chlorambucil has been researched along with Kidney Diseases in 31 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of chlorambucil treatment in a group of six patients diagnosed by renal biopsy of renal amyloidosis secondary to rheumatoid arthritis was evaluated." | 7.70 | [Treatment with chlorambucil of renal amyloidosis secondary to rheumatoid arthritis. Study of 6 cases]. ( Alvarez Vega, JL; Arrobas, M; Robles, NR; Roncero, F; Sánchez Casado, E, 1999) |
| "The effect of chlorambucil treatment in a group of six patients diagnosed by renal biopsy of renal amyloidosis secondary to rheumatoid arthritis was evaluated." | 3.70 | [Treatment with chlorambucil of renal amyloidosis secondary to rheumatoid arthritis. Study of 6 cases]. ( Alvarez Vega, JL; Arrobas, M; Robles, NR; Roncero, F; Sánchez Casado, E, 1999) |
| "Psoriatic spondyloarthropathy (PSA) can occasionally be complicated by AA amyloid, and renal amyloidosis should be suspected in patients with PSA who have unexplained proteinuria." | 1.32 | Cytostatic therapy for AA amyloidosis complicating psoriatic spondyloarthropathy. ( Hawkins, PN; Moots, RJ; Mpofu, S; Smith, PJ; Teh, LS, 2003) |
| "Chlorambucil (CHL) was administered ip on d 11 of gestation at doses of 0, 3, and 6 mg/kg; nitrofen (2,4-dichlorophenyl p-nitrophenyl ether) (NIT) was given po on d 8-16 of gestation at 0, 4." | 1.27 | Morphometric, biochemical, and physiological assessment of perinatally induced renal dysfunction. ( Gray, JA; Kavlock, RJ, 1983) |
| "Chlorambucil alone was given in 14 treatment periods, cyclophosphamide alone in six, and both alternately in two." | 1.27 | Alkylating cytostatic treatment in renal amyloidosis secondary to rheumatic disease. ( Berglund, K; Keller, C; Thysell, H, 1987) |
| "Chlorambucil was used as a standard at dose levels of 1, 5 and 10 mg/kg/day." | 1.27 | Toxicity of the alkylating agent bendamustin. ( Güttner, J; Härtl, A; Hoffmann, H; Horn, U, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (61.29) | 18.7374 |
| 1990's | 6 (19.35) | 18.2507 |
| 2000's | 6 (19.35) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Millet, A | 1 |
| Rioux-Leclercq, N | 1 |
| Le Lay, JP | 1 |
| Le Pogamp, P | 1 |
| Vigneau, C | 1 |
| Mpofu, S | 1 |
| Teh, LS | 1 |
| Smith, PJ | 1 |
| Moots, RJ | 1 |
| Hawkins, PN | 1 |
| Ben Ghorbel, I | 1 |
| Khanfir, M | 1 |
| Houman, MH | 1 |
| Balakrishnan, C | 1 |
| Pathan, E | 1 |
| Khodaiji, S | 1 |
| Dasgupta, A | 1 |
| Mangat, G | 1 |
| Joshi, VR | 1 |
| Kavlock, RJ | 1 |
| Gray, JA | 1 |
| Geltner, D | 1 |
| Kohn, RW | 1 |
| Gorevic, P | 1 |
| Franklin, EC | 1 |
| Plaza de los Reyes, M | 1 |
| Lazcano, F | 1 |
| Passalacqua, W | 1 |
| Plaza de los Reyes, X | 1 |
| Saffie, A | 1 |
| de Croizet, V | 1 |
| Donadio, JV | 1 |
| Fitzgerald, RH | 1 |
| Wallace, KM | 1 |
| Baker, AS | 1 |
| Pispirigos, K | 1 |
| Catsoulakos, P | 1 |
| Karakiulakis, G | 1 |
| Berglund, K | 3 |
| Thysell, H | 3 |
| Keller, C | 2 |
| Robles, NR | 1 |
| Roncero, F | 1 |
| Arrobas, M | 1 |
| Alvarez Vega, JL | 1 |
| Sánchez Casado, E | 1 |
| Pearson, TC | 1 |
| Messinezy, M | 1 |
| Ortiz-Santamaría, V | 1 |
| Olivé, A | 1 |
| Valls-Roc, M | 1 |
| Tena, X | 1 |
| Hagge, W | 1 |
| Maugars, Y | 1 |
| Couverchel, L | 1 |
| Guenel, Y | 1 |
| Bureau, L | 1 |
| Buzelin, F | 1 |
| Prost, A | 1 |
| Deschênes, G | 1 |
| Prieur, AM | 1 |
| Hayem, F | 1 |
| Broyer, M | 1 |
| Gubler, MC | 1 |
| Horn, U | 1 |
| Härtl, A | 1 |
