chlorambucil has been researched along with Leukemic Infiltration in 8 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Leukemic Infiltration: A pathologic change in leukemia in which leukemic cells permeate various organs at any stage of the disease. All types of leukemia show various degrees of infiltration, depending upon the type of leukemia. The degree of infiltration may vary from site to site. The liver and spleen are common sites of infiltration, the greatest appearing in myelocytic leukemia, but infiltration is seen also in the granulocytic and lymphocytic types. The kidney is also a common site and of the gastrointestinal system, the stomach and ileum are commonly involved. In lymphocytic leukemia the skin is often infiltrated. The central nervous system too is a common site.
Excerpt | Relevance | Reference |
---|---|---|
"Treatment with chlorambucil, prednisolone, and renal bed irradiation resulted in a substantial improvement in renal function which persisted until the the patient's death from marrow failure some eight years later." | 1.29 | Renal failure caused by leukaemic infiltration in chronic lymphocytic leukaemia. ( Bass, PS; Davies, DR; Jones, NF; Majumdar, G; Pearson, TC; Phillips, JK, 1993) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (12.50) | 18.2507 |
2000's | 4 (50.00) | 29.6817 |
2010's | 3 (37.50) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Kacem, K | 1 |
Zriba, S | 1 |
Saadi, M | 1 |
Doghri, R | 1 |
Streu, E | 1 |
Hapgood, G | 1 |
Mooney, E | 1 |
Dinh, HV | 1 |
Gin, D | 1 |
McLean, C | 1 |
Ting, SB | 1 |
Aktan, M | 1 |
Akkaya, A | 1 |
Doğan, O | 1 |
Dincol, G | 1 |
Kalac, M | 1 |
Suvic-Krizanic, V | 1 |
Ostojic, S | 1 |
Kardum-Skelin, I | 1 |
Barsic, B | 1 |
Jaksica, B | 1 |
Sureda, NC | 1 |
Bosch, MP | 1 |
Kurpis, M | 1 |
Ruiz Lascano, A | 1 |
Phillips, JK | 1 |
Bass, PS | 1 |
Majumdar, G | 1 |
Davies, DR | 1 |
Jones, NF | 1 |
Pearson, TC | 1 |
Várkonyi, J | 1 |
Zalatnai, A | 1 |
Timár, J | 1 |
Matolcsi, A | 1 |
Falus, A | 1 |
Bencsáth, M | 1 |
László, V | 1 |
Pócsik, E | 1 |
Kotlán, B | 1 |
Császár, A | 1 |
8 other studies available for chlorambucil and Leukemic Infiltration
Article | Year |
---|---|
Gingival Leukemic Infiltration in Chronic Lymphocytic Leukemia
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Female; Humans; Leukemia, Lympho | 2019 |
Second malignancies in chronic lymphocytic leukemia.
Topics: Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Carcin | 2014 |
Leukaemia cutis in chronic lymphocytic leukaemia following varicella zoster virus reactivation.
Topics: Aged; Antineoplastic Agents, Alkylating; Chlorambucil; Disease Progression; Herpes Zoster; Humans; L | 2012 |
Chronic lymphocytic leukemia and multiple myeloma in the same patient: case report.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Bone Neoplasms; Chlorambucil; C | 2003 |
Central nervous system involvement of previously undiagnosed chronic lymphocytic leukemia in a patient with neuroborreliosis.
Topics: Anti-Infective Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Blood-Bra | 2007 |
[Leukaemia cutis: clinical manifestation of chronic lymphocytic leukaemia relapse].
Topics: Aged; Antineoplastic Agents, Alkylating; Biopsy; Chlorambucil; Humans; Leukemia, Lymphocytic, Chroni | 2007 |
Renal failure caused by leukaemic infiltration in chronic lymphocytic leukaemia.
Topics: Chlorambucil; Combined Modality Therapy; Humans; Kidney; Kidney Failure, Chronic; Leukemia, Lymphocy | 1993 |
Secondary cutaneous infiltration in B cell chronic lymphocytic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Doxorubicin; Histidi | 2000 |