEROID TREATMENT OF LYMPHOCYTIC LEUKEMIAS AND LYMPHOMAS.
Topics: Anemia; Anemia, Hemolytic; Betamethasone; Chlorambucil; Dexamethasone; Geriatrics; Humans; Leukemia; | 1964 |
SPINAL-CORD COMPRESSION IN THE MALIGNANT LYMPHOMAS.
Topics: Chlorambucil; Hematopoiesis; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Mercaptopurin | 1964 |
[HISTOPATHOLOGICAL EFFECTS OF ANTINEOPLASTIC AGENTS ON MALIGNANT LYMPHOMA].
Topics: Antineoplastic Agents; Child; Chlorambucil; Cyclophosphamide; Dactinomycin; Geriatrics; Hodgkin Dise | 1964 |
LONG TERM RESULTS ACHIEVED WITH THE USE OF ALKYLATING AGENTS IN MALIGNANT LYMPHOMA AND HODGKIN'S DISEASE.
Topics: Alkylating Agents; Chlorambucil; Cyclophosphamide; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Larg | 1964 |
NONSURGICAL TREATMENT OF PULMONARY CANCER.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adrenal Cortex Hormones; Alkylating Agents; Antineoplastic Agen | 1964 |
THE MANAGEMENT OF LEUKEMIA AND LYMPHOMA.
Topics: Adrenal Cortex Hormones; Busulfan; Chlorambucil; Cortisone; Cyclophosphamide; Hodgkin Disease; Human | 1964 |
CHLORAMBUCIL THERAPY FOR LYMPHOMAS AND CHRONIC LYMPHOCYTIC LEUKEMIA.
Topics: Adrenal Cortex Hormones; Chlorambucil; Drug Synergism; Hodgkin Disease; Leukemia; Leukemia, Lymphocy | 1965 |
RADIATION AND DRUG INDUCED HYALINIZATION OF THE STOMACH.
Topics: Antineoplastic Agents; Child; Chlorambucil; Cyclophosphamide; Drug Therapy; Ganglioneuroma; Gastroin | 1965 |
THE ROLE OF THE PHAGOCYTE IN HOST-PARASITE INTERACTIONS. I. THE PHAGOCYTIC CAPABILITIES OF LEUKOCYTES FROM LYMPHOPROLIFERATIVE DISORDERS.
Topics: Chlorambucil; Drug Therapy; Escherichia coli Infections; Geriatrics; Host-Parasite Interactions; Hum | 1964 |
Treatment of malignant lymphomas and lymphadenoses with leukeran.
Topics: Chlorambucil; Hodgkin Disease; Leukemia; Leukemia, Lymphoid; Lymphoma; Mechlorethamine; Nitrogen Mus | 1959 |
Clinical and haematological observations in lymphoma patients (Hodgkin's disease, Brill-Symmer's disease, lymphogenous leukaemia) treated with N N Di-2-chloroethyl gamma-P-aminophenyl butiric acid (amboclorin).
Topics: Antineoplastic Agents; Chlorambucil; Hodgkin Disease; Humans; Leukemia, Lymphoid; Lymphoma; Lymphoma | 1960 |
[Results obtained with the use of chlorambucil in the treatment of malignant lymphopathies].
Topics: Chlorambucil; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodg | 1961 |
Refractory cold agglutinin-immunohaemolytic anaemia associated to marginal zone lymphoma responding to rituximab.
Topics: Adrenal Cortex Hormones; Aged; Anemia, Hemolytic; Antibodies, Monoclonal; Antibodies, Monoclonal, Mu | 2003 |
Mood alterations in patients treated with chlorambucil.
Topics: Adult; Affect; Aged; Antineoplastic Agents, Alkylating; Central Nervous System; Chlorambucil; Cohort | 2003 |
High dose chlorambucil in the treatment of lymphoid malignancies.