| Güttner, J | 1 |
| Hoffmann, H | 1 |
| Sukenik, S | 1 |
| Buskila, D | 1 |
| Horowitz, I | 1 |
| Maroko, I | 1 |
| Méry, JP | 1 |
| Girard, JF | 1 |
| Skinner, MD | 1 |
| Schwartz, RS | 1 |
| Kaplan, SR | 1 |
| Calabresi, P | 1 |
| Presant, CA | 1 |
| Wiernik, PH | 1 |
| Serpick, AA | 1 |
| Petrányi, G | 1 |
| Leövey, A | 1 |
| Szegedi, G | 1 |
| Kakuk, G | 1 |
| Bobory, J | 1 |
| Zosin, C | 1 |
| Mănescu, N | 1 |
| Iacob, G | 1 |
| Schwarzkopf, A | 1 |
| Sabo, I | 1 |
| Gluhovschi, G | 1 |
| Lagrue, G | 2 |
| Bariéty, J | 2 |
| Vissian, L | 1 |
| Martin, J | 1 |
| Vaillaud, JC | 1 |
| Milliez, P | 1 |
| Schwalbová, M | 1 |
| Krajci-Lazáryová, M | 1 |
| Misíková, Z | 1 |
5 reviews available for chlorambucil and Kidney Diseases
| Article | Year |
|---|---|
Idiopathic erythrocytosis, diagnosis and clinical management.
Topics: Aged; Arterial Occlusive Diseases; Bone Marrow; Chlorambucil; Diagnosis, Differential; Endocrine Sys | 2001 |
[Haematuria in children. III. Treatment of glomerular diseases (author's transl)].
Topics: Acute Kidney Injury; Adrenal Cortex Hormones; Child; Chlorambucil; Cyclophosphamide; Glomerulonephri | 1978 |
[Renal amyloidosis in rheumatoid polyarthritis stabilized for 13 years with chlorambucil].
Topics: Amyloidosis; Arthritis, Rheumatoid; Chlorambucil; Female; Humans; Kidney Diseases; Middle Aged; Time | 1990 |
Immunosuppressive therapy. 2.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Adult; Azathioprine; Child; Chlorambucil; Clin | 1972 |
Drug therapy. Immunosuppressive agents. I.
Topics: Adrenal Cortex Hormones; Adult; Alkylating Agents; Antimetabolites; Arthritis, Rheumatoid; Autoimmun | 1973 |
1 trial available for chlorambucil and Kidney Diseases
| Article | Year |
|---|---|
Immunosuppressive therapy. 2.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Adult; Azathioprine; Child; Chlorambucil; Clin | 1972 |
26 other studies available for chlorambucil and Kidney Diseases
| Article | Year |
|---|---|
Unexpected remission of renal AA amyloidosis associated with rheumatoid arthritis.
Topics: Adult; Amyloidosis; Antineoplastic Agents, Alkylating; Arthritis, Rheumatoid; Chlorambucil; Female; | 2009 |
Cytostatic therapy for AA amyloidosis complicating psoriatic spondyloarthropathy.
Topics: Amyloidosis; Arthritis, Psoriatic; Chlorambucil; Follow-Up Studies; Humans; Kidney Diseases; Male; M | 2003 |
[Amyloidosis in adult onset Still's disease].
Topics: Adrenal Cortex Hormones; Adult; Age Factors; Amyloidosis; Chlorambucil; Colchicine; Drug Therapy, Co | 2004 |
Myelodysplasia and acute myeloid leukaemia in a case of rheumatoid arthritis with secondary amyloidosis treated with chlorambucil.
Topics: Acute Disease; Amyloidosis; Antirheumatic Agents; Arthritis, Rheumatoid; Chlorambucil; Fatal Outcome | 2004 |
Morphometric, biochemical, and physiological assessment of perinatally induced renal dysfunction.
Topics: Age Factors; Animals; Animals, Newborn; Chlorambucil; Deamino Arginine Vasopressin; Diuresis; Dogs; | 1983 |
The effect of combination therapy (steroids, immunosuppressives, and plasmapheresis) on 5 mixed cryoglobulinemia patients with renal, neurologic, and vascular involvement.
Topics: Aged; Chlorambucil; Cryoglobulinemia; Female; Humans; Kidney Diseases; Male; Middle Aged; Paraprotei | 1981 |
[Combination therapy with prednisone, chlorambucil, dipyridamole and aspirin in various glomerular diseases. Experience with 33 patients].
