chlorambucil has been researched along with Lymphoma, Non-Hodgkin in 153 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Lymphoma, Non-Hodgkin: Any of a group of malignant tumors of lymphoid tissue that differ from HODGKIN DISEASE, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumors is the absence of giant REED-STERNBERG CELLS, a characteristic of Hodgkin's disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Anecdotal reports of chlorambucil-induced seizures have sporadically appeared, mainly in the nononcologic literature." | 8.79 | Chlorambucil-induced seizures. ( Cooper, DL; Khan, KK; Salloum, E, 1997) |
| "We investigated the toxicity and efficacy of the chimaeric anti-CD20 antibody rituximab in combination with standard-dose chlorambucil in newly diagnosed and relapsed/refractory indolent B-cell lymphoma patients." | 5.10 | Chlorambucil in combination with induction and maintenance rituximab is feasible and active in indolent non-Hodgkin's lymphoma. ( Bertolini, F; Calleri, A; Cavalli, F; Laszlo, D; Mancuso, P; Martinelli, G; Pastano, R; Santoro, P; Vanazzi, A; Zucca, E, 2003) |
| "Anecdotal reports of chlorambucil-induced seizures have sporadically appeared, mainly in the nononcologic literature." | 4.79 | Chlorambucil-induced seizures. ( Cooper, DL; Khan, KK; Salloum, E, 1997) |
| " The mean bioavailability was 14% for chlorambucil, 21% for phenylacetic acid mustard, and 22% for prednisolone, when given as prednimustine, compared to the administration of free compounds in stoichiometrically equivalent doses." | 2.67 | Comparative pharmacokinetics of chlorambucil and prednimustine after oral administration. ( Loos, U; Malek, M; Musch, E; Riedel, E, 1991) |
| "In the chronic lymphocytic leukemia group, 3/4 have had benefit." | 2.64 | Treatment of chronic lymphocytic leukemia and lymphosarcoma with a new chlorambucil ester of prednisolone (Leo 1031) (NSC-134087). ( Aungst, CW; Mittelman, A; Murphy, GP, 1975) |
| "Histopathological subtypes consist of Burkitt's lymphoma (BL) in 32 (43." | 1.48 | Demographics and Outome in Paediatric Non-Hodgkin Lymphoma: Single Centre Experience at The Children Hospital Lahore, Pakistan. ( Anwar, S; Faizan, M; Khan, S, 2018) |
| "Patients with intestinal small cell lymphosarcoma can present identical clinical signs, and differentiating between these two conditions can be a challenge." | 1.39 | Feline small cell lymphosarcoma versus inflammatory bowel disease: treatment and prognosis. ( Al-Ghazlat, S; de Rezende, CE, 2013) |
| "At the same time, she developed xanthomatous patches on the face, neck, and shoulders (Fig." | 1.33 | Necrobiotic xanthogranuloma associated with paraproteinemia and non-Hodgkin's lymphoma developing into chronic lymphocytic leukemia: the first case reported in the literature and review of the literature. ( Oumeish, I; Oumeish, OY; Salman, T; Sharaiha, A; Tarawneh, M, 2006) |
| " Pharmacokinetic studies suggest decreased bioavailability with successive cycles, probably due to accelerated metabolism." | 1.32 | High dose chlorambucil in the treatment of lymphoid malignancies. ( Nicolle, A; Proctor, SJ; Summerfield, GP, 2004) |
| "Chlorambucil has been used for many years for the treatment of low-grade B-cell lymphoproliferative disorders, including chronic lymphocytic leukaemia and low-grade non-Hodgkin's lymphoma." | 1.31 | High-dose chlorambucil for the treatment of chronic lymphocytic leukaemia and low-grade non-Hodgkin's lymphoma. ( Mounter, PJ; Proctor, SJ; Summerfield, GP; Taylor, PR, 2002) |
| " The dosage of chlorambucil was decreased with a subsequent decrease in symptomatology." | 1.30 | Myoclonus due to chlorambucil in two adults with lymphoma. ( Bayliff, CD; Kovacs, MJ; Wyllie, AR, 1997) |
| "We describe two cases of interstitial lung disease in patients with non-Hodgkin's lymphoma who were treated with combination chemotherapy including mitozantrone." | 1.30 | Interstitial pneumonitis following mitozantrone, chlorambucil and prednisolone (MCP) chemotherapy. ( Johnson, S; Nicholson, AG; Rule, S; Stone, R; Tighe, M; Tomlinson, J, 1999) |
| "One response, however, did relate that diffuse histiocytic lymphoma developed in three of 141 patients receiving prolonged chlorambucil therapy for polycythemia vera." | 1.26 | Lymphoma in primary chronic cold hemagglutinin disease treated with chlorambucil. ( Chaplin, H, 1982) |
| "Low-grade malignant lymphomas are treated best with conventional doses of an alkylating agent." | 1.26 | [Chemotherapy in non-Hodgkin's lymphomas (author's transl)]. ( Schmidt, CG, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 88 (57.52) | 18.7374 |
| 1990's | 37 (24.18) | 18.2507 |
| 2000's | 25 (16.34) | 29.6817 |
| 2010's | 3 (1.96) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Faizan, M | 1 |
| Anwar, S | 1 |
| Khan, S | 1 |
| de Rezende, CE | 1 |
| Al-Ghazlat, S | 1 |
| Martinelli, G | 3 |
| Montoro, J | 1 |
| Vanazzi, A | 2 |
| Andreola, G | 2 |
| Liptrott, S | 1 |
