Page last updated: 2024-10-24

chlorambucil and Leukocytopenia

chlorambucil has been researched along with Leukocytopenia in 48 studies

Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.

Research Excerpts

ExcerptRelevanceReference
"Five patients with a steroid-responsive, frequently relapsing nephrotic syndrome who had failed at least one course of treatment with cyclophosphamide were all put into a long term remission with chlorambucil."7.67Remission induced by chlorambucil in steroid-responsive, frequently relapsing nephrotic syndrome that relapsed after cyclophosphamide. ( Bailey, RR, 1989)
"Our clinical experience in 28 patients receiving chlorambucil for rheumatoid arthritis (RA) and the reports on chlorambucil therapy are reviewed."7.67Chlorambucil therapy in rheumatoid arthritis: clinical experience in 28 patients and literature review. ( Cannon, GW; Clegg, DO; Jackson, CG; Samuelson, CO; Ward, JR; Williams, HJ, 1985)
"The therapeutic effect of prednimustine was studied in 35 patients with advanced breast cancer resistant to previous cytotoxic and/or endocrine therapy."7.66Phase II trial of prednimustine, L-1031, (NSC-134087) in advanced breast cancer. ( Dombernowsky, P; Kristensen, D; Mouridsen, HT; Nielsen, JH, 1980)
" Although multi-drug therapy is known to produce myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) in patients with CTD, treatment with single-agent therapy, particularly methotrexate, has rarely been associated with secondary MDS or AML."3.69Myelodysplastic syndromes and acute myeloid leukemia in connective tissue disease after single-agent chemotherapy. ( Farhi, DC; Rosenthal, NS, 1996)
"Five patients with a steroid-responsive, frequently relapsing nephrotic syndrome who had failed at least one course of treatment with cyclophosphamide were all put into a long term remission with chlorambucil."3.67Remission induced by chlorambucil in steroid-responsive, frequently relapsing nephrotic syndrome that relapsed after cyclophosphamide. ( Bailey, RR, 1989)
"Our clinical experience in 28 patients receiving chlorambucil for rheumatoid arthritis (RA) and the reports on chlorambucil therapy are reviewed."3.67Chlorambucil therapy in rheumatoid arthritis: clinical experience in 28 patients and literature review. ( Cannon, GW; Clegg, DO; Jackson, CG; Samuelson, CO; Ward, JR; Williams, HJ, 1985)
"The therapeutic effect of prednimustine was studied in 35 patients with advanced breast cancer resistant to previous cytotoxic and/or endocrine therapy."3.66Phase II trial of prednimustine, L-1031, (NSC-134087) in advanced breast cancer. ( Dombernowsky, P; Kristensen, D; Mouridsen, HT; Nielsen, JH, 1980)
"Patients with biopsy-proven membranous nephropathy and with a nephrotic syndrome were randomized to be given methylprednisolone (1 g intravenously for 3 consecutive days followed by oral methylprednisolone, 0."2.69A randomized study comparing methylprednisolone plus chlorambucil versus methylprednisolone plus cyclophosphamide in idiopathic membranous nephropathy. ( Altieri, P; Antonucci, F; Bellazzi, R; Cesana, B; Dugo, M; Farina, M; Grassi, C; Lupo, A; Melis, P; Minari, M; Pasquali, S; Passerini, P; Pedrini, L; Piccoli, G; Pisano, G; Ponticelli, C; Pozzi, C; Roccatello, D; Sasdelli, M; Scalia, A; Scolari, F; Segagni, S; Valzorio, B, 1998)
"Low-grade B-cell MALT lymphoma was diagnosed by histologic and immunohistologic examination of endoscopic biopsies."1.29Efficacy of single-agent chemotherapy in low-grade B-cell mucosa-associated lymphoid tissue lymphoma with prominent gastric expression. ( Chaumette, MT; Delchier, JC; Divine, M; Gaulard, P; Haioun, C; Hammel, P; Reyes, F, 1995)
"One characteristic of experimental allergic encephalomyelitis (EAE) in all species is the presence of a considerable leukocyte infiltrate in the central nervous system (CNS)."1.27Experimental allergic encephalomyelitis in the absence of a classical delayed-type hypersensitivity reaction. Severe paralytic disease correlates with the presence of interleukin 2 receptor-positive cells infiltrating the central nervous system. ( Brostoff, S; Mason, D; Sedgwick, J, 1987)
" With long-term administration (the longest term, 20 weeks, 36 patients), the dose-limiting factor was concluded to be a decrease in the peripheral leukocyte count when the total amount administered reached about 10 g."1.27[Phase I study of bestrabucil (KM 2210)]. ( Agatsuma, T; Fugiwara, A; Fujita, K; Goto, T; Isurugi, K; Kamei, H; Kubota, T; Nakao, I; Suga, S; Takenaka, K, 1986)
" The patients were divided into three groups according to dosage and previous treatment."1.26Continuous treatment of non-Hodgkin's malignant lymphoma with prednimustine (Leo 1031). ( Håkansson, L; Könyves, I; Lindberg, LG; Möller, T, 1978)
" Each case was associated with prior chlorambucil administration, effective in controlling the clinical manifestations (total dosage 398 and 1,764 mg respectively)."1.25Irreversible bone marrow failure with chlorambucil. ( Epstein, WV; Fries, JF; Rudd, P, 1975)

