chlorambucil has been researched along with Leukostasis in 1 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Leukostasis: Abnormal intravascular leukocyte aggregation and clumping often seen in leukemia patients. The brain and lungs are the two most commonly affected organs. This acute syndrome requires aggressive cytoreductive modalities including chemotherapy and/or leukophoresis. It is differentiated from LEUKEMIC INFILTRATION which is a neoplastic process where leukemic cells invade organs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leukostasis is a medical emergency requiring intensive care unit (ICU) admission and its management includes aggressive hydration, prevention and treatment of tumor lysis syndrome, cytoreduction, and leukapheresis." | 1.56 | Leukostasis in Chronic Lymphocytic Leukemia. ( Dabrowski, L; Sidhu, G; Singh Lubana, S; Singh, N, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Singh, N | 1 |
| Singh Lubana, S | 1 |
| Dabrowski, L | 1 |
| Sidhu, G | 1 |
1 other study available for chlorambucil and Leukostasis
| Article | Year |
|---|---|
Leukostasis in Chronic Lymphocytic Leukemia.
Topics: Aged; Antineoplastic Agents, Alkylating; Chlorambucil; Cough; Dyspnea; Female; Humans; Leukapheresis | 2020 |