chlorambucil has been researched along with Leukemia, Lymphocytic in 255 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Prednimustine, a chlorambucil ester of prednisolone, was administered to 16 patients with non-Hodgkin lymphomata (NHL) and 14 patients with chronic lymphocytic leukaemia (CLL), all previously treated with steroids and alkylating agents." | 9.05 | Clinical trial of prednimustine, Leo-1031 (NSC-134087), in patients with non-Hodgkin lymphomata and chronic lymphocytic leukaemia previously treated with steroids and alkylating agents. ( Geisler, CH; Hansen, MM; Nissen, NI; Pedersen-Bjergaard, J, 1980) |
| "Forty patients with lymphocytic lymphoma were treated with escalating doses of chlorambucil biweekly starting at a dose of 0." | 7.66 | Biweekly chlorambucil treatment of lymphocytic lymphoma. ( Knospe, WH; Loeb, V, 1980) |
| "Fourty-three of 61 patients suffering from low-grade malignant non-Hodgkin's lymphomas according to the Kiel classification were subjected to an intermittent combination chemotherapy with chlorambucil and prednisone." | 7.66 | Intermittent combination chemotherapy with chlorambucil and prednisone of low-grade malignant non-Hodgkin's lymphomas according to the Kiel classification. ( Garbrecht, M; Stolzenbach, G, 1979) |
| "Prednimustine, a chlorambucil ester of prednisolone, was administered to 16 patients with non-Hodgkin lymphomata (NHL) and 14 patients with chronic lymphocytic leukaemia (CLL), all previously treated with steroids and alkylating agents." | 5.05 | Clinical trial of prednimustine, Leo-1031 (NSC-134087), in patients with non-Hodgkin lymphomata and chronic lymphocytic leukaemia previously treated with steroids and alkylating agents. ( Geisler, CH; Hansen, MM; Nissen, NI; Pedersen-Bjergaard, J, 1980) |
| "Ninety-six patients with advanced chronic lymphocytic leukemia (CLL) (Stage C; anemia and/or thrombocytopenia of nonimmune origin) were randomized to receive either chlorambucil (CLR) (0." | 5.05 | Treatment of chronic lymphocytic leukemia in advanced stages. A randomized trial comparing chlorambucil plus prednisone versus cyclophosphamide, vincristine, and prednisone. ( Alcalá, A; Bueno, J; Domingo, A; Ferrán, C; García-Conde, J; Giralt, M; Montserrat, E; Parody, R; Rubio, D; Sanz, MA, 1985) |
| "Forty patients with lymphocytic lymphoma were treated with escalating doses of chlorambucil biweekly starting at a dose of 0." | 3.66 | Biweekly chlorambucil treatment of lymphocytic lymphoma. ( Knospe, WH; Loeb, V, 1980) |
| "Fourty-three of 61 patients suffering from low-grade malignant non-Hodgkin's lymphomas according to the Kiel classification were subjected to an intermittent combination chemotherapy with chlorambucil and prednisone." | 3.66 | Intermittent combination chemotherapy with chlorambucil and prednisone of low-grade malignant non-Hodgkin's lymphomas according to the Kiel classification. ( Garbrecht, M; Stolzenbach, G, 1979) |
| "B-, T- and O-lymphocytes detected as EAC-, E- and non-rosette forming lymphocytes were investigated in venous blood in 49 patients with connective tissue diseases, psoriasis and chronic lymphogenous leukaemia (CLL) during treatment with either prednisone alone, prednisone and cytostatic agents or cytostatic agents alone." | 3.65 | Influence of prednisone and cytostatics on human blood B-, T- and O-lymphocytes in diseases. ( Jonsson, V, 1975) |
| "These included 4 cases of chronic lymphocytic leukemia (CLL), 5 cases of chronic myelogenous leukemia (CML), 5 cases of malignant lymphoma (ML) and 7 cases of multiple myeloma (MM)." | 2.66 | [Clinical trial of bestrabucil (KM 2210) on hematopoietic malignancies]. ( Katayama, N; Kita, K; Kobayashi, T; Matsuoka, N; Minami, N; Nishikawa, M; Ohno, T; Tanaka, H; Tomeoku, M; Uemura, Y, 1986) |
| "Patients with untreated chronic lymphocytic leukemia (CLL) received protocol treatment with 6 months of chlorambucil (CB) (30 mg/M2) and prednisone (P) (80 mg/d X 5) every 2 weeks." | 2.66 | Treatment of chronic lymphocytic leukemia using chlorambucil and prednisone with or without cycle-active consolidation chemotherapy. A Southeastern Cancer Study Group Trial. ( Bartolucci, AA; Huguley, CM; Johnson, L; Keller, JW; Knospe, WH; Omura, GA; Raney, M, 1986) |
| "46 ambulatory patients with chronic lymphocytic leukemia were treated with Prednimustine either continuously (daily or each other day 20 mg) or intermittently (daily 20 mg for 14 days, followed by a pause of 4 weeks)." | 2.64 | [Effect of Prednimustine (Leo 1031) in chronic lymphatic leukemia]. ( Böhnel, J; Lutz, D, 1977) |
| "Prednisone was common to all three schedules and was given daily in an initial dosage of 0." | 2.64 | Comparison of daily versus intermittent chlorambucil and prednisone therapy in the treatment of patients with chronic lymphocytic leukemia. ( Glidewell, O; Rai, KR; Sawitsky, A; Silver, RT, 1977) |
| "In the chronic lymphocytic leukemia group, 3/4 have had benefit." | 2.64 | Treatment of chronic lymphocytic leukemia and lymphosarcoma with a new chlorambucil ester of prednisolone (Leo 1031) (NSC-134087). ( Aungst, CW; Mittelman, A; Murphy, GP, 1975) |
| "Treatment with chlorambucil and prednisone administered orally over a 1." | 1.40 | Diagnosis and treatment of chronic lymphocytic leukemia in a bat-eared fox (Otocyon megalotis). ( Adkesson, MJ; Landolfi, JA; Langan, JN; Nevitt, BN; Wilson, R, 2014) |
| " Pharmacokinetic studies suggest decreased bioavailability with successive cycles, probably due to accelerated metabolism." | 1.32 | High dose chlorambucil in the treatment of lymphoid malignancies. ( Nicolle, A; Proctor, SJ; Summerfield, GP, 2004) |
| "The primary treatment in low-grade malignant lymphomas was a combination of chlorambucil and prednisone: in case of progression or therapeutic failure more aggressive schedules (COP, C-MOPP, HOP, CHOP, BACOP) were used." | 1.27 | [Results of cytostatic polychemotherapy in non-Hodgkin lymphomas]. ( Bliem, J; Denz, H; Hehenwarter, W; Huber, H; Kratzer, H; Michlmayr, G; Nitsche, D; Tschurtschenthaler, G, 1983) |
| "KM 2210 was thought to be an effective drug for CLL." | 1.27 | [KM 2210 therapy for chronic lymphocytic leukemia]. ( Fukayama, M; Ikebuchi, K; Kaise, M; Miwa, A; Mori, M; Murai, Y; Nakamura, N, 1983) |
| "Two cases of CLL and one each of follicular lymphoma and pseudolymphoma achieved partial remission." | 1.27 | [Phase II study of chlorambucil in patients with hematological malignancies]. ( Horikoshi, N; Imajoh, K; Inoue, K; Itoh, Y; Mukaiyama, T; Nagamine, D; Ogawa, M; Ozeki, H; Shinagawa, K, 1987) |
| " We conclude that PMN is effective for FL and CLL, and that in addition, it has an advantage in that its mild side effects allow long-term administration through outpatient clinics, so that the quality of life for patients is not impaired." | 1.27 | [Phase II study of prednimustine in follicular lymphoma and chronic lymphocytic leukemia]. ( Horikoshi, N; Imajou, K; Inoue, K; Ito, Y; Miyaoka, K; Mukaiyama, T; Nakamura, T; Ogawa, M; Ozeki, H; Ueno, K, 1987) |
| "The survival of 137 consecutive chronic lymphocytic leukemia patients, diagnosed between 1960 and 1982 and followed up at the Hematology Clinic of the Chaim Sheba Center, was correlated with demographic, clinical and laboratory data." | 1.27 | Survival and prognostic factors in chronic lymphocytic leukemia. ( Ben-Bassat, I; Blumstein, T; Modan, M; Pines, A; Ramot, B, 1987) |
| "In 56 patients with chronic lymphocytic leukemia the value of clinical staging and response to therapy were analyzed." | 1.26 | Response to therapy as prognostic factor in chronic lymphocytic leukemia. ( Burghouts, J; Prüst, E; van Lier, HJ, 1980) |
| "Prolymphocytic leukemia is characterized by marked splenomegaly, distinctive cellular morphologic characteristics, and a poor clinical course." | 1.26 | Treatment of prolymphocytic leukemia. ( Coleman, M; Hollister, D, 1982) |
| "Progressive and severe autoimmune hemolytic anemia developed in a patient with chronic lymphocytic leukemia (CLL) despite treatment with chlorambucil, high doses of corticosteroids and attempts to transfuse packed red blood cells." | 1.26 | Specific immunoadsorption of IgG antibody in a patient with chronic lymphocytic leukemia and autoimmune hemolytic anemia. A new form of therapy for the acute critical stage. ( Bassett, JG; Besa, EC; Cooper, DR; Idiculla, A; Joseph, RR; Ray, PK; Rhoads, JE; Swami, VK, 1981) |
| "In 16 of these (19." | 1.26 | Primary malignant neoplasms associated with chronic lymphocytic leukemia. ( Franchi, F; Monfardini, S; Rilke, F; Santoro, A, 1980) |