Topics: Antineoplastic Agents, Alkylating; Chlorambucil; Clinical Trials as Topic; Hodgkin Disease; Humans; | 2004 |
R-etodolac (SDX-101) and the related indole-pyran analogues SDX-308 and SDX-309 potentiate the antileukemic activity of standard cytotoxic agents in primary chronic lymphocytic leukaemia cells.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Chlorambu | 2007 |
Continuous arterial infusion chemotherapy for lymphoma and other cutaneous malignant tumors.
Topics: Chlorambucil; Cyclophosphamide; Humans; Injections, Intra-Arterial; Lymphoma; Male; Middle Aged; Ski | 1967 |
[The meaning of maintenance therapy in oncology].
Topics: Breast Neoplasms; Chlorambucil; Hodgkin Disease; Leukemia, Myeloid, Acute; Lymphoma; Methotrexate; N | 1980 |
[Intermediate evaluation of a prospective study of the therapy of malignant non-Hodgkin lymphomas].
Topics: Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Ly | 1981 |
[Experiences in the treatment of non-Hodgkin lymphomas].
Topics: Antineoplastic Agents; Chlorambucil; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Lymphoma | 1981 |
[The effect of therapy on the behavior of T and B-lymphocytes in patients with non-Hodgkin's lymphoma].
Topics: B-Lymphocytes; Chlorambucil; Cyclophosphamide; Humans; Lymphoma; Prednisone; Rosette Formation; T-Ly | 1981 |
Lymphoplasmacytoid lymphoma, associated paraproteinaemia and haemolytic anaemia: a report of 2 cases and review of the literature.
Topics: Anemia, Hemolytic; Chlorambucil; Female; Humans; Immunoglobulin D; Immunoglobulin G; Immunoglobulin | 1983 |
Leukocyte interferon as a possible biological response modifier in lymphoproliferative disorders resistant to standard therapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cell Line; Chlorambucil; Female; Hodgki | 1984 |
Localised grade 2 non-Hodgkin's lymphoma: results of treatment with radiotherapy (BNLI Report No. 24).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined Modality Therapy | 1984 |
Poor prognosis non-Hodgkin's lymphoma in the elderly: clinical presentation and management.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined Modality Therapy; Cyclo | 1984 |
[Results of cytostatic polychemotherapy in non-Hodgkin lymphomas].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Doxorubicin; Drug Th | 1983 |
Necrotizing vasculitis (angiitis) with granulomatosis.
Topics: Azathioprine; Chlorambucil; Cyclophosphamide; Diagnosis, Differential; Granuloma, Lethal Midline; Gr | 1984 |
[Hairy cell leukemia].
Topics: Chlorambucil; Diagnosis, Differential; Heavy Chain Disease; Humans; Leukemia, Hairy Cell; Leukemia, | 1982 |
Acute myeloid leukemia following non-Hodgkin's lymphoma: danger of prolonged use of chlorambucil as maintenance therapy.
Topics: Adult; Aged; Chlorambucil; Female; Humans; Leukemia, Myeloid, Acute; Lymphoma; Middle Aged; Time Fac | 1980 |
[IgD-paraproteinemia in lymphoplasmacytoid immunocytoma].
Topics: Chlorambucil; Cyclophosphamide; Diagnosis, Differential; Humans; Immunoglobulin D; Lymphoma; Male; M | 1982 |
[Malignant lymphoma in a case of disseminated lupus erythematosus treated with cytotoxic agents].
Topics: Adult; Chlorambucil; Female; Humans; Lupus Erythematosus, Systemic; Lymphoma; Melphalan | 1982 |
Radiotherapy in the treatment of localised non-Hodgkin's lymphoma (Report no 16).
Topics: Chlorambucil; Female; Humans; Lymphoma; Male; Middle Aged | 1981 |
Prednisolone plasma levels after oral administration of Prednimustine. Comparison with levels obtained after administration of an equimolar dose of prednisolone.
Topics: Administration, Oral; Adult; Aged; Breast Neoplasms; Chlorambucil; Female; Humans; Lymphoma; Middle | 1981 |
Biweekly chlorambucil treatment of lymphocytic lymphoma.