| Radice, D | 1 |
| Negri, M | 1 |
| Preda, L | 1 |
| Pruneri, G | 1 |
| Laszlo, D | 3 |
| Jonathan, F | 1 |
| Leleu, X | 1 |
| Soumerai, J | 1 |
| Roccaro, A | 1 |
| Hatjiharissi, E | 1 |
| Hunter, ZR | 1 |
| Manning, R | 1 |
| Ciccarelli, BT | 1 |
| Sacco, A | 1 |
| Ioakimidis, L | 1 |
| Adamia, S | 1 |
| Moreau, AS | 1 |
| Patterson, CJ | 1 |
| Ghobrial, IM | 1 |
| Treon, SP | 1 |
| Schmitt, B | 1 |
| Wendtner, CM | 1 |
| Bergmann, M | 1 |
| Busch, R | 1 |
| Franke, A | 2 |
| Pasold, R | 2 |
| Schlag, R | 1 |
| Hopfinger, G | 1 |
| Hiddemann, W | 1 |
| Emmerich, B | 1 |
| Hallek, M | 1 |
| Davies, JH | 1 |
| Whitaker, SJ | 1 |
| Herold, M | 1 |
| Dölken, G | 1 |
| Fiedler, F | 1 |
| Freund, M | 1 |
| Helbig, W | 1 |
| Ardeshna, KM | 1 |
| Smith, P | 1 |
| Norton, A | 1 |
| Hancock, BW | 1 |
| Hoskin, PJ | 1 |
| MacLennan, KA | 1 |
| Marcus, RE | 1 |
| Jelliffe, A | 1 |
| Vaughan, G | 1 |
| Linch, DC | 1 |
| PITNEY, WR | 1 |
| MOLANDER, DW | 1 |
| WERDEGAR, D | 1 |
| ADLER, H | 1 |
| WATLINGTON, C | 1 |
| WILLIAMS, HM | 1 |
| FEIWEL, M | 1 |
| MUNRO, DD | 1 |
| VIGI, F | 1 |
| BURNINGHAM, RA | 1 |
| RESTREPO, A | 1 |
| PUGH, RP | 1 |
| BROWN, EB | 1 |
| SCHLOSSMAN, SF | 1 |
| KHURI, PD | 1 |
| LESSNER, HE | 1 |
| HARRINGTON, WJ | 1 |
| DIAMANDOPOULOS, GT | 1 |
| SMITH, EB | 1 |
| IRVINE, RA | 1 |
| ROBERTSON, WB | 1 |
| TANIDA, T | 1 |
| PAPAC, RJ | 1 |
| WOOD, DA | 2 |
| BROUET, G | 1 |
| MARCHE, J | 1 |
| CHRETIEN, J | 1 |
| HUGUS, FC | 1 |
| KARNOFSKY, DA | 1 |
| SANDBERG, AA | 1 |
| ISHIHARA, T | 1 |
| KIKUCHI, Y | 1 |
| CROSSWHITE, LH | 1 |
| HUTCHISON, JL | 1 |
| EZDINLI, EZ | 3 |
| STUTZMAN, L | 3 |
| WANEBO, HJ | 1 |
| CLARKSON, BD | 1 |
| PRADHAN, SN | 1 |
| WEST, WL | 1 |
| RABENKO, J | 1 |
| Bertolini, F | 2 |
| Pastano, R | 1 |
| Mancuso, P | 2 |
| Calleri, A | 1 |
| Santoro, P | 1 |
| Cavalli, F | 3 |
| Zucca, E | 3 |
| Seriakov, AP | 1 |
| Ushakov, II | 1 |
| Ardashev, VN | 1 |
| Mazurov, VI | 1 |
| Korotkiĭ, AN | 1 |
| Froehner, M | 1 |
| Haase, M | 1 |
| Hakenberg, OW | 1 |
| Wirth, MP | 1 |
| Nicolle, A | 1 |
| Proctor, SJ | 7 |
| Summerfield, GP | 3 |
| Wöhrer, S | 1 |
| Raderer, M | 1 |
| Kaufmann, H | 1 |
| Hejna, M | 1 |
| Chott, A | 1 |
| Zielinski, CC | 1 |
| Drach, J | 1 |
| Goor, KM | 1 |
| Schaafsma, MR | 1 |
| Huijgens, PC | 1 |
| van Agthoven, M | 1 |
| Willis, CR | 1 |
| Goodrich, A | 1 |
| Park, K | 1 |
| Waselenko, JK | 1 |
| Lucas, M | 1 |
| Reese, A | 1 |
| Diehl, LF | 1 |
| Grever, MR | 1 |
| Byrd, JC | 1 |
| Flinn, IW | 1 |
| Oumeish, OY | 1 |
| Oumeish, I | 1 |
| Tarawneh, M | 1 |
| Salman, T | 1 |
| Sharaiha, A | 1 |
| Bassi, S | 1 |
| Agazzi, A | 1 |
| Antoniotti, P | 1 |
| Balzano, R | 1 |
| Lau, CP | 1 |
| Ma, B | 1 |
| Chan, AT | 1 |
| Taylor, PR | 5 |
| White, JM | 2 |
| Prescott, RJ | 3 |
| Angus, B | 4 |
| Galloway, MJ | 3 |
| Jackson, GH | 3 |
| Lessells, AM | 2 |
| Lucraft, HH | 4 |
| Rigacci, L | 1 |
| Nassi, L | 1 |
| Puccioni, M | 1 |
| Mappa, S | 1 |
| Polito, E | 1 |
| Dal Pozzo, S | 1 |
| Alterini, R | 1 |
| Carrai, V | 1 |
| Puccini, B | 1 |
| Bosi, A | 1 |
| Shohat, B | 1 |
| Gitter, S | 1 |
| Lavie, D | 1 |
| Han, T | 4 |
| Sokal, JE | 3 |
| Silber, R | 1 |
| Ellison, GW | 1 |
| Myers, LW | 1 |
| Geerts, ML | 1 |
| Hamers, J | 1 |
| Schwarze, EW | 1 |
| Kint, A | 1 |
| Roels, H | 1 |
| Lennert, K | 1 |
| Chaplin, H | 1 |
| Ideström, K | 1 |
| Kimby, E | 2 |
| Björkholm, M | 2 |
| Mellstedt, H | 1 |
| Engstedt, L | 1 |
| Gahrton, G | 2 |
| Johansson, B | 2 |
| Killander, D | 1 |
| Robérts, KH | 1 |
| Stalfelt, AM | 1 |
| Udén, AM | 1 |
| Wadman, B | 1 |
| Wählby, S | 2 |
| Glimelius, B | 1 |
| Hagberg, H | 1 |
| Johansson, H | 1 |
| Juliusson, G | 1 |
| Järnmark, M | 1 |
| Löfvenberg, E | 1 |
| Lennard, AL | 2 |
| Carey, P | 1 |
| Lucraft, H | 1 |
| Evans, RG | 2 |
| Economopoulos, T | 1 |
| Stathakis, N | 1 |
| Constantinidou, M | 1 |
| Papageorgiou, E | 1 |
| Anastassiou, C | 1 |
| Raptis, S | 1 |
| Wells, P | 1 |
| Wotherspoon, A | 1 |
| Burnet, NG | 1 |
| Tobias, JS | 1 |
| Iaffaioli, RV | 1 |
| Frasci, G | 1 |
| Palmieri, G | 1 |
| Tagliaferri, P | 1 |
| Montesarchio, V | 1 |
| Pagliarulo, C | 1 |
| Tortoriello, A | 1 |
| Facchini, G | 1 |
| Matano, E | 1 |
| Lauria, R | 1 |
| Bernard, T | 1 |
| Johnson, SA | 1 |
| Prentice, AG | 1 |
| Jones, L | 2 |
| Phillips, MJ | 1 |
| Newland, AC | 2 |
| Kelsey, SM | 2 |
| Hudson, GV | 1 |
| Jelliffe, AM | 1 |
| Cowley, NC | 1 |
| Neill, SM | 1 |
| Staughton, RC | 1 |
| Fontana, S | 1 |
| Roggero, E | 2 |
| Pedrinis, E | 2 |
| Pampallona, S | 1 |
| Tefferi, A | 1 |
| Witzig, TE | 1 |
| Reid, JM | 1 |
| Li, CY | 1 |
| Ames, MM | 1 |
| Molica, S | 1 |
| Tucci, L | 1 |
| Levato, D | 1 |
| Levato, L | 1 |
| Manfredi, L | 1 |
| Haak, HL | 1 |
| Gerrits, WB | 1 |
| Wijermans, PW | 1 |
| Kerkhofs, H | 1 |
| Joseph, G | 1 |
| Hadley, T | 1 |
| Djulbegovic, B | 1 |
| Hamm, J | 1 |
| Seeger, J | 1 |
| Blumenreich, M | 1 |
| Woodcock, T | 1 |
| Avilés, A | 1 |
| Talavera, A | 1 |
| Guzmán, R | 1 |