| "Chlorambucil has only rarely been implicated in this complication." | 1.26 | Fatal interstitial pneumonitis following high-dose intermittent chlorambucil therapy for chronic lymphocyte leukemia. ( Besa, EC; Joseph, RR; Justh, G; Lane, SD, 1981) |
| "The grounds for treating or not treating chronic lymphocytic leukemias (CLL) and chronic myelocytic leukemias (CML) are discussed in the light of results in recent years." | 1.26 | [When do we have to treat chronic leukemia?]. ( Maurice, PA, 1978) |
| "Chronic lymphocytic leukemia and chronic granulocytic leukemia vary considerably in their clinical features, laboratory findings, and therapy, but both generally have an ominous prognosis." | 1.26 | Managing chronic leukemias. ( Silverstein, MN, 1977) |
| "The diagnosis of lymphocytic leukemia was based on the finding of a large number of mature lymphocytes in the blood and bone marrow." | 1.26 | Hyperviscosity syndrome associated with lymphocytic leukemia in three dogs. ( Hayes, A; Hurvitz, AI; MacEwen, EG, 1977) |
| "Treatment with chlorambucil resulted in normalization of the peripheral blood smear, but the malignant infiltration of the bone marrow continued and manifested itself by appearance of new osteolytic lesions, though some of the old lesions underwent recalcification after treatment." | 1.26 | Macroglobulinemia of Waldenström associated with severe osteolytic lesions. ( Krausz, Y; Zlotnick, A, 1977) |
| "Forty patients with chronic lymphocytic leukemia have been treated with mediastinal irradiation." | 1.26 | The control of chronic lymphocytic leukemia with mediastinal irradiation. ( Blake, DD; Ferree, C; Raben, M; Richards, F; Spurr, CL, 1978) |
| "Chronic lymphocytic leukemia (CLL) is the commonest type of leukemia seen in Western countries." | 1.26 | Chronic lymphocytic leukemia. ( Moore, JO; Rundles, RW, 1978) |
| "A method of clinical staging of chronic lymphocytic leukemia (CLL) has been proposed which is based on the concept that CLL is a disease of progressive accumulation of nonfunctioning lymphocytes: stage O, bone marrow and blood lymphocytosis only; stage 1, lymphocytosis with enlarged nodes; stage II, lymphocytosis with enlarged spleen or liver or both; stage III, lymphocytosis with anemia; and stage IV:lymphocytosis with thrombocytopenia." | 1.25 | Clinical staging of chronic lymphocytic leukemia. ( Chanana, AD; Cronkite, EP; Levy, RN; Pasternack, BS; Rai, KR; Sawitsky, A, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 252 (98.82) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (0.78) | 29.6817 |
| 2010's | 1 (0.39) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nevitt, BN | 1 |
| Langan, JN | 1 |
| Adkesson, MJ | 1 |
| Landolfi, JA | 1 |
| Wilson, R | 1 |
| HANSEN, PB | 1 |
| LAMY, P | 1 |
| REMIGY, E | 1 |
| STEHLIN, H | 1 |
| LAWKOWICZ, W | 1 |
| BECALSKI, J | 1 |
| GALTON, DA | 2 |
| WILTSHAW, E | 2 |
| SZUR, L | 1 |
| DACIE, JV | 1 |
| SPRAGUE, CC | 1 |
| BIGLEY, RH | 1 |
| EVANS, AM | 1 |
| RIEKHOF, P | 1 |
| ROSS, ED | 1 |
| SETTLE, JA | 1 |
| TELFER, AB | 1 |
| BERRY, CZ | 1 |
| SCHREIBER, MM | 1 |
| SHAPIRO, SI | 1 |
| ADAMS, JL | 1 |
| WILLIAMS, HM | 1 |
| NIZET, A | 1 |
| FEIWEL, M | 1 |
| MUNRO, DD | 1 |
| GRIZZLE, JE | 1 |
| BURNINGHAM, RA | 1 |
| RESTREPO, A | 1 |
| PUGH, RP | 1 |
| BROWN, EB | 1 |
| SCHLOSSMAN, SF | 1 |
| KHURI, PD | 1 |
| LESSNER, HE | 1 |
| HARRINGTON, WJ | 1 |
| BOOTSMA, BK | 1 |
| WOODLIFF, HJ | 1 |
| MOLANDER, DW | 1 |
| LADUE, JS | 1 |
| COWLING, DC | 1 |
| QUAGLINO, D | 1 |
| HAYHOE, FG | 2 |
| KAUNG, DT | 3 |
| WHITTINGTON, RM | 3 |
| PATNO, ME | 3 |
| INNES, J | 1 |
| DUMA, RJ | 1 |
| BOYETT, JD | 1 |
| BEETHAM, WP | 1 |
| EZDINLI, EZ | 3 |
| STUTZMAN, L | 1 |
| SBARRA, AJ | 1 |
| SHIRLEY, W | 1 |
| SELVARAJ, RJ | 1 |
| IOUCHI, E | 1 |
| ROSENBAUM, E | 1 |
| GREEN, RA | 1 |
| DIXON, H | 1 |
| HENNEMANN, HH | 1 |
| MOESCHLIN, S | 1 |
| BRODY, JI | 1 |
| BEIZER, LH | 1 |
| PALLESCHI, M | 1 |
| LIBANSKY, J | 2 |
| CHUDOMEL, V | 1 |
| BRABEC, V | 1 |
| SOCHMAN, J | 1 |
| PERRONE, V | 1 |
| FAIELLA, A | 1 |
| ZARRILLI, D | 1 |
| CAJANO, A | 1 |
| RUNDLES, W | 1 |
| GRIZZLE, J | 1 |
| BONO, VH | 1 |
| JONSSON, U | 1 |
| HUGULEY, CM | 5 |
| CORLEY, CC | 1 |
| Nicolle, A | 1 |
| Proctor, SJ | 1 |
| Summerfield, GP | 1 |
| Musch, E | 1 |
| Loos, U | 1 |
| Alléra, A | 1 |
| Hügl, E | 1 |
| Pütz, I | 1 |
| Malek, M | 1 |
| Olmer, J | 1 |
| Carcassonne, Y | 1 |
| Sinks, LF | 1 |
| Shohat, B | 1 |
| Gitter, S | 1 |
| Lavie, D | 1 |
| Han, T | 5 |
| Sokal, JE | 3 |
| Kopeć, J | 2 |
| Sitarska, E | 3 |
| Leszko, B | 4 |
| Kiss, A | 1 |
| Jakó, J | 1 |
| Telek, B | 1 |
| Rák, K | 1 |
| Guthrie, TH | 1 |
| Schaadt, M | 1 |
| Plaumann, L | 1 |
| Diehl, V | 1 |
| Silber, R | 3 |
| Ifrah, N | 1 |
| Marie, JP | 1 |
| Zittoun, R | 1 |
| Gaynon, PS | 1 |
| Baum, ES | 1 |
| Krivit, W | 1 |
| Hammond, D | 1 |
| Ehrsson, H | 1 |
| Wallin, I | 1 |
| Simonsson, B | 2 |
| Hartvig, P | 1 |
| Oberg, G | 1 |
| Oloo, AJ | 1 |
| Ogada, TA | 1 |
| Pasqualini, T | 1 |
| Eridani, S | 1 |
| Parry, H | 1 |
| Glass, U | 1 |
| Greaves, M | 1 |
| Schreiber, ZA | 1 |
| Axelrod, MR | 1 |
| Abebe, LS | 1 |
| Grabarczyk, M | 1 |
| Kratzer, H | 1 |
| Hehenwarter, W | 1 |
| Denz, H | 1 |
| Bliem, J | 1 |
| Tschurtschenthaler, G | 1 |
| Nitsche, D | 1 |
| Huber, H | 1 |
| Michlmayr, G | 2 |
| Mori, M | 1 |
| Murai, Y | 1 |
| Miwa, A | 1 |
| Fukayama, M | 1 |
| Ikebuchi, K | 1 |
| Nakamura, N | 1 |
| Kaise, M | 1 |
| Hagmann, SG | 1 |
| Huhn, D | 1 |
| Burghouts, J | 1 |
| Prüst, E | 1 |
| van Lier, HJ | 1 |
| Bolognesi, G | 1 |
| Sølling, K | 1 |
| Nielsen, JL | 1 |
| Sølling, J | 1 |
| Ellegaard, J | 1 |
| Alfinito, F | 1 |
| Formisano, S | 1 |
| Rotoli, B | 1 |
| Freedman, ML | 1 |
| Dillman, RO | 1 |
| Shawler, DL | 1 |
| Sobol, RE | 1 |
| Collins, HA | 1 |
| Beauregard, JC | 1 |
| Wormsley, SB | 1 |
| Royston, I | 1 |
| Ideström, K | 1 |
| Kimby, E | 1 |
| Björkholm, M | 1 |
| Mellstedt, H | 1 |
| Engstedt, L | 1 |
| Gahrton, G | 1 |
| Johansson, B | 2 |
| Killander, D | 1 |
| Robérts, KH | 1 |
| Stalfelt, AM | 1 |
| Udén, AM | 1 |
| Wadman, B | 1 |
| Wählby, S | 1 |
| Müller, W | 1 |
| Brandis, M | 1 |
| Al-Hilali, MM | 1 |
| Edgcumbe, JO | 1 |
| Joyner, MV | 1 |
| Varadi, S | 1 |
| Vijaykumar, S | 1 |
| Hollister, D | 1 |
| Coleman, M | 1 |
| Ogawa, M | 3 |
| Wirthmüller, R | 1 |
| Gerhartz, H | 2 |
| Foa, R | 2 |
| Lauria, F | 2 |
| Catovsky, D | 2 |
| Pedersen-Bjergaard, J | 1 |
| Hansen, MM | 1 |
| Geisler, CH | 1 |
| Nissen, NI | 1 |
| Gallo, JH | 1 |
| Phadke, KP | 1 |
| Buchanan, JG | 1 |
| Rubin, P | 1 |
| Bennett, JM | 2 |
| Begg, C | 1 |
| Bozdech, MJ | 1 |
| Giunta, G | 1 |
| Sponza, E | 1 |
| Trevisan, R | 1 |
| Pitzus, E | 1 |
| Fitzgerald, RH | 1 |
| Wallace, KM | 1 |
| Baker, AS | 1 |
| Greco, MM | 1 |
| Jaksić, B | 1 |
| Vitale, B | 1 |
| Floiras, JL | 1 |
| Allain, D | 1 |
| Turpin, F | 1 |
| Besa, EC | 2 |
| Ray, PK | 1 |
| Swami, VK | 1 |
| Idiculla, A | 1 |
| Rhoads, JE | 1 |
| Bassett, JG | 1 |
| Joseph, RR | 2 |
| Cooper, DR | 1 |
| Nilsson, K | 1 |
| Michallet, M | 2 |
| Sotto, JJ | 2 |
| Moulin, JJ | 1 |
| Arvieux, J | 1 |
| Hollard, D | 2 |
| Santoro, A | 1 |
| Rilke, F | 1 |
| Franchi, F | 1 |
| Monfardini, S | 1 |
| Giralt, M | 2 |
| Knospe, WH | 3 |
| Loeb, V | 2 |
| Lane, SD | 1 |
| Justh, G | 1 |
| Lesesve, JF | 1 |
| Feugier, P | 1 |
| Lamy, T | 1 |
| Béné, MC | 1 |
| Grégoire, MJ | 1 |
| Lenormand, B | 1 |
| Loughran, T | 1 |
| Galbraith, RM | 1 |
| Eddleston, AL | 1 |
| Williams, R | 1 |
| Zuckerman, AJ | 1 |
| Holowiecki, J | 1 |
| Stella, B | 1 |
| Lutz, D | 2 |
| Krawczyk, M | 1 |
| Ogonovskiĭ, TM | 1 |
| Naysmith, A | 1 |
| Robson, RH | 1 |
| Fernandez, LA | 2 |
| MacSween, JM | 1 |
| Langley, GR | 1 |
| Sandler, RM | 1 |
| Gonsalkorale, M | 1 |
| Einhorn, LH | 1 |
| MacEwen, EG | 2 |
| Patnaik, AK | 1 |
| Wilkins, RJ | 1 |
| Enck, RE | 1 |
| Maurice, PA | 1 |
| Spanedda, R | 1 |
| Romanini, D | 1 |
| Cinotti, A | 1 |
| Silverstein, MN | 1 |
| Abbrederis, K | 1 |
| Schmalzl, F | 1 |
| Huber, C | 1 |
| Braunsteiner, H | 1 |
| Heilmann, E | 1 |
| Nordiek, R | 1 |
| Böhnel, J | 1 |
| Sawitsky, A | 4 |
| Rai, KR | 2 |
| Glidewell, O | 1 |
| Silver, RT | 1 |
| Hurvitz, AI | 1 |
| Hayes, A | 1 |
| Krausz, Y | 1 |
| Zlotnick, A | 1 |
| Stolzenbach, G | 1 |
| Garbrecht, M | 1 |
| Godard, P | 1 |
| Marty, JP | 1 |
| Michel, FB | 1 |
| McLean, A | 1 |
| Woods, RL | 1 |
| Farmer, P | 1 |
| Alberts, DS | 1 |
| Chang, SY | 1 |
| Chen, HS | 1 |
| Larcom, BJ | 1 |
| Jones, SE | 1 |
| Fuchs, R | 1 |
| Mey, U | 1 |
| Pirofsky, B | 1 |
| Richards, F | 2 |