Topics: Antineoplastic Agents; Chlorambucil; Drug Evaluation; Drug Therapy, Combination; Follow-Up Studies; | 1980 |
Predicting neutropenia after chemotherapy for lymphoma.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cy | 1993 |
Use of a vascular access system for administration of chemotherapeutic agents to a ferret with lymphoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Catheters, Indwelling; Chlora | 1995 |
Mucosa associated lymphoma of the lung.
Topics: Aged; Chlorambucil; Female; Humans; Lung; Lung Neoplasms; Lymphoid Tissue; Lymphoma; Prednisolone | 1993 |
Suspected malignant lymphoma presenting with widespread granulomatous lesions in bones and lymph nodes and responding to combination chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone and Bones; Chlorambucil; Diagnosis, Differentia | 1996 |
Theophylline, pentostatin (Nipent), and chlorambucil: a dose-escalation study targeting intrinsic biologic resistance mechanisms in patients with relapsed lymphoproliferative disorders.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy | 2000 |
Infectious complications of pentostatin therapy.
Topics: Acyclovir; Anti-Infective Agents; Anti-Infective Agents, Urinary; Antibiotics, Antineoplastic; Antib | 2000 |
Binding of chlorambucil with antitumor globulins and its effect on drug and antibody activities.
Topics: Alkylation; Animals; Antibodies, Neoplasm; Biopharmaceutics; Blood Proteins; Cells, Cultured; Chlora | 1976 |
[Chemotherapy in non-Hodgkin's lymphomas (author's transl)].
Topics: Antineoplastic Agents; Bleomycin; Burkitt Lymphoma; Chlorambucil; Cyclophosphamide; Doxorubicin; Dru | 1977 |
[Intermittent chlorambucil-prednisone therapy in low malignancy non-Hodgkin lymphoma and cyclic induction chemotherapy with COP-bleomycin of severe non-Hodgkin lymphoma according to the Kiel classification].
Topics: Bleomycin; Chlorambucil; Drug Therapy, Combination; Lymphoma; Neoplasm Invasiveness; Neoplasm Stagin | 1978 |
Clinicopathological conference. Two cases of drug-induced disease. Demonstration at the Royal College of Physicians of London.
Topics: Adult; Aged; Bronchiectasis; Chlorambucil; Cyclophosphamide; Demeclocycline; Diabetes Insipidus; Fem | 1978 |
Adenosine 3',5'-monophosphate phosphodiesterase activity in experimental animal tumours which are either sensitive or resistant to bifunctional alkylating agents.
Topics: Alkylating Agents; Animals; Carcinoma 256, Walker; Cells, Cultured; Chlorambucil; Cyclic AMP; Drug R | 1975 |
The effect of alkylating agents on the activity of adenosine 3',5'-monophosphate-dependent protein kinase in Walker carcinoma cells.
Topics: Alkylating Agents; Animals; Aziridines; Bucladesine; Carcinoma 256, Walker; Cell Line; Cells, Cultur | 1976 |
Diagnosis and treatment of canine hematopoietic neoplasms.
Topics: Animals; Chlorambucil; Dog Diseases; Dogs; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma | 1977 |
Collaborative United Kingdom-Australasian study of cancer in patients treated with immunosuppressive drugs.
Topics: Adolescent; Adult; Aged; Australia; Azathioprine; Chlorambucil; Cyclophosphamide; Female; Follow-Up | 1979 |
Malignant lymphoma of thenasopharyns in waldenström's macroglobulinemia: report of a case with severe epistaxis.
Topics: Chlorambucil; Cobalt Radioisotopes; Epistaxis; Female; Humans; Lymphoma; Middle Aged; Nasopharyngeal | 1977 |
Biochemical changes of the human semen produced by chlorambucil, testosterone propionate and human chorionic gonadotropin administration.