| Cuadra, I | 1 |
| Vail, DM | 1 |
| Kisseberth, WC | 1 |
| Obradovich, JE | 1 |
| Moore, FM | 1 |
| London, CA | 1 |
| MacEwen, EG | 2 |
| Ritter, MA | 1 |
| Korobko, VB | 1 |
| Chernyĭ, VA | 1 |
| Valetskiĭ, VL | 1 |
| Rozumiĭ, DA | 1 |
| Gunina, LM | 1 |
| Falk, S | 1 |
| Walther, F | 1 |
| Denk, R | 1 |
| Wyllie, AR | 1 |
| Bayliff, CD | 1 |
| Kovacs, MJ | 1 |
| Salloum, E | 1 |
| Khan, KK | 1 |
| Cooper, DL | 1 |
| Gressin, R | 1 |
| Legouffe, E | 1 |
| Leroux, D | 1 |
| Jacob, MC | 1 |
| Swiercz, P | 1 |
| Peoch, M | 1 |
| Capdevilla, V | 1 |
| Rossi, JF | 1 |
| Thyss, A | 1 |
| Sotto, JJ | 1 |
| Cameron, DA | 1 |
| Leonard, RC | 4 |
| Cook, MK | 1 |
| Dawes, PJ | 1 |
| Dawson, AA | 2 |
| Harris, AL | 1 |
| Heppleston, A | 1 |
| Horne, CH | 1 |
| Krajewski, AS | 1 |
| MacGillivray, JB | 1 |
| Mackie, MJ | 1 |
| Parker, AC | 2 |
| Roberts, JT | 1 |
| Thompson, WD | 1 |
| Piatelli, A | 1 |
| Croce, A | 1 |
| Tete, S | 1 |
| Artese, L | 1 |
| Pinotti, G | 1 |
| Pascarella, A | 1 |
| Bertoni, F | 1 |
| Savio, A | 1 |
| Savio, E | 1 |
| Capella, C | 1 |
| Saletti, P | 1 |
| Morandi, E | 1 |
| Santandrea, G | 1 |
| Khan, MA | 1 |
| Hellawell, GO | 1 |
| Nargund, VH | 1 |
| Shammas, FV | 1 |
| Heikkilä, R | 1 |
| Sternberg, AJ | 1 |
| Matutes, E | 1 |
| Killick, S | 1 |
| Wotherspoon, AC | 1 |
| Catovsky, D | 1 |
| Gandarillas, MA | 1 |
| Conde, E | 1 |
| Mazorra, F | 1 |
| Cuadrado, MA | 1 |
| Baro, J | 1 |
| Garijo, J | 1 |
| Recio, M | 1 |
| Richard, C | 1 |
| Iriondo, A | 1 |
| Zubizarreta, A | 1 |
| Enzenauer, RW | 1 |
| Brozetti, JJ | 1 |
| Dragoo, RA | 1 |
| Tomlinson, J | 1 |
| Tighe, M | 1 |
| Johnson, S | 1 |
| Stone, R | 1 |
| Nicholson, AG | 1 |
| Rule, S | 1 |
| Várkonyi, J | 1 |
| Zalatnai, A | 1 |
| Timár, J | 1 |
| Matolcsi, A | 1 |
| Falus, A | 1 |
| Bencsáth, M | 1 |
| László, V | 1 |
| Pócsik, E | 1 |
| Kotlán, B | 1 |
| Császár, A | 1 |
| Soukop, M | 1 |
| Tinegate, H | 1 |
| Shamash, J | 1 |
| Walewski, J | 1 |
| Apostolidis, J | 1 |
| Wilson, AM | 1 |
| Foran, JM | 1 |
| Gupta, RK | 1 |
| Rohatiner, AZ | 2 |
| Lister, TA | 2 |
| Jourdan, E | 1 |
| Topart, D | 1 |
| Pinzani, V | 1 |
| Jourdan, J | 1 |
| Morcos, F | 1 |
| Smith, E | 1 |
| Siemens, HJ | 1 |
| Gerke, P | 1 |
| Steinhoff, J | 1 |
| Roth-Isigkeit, A | 1 |
| Wagner, K | 1 |
| Brückner, S | 1 |
| Mounter, PJ | 1 |
| Schmidt, CG | 1 |
| Kuenn, JW | 1 |
| Weber, R | 1 |
| Teague, PO | 1 |
| Keitt, AS | 1 |
| Menefee, MG | 1 |
| Zellner, DC | 1 |
| Wright, RC | 1 |
| Patnaik, AK | 1 |
| Wilkins, RJ | 1 |
| Mattsson, W | 1 |
| von Eyben, F | 1 |
| Turesson, I | 1 |
| Icli, F | 1 |
| Costello, W | 1 |
| Berard, CW | 2 |
| Bennett, JM | 1 |
| Carbone, PP | 1 |
| Farr, MJ | 1 |
| Newling, DW | 1 |
| Raper, C | 1 |
| Kaufman, JH | 1 |
| Ezdinli, E | 2 |
| Aungst, CW | 5 |
| Pocock, S | 1 |
| Silverstein, M | 1 |
| Horton, J | 1 |
| Bennett, J | 1 |
| Bakemeier, R | 1 |
| Stolbach, L | 1 |
| Perlia, C | 1 |
| Brunk, SF | 1 |
| Lenhard, RE | 2 |
| Klaassen, DJ | 1 |
| Richter, P | 2 |
| Carbone, P | 1 |
| Hill, BH | 1 |
| Mittelman, A | 1 |
| Murphy, GP | 1 |
| Móller, TR | 1 |
| Brandt, L | 1 |
| Kónyves, I | 1 |
| Lindberg, G | 1 |
| Platanias, LC | 1 |
| Putterman, AM | 1 |
| Vijayakumar, S | 1 |
| Recant, W | 1 |
| Weichselbaum, RR | 1 |
| Bitran, JD | 1 |
| Coma, A | 1 |
| Jonte, F | 1 |
| Zanabili, Y | 1 |
| Soto, I | 1 |
| Fanjul, F | 1 |
| Carrera, D | 1 |
| Rayón, C | 1 |
| Luño, E | 1 |
| Jalón, S | 1 |
| Pinto, V | 1 |
| O'Brien, ME | 1 |
| Easterbrook, P | 1 |
| Powell, J | 1 |
| Blackledge, GR | 1 |
| MacLennan, IC | 1 |
| Loos, U | 1 |
| Musch, E | 1 |
| Malek, M | 1 |
| Riedel, E | 1 |
| Thomas, DW | 1 |
| Gray, W | 1 |
| Tate, RJ | 1 |
| Ba-Thike, K | 1 |
| Oo, N | 1 |
| Watkin, SW | 1 |
| Green, JA | 1 |
| Daxecker, F | 1 |
| Neuner, HP | 1 |
| Kienpointner, G | 1 |
| Stühlinger, W | 1 |
| Gisselbrecht, C | 1 |
| Lepage, E | 1 |
| Sebban, C | 1 |
| Coiffier, B | 1 |
| Jahn, H | 1 |
| Ruffert, K | 1 |
| Syrbe, G | 1 |
| Kühn, R | 1 |
| Jorke, D | 1 |
| Szántó, I | 1 |
| Fleischmann, T | 1 |
| Eckhardt, S | 1 |
| Clark, RH | 1 |
| Dimitrov, NV | 1 |
| Axelson, JA | 1 |
| Charamella, LJ | 1 |
| Stott, PB | 1 |
| Chisesi, T | 2 |
| Capnist, G | 2 |
| Vespignani, M | 2 |
| Dini, E | 1 |
| Hitchins, RN | 1 |
| Hocker, GA | 1 |
| Thomson, DB | 1 |
| Allan, NC | 1 |
| McGillivray, JB | 1 |
| Cetto, G | 1 |
| Steward, WP | 1 |
| Crowther, D | 2 |
| McWilliam, LJ | 1 |
| Jones, JM | 1 |
| Deakin, DP | 1 |
| Todd, ID | 1 |
| Blackledge, G | 1 |
| Wagstaff, J | 2 |
| Scarffe, JH | 2 |
| Harris, M | 1 |
| Bird, MC | 1 |
| Bosanquet, AG | 1 |
| Forskitt, S | 1 |
| Gilby, ED | 1 |
| Portlock, CS | 1 |
| Fischer, DS | 1 |
| Cadman, E | 1 |
| Lundberg, WB | 1 |
| Levy, A | 1 |
| Bobrow, S | 1 |
| Bertino, JR | 1 |
| Farber, L | 1 |
| Richards, MA | 1 |
| Barnett, MJ | 1 |
| Stansfeld, AG | 1 |
| Steigbigel, RT | 1 |
| Kim, H | 1 |
| Potolsky, A | 1 |
| Schrier, SL | 1 |
| Armstrong, JG | 1 |
| Druet, P | 1 |
| Dryll, A | 1 |