| Spurr, CL | 2 |
| Ferree, C | 1 |
| Blake, DD | 2 |
| Raben, M | 2 |
| Fazekas, T | 1 |
| Bach, K | 1 |
| Tóth, S | 1 |
| Bodor, F | 1 |
| Rundles, RW | 1 |
| Moore, JO | 1 |
| Blomgren, H | 1 |
| Jondal, M | 1 |
| Binet, JL | 1 |
| Leporrier, M | 1 |
| Dighiero, G | 1 |
| Charron, D | 1 |
| D'Athis, P | 1 |
| Vaugier, G | 1 |
| Beral, HM | 1 |
| Natali, JC | 1 |
| Raphael, M | 1 |
| Nizet, B | 1 |
| Follezou, JY | 1 |
| Trepel, F | 2 |
| Schick, P | 3 |
| Hill, BH | 1 |
| Goldenberg, GJ | 1 |
| Gunz, FW | 1 |
| Migdalska, B | 1 |
| Hartwig, W | 1 |
| Pawelski, S | 1 |
| Jonsson, V | 1 |
| Tung, R | 1 |
| Quagliata, F | 1 |
| Conklyn, M | 1 |
| Gottesman, J | 1 |
| Hirschhorn, R | 1 |
| Salsano, F | 1 |
| Froland, SS | 1 |
| Natvig, JB | 1 |
| Mandelli, F | 1 |
| Aungst, CW | 3 |
| Mittelman, A | 1 |
| Murphy, GP | 1 |
| Rose, MS | 1 |
| Brandt, L | 1 |
| Kónyves, I | 1 |
| Móller, TR | 1 |
| Cronkite, EP | 1 |
| Chanana, AD | 1 |
| Levy, RN | 1 |
| Pasternack, BS | 1 |
| Diem, E | 1 |
| Ghose, T | 1 |
| Lee, CL | 1 |
| Faulkner, G | 1 |
| Lee, SH | 1 |
| Devilliers, E | 1 |
| Carli, PM | 1 |
| Lorenzini, JL | 1 |
| Mugneret, F | 1 |
| Turc-Carel, C | 1 |
| Bonhomme, J | 1 |
| Guy, H | 1 |
| Raspadori, D | 2 |
| Motta, MR | 1 |
| Tazzari, PL | 2 |
| Biagini, G | 1 |
| Preda, P | 1 |
| Algeri, R | 1 |
| Tura, S | 2 |
| Logan, RA | 1 |
| Smith, NP | 1 |
| Inoue, K | 2 |
| Horikoshi, N | 2 |
| Mukaiyama, T | 2 |
| Itoh, Y | 1 |
| Imajoh, K | 1 |
| Ozeki, H | 2 |
| Nagamine, D | 1 |
| Shinagawa, K | 1 |
| Bird, MC | 1 |
| Bosanquet, AG | 1 |
| Forskitt, S | 1 |
| Gilby, ED | 1 |
| Facskó, A | 1 |
| Németh, J | 1 |
| McNally, PG | 1 |
| Taylor, JM | 1 |
| Wood, JK | 1 |
| Meregalli, M | 1 |
| Nagura, E | 1 |
| Ohno, R | 1 |
| Yamada, K | 1 |
| Akao, Y | 1 |
| Naito, K | 1 |
| Nishikawa, M | 2 |
| Tanaka, H | 2 |
| Shirakawa, S | 1 |
| Ono, Y | 1 |
| Ezaki, K | 1 |
| Streuli, RA | 1 |
| Uemura, Y | 1 |
| Matsuoka, N | 1 |
| Ohno, T | 1 |
| Katayama, N | 1 |
| Tomeoku, M | 1 |
| Kobayashi, T | 1 |
| Kita, K | 1 |
| Minami, N | 1 |
| Keller, JW | 1 |
| Raney, M | 1 |
| Johnson, L | 1 |
| Bartolucci, AA | 1 |
| Omura, GA | 1 |
| Carr, ME | 1 |
| Ito, Y | 1 |
| Nakamura, T | 1 |
| Ueno, K | 1 |
| Imajou, K | 1 |
| Miyaoka, K | 1 |
| Gandara, DR | 1 |
| George, CB | 1 |
| Ries, CA | 1 |
| Koretz, MM | 1 |
| Lewis, JP | 1 |
| Pines, A | 1 |
| Ben-Bassat, I | 1 |
| Modan, M | 1 |
| Blumstein, T | 1 |
| Ramot, B | 2 |
| Adair, CG | 1 |
| Bridges, JM | 1 |
| Desai, ZR | 1 |
| Pegourie, B | 1 |
| Sotto, MF | 1 |
| Martínez-Poventud, G | 1 |
| Fradera, J | 1 |
| Cintrón-López, J | 1 |
| Vélez-García, E | 1 |
| Schmelczer, M | 3 |
| Burger, T | 2 |
| Molnár, L | 2 |
| Schmelzer, M | 1 |
| Montserrat, E | 1 |
| Alcalá, A | 1 |
| Parody, R | 1 |
| Domingo, A | 1 |
| García-Conde, J | 1 |
| Bueno, J | 1 |
| Ferrán, C | 1 |
| Sanz, MA | 1 |
| Rubio, D | 1 |
| Gobbi, M | 1 |
| Cavo, M | 1 |
| Pileri, S | 1 |
| Morozova, EO | 1 |
| Hill, BT | 2 |
| Kay, NE | 1 |
| Douglas, SD | 2 |
| Estren, S | 1 |
| Danieli, G | 1 |
| Obrecht, P | 2 |
| Heilmeyer, L | 1 |
| Hermanský, F | 1 |
| Janele, J | 1 |
| Smetana, K | 1 |
| Hoerni, B | 1 |
| Brunet, R | 1 |
| Hoerni-Simon, G | 1 |
| Patakfalvi, A | 1 |
| Cardamone, JM | 1 |
| Kimmerle, RI | 1 |
| Marshall, EY | 1 |
| Esposito, S | 1 |
| Taylor, LA | 1 |
| Kummer, D | 1 |
| Ochs, HD | 1 |
| Knisley, RE | 1 |
| Settipane, GA | 1 |
| Albala, MM | 1 |
| Dathan, JR | 1 |
| Heyworth, MF | 1 |
| MacIver, AG | 1 |
| Spiers, AS | 1 |
| Sawitsky, B | 1 |
| Lipton, R | 1 |
| Morgenfeld, MC | 2 |
| Helft, F | 2 |
| Bomchil, G | 2 |
| André, R | 1 |
| Duhamel, G | 1 |
| Salmon, C | 1 |
| Najman, A | 1 |
| Homberg, JC | 1 |
| Lebacq, E | 1 |
| Druet, P | 1 |
| Dryll, A | 1 |
| Ryckewaert, A | 1 |
| de Sèze, S | 1 |
| Kahn, MF | 1 |
| Theml, H | 2 |
| Begemann, H | 2 |
| Issels, R | 1 |
| Kaboth, W | 3 |
| Czempiel, H | 1 |
| Winnewisser, M | 1 |
| Najmowicz-Dabrowa, H | 1 |
| Pajak, TF | 1 |
| Rothman, MC | 1 |
| Hervet, E | 1 |
| Barrat, J | 1 |
| Darbois, Y | 1 |
| Faguer, C | 1 |
| Hunold, W | 1 |
| Kuffer, R | 1 |
| Szpirglas, H | 1 |
| Thomas, ED | 1 |
| Neiman, P | 1 |
| Canellos, GP | 1 |
| De Vita, VT | 1 |
| Schein, P | 1 |
| Chabner, B | 1 |
| Young, RC | 1 |
| Cridland, MD | 1 |
| Faĭnshteĭn, FE | 1 |
| Cuni, LJ | 1 |
| Grünwald, H | 1 |
| Rosner, F | 2 |
| Stojcevski, T | 1 |
| Lawler, SD | 2 |
| Lele, KP | 2 |
| Harrap, KR | 1 |
| Shimaoka, K | 1 |
| Desai, DV | 1 |
| Lukásová, M | 1 |
| Pinosová, I | 1 |
| Fitzgerald, PH | 1 |
| Rastrick, JM | 1 |
| Hamer, JW | 1 |
| Ota, H | 1 |
| Morita, A | 1 |
| Yasuma, A | 1 |
| Halkin, H | 1 |
| Meytes, D | 1 |
| Militeanu, J | 1 |
| Themi, H | 1 |
| Auger, C | 1 |
| Morse, BM | 1 |
| Shattil, SJ | 1 |
| Hansen, SH | 1 |
| Vetner, M | 1 |
| DeSimone, PA | 1 |
| Inoue, A | 1 |
| Kinoshita, K | 1 |
| Tomiyasu, T | 1 |
| Tamari, K | 1 |
| Cohen, ML | 1 |
| Weiss, EB | 1 |
| Andreasik, Z | 1 |
| Smolik, R | 1 |
| Trzankowski, J | 1 |
| Rubio, FA | 1 |
| Renner, K | 1 |
| Pentycross, CR | 1 |
| Degos, R | 1 |
| Blanchet, P | 1 |
| Rain, JD | 1 |
| Reboul, D | 1 |
| Israëls, MC | 1 |
| Hardisty, RM | 1 |
| Till, MM | 1 |
| McPhedran, P | 1 |
| Heath, CW | 1 |
| MacKenzie, NG | 1 |
| Chapman, OW | 1 |
| Middleton, PJ | 1 |
| Henefer, EP | 1 |
| Nelson, JF | 1 |
| Beaupre, EM | 1 |
| Shaw, S | 1 |
| White, LP | 1 |
| Stacher, A | 1 |
| Boklan, BF | 1 |
| Benjamin, Z | 1 |
| Smith, E | 1 |
| Gáspár, IA | 1 |
| Petrov, KIa | 1 |
| Rollier, R | 1 |
| Cherkaoui, A | 1 |
| Brittinger, G | 1 |
| König, E | 1 |
| Aberle, HG | 1 |
| Zimmerschitt, E | 1 |
| Kassirskiĭ, IA | 2 |
| Volkova, MA | 2 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase I Trial of Autologous CLL B Cells Transduced to Express Chimeric CD154 (ISF35)[NCT00779883] | Phase 1 | 9 participants (Actual) | Interventional | 2006-06-30 | Completed | ||
| A Phase 1B Extension Trial to Allow Repeat Dosing of Autologous CLL B Cells Transduced to Express Chimeric CD154 (ISF35) in Subjects Previously Treated in MDACC Protocol 2004-0914[NCT00783588] | Phase 1 | 4 participants (Actual) | Interventional | 2007-05-31 | Completed | ||
| Treatment of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL): DNA Microarray Gene Expression Analysis[NCT00001586] | Phase 2 | 105 participants (Actual) | Interventional | 1997-09-30 | Completed | ||
| Phase II Clinical Protocol for the Treatment of Patients With Previously Untreated CLL With Four or Six Cycles of Fludarabine and Cyclophosphamide With Rituximab (FCR) Plus Lenalidomide Followed by Lenalidomide Consolidation/ Maintenance[NCT01723839] | Phase 2 | 21 participants (Actual) | Interventional | 2012-02-22 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Here is the number of participants with adverse events. For the detailed list of adverse events see the adverse event module. (NCT00001586)
Timeframe: 13 years, 10.5 months
| Intervention | Participants (Number) |
|---|---|
| Intermediate-high Risk B-Cell Pts | 18 |
Changes in lymphocyte gene expression was measured by deoxyribonucleic acid (DNA) microarray analysis of circulating leukemic cells after completion of study treatment. A change in expression is defined as a >50% increase in circulating leukemic cells or a 30% decrease in circulating leukemic cells. (NCT00001586)
Timeframe: 6 hours post treatment, and 24 hours post treatment
| Intervention | Percent change in cells (Number) | |
|---|---|---|
| 6 hours post treatment (e.g. ># cells) | 24 hours post treatment (e.g. > # cells) | |
| Intermediate-high Risk B-Cell Pts | 30 | 50 |
Analysis of the Primary Endpoint: The complete responses will be estimated by the number of patients with CR divided by the total number of evaluable patients. (NCT01723839)
Timeframe: 28 day cycle, up to 4 cycles
| Intervention | Percentage of Participants (Number) |
|---|---|
| FCR With Lenalidomide | 45 |
Analysis of the other Secondary Endpoints: The overall response rate will be estimated by the number of patients with complete and partial responses divided by the total number of evaluable patients. (NCT01723839)
Timeframe: 28 day cycle, up to 6 cycles
| Intervention | Percentage of Participants (Number) |
|---|---|
| FCR With Lenalidomide | 95 |
9 reviews available for chlorambucil and Leukemia, Lymphocytic
| Article | Year |
|---|---|
[Therapy of non-Hodgkin's lymphoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cyclophosphamide; Doxorubic | 1984 |
Chronic lymphocytic leukaemia and Hodgkin's disease in the same patient: case report and review of the literature.