Topics: Adolescent; Adult; Cell Count; Chlorambucil; Chorionic Gonadotropin; Citrates; Fructose; Humans; Lym | 1979 |
Intermittent combination chemotherapy with chlorambucil and prednisone of low-grade malignant non-Hodgkin's lymphomas according to the Kiel classification.
Topics: Adult; Aged; Bone Marrow; Chlorambucil; Drug Administration Schedule; Drug Therapy, Combination; Fem | 1979 |
[Secondary carcinoma: a complication of cytostatic therapy?].
Topics: Antineoplastic Agents; Breast Neoplasms; Carcinogens; Chlorambucil; Female; Humans; Immunosuppressio | 1979 |
Pharmacokinetics and metabolism of chlorambucil in patients with malignant disease.
Topics: Administration, Oral; Chlorambucil; Female; Humans; Injections, Intravenous; Kinetics; Leukemia, Lym | 1979 |
Pharmacokinetics and metabolism of chlorambucil in man: a preliminary report.
Topics: Administration, Oral; Adult; Aged; Chlorambucil; Female; Humans; Intestinal Absorption; Leukemia, Ly | 1979 |
Tumor inhibition by chlorambucil covalently linked to antitumor globulin.
Topics: Animals; Antibodies, Neoplasm; Antibody Formation; Antigens, Neoplasm; Chlorambucil; Female; Lymphom | 1979 |
[Therapy of malignant non-Hodgkin's lymphoma].
Topics: Brain Neoplasms; Chlorambucil; Cyclophosphamide; Humans; Injections, Spinal; Lymphoma; Methotrexate; | 1979 |
Behçet's disease associated with a lymphoproliferative disorder, mixed cryoglobulinemia, and an immune complex mediated vasculitis.
Topics: Antigen-Antibody Complex; Behcet Syndrome; Chlorambucil; Cryoglobulins; Female; Follow-Up Studies; H | 1978 |
Continuous treatment of non-Hodgkin's malignant lymphoma with prednimustine (Leo 1031).
Topics: Adult; Aged; Chlorambucil; Female; Humans; Leukopenia; Lymphoma; Male; Middle Aged; Prednisolone; Th | 1978 |
In vivo and in vitro selection of mitogen responsive lymphocytes in patients with chronic lymphocytic leukemia.
Topics: Adult; Aged; Cell Separation; Chlorambucil; Concanavalin A; Cyclophosphamide; Female; Humans; Immuno | 1976 |
[Proliferation and growth of lymphatic cell population in malignant lymphomas].
Topics: Chlorambucil; Cytogenetics; Hematopoiesis; Hodgkin Disease; Humans; Leukemia, Lymphoid; Lymphocytes; | 1976 |
Antibodies as carriers of radionuclides and cytotoxic drugs in the treatment and diagnosis of cancer.
Topics: Animals; Antibodies, Neoplasm; Antineoplastic Agents; Chlorambucil; Female; Humans; Immunoelectropho | 1976 |
Suppression of an AKR lymphoma by antibody and chlorambucil.
Topics: Animals; Antibodies, Neoplasm; Chlorambucil; Female; Fluorescent Antibody Technique; Immunization, P | 1975 |
The Hamman-Rich syndrome following treatment of lymphoma with chlorambucil.
Topics: Aged; Chlorambucil; Humans; Lymphoma; Male; Pulmonary Fibrosis | 1975 |
[Side effects in immunosuppressive therapy].
Topics: Alopecia; Amenorrhea; Anemia; Azathioprine; Bacterial Infections; Chlorambucil; Female; Humans; Immu | 1975 |
On long-term survivals in non-Hodgkin's lymphoma with 'gentle' treatment.
Topics: Adult; Aged; Child; Chlorambucil; Female; Follow-Up Studies; Humans; Lymph Nodes; Lymphoma; Male; Mi | 1976 |
Sézary-type cutaneous T-cell leukaemia. Response to Winkelmann regimen.