| Ryckewaert, A | 1 |
| de Sèze, S | 1 |
| Kahn, MF | 1 |
| Bessot, M | 1 |
| Brouant, JF | 1 |
| Laurent, J | 1 |
| Macinot, C | 1 |
| Kourilsky, R | 1 |
| Kourilsky, S | 1 |
| Piéron, R | 1 |
| Lesobre, B | 1 |
| Bernueau, J | 1 |
| Hunold, W | 1 |
| Gunz, FW | 1 |
| Levi, JA | 1 |
| Lind, DE | 1 |
| Vincent, PC | 1 |
| Reilly, CJ | 1 |
| Slack, NH | 1 |
| Webster, J | 1 |
| Pinkhas, J | 1 |
| Oliver, I | 1 |
| De Vries, A | 1 |
| Spitzer, SA | 1 |
| Henig, E | 1 |
| Fayemi, AO | 1 |
| Williams, J | 1 |
| Cuttner, J | 1 |
| Stojcevski, T | 1 |
| Mukherji, B | 1 |
| Yagoda, A | 1 |
| Lee, BJ | 1 |
| Krakoff, IH | 1 |
| Zittoun, R | 1 |
| Debré, P | 1 |
| Gardais, J | 1 |
| Thuau, FP | 1 |
| Renier, JC | 1 |
| Simon, F | 1 |
| Halkin, H | 1 |
| Meytes, D | 1 |
| Militeanu, J | 1 |
| Ramot, B | 1 |
| Berceanu, S | 1 |
| Sighetea, E | 1 |
| Gociu, M | 1 |
| Ghetie, I | 1 |
| Stoica, GH | 1 |
| Voiosu, R | 1 |
| McElwain, TJ | 1 |
| Jacobs, EM | 1 |
| Peters, FC | 1 |
| Luce, JK | 1 |
| Zippin, C | 1 |
| Rosenberg, SA | 1 |
| Kaung, DT | 1 |
| Wittington, RM | 1 |
| Spencer, H | 1 |
| Patno, ME | 1 |
| Calamera, JC | 1 |
| Morgenfeld, MC | 2 |
| Kierszenbaum, AL | 1 |
| Lavieri, JC | 1 |
| Mancini, RE | 1 |
| Cohen, ML | 1 |
| Weiss, EB | 1 |
| Miller, DG | 1 |
| Presant, CA | 1 |
| Wiernik, PH | 1 |
| Serpick, AA | 1 |
| Helft, F | 1 |
| Bomchil, G | 1 |
| Osterberg, G | 1 |
| Rausing, A | 1 |
| Hartwich, G | 1 |
| Butzler, W | 1 |
| Henefer, EP | 1 |
| Nelson, JF | 1 |
| Beaupre, EM | 1 |
| Gosselin, G | 1 |
| Neemeh, J | 1 |
| Long, LA | 1 |
| Pretty, H | 1 |
| Lefebvre, R | 1 |
| White, LP | 1 |
| Owens, AH | 1 |
| Kissel, P | 1 |
| Debry, G | 1 |
| Royer, R | 1 |
| Picard, L | 1 |
| Lewis, FB | 1 |
| Schwartz, RS | 1 |
| Dameshek, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| US Post-Marketing Retrospective Observational Safety Study of Moxetumomab Pasudotox-tdfk (LUMOXITI)(TM)[NCT04125290] | 2 participants (Actual) | Observational | 2019-12-09 | Terminated (stopped due to Study stopped due to lack of recruitment.) | |||
| Immune Reconstitution With Blinatumomab Expanded T-cells (BET) After First-line Treatment With Fludarabine-Cyclophosphamide-Rituximab or Bendamustine-Rituximab in CD20+ Indolent Non-Hodgkin Lymphomas/Chronic Lymphocytic Leukemia: a Phase I Study[NCT03823365] | Phase 1 | 19 participants (Actual) | Interventional | 2018-12-17 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for chlorambucil and Lymphoma, Non-Hodgkin
| Article | Year |
|---|---|
Fludarabine combination therapy for the treatment of chronic lymphocytic leukemia.
Topics: Adolescent; Adult; Aged; Alemtuzumab; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antibodie | 2002 |
Economic assessment on the management of chronic lymphocytic leukaemia.
Topics: Algorithms; Antibodies, Monoclonal; Antineoplastic Agents; Chlorambucil; Cost-Benefit Analysis; Heal | 2005 |
Immunosuppressive drugs in multiple sclerosis: pro and con.
Topics: Adrenocorticotropic Hormone; Alkylating Agents; Antimetabolites; Azathioprine; Chlorambucil; Cycloph | 1980 |
[Metastatic malignant melanoma in treated non-Hodgkin's lymphoma].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Humans; Lymph Nodes; Lymphatic | 1996 |
Chlorambucil-induced seizures.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Chlorambucil; Humans; Lymphoma, Non-Hodg | 1997 |
Chlorambucil.
Topics: Animals; Carcinogens; Chlorambucil; Drug Evaluation, Preclinical; Female; Fetus; Humans; Lethal Dose | 1975 |
32 trials available for chlorambucil and Lymphoma, Non-Hodgkin
| Article | Year |
|---|---|
Randomized phase III study for the treatment of advanced indolent non-Hodgkin's lymphomas (NHL) and mantle cell lymphoma: chemotherapy versus chemotherapy plus rituximab.
Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplas | 2003 |
Long-term effect of a watch and wait policy versus immediate systemic treatment for asymptomatic advanced-stage non-Hodgkin lymphoma: a randomised controlled trial.
Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Cause of Death; Chlorambuci | 2003 |
Chlorambucil in combination with induction and maintenance rituximab is feasible and active in indolent non-Hodgkin's lymphoma.
Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined | 2003 |
A phase I/II study examining pentostatin, chlorambucil, and theophylline in patients with relapsed chronic lymphocytic leukemia and non-Hodgkin's lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Diseas | 2006 |
The addition of oral idarubicin to a chlorambucil/dexamethasone combination has a significant impact on time to treatment failure but none on overall survival in patients with low grade non-Hodgkin's lymphoma: Results of the Scotland and Newcastle Lymphom
Topics: Administration, Oral; Adolescent; Adult; Aged; Chlorambucil; Dexamethasone; Disease Progression; Dru | 2006 |
Rituximab and chlorambucil as first-line treatment for low-grade ocular adnexal lymphomas.
Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplas | 2007 |
Treatment of chronic lymphocytic leukaemia and well-differentiated lymphocytic lymphoma with continuous low- or intermittent high-dose prednimustine versus chlorambucil/prednisolone.
Topics: Adult; Aged; Chlorambucil; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; | 1982 |
Chlorambucil/prednisone vs. CHOP in symptomatic low-grade non-Hodgkin's lymphomas: a randomized trial from the Lymphoma Group of Central Sweden.
Topics: Actuarial Analysis; Aged; Antineoplastic Combined Chemotherapy Protocols; Cause of Death; Chlorambuc | 1994 |
Autologous bone marrow transplantation in poor-risk high-grade non-Hodgkin's lymphoma in first complete remission. Newcastle and Northern Lymphoma Group.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Blood Platelets; Bone | 1994 |
Chlorambucil, vincristine and cytarabine (COA) treatment of low grade lymphomas.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chlorambucil; Cytara | 1995 |
Mitoxantrone, chlorambucil and prednisolone in the treatment of non-Hodgkin's lymphoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Female; Humans; Lymphoma, | 1994 |
A British National Lymphoma Investigation randomised trial of single agent chlorambucil plus radiotherapy versus radiotherapy alone in low grade, localised non-Hodgkins lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Chlorambucil; Female; Follow-Up Studies; Humans; Lymphoma, Non-Hodgk | 1994 |
Phase I study of combined 2-chlorodeoxyadenosine and chlorambucil in chronic lymphoid leukemia and low-grade lymphoma.
Topics: 2-Chloroadenosine; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chloramb | 1994 |
Combined use of interferon alpha-2, chlorambucil and prednisone in previously treated patients with low-grade non-Hodgkin's lymphomas. Results of a phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Female; Humans; Interfero | 1993 |
Mitoxantrone, teniposide, chlorambucil and prednisone (MVLP) for relapsed non-Hodgkin's lymphoma. The impact of advanced age and performance status.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophospha | 1993 |
High-dose chlorambucil and dexamethasone for relapsed non-Hodgkin's lymphomas.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Dexame | 1993 |
Treatment of refractory low grade lymphoma with chlorambucil alternating with interferon and radiotherapy.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined Moda | 1995 |
Treatment of mantle-cell lymphomas with the VAD +/- chlorambucil regimen with or without subsequent high-dose therapy and peripheral blood stem-cell transplantation.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined Modality Therapy; Cyclo | 1997 |
CHOP-based chemotherapy is as effective as alternating PEEC/CHOP chemotherapy in a randomised trial in high-grade non-Hodgkin's lymphoma. Scotland and Newcastle Lymphoma Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cyclophosphami | 1997 |
Clinical features, treatment and outcome in a series of 93 patients with low-grade gastric MALT lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antineoplastic Agents, Alkylating; Antineopla | 1997 |
Primary treatment of low-grade non-Hodgkin's lymphoma using an all oral anthracycline-containing regimen, chlorambucil, idarubicin, dexamethasone (CID)--a phase II study.
Topics: Administration, Oral; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy | 2000 |
Low-dose continuous chemotherapy (LBCMVD-56) for refractory and relapsing lymphoma.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; De | 2000 |
A phase II clinical trial of prednimustine. Clinical screening cooperative group of E.O.R.T.C.
Topics: Adolescent; Adult; Aged; Chlorambucil; Clinical Trials as Topic; Female; Humans; Leukemia, Lymphoid; | 1977 |
Lymphosarcoma. A comparison of extended to conservative chemotherapy.
Topics: Adult; Aged; Carmustine; Chlorambucil; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; | 1976 |
Treatment of chronic lymphocytic leukemia and lymphosarcoma with a new chlorambucil ester of prednisolone (Leo 1031) (NSC-134087).
Topics: Chlorambucil; Clinical Trials as Topic; Female; Humans; Leukemia, Lymphoid; Lymphoma, Non-Hodgkin; P | 1975 |
Comparative pharmacokinetics of chlorambucil and prednimustine after oral administration.
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chlora | 1991 |
[Low-grade non-Hodgkin's lymphoma in the adult: new therapeutic approaches].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Doxorubicin; | 1987 |
Prednimustine treatment in malignant lymphomas.
Topics: Adult; Aged; Chlorambucil; Clinical Trials as Topic; Female; Hodgkin Disease; Humans; Lymphoma, Non- | 1989 |
Interferon alfa-2b and chlorambucil in the treatment of non-Hodgkin's lymphoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Clinical Trials as Topic; Female | 1987 |
Maintenance chlorambucil after CVP in the management of advanced stage, low-grade histologic type non-Hodgkin's lymphoma. A randomized prospective study with an assessment of prognostic factors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Drug Evaluation; Fem | 1988 |
Mechlorethamine HCl and cyclophosphamide in the treatment of Hodgkin's disease and the lymphomas.
Topics: Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Dosage Forms; Follow-Up Studies; Hodgkin D | 1968 |
Comparison of chlorambucil and streptonigrin (NSC-45383) in the treatment of malignant lymphomas.
Topics: Antibiotics, Antineoplastic; Bone Marrow; Chlorambucil; Clinical Trials as Topic; Digestive System; | 1969 |
115 other studies available for chlorambucil and Lymphoma, Non-Hodgkin
| Article | Year |
|---|---|
Demographics and Outome in Paediatric Non-Hodgkin Lymphoma: Single Centre Experience at The Children Hospital Lahore, Pakistan.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Child; Child, Preschoo | 2018 |
Feline small cell lymphosarcoma versus inflammatory bowel disease: treatment and prognosis.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Cat Diseases; Cats; Chlorambucil; Diet; Gastr | 2013 |
Chlorambucil-rituximab as first-line therapy in patients affected by follicular non-Hodgkin's lymphoma: a retrospective single-centre study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Chlorambucil; Female; Humans; Lym | 2015 |
Clinical investigations in aggressive non-Hodgkin lymphoma.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antineoplasti | 2008 |
Increased incidence of transformation and myelodysplasia/acute leukemia in patients with Waldenström macroglobulinemia treated with nucleoside analogs.
Topics: Adult; Aged; Aged, 80 and over; Cell Transformation, Neoplastic; Chlorambucil; Cladribine; Female; F | 2009 |
Chlorambucil and acute intermittent porphyria.
Topics: Antineoplastic Agents, Alkylating; Chlorambucil; Female; Humans; Lymphoma, Non-Hodgkin; Middle Aged; | 2002 |
Chemotherapy of malignant disease. II. Diseases of lymphoid tissue and bone marrow.
Topics: Adrenal Cortex Hormones; Aged; Bone Marrow; Busulfan; Chlorambucil; Cyclophosphamide; Hodgkin Diseas | 1962 |
THE MALIGNANT LYMPHOMAS.
Topics: Adrenal Cortex Hormones; Chlorambucil; Cyclophosphamide; Hodgkin Disease; Humans; Lymphoma; Lymphoma | 1963 |
ENTERIC PROTEIN LOSS WITH HYPOPROTEINEMIA IN DIFFUSE LYMPHOSARCOMA OF THE BOWEL.
Topics: Aged; Biopsy; Blood Protein Disorders; Chlorambucil; Edema; Humans; Hypocalcemia; Hypoproteinemia; I | 1963 |
CLINICAL EVALUATION OF URACIL MUSTARD.
Topics: Anemia; Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Female; Hodgkin Disease; Humans; Kidn | 1963 |
THE RETICULOSES.