Topics: Aged; Bone Marrow; Chlorambucil; Cyclophosphamide; Female; Hodgkin Disease; Humans; Leukemia, Lympho | 1981 |
Treatment of chronic lymphocytic leukaemia.
Topics: Chlorambucil; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Prednisone | 1981 |
[Principles of current chemotherapy of lymphocytic leukemia (review of the literature)].
Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Aziridines; Chlorambucil; Cyc | 1979 |
Chemotherapy in chronic lymphocytic leukaemia.
Topics: Adrenal Cortex Hormones; Bacterial Infections; Bone Marrow; Cell Transformation, Neoplastic; Chloram | 1977 |
Treatment of chronic lymphocytic leukemia.
Topics: Adrenal Cortex Hormones; Alkylating Agents; Chlorambucil; Cyclophosphamide; Drug Therapy, Combinatio | 1977 |
Chlorambucil induced pulmonary fibrosis: report of a case and review.
Topics: Chlorambucil; Humans; Leukemia, Lymphoid; Lung; Male; Middle Aged; Pulmonary Fibrosis | 1986 |
[Clinical aspects of the problem of treating leukemias].
Topics: Acute Disease; Antineoplastic Agents; Chlorambucil; Chlorine; Chronic Disease; Daunorubicin; Dimetho | 1973 |
[Therapy of chronic leukemia].
Topics: Antineoplastic Agents; Busulfan; Chlorambucil; Female; Glucocorticoids; Humans; Leukemia; Leukemia, | 1968 |
13 trials available for chlorambucil and Leukemia, Lymphocytic
| Article | Year |
|---|---|
Treatment of chronic lymphocytic leukaemia and well-differentiated lymphocytic lymphoma with continuous low- or intermittent high-dose prednimustine versus chlorambucil/prednisolone.
Topics: Adult; Aged; Chlorambucil; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; | 1982 |
Clinical trial of prednimustine, Leo-1031 (NSC-134087), in patients with non-Hodgkin lymphomata and chronic lymphocytic leukaemia previously treated with steroids and alkylating agents.
Topics: Adult; Aged; Chlorambucil; Clinical Trials as Topic; Female; Humans; Leukemia, Lymphoid; Lymphoma; M | 1980 |
The comparison of total body irradiation vs chlorambucil and prednisone for remission induction of active chronic lymphocytic leukemia: an ECOG study. Part I: total body irradiation-response and toxicity.
Topics: Agranulocytosis; Chlorambucil; Clinical Trials as Topic; Hematopoietic Stem Cells; Humans; Leukemia, | 1981 |
[Effect of Prednimustine (Leo 1031) in chronic lymphatic leukemia].
Topics: Adult; Aged; Chlorambucil; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Female; Gin | 1977 |
A phase II clinical trial of prednimustine. Clinical screening cooperative group of E.O.R.T.C.
Topics: Adolescent; Adult; Aged; Chlorambucil; Clinical Trials as Topic; Female; Humans; Leukemia, Lymphoid; | 1977 |
Comparison of daily versus intermittent chlorambucil and prednisone therapy in the treatment of patients with chronic lymphocytic leukemia.
Topics: Anemia; Chlorambucil; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administratio | 1977 |
Comparison of daily versus intermittent chlorambucil and prednisone therapy in the treatment of patients with chronic lymphocytic leukemia.
Topics: Anemia; Chlorambucil; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administratio | 1977 |
Comparison of daily versus intermittent chlorambucil and prednisone therapy in the treatment of patients with chronic lymphocytic leukemia.
Topics: Anemia; Chlorambucil; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administratio | 1977 |
Comparison of daily versus intermittent chlorambucil and prednisone therapy in the treatment of patients with chronic lymphocytic leukemia.
Topics: Anemia; Chlorambucil; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administratio | 1977 |
Treatment of chronic lymphocytic leukemia and lymphosarcoma with a new chlorambucil ester of prednisolone (Leo 1031) (NSC-134087).
Topics: Chlorambucil; Clinical Trials as Topic; Female; Humans; Leukemia, Lymphoid; Lymphoma, Non-Hodgkin; P | 1975 |
Effectiveness of "CHOP" regimen in advanced untreated chronic lymphocytic leukaemia. French Cooperative Group on Chronic Lymphocytic Leukaemia.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Clinical Trials as Topic; Cyclop | 1986 |
Prognostic and therapeutic advances in CLL management: the experience of the French Cooperative Group. French Cooperative Group on Chronic Lymphocytic Leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Clinical Trials as Topic; Cyclophospha | 1987 |
[Clinical trial of bestrabucil (KM 2210) on hematopoietic malignancies].
Topics: Aged; Chlorambucil; Clinical Trials as Topic; Drug Administration Schedule; Estradiol; Female; Human | 1986 |
Treatment of chronic lymphocytic leukemia using chlorambucil and prednisone with or without cycle-active consolidation chemotherapy. A Southeastern Cancer Study Group Trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Clinical Trials as Topic; Cyclophospha | 1986 |
Treatment of chronic lymphocytic leukemia in advanced stages. A randomized trial comparing chlorambucil plus prednisone versus cyclophosphamide, vincristine, and prednisone.
Topics: Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Clinical Trials as Topic | 1985 |
Chlorambucil vs. combined chlorambucil-corticosteroid therapy in chronic lymphocytic leukemia.
Topics: Adult; Aged; Blood Cell Count; Bone Marrow; Bone Marrow Cells; Chlorambucil; Drug Synergism; Female; | 1973 |
Chlorambucil vs. combined chlorambucil-corticosteroid therapy in chronic lymphocytic leukemia.
Topics: Adult; Aged; Blood Cell Count; Bone Marrow; Bone Marrow Cells; Chlorambucil; Drug Synergism; Female; | 1973 |
Chlorambucil vs. combined chlorambucil-corticosteroid therapy in chronic lymphocytic leukemia.
Topics: Adult; Aged; Blood Cell Count; Bone Marrow; Bone Marrow Cells; Chlorambucil; Drug Synergism; Female; | 1973 |
Chlorambucil vs. combined chlorambucil-corticosteroid therapy in chronic lymphocytic leukemia.
Topics: Adult; Aged; Blood Cell Count; Bone Marrow; Bone Marrow Cells; Chlorambucil; Drug Synergism; Female; | 1973 |
233 other studies available for chlorambucil and Leukemia, Lymphocytic
| Article | Year |
|---|---|
Diagnosis and treatment of chronic lymphocytic leukemia in a bat-eared fox (Otocyon megalotis).
Topics: Animals; Animals, Zoo; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Chlorambu | 2014 |
Clinical experience with CB 1348 (NN-di(2-chloroethyl, -P-aminophenylbutyric acid) in the treatment of chronic lymphatic leukaemia.
Topics: Chlorambucil; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Mechlorethamine; | 1957 |
[Severe terminal purpura during CB 1348 therapy of chronic lymphoid leukemia].
Topics: Chlorambucil; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Mechlorethamine; | 1957 |
[Lymphoid leukemia treated by the combination of cortisone, CB 1348 & transfusions].
Topics: Blood Transfusion; Chlorambucil; Cortisone; Leukemia; Leukemia, Lymphoid; Mechlorethamine; Nitrogen | 1958 |
[Observations on the application of CB-1348 in lymphatic leukemias].
Topics: Chlorambucil; Humans; Leukemia; Leukemia, Lymphoid; Mechlorethamine; Nitrogen Mustard Compounds | 1959 |
The use of chlorambucil and steroids in the treatment of chronic lymphocytic leukaemia.
Topics: Adrenal Cortex Hormones; Chlorambucil; Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leu | 1961 |
Evaluation of the effectiveness of radioactive phosphorus and chlorambucil in patients with chronic lymphocytic leukemia.
Topics: Chlorambucil; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Lymphocytes; Mec | 1962 |
TREATMENT OF CHRONIC LEUKEMIC LYMPHOCYTIC LEUKEMIA WITH TRIETHYLENE MELAMINE (TEM) AND CHLORAMBUCIL (CB-1348).
Topics: Chlorambucil; Leukemia; Leukemia, Lymphoid; Lymphocytes; Triethylenemelamine | 1963 |
LEUKEMIA. AN ANALYSIS OF 209 CASES FROM THE ELLIS FISCHEL STATE CANCER HOSPITAL.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antineoplastic Agents; Busulfan; Cancer Care Facilit | 1963 |
DRUGS IN THE TREATMENT OF LEUKAEMIA.
Topics: Busulfan; Chlorambucil; Cyclophosphamide; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; M | 1963 |
CUTANEOUS GRANULOMA WITH EOSINOPHILS.
Topics: Chlorambucil; Classification; Dermatology; Diagnosis, Differential; Eosinophilic Granuloma; Eosinoph | 1963 |
CHRONIC LYMPHATIC LEUKAEMIA AND ITS MANAGEMENT.
Topics: Adrenal Cortex Hormones; Chlorambucil; Geriatrics; Humans; Leukemia; Leukemia, Lymphoid; Mechloretha | 1963 |
CLINICAL EVALUATION OF URACIL MUSTARD.
Topics: Anemia; Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Female; Hodgkin Disease; Humans; Kidn | 1963 |
[HOW TO TREAT LEUKEMIA IN 1963].
Topics: Busulfan; Child; Chlorambucil; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopuri | 1963 |
THE RETICULOSES.
Topics: Adrenal Cortex Hormones; Chlorambucil; Cyclophosphamide; Dermatitis, Exfoliative; Genetic Diseases, | 1964 |
MULTIVARIATE COMPARISON OF RESULTS OF TREATMENT IN CHRONIC LYMPHOCYTIC AND CHRONIC GRANULOCYTIC LEUKEMIA.
Topics: Antineoplastic Agents; Blood Platelets; Busulfan; Chlorambucil; Factor Analysis, Statistical; Hemogl | 1964 |
WEEKLY HIGH-DOSAGE GLUCOCORTICOSTEROID TREATMENT OF LYMPHOCYTIC LEUKEMIAS AND LYMPHOMAS.
Topics: Anemia; Anemia, Hemolytic; Betamethasone; Chlorambucil; Dexamethasone; Geriatrics; Humans; Leukemia; | 1964 |
[EXPERIENCE IN THE TREATMENT OF MALIGNANT DISEASES OF THE RETICULOENDOTHELIAL SYSTEM AND LEUKEMIAS. II].
Topics: Betamethasone; Busulfan; Chlorambucil; Copper; Cyclophosphamide; Dexamethasone; Genetic Diseases, X- | 1964 |
IN-VITRO SENSITIVITY TESTS OF LEUKAEMIC CELLS TO CHEMOTHERAPEUTIC AGENTS.
Topics: Aminopterin; Animals; Antineoplastic Agents; Busulfan; Chlorambucil; Cyclophosphamide; Geriatrics; H | 1964 |
CHRONIC LEUKEMIA.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Alkylating Agents; Anemia; Anemia, Hemolytic, | 1964 |
PLASMA FACTORS IN LEUKAEMIA. IMMUNOLOGICAL AND "IN VITRO" CULTURAL STUDIES.
Topics: Blood Group Antigens; Busulfan; Chlorambucil; Complement Fixation Tests; Coombs Test; Humans; In Vit | 1964 |
CHEMOTHERAPY OF CHRONIC LYMPHOCYTIC LEUKEMIA.
Topics: Blood Platelets; Chlorambucil; Cyclophosphamide; Drug Therapy; Hematocrit; Hemoglobinometry; Humans; | 1964 |
ANTI-LEUKAEMIC DRUGS.
Topics: Busulfan; Chlorambucil; Cyclophosphamide; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; M | 1964 |
TREATMENT OF CHRONIC LYMPHOCYTIC LEUKEMIA WITH CHLORAMBUCIL (NSC-3088) AND CYCLOPHOSPHAMIDE (NSC-26271).