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-199043 (89.58)18.7374
1990's4 (8.33)18.2507
2000's1 (2.08)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Knauf, W1
EISMAN, SG1
RICHARDSON, FM1
Brunner, KW1
Vugrin, D1
Whitmore, WF1
Golbey, RB1
Krel', AA2
Kanevskaia, MZ2
Rashchupkina, ZP1
Bolotin, EV2
Chichasova, NV1
Golomb, HM1
Schmidt, K1
Vardiman, JW1
Waibel, PJ1
Jungi, WF1
Senn, HJ1
Rørth, M1
Løber, J1
Dombernowsky, P2
Krusenstjerna-Hofstrom, D1
Mattsson, W1
Mouridsen, HT2
Pascual, JF1
Molina, M1
Lopez, J1
Kristensen, D1
Nielsen, JH1
Hammel, P1
Haioun, C1
Chaumette, MT1
Gaulard, P1
Divine, M1
Reyes, F1
Delchier, JC1
Rosenthal, NS1
Farhi, DC1
Ponticelli, C1
Altieri, P1
Scolari, F1
Passerini, P1
Roccatello, D1
Cesana, B1
Melis, P1
Valzorio, B1
Sasdelli, M1
Pasquali, S1
Pozzi, C1
Piccoli, G1
Lupo, A1
Segagni, S1
Antonucci, F1
Dugo, M1
Minari, M1
Scalia, A1
Pedrini, L1
Pisano, G1
Grassi, C1
Farina, M1
Bellazzi, R1
Trifonov, IuI1
Håkansson, L1
Könyves, I1
Lindberg, LG1
Möller, T1
Renier, JC2
Bregeon, C2
Bonnette, C1
Miller, SP1
Brenner, S1
Horton, J1
Stolbach, L1
Shnider, BI1
Pocock, S1
Cziráki, L1
Oó, M1
Dinning, WJ1
Perkins, ES1
Rudd, P1
Fries, JF1
Epstein, WV2
Rankin, EM1
Mill, L1
Kaye, SB1
Atkinson, R1
Cassidy, L1
Cordiner, J1
Cruickshank, D1
Davis, J2
Duncan, ID1
Fullerton, W1
Sedgwick, J1
Brostoff, S1
Mason, D1
Bailey, RR1
Clements, PJ1
Nagura, E1
Ohno, R1
Yamada, K1
Akao, Y1
Naito, K1
Nishikawa, M1
Tanaka, H1
Shirakawa, S1
Ono, Y1
Ezaki, K1
Kamei, H1
Takenaka, K1
Goto, T1
Suga, S1
Fugiwara, A1
Nakao, I1
Agatsuma, T1
Fujita, K1
Isurugi, K1
Kubota, T1
Cannon, GW1
Jackson, CG1
Samuelson, CO1
Ward, JR1
Williams, HJ1
Clegg, DO1
Cameron, JS1
Boulton-Jones, M1
Robinson, R1
Ogg, C1
Stacher, A1
Grupe, WE1
Desser, RK1
Ultmann, JE1
Thumb, N1
Horak, W1
Godfrey, WA1
O'Connor, GR1
Kimura, SJ1
Hogan, MJ1
Nozik, RA1
Brodehl, J1
Linshaw, MA1
Gruskin, AB1
Kaung, DT1
Wittington, RM1
Spencer, H1
Patno, ME2
Senyszyn, JJ1
Johnson, RE1
Curran, RE1
Saslaw, S1
Carlisle, HN1
Ansfield, FJ1
Carter, AC1
Goldenberg, IS1
Segaloff, A1
Cayla, J1
Rondier, J1
Deshayes, P1
Houdent, G1
Marcus, SL1
Larbi, SO1
Philp, RB1
Gowdey, CW1
Aschkenasy, A1
Green, RA1
Humphrey, E1
Close, H1
Lévèque, B1
Debauchez, C1
Deflandre, L1
Marie, J1
Bross, ID1
Rimm, AA1
Slack, NH1
Ausman, RK1
Jones, R1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Clinical Study of Rituximab or Cyclophosphamide Combined With Steroids in the Treatment of Idiopathic Membranous Nephropathy[NCT05514015]Phase 472 participants (Anticipated)Interventional2022-08-25Not yet recruiting
Random, Open, Control and Monocentric Clinical Research on Tacrolimus Monotherapy for Idiopathic Membranous Nephropathy (IMN)[NCT03549663]108 participants (Anticipated)Interventional2018-07-04Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for chlorambucil and Leukocytopenia