Topics: Adrenal Cortex Hormones; Chlorambucil; Cyclophosphamide; Dermatitis, Exfoliative; Genetic Diseases, | 1964 |
[CURRENT PRACTICE IN THE TREATMENT OF TUMORS WITH INTRA-ARTERIAL INJECTIONS OF ANTINEOPLASTIC SUBSTANCES].
Topics: Aminopterin; Antineoplastic Agents; Carcinoma; Chemotherapy, Cancer, Regional Perfusion; Chlorambuci | 1963 |
WEEKLY HIGH-DOSAGE GLUCOCORTICOSTEROID TREATMENT OF LYMPHOCYTIC LEUKEMIAS AND LYMPHOMAS.
Topics: Anemia; Anemia, Hemolytic; Betamethasone; Chlorambucil; Dexamethasone; Geriatrics; Humans; Leukemia; | 1964 |
PHAGOCYTOSIS IN RETICULUM CELL SARCOMA.
Topics: Adolescent; Black People; Child; Chlorambucil; Cyclophosphamide; Dactinomycin; Geriatrics; Leukemia; | 1964 |
SPINAL-CORD COMPRESSION IN THE MALIGNANT LYMPHOMAS.
Topics: Chlorambucil; Hematopoiesis; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Mercaptopurin | 1964 |
[HISTOPATHOLOGICAL EFFECTS OF ANTINEOPLASTIC AGENTS ON MALIGNANT LYMPHOMA].
Topics: Antineoplastic Agents; Child; Chlorambucil; Cyclophosphamide; Dactinomycin; Geriatrics; Hodgkin Dise | 1964 |
LONG TERM RESULTS ACHIEVED WITH THE USE OF ALKYLATING AGENTS IN MALIGNANT LYMPHOMA AND HODGKIN'S DISEASE.
Topics: Alkylating Agents; Chlorambucil; Cyclophosphamide; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Larg | 1964 |
[ISOLATED PULMONARY LYMPHOCYTOSARCOMAS].
Topics: Bronchoscopy; Chlorambucil; Cyclophosphamide; Humans; Lung; Lung Neoplasms; Lymphoma, Non-Hodgkin; P | 1964 |
NONSURGICAL TREATMENT OF PULMONARY CANCER.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adrenal Cortex Hormones; Alkylating Agents; Antineoplastic Agen | 1964 |
CHROMOSOMES OF LYMPHOSARCOMA AND CANCER CELLS IN BONE MARROW.
Topics: Alkaloids; Antineoplastic Agents; Bone Marrow; Bone Marrow Examination; Chlorambucil; Chromosome Abe | 1964 |
THE MANAGEMENT OF LEUKEMIA AND LYMPHOMA.
Topics: Adrenal Cortex Hormones; Busulfan; Chlorambucil; Cortisone; Cyclophosphamide; Hodgkin Disease; Human | 1964 |
CHLORAMBUCIL THERAPY FOR LYMPHOMAS AND CHRONIC LYMPHOCYTIC LEUKEMIA.
Topics: Adrenal Cortex Hormones; Chlorambucil; Drug Synergism; Hodgkin Disease; Leukemia; Leukemia, Lymphocy | 1965 |
ESSENTIAL MACROGLOBULINEMIA. REPORT OF A CASE INCLUDING IMMUNOFLUORESCENT AND ELECTRON MICROSCOPIC STUDIES.
Topics: Blood Protein Electrophoresis; Bone Marrow Cells; Chlorambucil; Electrons; Fluorescent Antibody Tech | 1965 |
Effect of chlorambucil on synthesis of protein and nucleic acids in tumor-bearing mice.
Topics: Animals; Chlorambucil; Lymphoma, Non-Hodgkin; Mechlorethamine; Mice; Neoplasms; Nitrogen Mustard Com | 1960 |
[Results obtained with the use of chlorambucil in the treatment of malignant lymphopathies].
Topics: Chlorambucil; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodg | 1961 |
[Principles of treatment and military medical examination of the patients with indolent Non-Hodgkin's lymphomas].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cohort Studies; Combined Modalit | 2003 |
Urinary immunocytology for primary bladder B cell lymphoma.
Topics: Aged; Antigens, CD20; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocy | 2004 |
High dose chlorambucil in the treatment of lymphoid malignancies.
Topics: Antineoplastic Agents, Alkylating; Chlorambucil; Clinical Trials as Topic; Hodgkin Disease; Humans; | 2004 |
Effective treatment of indolent non-hodgkin's lymphomas with mitoxantrone, chlorambucil and prednisone.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Di | 2005 |
Necrobiotic xanthogranuloma associated with paraproteinemia and non-Hodgkin's lymphoma developing into chronic lymphocytic leukemia: the first case reported in the literature and review of the literature.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyc | 2006 |
Peripheral T-lymphocyte subsets in patients treated with Rituximab-Chlorambucil combination therapy for indolent NHL.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; CD4-Positive | 2006 |
Case of chlorambucil-induced seizure.
Topics: Aged; Chlorambucil; Humans; Lymphoma, Non-Hodgkin; Male; Seizures | 2006 |
Action of elatericin A on human leukemic and normal lymphocytes.
Topics: Aminopterin; Animals; Antineoplastic Agents; Azirines; Cathartics; Cell Nucleus; Chlorambucil; Cyclo | 1967 |
Complete remission in chronic lymphocytic leukemia and leukolymphosarcoma.
Topics: Aged; Chlorambucil; Female; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma, Non-Hodgkin; Male; Middl | 1967 |
Chronic lymphocytic leukemia in the elderly.
Topics: Aged; B-Lymphocytes; Chlorambucil; Diagnosis, Differential; Glucosephosphate Dehydrogenase; Humans; | 1982 |
Mycosis fungoides and lymphoplasmacytoid immunocytoma in the same patient. A case report.
Topics: Chlorambucil; Cytoplasm; Female; Hematologic Tests; Humans; Immunoglobulin lambda-Chains; Immunoglob | 1984 |
Lymphoma in primary chronic cold hemagglutinin disease treated with chlorambucil.
Topics: Anemia, Hemolytic, Autoimmune; Chlorambucil; Chronic Disease; Cold Temperature; Humans; Lymphoma, La | 1982 |
Cold agglutinin disease in non-Hodgkin's lymphoma.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Anemia, Hemolytic, Autoimmune; | 1995 |
Cutaneous B-cell lymphoma with subsequent laryngeal involvement.
Topics: Aged; Chlorambucil; Humans; Laryngeal Neoplasms; Lymphoma, B-Cell; Lymphoma, Non-Hodgkin; Male; Radi | 1995 |
Pemphigus foliaceus and non-Hodgkin's lymphoma.
Topics: Allopurinol; Chlorambucil; Drug Therapy, Combination; Female; Fluorescent Antibody Technique; Humans | 1994 |
Treatment and prognosis of centrocytic (mantle cell) lymphoma: a retrospective analysis of twenty-six patients treated in one institution.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Female | 1994 |
Assessment of potential doubling time (Tpot), argyrophilic nucleolar organizer regions (AgNOR), and proliferating cell nuclear antigen (PCNA) as predictors of therapy response in canine non-Hodgkin's lymphoma.
Topics: Animals; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Chloramb | 1996 |
[New approach to the treatment of primary malignant non-Hodgkin's lymphoma of the stomach].