Topics: Chlorambucil; Cyclophosphamide; Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, | 1964 |
MEDICAL GRAND ROUNDS FROM THE UNIVERSITY OF ALABAMA MEDICAL CENTER.
Topics: Beta-Globulins; Blood Protein Disorders; Bone Marrow Examination; Bone Resorption; Chlorambucil; Dia | 1964 |
CHLORAMBUCIL THERAPY FOR LYMPHOMAS AND CHRONIC LYMPHOCYTIC LEUKEMIA.
Topics: Adrenal Cortex Hormones; Chlorambucil; Drug Synergism; Hodgkin Disease; Leukemia; Leukemia, Lymphocy | 1965 |
THE ROLE OF THE PHAGOCYTE IN HOST-PARASITE INTERACTIONS. I. THE PHAGOCYTIC CAPABILITIES OF LEUKOCYTES FROM LYMPHOPROLIFERATIVE DISORDERS.
Topics: Chlorambucil; Drug Therapy; Escherichia coli Infections; Geriatrics; Host-Parasite Interactions; Hum | 1964 |
EXPECTANCY FOR LIFE IN CHRONIC LYMPHATIC LEUKEMIA.
Topics: Adrenal Cortex Hormones; Alkylating Agents; Antineoplastic Agents; Child; Chlorambucil; Cyclophospha | 1965 |
[TREATMENT OF CHRONIC LYMPHADENOSIS].
Topics: Adrenal Cortex Hormones; Chlorambucil; Drug Therapy; Humans; Leukemia; Leukemia, Lymphoid; Triethyle | 1965 |
[MODERN TREATMENT OF LEUKEMIA].
Topics: Agranulocytosis; Busulfan; Chlorambucil; Cyclophosphamide; Drug Therapy; Genetic Diseases, X-Linked; | 1965 |
ALTERATION OF BLOOD GROUP ANTIGENS IN LEUKEMIC LYMPHOCYTES.
Topics: ABO Blood-Group System; Anemia; Anemia, Aplastic; Antigens; Blood Group Antigens; Child; Chlorambuci | 1965 |
[FINDINGS ON A CASE OF CHRONIC LYMPHATIC LEUKOSIS WITH ASCITES AND ITS THERAPY].
Topics: Ascites; Chlorambucil; Humans; Leukemia; Leukemia, Lymphoid | 1965 |
Treatment of malignant lymphomas and lymphadenoses with leukeran.
Topics: Chlorambucil; Hodgkin Disease; Leukemia; Leukemia, Lymphoid; Lymphoma; Mechlorethamine; Nitrogen Mus | 1959 |
Clinical and haematological observations in lymphoma patients (Hodgkin's disease, Brill-Symmer's disease, lymphogenous leukaemia) treated with N N Di-2-chloroethyl gamma-P-aminophenyl butiric acid (amboclorin).
Topics: Antineoplastic Agents; Chlorambucil; Hodgkin Disease; Humans; Leukemia, Lymphoid; Lymphoma; Lymphoma | 1960 |
Comparison of CB-1348 (chlorambucil, leukeran) and CB-1364.
Topics: Antineoplastic Agents; Chlorambucil; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Mechlo | 1962 |
High dose chlorambucil in the treatment of lymphoid malignancies.
Topics: Antineoplastic Agents, Alkylating; Chlorambucil; Clinical Trials as Topic; Hodgkin Disease; Humans; | 2004 |
Pharmacokinetic and cell-biological investigation of prednimustine compared to its components chlorambucil and prednisolone.
Topics: Animals; Breast Neoplasms; Cell Division; Cell Line; Cell Line, Tumor; Chlorambucil; Cricetinae; Fem | 1989 |
[Lymphoid leukemias of prolonged evolution. Apropos of 8 observations].
Topics: Adult; Aged; Chlorambucil; Female; Humans; Leukemia, Lymphoid; Male; Middle Aged | 1966 |
Unstable rapidly labelled RNA in chronic lymphocytic leukaemic cells.
Topics: Autoradiography; Cell Division; Chlorambucil; Culture Techniques; Dactinomycin; Humans; Lectins; Leu | 1967 |
Action of elatericin A on human leukemic and normal lymphocytes.
Topics: Aminopterin; Animals; Antineoplastic Agents; Azirines; Cathartics; Cell Nucleus; Chlorambucil; Cyclo | 1967 |
Complete remission in chronic lymphocytic leukemia and leukolymphosarcoma.
Topics: Aged; Chlorambucil; Female; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma, Non-Hodgkin; Male; Middl | 1967 |
Nucleoli of peripheral blood lymphocytes in patients with chronic lymphocytic leukemia.
Topics: Adult; Aged; Antineoplastic Agents; Cell Nucleolus; Chlorambucil; Humans; Leukemia, Lymphoid; Leukoc | 1980 |
[Experiences in the treatment of non-Hodgkin lymphomas].
Topics: Antineoplastic Agents; Chlorambucil; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Lymphoma | 1981 |
Chronic lymphocytic leukemia.
Topics: Chlorambucil; Cyclophosphamide; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Neoplasm Stag | 1982 |
Chronic lymphocytic leukemia in the elderly.
Topics: Aged; B-Lymphocytes; Chlorambucil; Diagnosis, Differential; Glucosephosphate Dehydrogenase; Humans; | 1982 |
[Acute myeloid leukemia secondary to chronic lymphoid leukemia].
Topics: Chlorambucil; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Time Factors | 1984 |
Phase II trial of prednimustine in children with recurrent cancer: a Children's Cancer Study Group report.
Topics: Adolescent; Adult; Carcinoma, Hepatocellular; Child; Child, Preschool; Chlorambucil; Drug Administra | 1982 |
Effect of food on pharmacokinetics of chlorambucil and its main metabolite, phenylacetic acid mustard.
Topics: Adult; Aged; Biotransformation; Chlorambucil; Eating; Female; Humans; Kinetics; Leukemia, Lymphoid; | 1984 |
Chronic lymphocytic leukaemia (CLL): clinical study at Kenyatta National Hospital (KNH).
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Female; Human | 1984 |
[Testicular damage caused by chemotherapy in acute lymphoblastic leukemia].
Topics: Adolescent; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; C | 1983 |
Acute lymphoblastic leukemia supervening in a case of chronic lymphocytic leukemia after continuous 3-year treatment with chlorambucil.
Topics: Aged; Bone Marrow; Chlorambucil; Humans; Karyotyping; Leukemia, Lymphoid; Male | 1984 |
Coexistence of chronic myelogenous leukemia and chronic lymphocytic leukemia.
Topics: Aged; Chlorambucil; Chromosomes, Human, 21-22 and Y; Female; Humans; Leukemia, Lymphoid; Leukemia, M | 1984 |
The dynamics of morphological and cytoenzymatic changes in peripheral blood lymphocyte lysosomes in patients with chronic lymphocytic leukemia during treatment.
Topics: Acid Phosphatase; Adult; Aged; Chlorambucil; Cyclophosphamide; Drug Therapy, Combination; Histocytoc | 1983 |
Nucleoli in peripheral blood lymphocytes of patients with chronic lymphocytic leukemia treated with cytostatic drugs.
Topics: Cell Nucleolus; Chlorambucil; Cyclophosphamide; Drug Therapy, Combination; Humans; Leukemia, Lymphoi | 1983 |
[Results of cytostatic polychemotherapy in non-Hodgkin lymphomas].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Doxorubicin; Drug Th | 1983 |
[KM 2210 therapy for chronic lymphocytic leukemia].
Topics: Aged; Chlorambucil; Estradiol; Humans; Leukemia, Lymphoid; Male | 1983 |
[Alveolitis and lung fibrosis following therapy with chlorambucil].
Topics: Chlorambucil; Female; Humans; Leukemia, Lymphoid; Lung; Middle Aged; Pneumonia; Pulmonary Alveoli; P | 1984 |
[Chronic myelocytic leukemia. Therapy in lymphadenosis (CLL)].
Topics: Blood Viscosity; Cell Division; Chlorambucil; Cyclophosphamide; Female; Humans; Immunoglobulins; Leu | 1980 |
Response to therapy as prognostic factor in chronic lymphocytic leukemia.
Topics: Chlorambucil; Drug Therapy, Combination; Female; Humans; Leukemia, Lymphoid; Male; Neoplasm Staging; | 1980 |
[Hairy cell leukemia].
Topics: Chlorambucil; Diagnosis, Differential; Heavy Chain Disease; Humans; Leukemia, Hairy Cell; Leukemia, | 1982 |
Free light chains of immunoglobulins in serum from patients with leukaemias and multiple myeloma.
Topics: Adolescent; Adult; Aged; Child; Chlorambucil; Humans; Immunoglobulin kappa-Chains; Immunoglobulin la | 1982 |
Familial leukemia: uncommon type of chronic lymphocytic leukemia in two sisters.
Topics: Agammaglobulinemia; Anemia; Chlorambucil; Female; Humans; Leukemia, Lymphoid; Middle Aged; Prednison | 1982 |
Common hematologic problems: diagnosis and treatment.
Topics: Aged; Anemia; Anemia, Macrocytic; Blood Cell Count; Blood Transfusion; Chlorambucil; Erythrocyte Ind | 1983 |
Murine monoclonal antibody therapy in two patients with chronic lymphocytic leukemia.
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chlor | 1982 |
Acute leukemia after cytotoxic treatment for nonmalignant disease in childhood. A case report and review of the literature.
Topics: Antineoplastic Agents; Child; Chlorambucil; Cyclophosphamide; Cytarabine; Humans; Leukemia, Lymphoid | 1981 |
Chronic lymphatic leukaemia terminating as erythroleukaemia.
Topics: Aged; Chlorambucil; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Male; Time Factors | 1981 |
Myeloproliferative disease developing in chronic lymphocytic leukaemia.
Topics: Aged; Chlorambucil; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Male | 1982 |
Treatment of prolymphocytic leukemia.
Topics: Aged; Chlorambucil; Female; Humans; Leukemia, Lymphoid; Leukocyte Count; Male; Middle Aged; Platelet | 1982 |
[Present status of chemotherapy in ALL and CLL].
Topics: Adult; Antineoplastic Agents; Child; Chlorambucil; Daunorubicin; Doxorubicin; Drug Therapy, Combinat | 1982 |
[Prolymphocytic leukemia: clinical, cytologic and immunologic findings].
Topics: Aged; B-Lymphocytes; Cell Differentiation; Chlorambucil; Female; Humans; Leukemia, Lymphoid; Lymphoc | 1980 |
Reduced T-colony forming capacity in B-chronic lymphocytic leukaemia.--II. Correlation with clinical stage and findings in B-prolymphocytic leukaemia.
Topics: B-Lymphocytes; Cell Division; Chlorambucil; Humans; Immunoglobulin M; Leukemia, Lymphoid; Neoplasm S | 1982 |
[Recovery from from Listeria monocytogenes meningitis in an adult].
Topics: Aged; Cefuroxime; Chlorambucil; Humans; Immunosuppressive Agents; Leukemia, Lymphoid; Male; Meningit | 1982 |
Acute obstructive uric acid nephropathy after treatment of neoplastic adenopathy.
Topics: Acute Disease; Chlorambucil; Constriction, Pathologic; Female; Humans; Kidney Diseases; Leukemia, Ly | 1981 |
[Prognosis in chronic lymphocytic leukemia].
Topics: Agammaglobulinemia; Chlorambucil; Hematopoietic Stem Cells; Humans; Leukemia, Lymphoid; Leukocyte Co | 1981 |
Total tumour mass score (TTM): a new parameter in chronic lymphocyte leukaemia.
Topics: Bone Marrow; Chlorambucil; Female; Humans; Leukemia, Lymphoid; Leukocyte Count; Lymph Nodes; Male; M | 1981 |
[Irradiation of the thymus region in chronic lymphoid leukaemia. Seven cases (author's transl)].