ArticleYear
Bendamustine in the treatment of chronic lymphocytic leukemia.
    Expert review of anticancer therapy, 2009, Volume: 9, Issue:2

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochlo

2009
Cytotoxic drugs: their clinical application to the rheumatic diseases.
    Seminars in arthritis and rheumatism, 1986, Volume: 15, Issue:4

    Topics: Arthritis; Arthritis, Rheumatoid; Azathioprine; Behcet Syndrome; Bone Marrow; Cell Division; Chemica

1986
The sensitivity of Hodgkin's disease to chemotherapeutic agents administered singly.
    Series haematologica (1968), 1973, Volume: 6, Issue:2

    Topics: Adrenal Cortex Hormones; Alopecia; Antineoplastic Agents; Bleomycin; Blood Platelet Disorders; Carmu

1973
[Immunosuppressive therapy of the nephrotic syndrome in childhood].
    Monatsschrift fur Kinderheilkunde, 1972, Volume: 120, Issue:6

    Topics: Azathioprine; Child; Chlorambucil; Cyclophosphamide; Cystitis; Drug Resistance; Humans; Immunosuppre

1972
Management of the nephrotic syndrome.
    Clinical pediatrics, 1974, Volume: 13, Issue:1

    Topics: Adolescent; Azathioprine; Child; Child, Preschool; Chlorambucil; Clinical Trials as Topic; Cyclophos

1974

Trials

9 trials available for chlorambucil and Leukocytopenia

ArticleYear
A phase III study of prednimustine (LEO 1031) in advanced breast cancer. A preliminary report.
    European journal of cancer, 1980, Volume: Suppl 1

    Topics: Adult; Aged; Breast Neoplasms; Chlorambucil; Clinical Trials as Topic; Drug Therapy, Combination; Fe

1980
A randomized study comparing methylprednisolone plus chlorambucil versus methylprednisolone plus cyclophosphamide in idiopathic membranous nephropathy.
    Journal of the American Society of Nephrology : JASN, 1998, Volume: 9, Issue:3

    Topics: Adolescent; Adult; Aged; Amenorrhea; Anemia; Antineoplastic Agents, Alkylating; Carcinoma; Chlorambu

1998
A randomized study comparing methylprednisolone plus chlorambucil versus methylprednisolone plus cyclophosphamide in idiopathic membranous nephropathy.
    Journal of the American Society of Nephrology : JASN, 1998, Volume: 9, Issue:3

    Topics: Adolescent; Adult; Aged; Amenorrhea; Anemia; Antineoplastic Agents, Alkylating; Carcinoma; Chlorambu

1998
A randomized study comparing methylprednisolone plus chlorambucil versus methylprednisolone plus cyclophosphamide in idiopathic membranous nephropathy.
    Journal of the American Society of Nephrology : JASN, 1998, Volume: 9, Issue:3

    Topics: Adolescent; Adult; Aged; Amenorrhea; Anemia; Antineoplastic Agents, Alkylating; Carcinoma; Chlorambu

1998
A randomized study comparing methylprednisolone plus chlorambucil versus methylprednisolone plus cyclophosphamide in idiopathic membranous nephropathy.
    Journal of the American Society of Nephrology : JASN, 1998, Volume: 9, Issue:3

