chlorambucil has been researched along with Leukemia, Monocytic, Acute in 7 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Leukemia, Monocytic, Acute: An acute myeloid leukemia in which 80% or more of the leukemic cells are of monocytic lineage including monoblasts, promonocytes, and MONOCYTES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We evaluated the occurrence of acute nonlymphocytic leukemia (ANL) among 1399 women with ovarian cancer who were treated in five randomized clinical trials." | 2.65 | Acute nonlymphocytic leukemia after therapy with alkylating agents for ovarian cancer: a study of five randomized clinical trials. ( Blessing, JA; Boice, JD; Dembo, AJ; Greene, MH; Greer, BE, 1982) |
| "THP-1, a cell line, derived from human acute monoblastic leukemia, was used." | 1.31 | Cytoprotective features of selenazofurin in hematopoietic cells. ( Hasmann, M; Nuessler, V; Pelka-Fleischer, R; Pogrebniak, A; Schemainda, I, 2002) |
| "A case of chronic lymphocytic leukemia (CLL) treated with chlorambucil, followed by the development of an acute monoblastic leukemia, is described." | 1.28 | Acute monocytic leukemia with B cell markers expression following B chronic lymphocytic leukemia. ( Assens, C; Breton, A; Charlier, D; Donadio, D; Emberger, JM; Lavabre-Bertrand, T; Murgue, B; Poncelet, P; Taib, J; Vendrell, JP, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (71.43) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pogrebniak, A | 1 |
| Hasmann, M | 1 |
| Schemainda, I | 1 |
| Pelka-Fleischer, R | 1 |
| Nuessler, V | 1 |
| Lebranchu, Y | 1 |
| Drucker, J | 1 |
| Nivet, H | 1 |
| Rolland, JC | 1 |
| Grenier, B | 1 |
| Lejars, O | 1 |
| Lamagnere, JP | 1 |
| Buriot, D | 1 |
| Greene, MH | 1 |
| Boice, JD | 1 |
| Greer, BE | 1 |
| Blessing, JA | 1 |
| Dembo, AJ | 1 |
| Juul, K | 1 |
| Sørensen, P | 1 |
| Pedersen-Bjergaard, J | 1 |
| Jensen, MK | 1 |
| Lennon, SV | 1 |
| Martin, SJ | 1 |
| Cotter, TG | 1 |
| Lavabre-Bertrand, T | 1 |
| Donadio, D | 1 |
| Breton, A | 1 |
| Taib, J | 1 |
| Charlier, D | 1 |
| Assens, C | 1 |
| Poncelet, P | 1 |
| Murgue, B | 1 |
| Vendrell, JP | 1 |
| Emberger, JM | 1 |
| Danieli, G | 1 |
2 trials available for chlorambucil and Leukemia, Monocytic, Acute
| Article | Year |
|---|---|
Acute nonlymphocytic leukemia after therapy with alkylating agents for ovarian cancer: a study of five randomized clinical trials.
Topics: Acute Disease; Adult; Aged; Alkylating Agents; Animals; Chlorambucil; Clinical Trials as Topic; Fema | 1982 |
Phase II trial of Prednimustine. Leo-1031 (NSC-134087) in acute non-lymphocytic leukemia.
Topics: Adult; Aged; Chlorambucil; Clinical Trials as Topic; Female; Humans; Leukemia, Erythroblastic, Acute | 1979 |
5 other studies available for chlorambucil and Leukemia, Monocytic, Acute
| Article | Year |
|---|---|
Cytoprotective features of selenazofurin in hematopoietic cells.
Topics: Antineoplastic Agents; Cell Death; Cell Line; Cell Survival; Chlorambucil; Dose-Response Relationshi | 2002 |
Acute monoblastic leukaemia in child receiving chlorambucil for juvenile rheumatoid arthritis.
Topics: Arthritis, Juvenile; Chlorambucil; Humans; Infant; Leukemia, Monocytic, Acute; Male | 1980 |
Dose-dependent induction of apoptosis in human tumour cell lines by widely diverging stimuli.
Topics: Calcium; Cell Membrane Permeability; Cell Survival; Chlorambucil; DNA Damage; Ethanol; Hot Temperatu | 1991 |
Acute monocytic leukemia with B cell markers expression following B chronic lymphocytic leukemia.
Topics: Aged; B-Lymphocytes; Chlorambucil; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Monocyt | 1989 |
[1973 treatment of acute leukemias].
Topics: Chlorambucil; Colchicine; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Dru | 1974 |