Topics: Aged; Chlorambucil; Female; Follow-Up Studies; Humans; Leukemia, Lymphoid; Male; Mediastinum; Middle | 1981 |
Specific immunoadsorption of IgG antibody in a patient with chronic lymphocytic leukemia and autoimmune hemolytic anemia. A new form of therapy for the acute critical stage.
Topics: Adsorption; Aged; Anemia, Hemolytic, Autoimmune; Antibody Specificity; Cell Separation; Chlorambucil | 1981 |
3H-thymidine uptake in chronic lymphocytic leukaemia cells.
Topics: Absorption; Chlorambucil; Humans; Leukemia, Lymphoid; Leukocyte Count; Lymphocytes; Prednisolone; Pr | 1980 |
Management of CLL patients after chlorambucil therapy. Special value of a second RAI staging.
Topics: Aged; Chlorambucil; Female; Humans; Leukemia, Lymphoid; Male; Neoplasm Staging; Prognosis; Splenecto | 1980 |
Primary malignant neoplasms associated with chronic lymphocytic leukemia.
Topics: Breast Neoplasms; Chlorambucil; Colonic Neoplasms; Cyclophosphamide; Female; Head and Neck Neoplasms | 1980 |
[Prolymphocytic leukemia of long evolution].
Topics: Aged; Chlorambucil; Humans; Leukemia, Lymphoid; Male | 1980 |
Biweekly chlorambucil treatment of lymphocytic lymphoma.
Topics: Antineoplastic Agents; Chlorambucil; Drug Evaluation; Drug Therapy, Combination; Follow-Up Studies; | 1980 |
Fatal interstitial pneumonitis following high-dose intermittent chlorambucil therapy for chronic lymphocyte leukemia.
Topics: Aged; Alveolitis, Extrinsic Allergic; Biopsy; Chlorambucil; Dose-Response Relationship, Drug; Humans | 1981 |
Association of B-chronic lymphocytic leukaemia and T-large granular lymphocyte leukaemia.
Topics: Aged; Aged, 80 and over; CD56 Antigen; Chlorambucil; Cytogenetics; Fatal Outcome; Gene Rearrangement | 2000 |
Fulminant hepatic failure in leukaemia and choriocarcinoma related to withdrawal of cytotoxic drug therapy.
Topics: Adult; Antineoplastic Agents; Chlorambucil; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Female; | 1975 |
Studies on the lymphozyte subpopulations in chronic lymphocytic leukaemia.
Topics: B-Lymphocytes; Chlorambucil; Cyclophosphamide; Humans; Leukemia, Lymphoid; Prednisone; T-Lymphocytes | 1976 |
Focal fits during chlorambucil therapy.
Topics: Age Factors; Chlorambucil; Epilepsies, Partial; Humans; Leukemia, Lymphoid; Male; Middle Aged | 1979 |
Effect of treatment on T-cell function in chronic lymphocytic leukaemia.
Topics: Chlorambucil; Humans; Leukemia, Lymphoid; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Pre | 1978 |
Chronic lymphatic leukaemia, chlorambucil, and sensorimotor peripheral neuropathy.
Topics: Chlorambucil; Humans; Leukemia, Lymphoid; Male; Middle Aged; Peripheral Nervous System Diseases; Pre | 1977 |
Cancer chemotherapy.
Topics: Chlorambucil; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Female; Hodgkin Disease; Humans; Leuk | 1977 |
Diagnosis and treatment of canine hematopoietic neoplasms.
Topics: Animals; Chlorambucil; Dog Diseases; Dogs; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma | 1977 |
Inadvertent chlorambucil overdose in adult.
Topics: Chlorambucil; Humans; Leukemia, Lymphoid; Male; Medication Errors; Middle Aged; Remission, Spontaneo | 1977 |
[When do we have to treat chronic leukemia?].
Topics: Busulfan; Chlorambucil; Chromosome Aberrations; Cyclophosphamide; Drug Therapy, Combination; Female; | 1978 |
[Evolutionary aspects of the picture of pulmonary pathology in the course of chronic blood diseases (a correlation with cytostatic treatment)].
Topics: Adult; Aged; Antineoplastic Agents; Busulfan; Chlorambucil; Female; Humans; Leukemia, Lymphoid; Leuk | 1979 |
Managing chronic leukemias.
Topics: Adult; B-Lymphocytes; Chlorambucil; Female; Granulocytes; Humans; Leukemia, Lymphoid; Leukemia, Myel | 1977 |
[Prolymphocytic leukaemia (author's transl)].
Topics: Aged; B-Lymphocytes; Chlorambucil; Daunorubicin; Female; Humans; Leukemia, Lymphoid; Methylprednisol | 1979 |
[Correlations between lymphocyte subpopulation and stage of disease in chronic lymphatic leukemia of Rai].
Topics: Aged; B-Lymphocytes; Cell Separation; Chlorambucil; Humans; Leukemia, Lymphoid; Middle Aged; Neoplas | 1977 |
Hyperviscosity syndrome associated with lymphocytic leukemia in three dogs.
Topics: Animals; Blood Viscosity; Chlorambucil; Dog Diseases; Dogs; Immunoglobulin A; Immunoglobulin M; Leuk | 1977 |
Macroglobulinemia of Waldenström associated with severe osteolytic lesions.
Topics: Aged; Bone Resorption; Chlorambucil; Female; Humans; Leukemia, Lymphoid; Osteolysis; Waldenstrom Mac | 1977 |
Intermittent combination chemotherapy with chlorambucil and prednisone of low-grade malignant non-Hodgkin's lymphomas according to the Kiel classification.
Topics: Adult; Aged; Bone Marrow; Chlorambucil; Drug Administration Schedule; Drug Therapy, Combination; Fem | 1979 |
Interstitial pneumonia and chlorambucil.
Topics: Aged; Chlorambucil; Humans; Leukemia, Lymphoid; Male; Pulmonary Fibrosis | 1979 |
Pharmacokinetics and metabolism of chlorambucil in patients with malignant disease.
Topics: Administration, Oral; Chlorambucil; Female; Humans; Injections, Intravenous; Kinetics; Leukemia, Lym | 1979 |
Pharmacokinetics and metabolism of chlorambucil in man: a preliminary report.
Topics: Administration, Oral; Adult; Aged; Chlorambucil; Female; Humans; Intestinal Absorption; Leukemia, Ly | 1979 |
[Studies on cell-mediated immunity in patients with chronic lymphatic leukemia].
Topics: Aged; Chlorambucil; Cyclophosphamide; Female; Humans; Immunity, Cellular; Lectins; Leukemia, Lymphoi | 1977 |
When autoimmune hemolytic anemia complicates chronic lymphocytic leukemia.
Topics: Aged; Anemia, Hemolytic, Autoimmune; Azathioprine; Chlorambucil; Female; Humans; Leukemia, Lymphoid; | 1978 |
The control of chronic lymphocytic leukemia with mediastinal irradiation.
Topics: Chlorambucil; Humans; Immunoglobulin G; Immunoglobulin M; Leukemia, Lymphoid; Leukocyte Count; Lymph | 1978 |
[Familial occurrence of chronic lymphatic leukemia. HL-A antigen and cytogenetic studies].
Topics: Aged; Chlorambucil; Chromosome Aberrations; Chromosomes, Human, 21-22 and Y; HLA Antigens; Humans; L | 1978 |
Chronic lymphocytic leukemia.
Topics: Aged; Chlorambucil; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Leukemia, Lymphoid; | 1978 |
In vivo and in vitro selection of mitogen responsive lymphocytes in patients with chronic lymphocytic leukemia.
Topics: Adult; Aged; Cell Separation; Chlorambucil; Concanavalin A; Cyclophosphamide; Female; Humans; Immuno | 1976 |
A clinical staging system for chronic lymphocytic leukemia: prognostic significance.
Topics: Bone Marrow; Chlorambucil; Female; Humans; Leukemia, Lymphoid; Leukocyte Count; Lymph Nodes; Lymphoc | 1977 |
[Proliferation and growth of lymphatic cell population in malignant lymphomas].
Topics: Chlorambucil; Cytogenetics; Hematopoiesis; Hodgkin Disease; Humans; Leukemia, Lymphoid; Lymphocytes; | 1976 |
Immunosuppressive drug therapy as a potentiator of skin tumours in five patients with lymphoma.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Chlorambucil; H | 1976 |
The role of drug transport in resistance to nitrogen mustard and other alkylating agents in L518Y lymphoblsts.
Topics: Alkylating Agents; Animals; Binding, Competitive; Biological Transport; Carmustine; Cell Line; Chlor | 1975 |
Diagnostic and therapeutic approach to chronic leukaemia.
Topics: Busulfan; Chlorambucil; Chronic Disease; Diagnosis, Differential; Glucocorticoids; Leukemia; Leukemi | 1975 |
Evaluation of the hypothalamic-pituitary-adrenocortical axis in chronic leukaemia.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Adult; Aged; Busulfan; Chloramb | 1976 |
Influence of prednisone and cytostatics on human blood B-, T- and O-lymphocytes in diseases.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Azathioprine; B-Lymphocytes; Child; Chlorambucil; Co | 1975 |
Adenosine deaminase activity in chronic lymphocytic leukemia. Relationship to B- and T-cell subpopulations.
Topics: Adenosine Deaminase; B-Lymphocytes; Chlorambucil; Humans; Isoenzymes; Leukemia, Lymphoid; Leukocyte | 1976 |
Chronic lymphocytic leukemia: studies on the effect of drug treatment on different lymphocytic subpopulations.
Topics: Adult; Antineoplastic Agents; B-Lymphocytes; Chlorambucil; Cyclophosphamide; Humans; Immunoglobulin | 1976 |
Busulphan toxicity syndrome caused by chlorambucil.
Topics: Aged; Busulfan; Chlorambucil; Female; Humans; Leukemia, Lymphoid; Male; Middle Aged; Pigmentation Di | 1975 |
Therapeutic effect of Leo 1031, an alkylating corticosteroid ester, in lymphoproliferative disorders. I. chronic lymphocytic leukaemia.
Topics: Adult; Aged; Chlorambucil; Drug Evaluation; Esters; Female; Humans; Leukemia, Lymphoid; Male; Middle | 1975 |
Clinical staging of chronic lymphocytic leukemia.
Topics: Adrenal Cortex Hormones; Age Factors; Aged; Anemia; Blood Cell Count; Bone Marrow Examination; Chlor | 1975 |
Clinical staging of chronic lymphocytic leukemia.
Topics: Adrenal Cortex Hormones; Age Factors; Aged; Anemia; Blood Cell Count; Bone Marrow Examination; Chlor | 1975 |
Clinical staging of chronic lymphocytic leukemia.
Topics: Adrenal Cortex Hormones; Age Factors; Aged; Anemia; Blood Cell Count; Bone Marrow Examination; Chlor | 1975 |
Clinical staging of chronic lymphocytic leukemia.
Topics: Adrenal Cortex Hormones; Age Factors; Aged; Anemia; Blood Cell Count; Bone Marrow Examination; Chlor | 1975 |
[Specific leukemic infiltration with the appearance of erythema annulare centrifugum (Darier) in chronic lymphadenosis].
Topics: Chlorambucil; Erythema; Humans; Leukemia, Lymphoid; Lip; Male; Middle Aged | 1975 |
Progression of a human B cell chronic lymphocytic leukemia line in nude mice.
Topics: Animals; B-Lymphocytes; Cell Division; Cell Transformation, Viral; Chlorambucil; Chronic Disease; Fr | 1988 |
[Acute myeloid leukemia in chronic lymphoid leukemia treated with chlorambucil].
Topics: Chlorambucil; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged | 1986 |
T-cell prolymphocytic leukaemia: a clinical and immunological study.
Topics: Acid Phosphatase; Aged; Antibodies, Monoclonal; B-Lymphocytes; Chlorambucil; Cyclophosphamide; Femal | 1985 |
Cutaneous presentation of prolymphocytic leukaemia.