    Topics: Adolescent; Adult; Aged; Amenorrhea; Anemia; Antineoplastic Agents, Alkylating; Carcinoma; Chlorambu

1998
[Results of immunosuppressive therapy in 78 patients with rheumatoid polyarthritis, treated for at least 4 years].
    Revue du rhumatisme et des maladies osteo-articulaires, 1975, Volume: 42, Issue:6

    Topics: Adrenal Cortex Hormones; Adult; Aged; Arthritis, Rheumatoid; Blood Sedimentation; Chlorambucil; Clin

1975
Comparative evaluation of combined radiation-chlorambucil treatment of ovarian carcinomatosis.
    Cancer, 1975, Volume: 36, Issue:5

    Topics: Chlorambucil; Digestive System; Evaluation Studies as Topic; Female; Humans; Leukopenia; Ovarian Neo

1975
A randomised study comparing standard dose carboplatin with chlorambucil and carboplatin in advanced ovarian cancer.
    British journal of cancer, 1992, Volume: 65, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chlorambucil; Drug Adminis

1992
Management of the nephrotic syndrome.
    Clinical pediatrics, 1974, Volume: 13, Issue:1

    Topics: Adolescent; Azathioprine; Child; Child, Preschool; Chlorambucil; Clinical Trials as Topic; Cyclophos

1974
Comparison of chlorambucil and streptonigrin (NSC-45383) in the treatment of malignant lymphomas.
    Cancer, 1969, Volume: 23, Issue:6

    Topics: Antibiotics, Antineoplastic; Bone Marrow; Chlorambucil; Clinical Trials as Topic; Digestive System;

1969
Treatment of metastatic Ewing's sarcoma with actinomycin D (NSC-3053).
    Cancer chemotherapy reports, 1970, Volume: 54, Issue:2

    Topics: Adolescent; Adult; Child; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Dactinomycin; Hu

1970
Alkylating agents in bronchogenic carcinoma.
    The American journal of medicine, 1969, Volume: 46, Issue:4

    Topics: Adenocarcinoma; Alkylating Agents; Carcinoma; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Chl

1969

Other Studies

35 other studies available for chlorambucil and Leukocytopenia

ArticleYear
CANCER CHEMOTHERAPY.
    Medical science, 1964, Volume: 15

    Topics: Adrenal Cortex Hormones; Aminopterin; Androgens; Antimetabolites; Antineoplastic Agents; Blood Plate

1964
[Therapy of plasmocytoma].
    Deutsche medizinische Wochenschrift (1946), 1967, Aug-25, Volume: 92, Issue:34

    Topics: Anemia; Blood Protein Disorders; Chlorambucil; Humans; Hypercalcemia; Leukopenia; Melphalan; Plasmac

1967
VAB-5 combination chemotherapy in prognostically poor risk patients with germ cell tumors.
    Cancer, 1983, Mar-15, Volume: 51, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisp

1983
[Chlorbutin, azathioprine, D-penicillamine, and levamisole (Decaris) in the treatment of rheumatoid arthritis patients. I. Comparative analysis of side effects].
    Terapevticheskii arkhiv, 1981, Volume: 53, Issue:7

    Topics: Arthritis, Rheumatoid; Azathioprine; Bronchial Spasm; Chlorambucil; Drug Eruptions; Dyspepsia; Human

1981
Chlorambucil therapy of twenty-four postsplenectomy patients with progressive hairy cell leukemia.
    Seminars in oncology, 1984, Volume: 11, Issue:4 Suppl 2

    Topics: Chlorambucil; Follow-Up Studies; Humans; Leukemia, Hairy Cell; Leukopenia; Splenectomy

1984
[Chemotherapy of metastasizing breast cancer. Adriamycin mono and combination therapy after LMFP pretreatment].
    Deutsche medizinische Wochenschrift (1946), 1983, Dec-02, Volume: 108, Issue:48

    Topics: Alopecia; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chlorambucil; Cyclophosp

1983
Long-term assessment of chlorambucil in children with nephrotic syndrome who fail to respond adequately to corticosteroids.
    Contributions to nephrology, 1981, Volume: 27

    Topics: Adolescent; Anemia; Bacterial Infections; Child; Child, Preschool; Chlorambucil; Drug Resistance; Fe