Topics: Adult; Chlorambucil; Female; Humans; Leukemia, T-Cell; Lymphoma; Prednisolone; Prognosis; PUVA Thera | 1990 |
Splenic lymphoma with villous lymphocytes: natural history and response to therapy in 50 cases.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combin | 1991 |
Cytotoxicity of chlorambucil and chlorambucil-fatty acid conjugates against human lymphomas and normal human peripheral blood lymphocytes.
Topics: Arachidonic Acids; Cell Division; Cells, Cultured; Chlorambucil; Docosahexaenoic Acids; Dose-Respons | 1990 |
[Clinical trial of bestrabucil (KM 2210) in hematopoietic malignancies].
Topics: Aged; Chlorambucil; Deltaretrovirus Infections; Estradiol; Female; Humans; Lymphoma; Male; Middle Ag | 1986 |
[Early phase II trial of bestrabucil in hematological malignancies].
Topics: Adult; Aged; Chlorambucil; Drug Administration Schedule; Drug Evaluation; Estradiol; Female; Humans; | 1986 |
Antitumor imidazotetrazines--XV. Role of guanine O6 alkylation in the mechanism of cytotoxicity of imidazotetrazinones.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line; Chlorambucil; Colonic Neoplasms; Dacarbaz | 1987 |
[Chronic lymphatic leukemia].
Topics: Bone Marrow; Chlorambucil; Humans; Leukemia, Lymphoid; Leukocyte Count; Lymphocytosis; Lymphoma; Mal | 1986 |
Can food affect the bioavailability of chlorambucil in patients with haematological malignancies?
Topics: Adult; Aged; Biological Availability; Chlorambucil; Chromatography, High Pressure Liquid; Fasting; F | 1986 |
Primary non-Hodgkin lymphoma of the lung.
Topics: Chlorambucil; Combined Modality Therapy; Humans; Lung Neoplasms; Lymphoma; Male; Middle Aged; Radiog | 1986 |
Purpura fulminans in pneumococcal sepsis.
Topics: Acute Kidney Injury; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Fema | 1986 |
Therapy-related acute myeloid leukemia and myelodysplastic syndrome: a clinical and morphologic study of 65 cases.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Behcet Syndrome; Bone Marrow; Carcinoma; Child; Chil | 1985 |
[Non-Hodgkin lymphomas of the head and neck, stages I and II. Apropos 35 cases].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined Modality Therapy | 1985 |
A histologically occult lymphoma revealed by electron microscopy.
Topics: Aged; Biopsy; Chlorambucil; Demeclocycline; Diagnosis, Differential; Humans; Lymphoma; Male; Microsc | 1985 |
Prednimustine in refractory non-Hodgkin's lymphoma: a phase II study of the Northern California Oncology Group.
Topics: Adult; Aged; Blood; Chlorambucil; Dose-Response Relationship, Drug; Drug Evaluation; Humans; Lymphom | 1986 |
Incidence of neoplasms in patients with rheumatoid arthritis exposed to different treatment regimens.
Topics: Arthritis, Rheumatoid; Azathioprine; Chlorambucil; Cyclophosphamide; Cystitis; Humans; Immunosuppres | 1985 |
Risk of acute nonlymphocytic leukemia and preleukemia in patients treated with cyclophosphamide for non-Hodgkin's lymphomas. Comparison with results obtained in patients treated for Hodgkin's disease and ovarian carcinoma with other alkylating agents.
Topics: Acute Disease; Adolescent; Adult; Aged; Alkylating Agents; Antineoplastic Combined Chemotherapy Prot | 1985 |
Chlorambucil-induced myoclonic seizures in an adult.
Topics: Aged; Chlorambucil; Female; Humans; Lymphoma; Myoclonus | 1985 |
C1 esterase inhibitor as a possible tumour marker in malignant lymphoma.
Topics: Angioedema; Chlorambucil; Chlorpheniramine; Complement C1 Inactivator Proteins; Humans; Lymphoma; Ma | 1985 |
[Results with the cytostatic agent bleomycin in tumour therapy (author's transl)].