Topics: Chlorambucil; Coformycin; Humans; Leukemia, Lymphoid; Leukocyte Count; Male; Middle Aged; Pentostati | 1988 |
[Phase II study of chlorambucil in patients with hematological malignancies].
Topics: Administration, Oral; Adult; Aged; Chlorambucil; Drug Administration Schedule; Drug Evaluation; Fema | 1987 |
Long-term comparison of results of a drug sensitivity assay in vitro with patient response in lymphatic neoplasms.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Drug Screening | 1988 |
[Unilateral infiltration of the optic papilla in chronic lymphatic leukemia].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Eye Neoplasms; Female; Fluoresce | 1988 |
Progressive multifocal leucoencephalopathy associated with chronic lymphocytic leukaemia.
Topics: Biopsy; Bone Marrow; Brain; Chlorambucil; Chronic Disease; Humans; Leukemia, Lymphoid; Leukoencephal | 1988 |
[A case of chronic lymphatic leukemia associated with polycythemia vera].
Topics: Aged; Chlorambucil; Humans; Leukemia, Lymphoid; Male; Polycythemia Vera; Prednisone | 1987 |
[Early phase II trial of bestrabucil in hematological malignancies].
Topics: Adult; Aged; Chlorambucil; Drug Administration Schedule; Drug Evaluation; Estradiol; Female; Humans; | 1986 |
[Chronic lymphatic leukemia].
Topics: Bone Marrow; Chlorambucil; Humans; Leukemia, Lymphoid; Leukocyte Count; Lymphocytosis; Lymphoma; Mal | 1986 |
[Phase II study of prednimustine in follicular lymphoma and chronic lymphocytic leukemia].
Topics: Administration, Oral; Adult; Aged; Chlorambucil; Drug Administration Schedule; Drug Evaluation; Fema | 1987 |
Treatment of refractory chronic lymphocytic leukemia with prednimustine: a phase II study using strict response criteria.
Topics: Alkylating Agents; Chlorambucil; Humans; Leukemia, Lymphoid; Middle Aged; Prednimustine | 1987 |
Survival and prognostic factors in chronic lymphocytic leukemia.
Topics: Adult; Chlorambucil; Data Collection; Female; Follow-Up Studies; Humans; Leukemia, Lymphoid; Male; M | 1987 |
Can food affect the bioavailability of chlorambucil in patients with haematological malignancies?
Topics: Adult; Aged; Biological Availability; Chlorambucil; Chromatography, High Pressure Liquid; Fasting; F | 1986 |
Splenectomy during chronic lymphocytic leukemia.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combin | 1987 |
Chronic lymphocytic leukemia: a study of 53 patients and review of the literature.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined Mod | 1985 |
[Serum beta 2 microglobulin in chronic lymphoid leukemia].
Topics: Aged; beta 2-Microglobulin; Chlorambucil; Female; Humans; Leukemia, Lymphoid; Leukocyte Count; Male; | 1985 |
Serum beta-2 microglobulin in chronic lymphocytic leukaemia.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; beta 2-Microglobulin; Chlorambucil; Female; Hu | 1985 |
Meningeal leukemia complicating prolymphocytoid transformation of B-chronic lymphocytic leukemia.
Topics: B-Lymphocytes; Cell Transformation, Neoplastic; Chlorambucil; Cyclophosphamide; Humans; Leukemia, Ly | 1985 |
[Effect of cyclophosphane, chlorbutin and degranol on protein biosynthesis in the lymphocytes of donors and chronic lympholeukemia patients in vitro].
Topics: Alkylating Agents; Amino Acids; Blood Donors; Blood Proteins; Chlorambucil; Cyclophosphamide; Depres | 1985 |
Stimulation of D.N.A. synthesis in lymphocytes by chlorambucil.
Topics: Chlorambucil; DNA; Humans; Leukemia; Leukemia, Lymphoid; Lymphocytes | 1972 |
Studies of correlation of lymphocyte response to phytohemagglutinin with the clinical and immunologic status in chronic lymphocytic leukemia.
Topics: Cells, Cultured; Chlorambucil; DNA; Female; gamma-Globulins; Humans; Lectins; Leukemia, Lymphoid; Le | 1973 |
Letter: T-cells in chronic lymphocytic leukaemia.
Topics: Chlorambucil; Complement System Proteins; Cyclophosphamide; Erythrocytes; Follow-Up Studies; Humans; | 1974 |
[1973 treatment of acute leukemias].
Topics: Chlorambucil; Colchicine; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Dru | 1974 |
[The treatment of chronic lymphatic leukemia].
Topics: Anabolic Agents; Anemia; Anti-Bacterial Agents; Antineoplastic Agents; Blood Transfusion; Chlorambuc | 1966 |
Notes on morphologically less usual forms of chronic lymphadenosis.
Topics: Aged; Blood Cell Count; Bone Marrow Examination; Cell Nucleolus; Cell Nucleus; Cell Transformation, | 1968 |
[Richter's syndrome. 4 cases and an attempt at analysis].
Topics: Aged; Carcinoma, Squamous Cell; Chlorambucil; Cyclophosphamide; Deglutition Disorders; Drug Therapy, | 1973 |
Secondary antibody deficiency syndrome in haemoblastosis.
Topics: Agammaglobulinemia; Antibodies; Antigens, Bacterial; Blood Protein Disorders; Blood Proteins; Busulf | 1972 |
Development of acute erythroleukemia in B-cell immunoproliferative disorders after prolonged therapy with alkylating drugs.
Topics: Aged; Alkylating Agents; Biopsy; Bone Marrow; Chlorambucil; Female; Humans; Leukemia, Erythroblastic | 1974 |
[The role of deoxyribonuclease in the treatment of chronic lymphocytic leukemia].
Topics: Adult; Chlorambucil; Deoxyribonucleases; Drug Resistance; Drug Therapy, Combination; Female; Humans; | 1972 |
[Differenciation of reaction mechanisms of alkylating cytostatics on Ehrlich ascites-carcinoma- and lymphatic leucemic cells].
Topics: Alkylating Agents; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Chlorambucil; Leucine; Leukem | 1970 |
Unusual reaction to chlorambucil in a patient with chronic lymphocytic leukemia.
Topics: Chlorambucil; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Leukemia, Lymphoid; Middle Aged | 1971 |
Nephrotic syndrome in chronic lymphocytic leukaemia.
Topics: Aged; Basement Membrane; Biopsy; Blood Proteins; Bone Marrow; Chlorambucil; Complement System Protei | 1974 |
Chronic granulocytic leukaemia and chronic lymphocytic leukaemia.
Topics: Allopurinol; Amenorrhea; Busulfan; Chlorambucil; Chronic Disease; Drug Eruptions; Female; Hemolysis; | 1974 |
Biochemical and morphological observations on lymphocytes in continuous cell culture from a patient with chronic lymphocytic leukemia.
Topics: Cell Survival; Cells, Cultured; Chlorambucil; Fructose-Bisphosphate Aldolase; Glucosephosphate Dehyd | 1974 |
[Different response of the superficial and deep lymph nodes to therapy in malignant lymphoreticulopathies].
Topics: Adult; Chlorambucil; Cyclophosphamide; Female; Humans; Leukemia, Lymphoid; Lymphatic Metastasis; Lym | 1968 |
[Autoimmune hemolytic anemia with lymphatic nodules in the bone marrow].
Topics: Aged; Anemia, Hemolytic, Autoimmune; Autoantibodies; Bone Marrow; Bone Marrow Examination; Chlorambu | 1968 |
[Gastric localizations of chronic lymphoid leukemia].
Topics: Adult; Chlorambucil; Duodenal Neoplasms; Duodenal Ulcer; Gastric Mucosa; Hematemesis; Humans; Hyperp | 1969 |
[Rheumatoid polyarthritis and chronic lymphoid leukemia. Studies of 7 cases of association of these 2 diseases].
Topics: Adult; Age Factors; Aged; Animals; Antibodies; Arthritis, Rheumatoid; Autoimmune Diseases; Chlorambu | 1969 |
[Effect of various kinds of therapy on T-cell activity in chronic lymphadenosis].
Topics: Adrenocorticotropic Hormone; Aged; Cell Separation; Cells, Cultured; Chlorambucil; Cytidine; Female; | 1974 |
[Serious infectious complications of chronic lymphatic leukemia].
Topics: Chlorambucil; Chronic Disease; Female; Humans; Immunosuppression Therapy; Leukemia, Lymphoid; Middle | 1974 |
Thymic irradiation. An approach to chronic lymphocytic leukemia.
Topics: Adult; Agammaglobulinemia; Aged; Blood Platelets; Blood Protein Electrophoresis; Bone Marrow; Bone M | 1974 |
Lymphocytic.
Topics: Chlorambucil; Humans; Leukemia, Lymphoid | 1974 |
[Letter: Teratogenic effects of medications].
Topics: Abnormalities, Drug-Induced; Adult; Chlorambucil; Female; Humans; Hydroxyurea; Leukemia, Lymphoid; M | 1974 |
[Letter: Progredient liver cirrhosis in chronic lymphatic leukemia].
Topics: Chlorambucil; Diabetes Complications; Hepatitis B; Humans; Leukemia, Lymphoid; Liver Cirrhosis; Lymp | 1974 |
Chronic myelocytic and chronic lymphocytic leukemia.
Topics: Age Factors; Antilymphocyte Serum; Antineoplastic Agents; Blood Cell Count; Busulfan; Chlorambucil; | 1972 |
[Gougerot-Sjorgen's syndrome and lymphoid hemopathies].
Topics: Aged; Biopsy; Chlorambucil; Female; Humans; Leukemia, Lymphoid; Lymphography; Lymphoma; Parotid Glan | 1972 |
[Treatment of chronic leukemias].
Topics: Antineoplastic Agents; Asparaginase; Busulfan; Chlorambucil; Extracorporeal Circulation; Humans; Imm | 1973 |
Treatment of chronic lymphocytic leukemia.
Topics: Chlorambucil; Humans; Leukemia, Lymphoid; Prednisone | 1973 |
Proceedings: The chronic leukemias: current therapeutic concepts.
Topics: Bromine; Busulfan; Cell Division; Chlorambucil; Chromosome Aberrations; Cyclophosphamide; Humans; Hy | 1972 |
Chronic lymphocytic leukaemia.
Topics: Aged; B-Lymphocytes; Chlorambucil; Chronic Disease; Female; Humans; Infections; Leukemia, Lymphoid; | 1974 |
Treatment of Hodgkin's disease and other malignant lymphomas.
Topics: Alkylating Agents; Antineoplastic Agents; Carmustine; Chlorambucil; Cyclohexanes; Cyclophosphamide; | 1973 |
Effect of BCG on delayed hypersensitivity responses of patients with neoplastic disease.
Topics: Animals; Antigen-Antibody Reactions; BCG Vaccine; Cattle; Chlorambucil; Cyclophosphamide; Hodgkin Di | 1973 |
Bullous pemphigoid in chronic lymphocytic leukemia with the demonstration of antibasement membrane antibodies.
Topics: Autoantibodies; Basement Membrane; Bilirubin; Biopsy; Blood Glucose; Blood Urea Nitrogen; Chlorambuc | 1974 |
Haemolytic anaemia in malignant lymphoreticuloendothelial diseases.
Topics: Adult; Anemia, Hemolytic; Anemia, Hemolytic, Autoimmune; Autoantibodies; Bone Marrow Examination; Ce | 1974 |
Chromosomal damage induced by chlorambucil in chronic lymphocytic leukaemia.
Topics: Aged; Cell Survival; Cells, Cultured; Chlorambucil; Chromatids; Chromosome Aberrations; Chromosome D | 1972 |
The uptake and utilization of chlorambucil by lymphocytes from patients with chronic lymphocytic leukaemia.