1981
Phase II trial of prednimustine, L-1031, (NSC-134087) in advanced breast cancer.
    Cancer, 1980, Jul-15, Volume: 46, Issue:2

    Topics: Adult; Aged; Breast Neoplasms; Chlorambucil; Drug Evaluation; Female; Humans; Leukopenia; Middle Age

1980
Efficacy of single-agent chemotherapy in low-grade B-cell mucosa-associated lymphoid tissue lymphoma with prominent gastric expression.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:10

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Chlorambuci

1995
Myelodysplastic syndromes and acute myeloid leukemia in connective tissue disease after single-agent chemotherapy.
    American journal of clinical pathology, 1996, Volume: 106, Issue:5

    Topics: Acute Disease; Adult; Aged; Antigens, CD; Antirheumatic Agents; Chlorambucil; Connective Tissue Dise

1996
[Cytopenic syndrome in rheumatoid arthritis patients treated with leukeran and azathioprine].
    Sovetskaia meditsina, 1979, Issue:9

    Topics: Adult; Aged; Arthritis, Rheumatoid; Azathioprine; Chlorambucil; Female; Humans; Leukopenia; Male; Mi

1979
Continuous treatment of non-Hodgkin's malignant lymphoma with prednimustine (Leo 1031).
    Oncology, 1978, Volume: 35, Issue:3

    Topics: Adult; Aged; Chlorambucil; Female; Humans; Leukopenia; Lymphoma; Male; Middle Aged; Prednisolone; Th

1978
[Combined leukeran-prednisolone therapy in metastasizing breast cancer].
    Fortschritte der Medizin, 1977, Apr-21, Volume: 95, Issue:15

    Topics: Adenocarcinoma; Adult; Aged; Breast Neoplasms; Chlorambucil; Drug Therapy, Combination; Female; Huma

1977
Clinical conference: Mixed cryoimmunoglobulinemia.
    The American journal of medicine, 1976, Volume: 61, Issue:1

    Topics: Chlorambucil; Cryoglobulins; Female; Humans; Immunoglobulin G; Immunoglobulin M; Leukopenia; Lung; L

1976
Immunosuppressives in uveitis. A preliminary report of experience with chlorambucil.
    The British journal of ophthalmology, 1975, Volume: 59, Issue:8

    Topics: Adult; Behcet Syndrome; Chlorambucil; Endophthalmitis; Female; Follow-Up Studies; Humans; Leukopenia

1975
Irreversible bone marrow failure with chlorambucil.
    The Journal of rheumatology, 1975, Volume: 2, Issue:4

    Topics: Adolescent; Anemia, Aplastic; Arthritis, Rheumatoid; Bone Marrow; Chlorambucil; Female; Humans; Leuk

1975
Experimental allergic encephalomyelitis in the absence of a classical delayed-type hypersensitivity reaction. Severe paralytic disease correlates with the presence of interleukin 2 receptor-positive cells infiltrating the central nervous system.
    The Journal of experimental medicine, 1987, Apr-01, Volume: 165, Issue:4

    Topics: Animals; Busulfan; Cells, Cultured; Central Nervous System; Cerebral Hemorrhage; Chlorambucil; Encep

1987
Remission induced by chlorambucil in steroid-responsive, frequently relapsing nephrotic syndrome that relapsed after cyclophosphamide.
    The New Zealand medical journal, 1989, Jul-26, Volume: 102, Issue:872

    Topics: Administration, Oral; Child; Chlorambucil; Cyclophosphamide; Drug Administration Schedule; Drug Eval

1989
[Early phase II trial of bestrabucil in hematological malignancies].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:6

    Topics: Adult; Aged; Chlorambucil; Drug Administration Schedule; Drug Evaluation; Estradiol; Female; Humans;

1986
[Phase I study of bestrabucil (KM 2210)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:6

    Topics: Adult; Aged; Animals; Anorexia; Chlorambucil; Dose-Response Relationship, Drug; Drug Administration

1986
Chlorambucil therapy in rheumatoid arthritis: clinical experience in 28 patients and literature review.
    Seminars in arthritis and rheumatism, 1985, Volume: 15, Issue:2

    Topics: Adult; Arthritis, Rheumatoid; Chlorambucil; Drug Evaluation; Female; Humans; Leukemia, Myeloid, Acut