Topics: Adult; Aged; Bleomycin; Bronchial Neoplasms; Carcinoma, Squamous Cell; Chlorambucil; Doxorubicin; Dr | 1973 |
Antibodies as carriers of anticancer agents.
Topics: Animals; Antibodies, Neoplasm; Antigen-Antibody Reactions; Antigens, Neoplasm; Antineoplastic Agents | 1974 |
Protection of mice against syngeneic lymphomata: II. Collaboration between drugs and antibodies.
Topics: Animals; Antibodies, Neoplasm; Antineoplastic Agents; Carcinoembryonic Antigen; Cell Line; Chlorambu | 1974 |
[Sjögren's syndrome with pseudolymphoma].
Topics: Biopsy; Chlorambucil; Diagnosis, Differential; Female; Hodgkin Disease; Humans; Lymph Nodes; Lymphat | 1974 |
Treatment of Sezary syndrome.
Topics: Chlorambucil; Cyclophosphamide; Dermatitis, Exfoliative; Humans; Keratoderma, Palmoplantar; Lymphati | 1974 |
[Rheumatoid polyarthritis and chronic lymphoid leukemia. Studies of 7 cases of association of these 2 diseases].
Topics: Adult; Age Factors; Aged; Animals; Antibodies; Arthritis, Rheumatoid; Autoimmune Diseases; Chlorambu | 1969 |
[Waldenström's macroglobulinemia with pleuropulmonary, orbital and subcutaneous localisation. Favorable effect of chlorambucil].
Topics: Aged; Biopsy; Bronchial Diseases; Chlorambucil; Humans; Immunoelectrophoresis; Lung; Lung Diseases; | 1972 |
[Cancer and immunosuppressive treatment. Apropos of 2 cases].
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Brain Neoplasms; Carcinoma, Squamous Cell; Chlorambucil; | 1974 |
The combined effect of drugs and tumor-specific antibodies in protection against a mouse lymphoma.
Topics: Animals; Antibodies, Neoplasm; Chlorambucil; Cytarabine; Immune Sera; Immunotherapy; Lymphoma; Melph | 1974 |
[Letter: Progredient liver cirrhosis in chronic lymphatic leukemia].
Topics: Chlorambucil; Diabetes Complications; Hepatitis B; Humans; Leukemia, Lymphoid; Liver Cirrhosis; Lymp | 1974 |
[Gougerot-Sjorgen's syndrome and lymphoid hemopathies].
Topics: Aged; Biopsy; Chlorambucil; Female; Humans; Leukemia, Lymphoid; Lymphography; Lymphoma; Parotid Glan | 1972 |
In vivo and in vitro effects of tumour specific antibodies with chlorambucil.
Topics: Absorption; Animals; Antibodies, Neoplasm; Antilymphocyte Serum; Binding Sites; Chlorambucil; Cultur | 1973 |
Non-Hodgkin's lymphomas. II. Single agent chemotherapy.
Topics: Alkylating Agents; Chlorambucil; Cyclophosphamide; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse | 1972 |
Immunochemotherapy of cancer with chlorambucil-carrying antibody.
Topics: Aged; Animals; Antibodies; Cell Membrane; Chlorambucil; Fluorescent Antibody Technique; Goats; Human | 1972 |
Treatment of Hodgkin's disease and other malignant lymphomas.
Topics: Alkylating Agents; Antineoplastic Agents; Carmustine; Chlorambucil; Cyclohexanes; Cyclophosphamide; | 1973 |
Survival of hematopoietic and lymphoma colony-forming cells in vivo following the administration of a variety of alkylating agents.
Topics: Alkylating Agents; Animals; Cell Line; Cell Survival; Chlorambucil; Clone Cells; Cyclophosphamide; F | 1972 |
Recovery of spermatogenesis in patients with lymphoma after treatment with chlorambucil.
Topics: Adult; Cell Movement; Chlorambucil; Humans; Infertility, Male; Lymphoma; Male; Spermatogenesis; Sper | 1973 |
Chemotherapy of the lymphomas.