Topics: Aspirin; Chlorambucil; Dipyridamole; Drug Therapy, Combination; Humans; Kidney Diseases; Prednisone | 1983 |
Primary glomerular disease: to treat or not to treat.
Topics: Azathioprine; Chlorambucil; Cyclophosphamide; Dipyridamole; Glomerulonephritis; Glomerulosclerosis, | 1982 |
Acute obstructive uric acid nephropathy after treatment of neoplastic adenopathy.
Topics: Acute Disease; Chlorambucil; Constriction, Pathologic; Female; Humans; Kidney Diseases; Leukemia, Ly | 1981 |
Evaluation of kidney and liver subacute toxicity of antitumor agents using serum biochemical parameters in rats.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antineoplastic Agents; Aspartate Aminotransfera | 1993 |
Results, principles and pitfalls in the management of renal AA-amyloidosis; a 10-21 year followup of 16 patients with rheumatic disease treated with alkylating cytostatics.
Topics: Albumins; Amyloidosis; Antineoplastic Agents; C-Peptide; Chlorambucil; Creatinine; Cyclophosphamide; | 1993 |
Renal amyloidosis secondary to chronic rheumatic inflammatory disease.
Topics: Amyloidosis; Antineoplastic Agents, Alkylating; Chlorambucil; Chronic Disease; Humans; Kidney Diseas | 1996 |
[Treatment with chlorambucil of renal amyloidosis secondary to rheumatoid arthritis. Study of 6 cases].
Topics: Adult; Aged; Amyloidosis; Antineoplastic Agents, Alkylating; Arthritis, Rheumatoid; Biopsy; Chloramb | 1999 |
Treatment of AA amyloid with chlorambucil.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amyloidosis; Child; Chlorambucil; Creatinine; Female; Hu | 2002 |
Renal amyloidosis in juvenile chronic arthritis: evolution after chlorambucil treatment.
Topics: Amyloidosis; Arthritis, Juvenile; Biopsy; Chlorambucil; Follow-Up Studies; Humans; Kidney Diseases; | 1990 |
Alkylating cytostatic treatment in renal amyloidosis secondary to rheumatic disease.
Topics: Adult; Amyloidosis; Chlorambucil; Cyclophosphamide; Female; Humans; Kidney; Kidney Diseases; Male; R | 1987 |
Toxicity of the alkylating agent bendamustin.
Topics: Alkylating Agents; Animals; Atrophy; Bendamustine Hydrochloride; Body Weight; Chlorambucil; Digestiv | 1985 |
[Renal amylosis and juvenile rheumatoid polyarthritis. Value of chlorambucil].
Topics: Adult; Amyloidosis; Arthritis, Juvenile; Chlorambucil; Humans; Kidney Diseases; Male | 1985 |
[Indications for immunosuppressive agents in glomerular nephropathies].
Topics: Adrenal Cortex Hormones; Anti-Glomerular Basement Membrane Disease; Azathioprine; Chlorambucil; Cycl | 1974 |
Disseminated extrapulmonary nocardiosis presenting as a renal abscess.
Topics: Abscess; Adult; Anemia, Hemolytic, Autoimmune; Autopsy; Brain Diseases; Chlorambucil; Diagnosis, Dif | 1970 |
Therapy of autoimmune nephropathy with steroids and cytostatics. A follow-up study of 80 patients and of 16 years.
Topics: Adolescent; Adult; Aged; Antimalarials; Autoimmune Diseases; Azathioprine; Chlorambucil; Cyclophosph | 1971 |
[Immunodepressive therapy in nephropathies].
Topics: Azathioprine; Chlorambucil; Collagen Diseases; Diabetic Nephropathies; Glomerulonephritis; Humans; I | 1969 |
[Primary glomerulopathies--therapy using corticosteroids and cytostatics (immunosuppressive agents)].
Topics: Antineoplastic Agents; Azathioprine; Chlorambucil; Glomerulonephritis; Humans; Immunosuppressive Age | 1970 |
[Lyell's syndrome observed during immunosuppressive treatment].
Topics: Adolescent; Chlorambucil; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Skin Diseases; St | 1968 |
[Lupus nephropathies and their treatment].
Topics: Chlorambucil; Glomerulonephritis; Humans; Kidney Diseases; Lupus Erythematosus, Systemic; Prednisolo | 1968 |
[Immunosuppresive agents in the treatment of nephropathies of children].
Topics: Azathioprine; Child; Chlorambucil; Cyclophosphamide; Humans; Immunosuppressive Agents; Kidney Diseas | 1969 |