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Ant | 1996 |
Myoclonus due to chlorambucil in two adults with lymphoma.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Chlorambucil; Female; Humans; Leukemia, Lymphocytic, | 1997 |
Primary non-Hodgkin's lymphoma of the mandible: a case report.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Cell Nucleolus; Cell Nucleus; Chlorambuc | 1997 |
Ureteric obstruction due to B-cell lymphoma.
Topics: Antineoplastic Agents, Alkylating; Chlorambucil; Humans; Lymphoma, B-Cell; Lymphoma, Non-Hodgkin; Ma | 1997 |
[Secondary myelodysplastic syndrome].
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Bone Marrow Transplantation; Chlorambucil; Cyclophos | 1997 |
Prolonged disease-free survival in relapsed/refractory low-grade lymphoma treated with fludarabine: a report of four cases.
Topics: Adult; Anthracyclines; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Comb | 1998 |
[Prognostic factors in low-grade lymphoma].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; B | 1998 |
Central retinal vein occlusion in a patient with IgG lambda monoclonal gammopathy.
Topics: Aged; Bone Marrow; Chlorambucil; Drug Therapy, Combination; Fluorescein Angiography; Humans; Hyperga | 1999 |
Interstitial pneumonitis following mitozantrone, chlorambucil and prednisolone (MCP) chemotherapy.
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Female; H | 1999 |
Secondary cutaneous infiltration in B cell chronic lymphocytic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Doxorubicin; Histidi | 2000 |
Chlorambucil/prednisone-induced seizures in a patient with non-Hodgkin's lymphoma.
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Drug | 2001 |
Sciatica or spinal lymphoma.
Topics: Aged; Antineoplastic Agents, Alkylating; Chlorambucil; Diagnosis, Differential; Humans; Lymphoma, B- | 2002 |
A prolonged APTT in a patient with a low grade malignant NHL - a case report.
Topics: Anemia; Antineoplastic Combined Chemotherapy Protocols; Autoantibodies; Blood Coagulation Factors; C | 2002 |
High-dose chlorambucil for the treatment of chronic lymphocytic leukaemia and low-grade non-Hodgkin's lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Anemia, Hemolytic, Autoimmune; Antineoplastic Agents, Alkylating; Ch | 2002 |
[Chemotherapy in non-Hodgkin's lymphomas (author's transl)].
Topics: Antineoplastic Agents; Bleomycin; Burkitt Lymphoma; Chlorambucil; Cyclophosphamide; Doxorubicin; Dru | 1977 |
Cryopathic gangrene with an IgM lambda cryoprecipitating cold agglutinin.
Topics: Adult; Agglutinins; Autoantibodies; Breast Neoplasms; Chlorambucil; Cryoglobulins; Female; Gangrene; | 1978 |
The Sézary syndrome. A case with fetal-type glycogen and lymphocytic lymphoma.
Topics: Chlorambucil; Cytoplasmic Granules; Dermatitis, Exfoliative; Glycogen; Humans; Lymphoma, Non-Hodgkin | 1978 |
Diagnosis and treatment of canine hematopoietic neoplasms.
Topics: Animals; Chlorambucil; Dog Diseases; Dogs; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma | 1977 |
Prednimustine (NSC-134087, Leo 1031) treatment of lymphocytic and lymphocytic-histiocytic lymphomas.
Topics: Bone Marrow; Chlorambucil; Female; Humans; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; M | 1978 |
Diffuse well-differentiated lymphocytic lymphoma (DLWD): response and survival.
Topics: Aged; Antineoplastic Agents; Carmustine; Cell Differentiation; Chlorambucil; Cyclophosphamide; Drug | 1978 |
Simple chemotherapy for bladder lymphoma with bilateral hydronephrosis.
Topics: Chlorambucil; Humans; Hydronephrosis; Lymphoma, Non-Hodgkin; Male; Middle Aged; Prednisolone; Urinar | 1978 |
Comparison of intensive versus moderate chemotherapy of lymphocytic lymphomas: a progress report.
Topics: Adult; Aged; Chlorambucil; Cyclophosphamide; Drug Combinations; Ethylnitrosourea; Evaluation Studies | 1976 |
Immunosuppressive drug therapy as a potentiator of skin tumours in five patients with lymphoma.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Chlorambucil; H | 1976 |
Therapeutic effect of Leo 1031, an alkylating corticosteroid ester; in lymphoproliferative disorders. II. Lymphocytic lymphoma.
Topics: Adult; Aged; Bone Marrow; Chlorambucil; Drug Evaluation; Drug Therapy, Combination; Esters; Female; | 1975 |
Treatment and prognosis of orbital non-Hodgkin's lymphomas.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cyclophosphamide; Cyt | 1992 |
[Low-grade non-Hodgkin's lymphomas. Study of 73 cases].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclop | 1992 |
The natural history of low grade non-Hodgkin's lymphoma and the impact of a no initial treatment policy on survival.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophospha | 1991 |
Non-Hodgkin's lymphoma presenting at the site of a recent dental extraction: a report of two cases.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Humans; Jaw Neoplasms; Ly | 1991 |
Non-Hodgkin's lymphoma in pregnancy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Female; Fetus | 1990 |
Non-Hodgkin's lymphoma. A four-drug regimen suitable for elderly patients with advanced disease.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Drug Evaluation; Female; Humans; | 1990 |
[Papilledema and macular edema as first symptom of non-Hodgkin's lymphoma].
Topics: Aged; Chlorambucil; Edema; Fluorescein Angiography; Fundus Oculi; Humans; Lymphoma, Non-Hodgkin; Mac | 1990 |
Results of treating stage III and IV malignant non-Hodgkin's lymphomas (NHL).
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cyclophosphamide; Doxorubic | 1988 |
A phase II trial of intermittent leukocyte interferon and high dose chlorambucil in the treatment of non-Hodgkin's lymphoma resistant to conventional therapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Drug A | 1989 |
The role of interferon alfa-2b and chlorambucil in the treatment of non-Hodgkin's lymphoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Bone Marrow; Chlorambucil; Huma | 1988 |
Chlorambucil allergy--a series of three cases.
Topics: Aged; Chlorambucil; Drug Eruptions; Female; Humans; Lymphoma, Non-Hodgkin; Male; Middle Aged; Patch | 1987 |
Methylprednisolone, etoposide, vindesine, and chlorambucil (PEEC) alone or alternating with CHOP as initial or salvage therapy for non-Hodgkin's lymphoma.
Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamid | 1988 |
Long-term comparison of results of a drug sensitivity assay in vitro with patient response in lymphatic neoplasms.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Drug Screening | 1988 |
Clinical use of interferon alfa-2b (intron-A): the Manchester experience.
Topics: Chlorambucil; Combined Modality Therapy; Drug Evaluation; Humans; Infusions, Intravenous; Injections | 1987 |
High-dose pulse chlorambucil in advanced, low-grade non-Hodgkin's lymphoma.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Chlorambucil; Female; Humans; Lymphoma, Non-Ho | 1987 |
Chlorambucil and interferon for low grade non-Hodgkin's lymphoma.
Topics: Adult; Aged; Chlorambucil; Combined Modality Therapy; Humans; Interferon Type I; Lymphoma, Non-Hodgk | 1987 |
Acute myeloproliferative disorder following long-term chlorambucil therapy.
Topics: Biopsy; Bone Marrow; Chlorambucil; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Long | 1974 |
Current problems in the use of the oncolytic drugs.