Topics: Adult; Burkitt Lymphoma; Child; Chlorambucil; Cyclophosphamide; Doxorubicin; Drug Therapy, Combinati | 1974 |
Contribution of lymphangiography to our understanding of lymphoma.
Topics: Chlorambucil; Hodgkin Disease; Humans; Lymphography; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymp | 1968 |
Effect of chlorambucil on spermatogenesis in the human with malignant lymphoma.
Topics: Adolescent; Adult; Biopsy; Chlorambucil; Hodgkin Disease; Humans; Infertility, Male; Lymphoma; Lymph | 1970 |
Alkylating agents and human spermatogenesis.
Topics: Adolescent; Adult; Alkylating Agents; Chlorambucil; Cyclophosphamide; Hodgkin Disease; Humans; Lymph | 1971 |
Enhanced growth of transplanted tumours after treatment with cytotoxic agents.
Topics: Animals; Antineoplastic Agents; Busulfan; Chlorambucil; Ethers, Cyclic; Lymphoma; Mannomustine; Meth | 1968 |
[Results and current biological bases of therapy of malignant hemoreticulopathies].
Topics: Antineoplastic Agents; Chlorambucil; Cortisone; Cyclophosphamide; Humans; Hydrazines; Leukemia; Lymp | 1971 |
Non-Hodgkin's lymphomas. I. Bone marrow involvement.
Topics: Biopsy; Blood Platelets; Bone Marrow; Bone Marrow Examination; Chlorambucil; Cyclophosphamide; Hemat | 1972 |
Management of chylothorax secondary to lymphoma.
Topics: Abdominal Neoplasms; Chlorambucil; Chylothorax; Cyclophosphamide; Drainage; Humans; Lymphoma; Male; | 1972 |
Chlorambucil-carrying antibody.
Topics: Animals; Antibodies, Neoplasm; Chlorambucil; Humans; Lymphoma; Melanoma; Mice; Neoplasms, Experiment | 1972 |
Leukemia and lymphoma.
Topics: Antineoplastic Agents; BCG Vaccine; Burkitt Lymphoma; Busulfan; Chlorambucil; Cyclophosphamide; Cyta | 1970 |
Recent advances in chemotherapy of lymphoma.
Topics: Alkylating Agents; Chlorambucil; Cyclophosphamide; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Larg | 1967 |
[Chemotherapy of malignant lymphomas].
Topics: Adrenal Cortex Hormones; Amines; Chlorambucil; Cyclophosphamide; Hodgkin Disease; Humans; Hydrazines | 1970 |
The indication for chemotherapy in the lymphomas.
Topics: Antineoplastic Agents; Benzoates; Burkitt Lymphoma; Chlorambucil; Cyclophosphamide; Hodgkin Disease; | 1970 |
[A further case of alpha chain disease in a Eurasian].
Topics: Adrenal Cortex Hormones; Adult; Age Factors; Blood Protein Disorders; Chlorambucil; Humans; Immunity | 1970 |
Chemotherapy of Hodgkin's disease, lymphoma, and leukemia.
Topics: Adult; Antineoplastic Agents; Busulfan; Chlorambucil; Hodgkin Disease; Humans; Leukemia; Lymphoma; M | 1968 |
Chemotherapy of malignant lymphoma in dogs and cats.
Topics: Animals; Blood Cells; Cat Diseases; Cats; Chlorambucil; Cyclophosphamide; Dog Diseases; Dogs; Female | 1968 |
[Treatment of malignant lymphomas: its repercussion in the genital region].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Chlorambucil; Cyclophosphamide; Drug-Related Side Effect | 1968 |
Kaposi's sarcoma and coexistent giant follicular lymphoblastoma.
Topics: Chlorambucil; Humans; Lymphoma; Male; Middle Aged; Nitrogen Mustard Compounds; Sarcoma, Kaposi | 1966 |