Topics: Chlorambucil; Chronic Disease; Humans; Hydrolysis; In Vitro Techniques; Leukemia, Lymphoid; Lymphocy | 1972 |
Blastogenic transformation of lymphocytes following phytohaemagglutinin treatment in vitro in malignant lymphomas. 3. Chronic lymphatic leukaemia.
Topics: Adult; Aged; Chlorambucil; Female; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Lectins; L | 1973 |
Acute plasma cell leukaemia following chronic lymphatic leukaemia: transformation or two separate diseases?
Topics: Aged; Blood Protein Electrophoresis; Body Weight; Bone Marrow Examination; Cell Transformation, Neop | 1973 |
[Chlorambucil therapy for chronic lymphocytic leukemia].
Topics: Aged; Chlorambucil; Female; Humans; Leukemia, Lymphoid; Male; Middle Aged | 1973 |
Multiple lymphomatous polyposis of the gastrointestinal tract.
Topics: Autopsy; Biopsy; Celiac Disease; Chlorambucil; Gastrointestinal Neoplasms; Humans; Intestinal Polyps | 1973 |
Kinetics of lymphocytes in chronic lymphocytic leukemia: studies using continuous 3H-thymidine infusion in two patients.
Topics: Aged; Autoradiography; Bone Marrow Examination; Chlorambucil; Glucocorticoids; Humans; Injections, I | 1973 |
[Splenic form of lymphoid cryptoleukosis. (Apropos of a case. Observation and comments].
Topics: Aged; Chlorambucil; Female; Humans; Leukemia, Lymphoid; Radiography; Splenic Neoplasms | 1973 |
Proceedings: Bi-weekly chlorambucil treatment of chronic lymphocytic leukemia.
Topics: Chlorambucil; Digestive System; Evaluation Studies as Topic; Follow-Up Studies; Hematopoietic System | 1974 |
Metabolic complications of aggressive therapy of chronic lymphocytic leukemia.
Topics: Animals; Blood Cell Count; Blood Platelets; Blood Urea Nitrogen; Calcium; Chlorambucil; Creatinine; | 1974 |
[Fatal varicella infection in two patients with malignant systemic disease in cytostatic therapy].
Topics: Chickenpox; Chlorambucil; Hodgkin Disease; Humans; Leukemia, Lymphoid; Male; Middle Aged; Prednisone | 1974 |
Diagnosis and management of chronic lymphocytic leukemia.
Topics: Age Factors; Aged; Chlorambucil; Humans; Leukemia, Lymphoid; Male; Middle Aged; Prednisone | 1974 |
[Clinical observation of 15 patients with chronic lymphocytic leukemia--immunological aspects of C.L.L (author's transl)].
Topics: Adrenal Cortex Hormones; Adult; Aged; Chlorambucil; Female; Humans; Leukemia, Lymphoid; Male; Middle | 1974 |
Pneumocystitis carinii pneumonia: percutaneous lung biopsy and review of literature.
Topics: Adolescent; Adult; Agammaglobulinemia; Amphotericin B; Anuria; Azathioprine; Biopsy; Bis-Trimethylam | 1971 |
[Chemotherapy of chronic lymphocytic leukemia].
Topics: Antineoplastic Agents; Aziridines; Azirines; Chlorambucil; Cyclophosphamide; Humans; Leukemia, Lymph | 1967 |
[Different response of superficial and deep lymph nodes to drug therapy in malignant lymphoreticulopathy].
Topics: Aged; Chlorambucil; Cyclophosphamide; Female; Humans; Leukemia, Lymphoid; Lymph Nodes; Lymphoma, Lar | 1969 |
[Striking remission in chronic lymphatic leukemia after chlorambucil treatment during a 9-year period].
Topics: Aged; Chlorambucil; Humans; Leukemia, Lymphoid; Male; Remission, Spontaneous; Time Factors | 1972 |
Possible pulmonary effects of alkylating agents.
Topics: Alkylating Agents; Chlorambucil; Humans; Leukemia, Lymphoid; Lung; Pulmonary Fibrosis | 1972 |
Spontaneous remission of leukemic lymphoproliferative disease.
Topics: Adult; Aged; Chlorambucil; Female; Humans; Leukemia, Lymphoid; Leukocyte Count; Lymphocytes; Lymphom | 1971 |
[New formation of malignant tumors during cytostatic therapy. Case report].
Topics: Adenocarcinoma; Adrenal Cortex Hormones; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Chlo | 1971 |
A simple in-vitro test for assessing the sensitivity of lymphocytes to chlorambucil.
Topics: Aged; Chlorambucil; Chronic Disease; Drug Resistance; Female; Humans; In Vitro Techniques; Lectins; | 1971 |
[Chronic cutaneous herpes during a lymphoid blood disease treated by chemotherapy and corticoids].
Topics: Agammaglobulinemia; Chlorambucil; Herpes Simplex; Humans; Immunosuppression Therapy; Leukemia, Lymph | 1971 |
The treatment of chronic leukaemia.
Topics: Aged; Betamethasone; Busulfan; Chlorambucil; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Middle A | 1966 |
Acute leukaemia 1959-64: factors affecting prognosis.
Topics: Blood Cell Count; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Female; Humans; Leukemia; | 1968 |
Drugs in the treatment of leukemia.
Topics: Asparaginase; Busulfan; Chlorambucil; Cyclophosphamide; Cytarabine; Humans; Hydroxyurea; Leukemia; L | 1968 |
Acute leukemia occurring during chronic lymphocytic leukemia.
Topics: Adult; Aged; Bone Marrow Examination; Chlorambucil; Female; Hemoglobinometry; Humans; Leukemia; Leuk | 1970 |
Progressive vaccinia with chronic lymphatic leukaemia: a case report.
Topics: Chlorambucil; Chronic Disease; Humans; Leukemia, Lymphoid; Male; Methylprednisolone; Middle Aged; Pr | 1969 |
Palatal enlargement in chronic lymphocytic leukemia: report of case.
Topics: Aged; Chlorambucil; Edema; Humans; Leukemia, Lymphoid; Lymphatic Metastasis; Lymphoma, Non-Hodgkin; | 1970 |
The treatment of chronic leukaemia.
Topics: Antibiotics, Antineoplastic; Busulfan; Chlorambucil; Cyclophosphamide; Female; Humans; Hydroxyurea; | 1970 |
Leukemia and lymphoma.
Topics: Antineoplastic Agents; BCG Vaccine; Burkitt Lymphoma; Busulfan; Chlorambucil; Cyclophosphamide; Cyta | 1970 |
[Progress in the therapy of leukoses].
Topics: Antineoplastic Agents; Azathioprine; Busulfan; Chlorambucil; Cyclophosphamide; Daunorubicin; Humans; | 1970 |
Drug fever produced by chlorambucil.
Topics: Chlorambucil; Female; Fever; Humans; Leukemia, Lymphoid; Middle Aged | 1971 |
Pentamidine treatment of Pneumocystis carinii pneumonitis in an adult with lymphatic leukemia.
Topics: Antiprotozoal Agents; Audiometry; Chlorambucil; Fever; Humans; Leukemia, Lymphoid; Lymph Nodes; Male | 1968 |
[Use of chlorbutin in chronic lymphoid leukosis].
Topics: Aged; Chlorambucil; Female; Humans; Leukemia, Lymphoid; Male; Middle Aged | 1969 |
[A case of cutaneous leukemia].
Topics: Aged; Chlorambucil; Diagnosis, Differential; Female; Humans; Leprosy; Leukemia, Lymphoid; Skin Neopl | 1969 |
[Lysosomal enzymes in blood lymphocytes of normal subjects and patients with chronic lymphadenosis after nonspecific stimulation in vitro of short duration].
Topics: Acid Phosphatase; Blood Proteins; Chlorambucil; Glucuronidase; Humans; In Vitro Techniques; Lectins; | 1970 |
[Main problems of chronic lympheleukemia].
Topics: Adrenal Cortex Hormones; Chlorambucil; Chronic Disease; Female; Humans; Leukemia, Lymphoid; Middle A | 1970 |
Carpal tunnel syndrome in lymphatic leukemia.
Topics: Aged; Carpal Tunnel Syndrome; Chlorambucil; Edema; Humans; Leukemia, Lymphoid; Male; Prednisone | 1970 |
[Differing sensitivity to cytostatic drugs in superficial and deep groups of lymph nodes].
Topics: Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Hodgkin Disease; Humans; Leukemia, Lymphoid; | 1970 |
[Problems of rational therapeutic procedure in chronic lymphatic leukemia].
Topics: Anemia; Chlorambucil; Humans; Leukemia, Lymphoid; Pneumonia; Thrombocytopenia | 1970 |
[Duhring-Brocq disease, signal symptom of a chronic lymphoid leukemia].
Topics: Aged; Chlorambucil; Dermatitis Herpetiformis; Female; Humans; Leukemia, Lymphoid; Prednisone | 1971 |
Mu-chain disease.
Topics: Adult; Agammaglobulinemia; Anemia; Bence Jones Protein; Chlorambucil; Female; Fractures, Bone; Heavy | 1971 |
[Xanthoma plana and lymphoid leukemia].
Topics: Adult; Chlorambucil; Female; Humans; Leukemia, Lymphoid; Xanthomatosis | 1967 |
Chronic lymphocytic leukemia, Hodgkin's disease, and the nephrotic syndrome.
Topics: Blood Protein Electrophoresis; Chlorambucil; Cobalt Isotopes; Electrophoresis; Female; Hodgkin Disea | 1968 |
Chronic lymphocytic leukaemia in a child presenting at the age of two years and eight months.
Topics: Child, Preschool; Chlorambucil; Humans; Leukemia, Lymphoid; Male | 1968 |
Cold urticaria with cryoglobulinemia in a patient with chronic lymphocytic leukemia.
Topics: Basophils; Blood Protein Electrophoresis; Blood Proteins; Chlorambucil; Chronic Disease; Cold Temper | 1968 |
Chronic lymphatic leukemia in the older patient.
Topics: Aged; Anemia; Chlorambucil; Diagnosis, Differential; Humans; Infections; Leukemia, Lymphoid; Lymphat | 1968 |
Infiltration of the iris in chronic lymphatic leukaemia.
Topics: Acetazolamide; Chlorambucil; Chronic Disease; Glaucoma; Humans; Intraocular Pressure; Iris; Leukemia | 1968 |
[Disseminated zona and chronic lymphoid leukemia (2 cases)].
Topics: Aged; Chlorambucil; Drug Synergism; Female; Herpes Zoster; Humans; Leukemia, Lymphoid; Male; Middle | 1968 |
Acropachy in lymphatic leukemia.
Topics: Adult; Bone Marrow Examination; Chlorambucil; Hand; Humans; Leukemia, Lymphoid; Male; Osteoarthropat | 1969 |
Comparison of chlorambucil and streptonigrin (NSC-45383) in the treatment of chronic lymphocytic leukemia.
Topics: Antibiotics, Antineoplastic; Chlorambucil; Humans; Leukemia, Lymphoid; Middle Aged; Picolinic Acids; | 1969 |
Lymphatic leukemia for perhaps 28 years.
Topics: Adult; Chlorambucil; Female; Hematocrit; Humans; Leukemia, Lymphoid; Leukocyte Count; Lymphocytes; M | 1969 |
Recurrent leukaemoid reaction in pernicious anaemia complicated by gastric carcinoma.
Topics: Adenocarcinoma; Anemia, Pernicious; Chlorambucil; Chronic Disease; Diagnosis, Differential; Female; | 1969 |
[Some reflections on the favorable effects of chlorambucil in unusual doses].
Topics: Aged; Chlorambucil; Female; Humans; In Vitro Techniques; Leukemia, Lymphoid; Lymphoma, Non-Hodgkin; | 1965 |
X-radiation and alkylating agents as possible "trigger" mechanisms in the autoimmune complications of malignant lymphophroliferative disease.
Topics: Adult; Aged; Anemia, Hemolytic, Autoimmune; Chlorambucil; Humans; Leukemia, Lymphoid; Lymphoma, Non- | 1966 |