Topics: Antineoplastic Agents; Busulfan; Carcinoma, Squamous Cell; Child; Chlorambucil; Choriocarcinoma; Dac | 1968 |
[Rheumatoid polyarthritis and chronic lymphoid leukemia. Studies of 7 cases of association of these 2 diseases].
Topics: Adult; Age Factors; Aged; Animals; Antibodies; Arthritis, Rheumatoid; Autoimmune Diseases; Chlorambu | 1969 |
[Lymphoid tumor of the stomach].
Topics: Chlorambucil; Female; Humans; Lymphocytosis; Lymphography; Lymphoma, Non-Hodgkin; Middle Aged; Stoma | 1969 |
[Waldenström's disease and pulmonary images. 2 cases].
Topics: Blood Sedimentation; Chlorambucil; Humans; Lung Neoplasms; Lymphoma, Non-Hodgkin; Male; Middle Aged; | 1970 |
[Letter: Progredient liver cirrhosis in chronic lymphatic leukemia].
Topics: Chlorambucil; Diabetes Complications; Hepatitis B; Humans; Leukemia, Lymphoid; Liver Cirrhosis; Lymp | 1974 |
Development of acute leukaemia in a patient with lymphosarcoma.
Topics: Autopsy; Bone Marrow; Bone Marrow Cells; Chlorambucil; Humans; Immunoglobulins; Karyotyping; Leukemi | 1973 |
Reticulum cell sarcoma. A review of radiotherapeutic experience.
Topics: Adolescent; Adult; Aged; Chlorambucil; Female; Follow-Up Studies; Humans; Lymphoma, Non-Hodgkin; Mal | 1972 |
Pulmonary nocardiosis complicating malignant lymphoma successfully treated with chemotherapy.
Topics: Agammaglobulinemia; Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Humans; Lung Diseases; Ly | 1973 |
Treatment of Hodgkin's disease and other malignant lymphomas.
Topics: Alkylating Agents; Antineoplastic Agents; Carmustine; Chlorambucil; Cyclohexanes; Cyclophosphamide; | 1973 |
Effect of BCG on delayed hypersensitivity responses of patients with neoplastic disease.
Topics: Animals; Antigen-Antibody Reactions; BCG Vaccine; Cattle; Chlorambucil; Cyclophosphamide; Hodgkin Di | 1973 |
Systemic Weber-Christian disease and thrombocythemia terminating in reticulum-cell sarcoma.
Topics: Adipose Tissue; Adult; Agammaglobulinemia; Arteritis; Arthritis, Rheumatoid; Autopsy; Blood Platelet | 1974 |
Haemolytic anaemia in malignant lymphoreticuloendothelial diseases.
Topics: Adult; Anemia, Hemolytic; Anemia, Hemolytic, Autoimmune; Autoantibodies; Bone Marrow Examination; Ce | 1974 |
A clinical study of the natural history of lymphosarcoma and reticulum cell sarcoma.
Topics: Adult; Aged; Chlorambucil; Cyclophosphamide; Female; Humans; Lymph Nodes; Lymphoma, Non-Hodgkin; Mal | 1974 |
[Small intestine lymphosarcoma after treatment of rheumatoid arthritis with chlorambucil].
Topics: Aged; Arthritis, Rheumatoid; Blood Cell Count; Chlorambucil; Female; Humans; Intestinal Neoplasms; I | 1972 |
Multiple lymphomatous polyposis of the gastrointestinal tract.
Topics: Autopsy; Biopsy; Celiac Disease; Chlorambucil; Gastrointestinal Neoplasms; Humans; Intestinal Polyps | 1973 |
Peculiar forms of monoclonal gammapathies.
Topics: Adrenal Cortex Hormones; Antigen-Antibody Complex; Blood Protein Disorders; Chlorambucil; Cryoglobul | 1973 |
Chemotherapy of the lymphomas.
Topics: Adult; Burkitt Lymphoma; Child; Chlorambucil; Cyclophosphamide; Doxorubicin; Drug Therapy, Combinati | 1974 |
Contribution of lymphangiography to our understanding of lymphoma.
Topics: Chlorambucil; Hodgkin Disease; Humans; Lymphography; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymp | 1968 |
Effect of chlorambucil on spermatogenesis in the human with malignant lymphoma.
Topics: Adolescent; Adult; Biopsy; Chlorambucil; Hodgkin Disease; Humans; Infertility, Male; Lymphoma; Lymph | 1970 |
Pneumocystitis carinii pneumonia: percutaneous lung biopsy and review of literature.
Topics: Adolescent; Adult; Agammaglobulinemia; Amphotericin B; Anuria; Azathioprine; Biopsy; Bis-Trimethylam | 1971 |
Alkylating agents and human spermatogenesis.
Topics: Adolescent; Adult; Alkylating Agents; Chlorambucil; Cyclophosphamide; Hodgkin Disease; Humans; Lymph | 1971 |
Disseminated extrapulmonary nocardiosis presenting as a renal abscess.
Topics: Abscess; Adult; Anemia, Hemolytic, Autoimmune; Autopsy; Brain Diseases; Chlorambucil; Diagnosis, Dif | 1970 |
[Different response of superficial and deep lymph nodes to drug therapy in malignant lymphoreticulopathy].
Topics: Aged; Chlorambucil; Cyclophosphamide; Female; Humans; Leukemia, Lymphoid; Lymph Nodes; Lymphoma, Lar | 1969 |
Reticulum cell sarcoma in Waldenström's macroglobulinemia after chlorambucil treatment.
Topics: Amyloidosis; Bone Marrow Cells; Bone Neoplasms; Chlorambucil; Female; Humans; Lymphoma, Non-Hodgkin; | 1970 |
[Secondary tumors in hemoblastoses during cytostatic treatment].
Topics: Adrenal Gland Neoplasms; Aged; Antineoplastic Agents; Bronchial Neoplasms; Busulfan; Carcinoma; Chlo | 1971 |
Spontaneous remission of leukemic lymphoproliferative disease.
Topics: Adult; Aged; Chlorambucil; Female; Humans; Leukemia, Lymphoid; Leukocyte Count; Lymphocytes; Lymphom | 1971 |
Palatal enlargement in chronic lymphocytic leukemia: report of case.
Topics: Aged; Chlorambucil; Edema; Humans; Leukemia, Lymphoid; Lymphatic Metastasis; Lymphoma, Non-Hodgkin; | 1970 |
[Appearance of acute myeloid leukemia during the development of lymphosarcoma].
Topics: Chlorambucil; Female; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Middle Aged | 1970 |
Leukemia and lymphoma.
Topics: Antineoplastic Agents; BCG Vaccine; Burkitt Lymphoma; Busulfan; Chlorambucil; Cyclophosphamide; Cyta | 1970 |
Recent advances in chemotherapy of lymphoma.
Topics: Alkylating Agents; Chlorambucil; Cyclophosphamide; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Larg | 1967 |
[Some reflections on the favorable effects of chlorambucil in unusual doses].
Topics: Aged; Chlorambucil; Female; Humans; In Vitro Techniques; Leukemia, Lymphoid; Lymphoma, Non-Hodgkin; | 1965 |
X-radiation and alkylating agents as possible "trigger" mechanisms in the autoimmune complications of malignant lymphophroliferative disease.
Topics: Adult; Aged; Anemia, Hemolytic, Autoimmune; Chlorambucil; Humans; Leukemia, Lymphoid; Lymphoma, Non- | 1966 |