chlorambucil has been researched along with Lupus Nephritis in 5 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Lupus Nephritis: Glomerulonephritis associated with autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Lupus nephritis is histologically classified into 6 classes: class I - normal glomeruli, class II - pure mesangial alterations, class III - focal segmental glomerulonephritis, class IV - diffuse glomerulonephritis, class V - diffuse membranous glomerulonephritis, and class VI - advanced sclerosing glomerulonephritis (The World Health Organization classification 1982).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Persistent hyperlipidemia increases the risk of cardiovascular diseases." | 2.42 | [Membranous nephropathy]. ( Godin, M; Legallicier, B; Passos, EM, 2003) |
| "Risk of ESRD by WHO class at 5 years was as follows: class III, 0%; IV, 9%; V, 16% (P = ." | 1.29 | Lupus in the 1980s: III. Influence of clinical variables, biopsy, and treatment on the outcome in 150 patients with lupus nephritis seen at a single center. ( Azen, C; Fichman, M; Klinenberg, JR; Metzger, AL; Nessim, S; Neumann, K; Wallace, DJ, 1995) |
| "Graves' disease was initially diagnosed in an 11-year-old Chinese boy in March 1989." | 1.28 | Class IV lupus nephritis associated with Graves' disease. ( Chao, T; Chen, WP; Fu, LS; Lin, CY; Ooi, SK; Yang, LY, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Passos, EM | 1 |
| Legallicier, B | 1 |
| Godin, M | 1 |
| Neumann, K | 1 |
| Wallace, DJ | 1 |
| Azen, C | 1 |
| Nessim, S | 1 |
| Fichman, M | 1 |
| Metzger, AL | 1 |
| Klinenberg, JR | 1 |
| Moroni, G | 1 |
| Maccario, M | 1 |
| Banfi, G | 1 |
| Quaglini, S | 1 |
| Ponticelli, C | 1 |
| Wang, AY | 1 |
| Li, PK | 1 |
| Lai, FM | 1 |
| Chow, KM | 1 |
| Szeto, CC | 1 |
| Leung, CB | 1 |
| Lui, SF | 1 |
| Fu, LS | 1 |
| Yang, LY | 1 |
| Chen, WP | 1 |
| Chao, T | 1 |
| Ooi, SK | 1 |
| Lin, CY | 1 |
1 review available for chlorambucil and Lupus Nephritis
| Article | Year |
|---|---|
[Membranous nephropathy].
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Basement Membrane; Child; Child, Preschool; Chlorambuci | 2003 |
4 other studies available for chlorambucil and Lupus Nephritis
| Article | Year |
|---|---|
Lupus in the 1980s: III. Influence of clinical variables, biopsy, and treatment on the outcome in 150 patients with lupus nephritis seen at a single center.
Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Biopsy; Blood Component Removal; Chlorambucil; Cyclop | 1995 |
Treatment of membranous lupus nephritis.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Chlorambucil; Drug Evaluation; Drug Therapy, Combination | 1998 |
Severe bone marrow failure associated with the use of alternating steroid with chlorambucil in lupus membranous nephropathy in Chinese.
Topics: Adult; Antineoplastic Agents, Alkylating; Bone Marrow; Bone Marrow Diseases; China; Chlorambucil; Fe | 2001 |
Class IV lupus nephritis associated with Graves' disease.
Topics: Carbimazole; Child; Chlorambucil; Graves Disease; Humans; Lupus Nephritis; Male; Prednisolone; Propy | 1992 |