1985
Treatment of lupus nephritis with cyclophosphamide.
    Lancet (London, England), 1970, Oct-24, Volume: 2, Issue:7678

    Topics: Adolescent; Adult; Age Factors; Azathioprine; Biopsy; Chlorambucil; Cortisone; Cyclophosphamide; Fem

1970
[Immunosuppressive therapy in hematology].
    Folia haematologica (Leipzig, Germany : 1928), 1972, Volume: 97, Issue:3

    Topics: Adrenal Cortex Hormones; Adult; Anemia, Aplastic; Anemia, Hemolytic, Autoimmune; Anemia, Myelophthis

1972
Chlorambucil in steroid-dependent nephrotic syndrome.
    The Journal of pediatrics, 1973, Volume: 82, Issue:4

    Topics: Adolescent; Beta-Globulins; Blood Pressure; Child; Child, Preschool; Chlorambucil; Drug Synergism; F

1973
[Therapy with chlorambucil in progressive chronic polyarthritis].
    Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete, 1968, Volume: 49, Issue:12

    Topics: Aged; Arthritis, Rheumatoid; Blood Sedimentation; Chlorambucil; Chronic Disease; Female; gamma-Globu

1968
The use of chlorambucil in intractable idiopathic uveitis.
    American journal of ophthalmology, 1974, Volume: 78, Issue:3

    Topics: Adolescent; Arthritis, Rheumatoid; Behcet Syndrome; Blood Cell Count; Blood Platelets; Chemical Phen

1974
Nonhuman primates in evaluation of hematotoxicity.
    Annals of the New York Academy of Sciences, 1969, Jul-03, Volume: 162, Issue:1

    Topics: Animals; Busulfan; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug-Related Side Effects and Adver

1969
Phase I study of phenesterin (NSC-104469).
    Cancer chemotherapy reports, 1971, Volume: 55, Issue:3

    Topics: Administration, Oral; Adult; Aged; Androgens; Antineoplastic Agents; Blood Cell Count; Blood Platele

1971
[Treatment of 67 rheumatoid polyarthritis cases with chlorambucil].
    Revue du rhumatisme et des maladies osteo-articulaires, 1971, Volume: 38, Issue:12

    Topics: Adult; Age Factors; Aged; Amenorrhea; Arthritis, Rheumatoid; Bacterial Infections; Blood Cell Count;

1971
[Complications and sequelae of immunosuppressive therapy of rheumatoid arthritis].
    Revue du rhumatisme et des maladies osteo-articulaires, 1971, Volume: 38, Issue:12

    Topics: Alopecia; Amenorrhea; Anemia; Arthritis, Rheumatoid; Bacterial Infections; Chlorambucil; Cyclophosph

1971
Effect of induced leukopenia on the contraceptive action of an intrauterine device in the rat.
    Obstetrics and gynecology, 1971, Volume: 38, Issue:1

    Topics: Animals; Chlorambucil; Contraception; Embryo Implantation; Endometrium; Exudates and Transudates; Fe

1971
The effects of alkoxyglycerols on haematopoiesis.
    Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 173, Issue:1

    Topics: Anemia; Animals; Benzene; Blood Cell Count; Busulfan; Chlorambucil; Erythrocyte Count; Female; Hemat

1968
[Effects of casein on the regeneration of blood neutrophils and lymphocytes in rats injected with a radiomimetic agent (chlorambucil) and depleted of proteins. A possible immunologic mechanism for the lymphopoietic effect of ingested proteins].
    Revue francaise d'etudes cliniques et biologiques, 1968, Volume: 13, Issue:8

    Topics: Animals; Antigen-Antibody Reactions; Caseins; Chlorambucil; Diet; Hematopoiesis; Leukocyte Count; Le

1968
[Chlorambucil in the treatment of idiopathic nephrotic syndrome without glomrular lesions in childhood. Apropos of 30 cases].
    Annales de pediatrie, 1969, Jan-02, Volume: 16, Issue:1

    Topics: Adolescent; Anemia; Biopsy; Child; Child, Preschool; Chlorambucil; Female; Glucocorticoids; Humans;

1969
Is toxicity really necessary? II. Source and analysis of data.
    Cancer, 1966, Volume: 19, Issue:12

    Topics: Alkylating Agents; Carbamates; Chlorambucil; Fluorouracil; Humans; Leukocyte Count; Leukopenia; Merc

1966