chlorambucil has been researched along with Inappropriate ADH Syndrome in 1 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Inappropriate ADH Syndrome: A condition of HYPONATREMIA and renal salt loss attributed to overexpansion of BODY FLUIDS resulting from sustained release of ANTIDIURETIC HORMONES which stimulates renal resorption of water. It is characterized by normal KIDNEY function, high urine OSMOLALITY, low serum osmolality, and neurological dysfunction. Etiologies include ADH-producing neoplasms, injuries or diseases involving the HYPOTHALAMUS, the PITUITARY GLAND, and the LUNG. This syndrome can also be drug-induced.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe a patient with chronic lymphocytic leukemia, without evidence of central nervous system involvement, who suffered from SIADH presumably caused by small doses of chlorambucil." | 1.30 | Chlorambucil-induced inappropriate antidiuresis in a man with chronic lymphocytic leukemia. ( Brunet, S; Ortega, E; Puig, J; Puig, M; Subirà, M; Wägner, AM, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wägner, AM | 1 |
| Brunet, S | 1 |
| Puig, J | 1 |
| Ortega, E | 1 |
| Subirà, M | 1 |
| Puig, M | 1 |
1 other study available for chlorambucil and Inappropriate ADH Syndrome
| Article | Year |
|---|---|
Chlorambucil-induced inappropriate antidiuresis in a man with chronic lymphocytic leukemia.
Topics: Antineoplastic Agents, Alkylating; Chlorambucil; Humans; Inappropriate ADH Syndrome; Leukemia, Lymph | 1999 |