chlorambucil has been researched along with Lung Diseases, Interstitial in 4 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Lung Diseases, Interstitial: A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of PULMONARY ALVEOLI that extends to the interstitium and beyond leading to diffuse PULMONARY FIBROSIS. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chlorambucil is a rare cause of pulmonary disease." | 2.38 | Interstitial lung disease--an underdiagnosed side effect of chlorambucil? ( Huhn, D; Kingreen, D; Mohr, M; Rühl, H, 1993) |
| "We describe two cases of interstitial lung disease in patients with non-Hodgkin's lymphoma who were treated with combination chemotherapy including mitozantrone." | 1.30 | Interstitial pneumonitis following mitozantrone, chlorambucil and prednisolone (MCP) chemotherapy. ( Johnson, S; Nicholson, AG; Rule, S; Stone, R; Tighe, M; Tomlinson, J, 1999) |
| "A patient developed an interstitial pneumonitis while receiving chlorambucil for a chronic lymphocytic leukemia (cumulative dose, 8,340 mg)." | 1.29 | Chlorambucil-associated pneumonitis. ( Clauvel, JP; Couderc, LJ; Crestani, B; Frija, J; Israël-Biet, D; Jaccard, A, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McCune, WJ | 1 |
| Vallance, DK | 1 |
| Lynch, JP | 1 |
| Mohr, M | 1 |
| Kingreen, D | 1 |
| Rühl, H | 1 |
| Huhn, D | 1 |
| Crestani, B | 1 |
| Jaccard, A | 1 |
| Israël-Biet, D | 1 |
| Couderc, LJ | 1 |
| Frija, J | 1 |
| Clauvel, JP | 1 |
| Tomlinson, J | 1 |
| Tighe, M | 1 |
| Johnson, S | 1 |
| Stone, R | 1 |
| Nicholson, AG | 1 |
| Rule, S | 1 |
2 reviews available for chlorambucil and Lung Diseases, Interstitial
| Article | Year |
|---|---|
Immunosuppressive drug therapy.
Topics: Adrenal Cortex Hormones; Azathioprine; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Cyc | 1994 |
Interstitial lung disease--an underdiagnosed side effect of chlorambucil?
Topics: Chlorambucil; Humans; Interferon Type I; Leukemia, Lymphocytic, Chronic, B-Cell; Lung Diseases, Inte | 1993 |
2 other studies available for chlorambucil and Lung Diseases, Interstitial
| Article | Year |
|---|---|
Chlorambucil-associated pneumonitis.
Topics: Alveolitis, Extrinsic Allergic; Bronchoalveolar Lavage Fluid; Chlorambucil; Humans; Leukemia, Lympho | 1994 |
Interstitial pneumonitis following mitozantrone, chlorambucil and prednisolone (MCP) chemotherapy.
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Female; H | 1999 |