chlorambucil has been researched along with Hypospermatogenesis in 9 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the gonadal effects of chlorambucil given to prepubertal and pubertal boys, testicular function of 21 adolescents or young men, treated with chlorambucil for nephrotic syndrome before or during puberty, have been evaluated." | 7.66 | Gonadal effects of chlorambucil given to prepubertal and pubertal boys for nephrotic syndrome. ( Broyer, M; Guesry, P; Lenoir, G, 1978) |
| "Biochemical analysis and morphological studies were carried out in six patients with lymphomas during and after withdrawal treatment with chlorambucil, testosterone propionate (TP) and human chorionic gonadotropins (HCG)." | 3.66 | Biochemical changes of the human semen produced by chlorambucil, testosterone propionate and human chorionic gonadotropin administration. ( Calamera, JC; Mancini, RE; Morgenfeld, MC; Vilar, O, 1979) |
| "To assess the gonadal effects of chlorambucil given to prepubertal and pubertal boys, testicular function of 21 adolescents or young men, treated with chlorambucil for nephrotic syndrome before or during puberty, have been evaluated." | 3.66 | Gonadal effects of chlorambucil given to prepubertal and pubertal boys for nephrotic syndrome. ( Broyer, M; Guesry, P; Lenoir, G, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pasqualini, T | 1 |
| Tabbara, KF | 1 |
| Shafford, EA | 1 |
| Kingston, JE | 1 |
| Malpas, JS | 1 |
| Plowman, PN | 1 |
| Pritchard, J | 1 |
| Savage, MO | 1 |
| Eden, OB | 1 |
| Zhang, WZ | 1 |
| Wang, SH | 1 |
| Calamera, JC | 1 |
| Morgenfeld, MC | 1 |
| Mancini, RE | 1 |
| Vilar, O | 1 |
| Guesry, P | 1 |
| Lenoir, G | 1 |
| Broyer, M | 1 |
| Marmor, D | 1 |
| Grob-Menendez, F | 1 |
| Duyck, F | 1 |
| Delafontaine, D | 1 |
| Brenner, J | 1 |
| Vugrin, D | 1 |
| Whitmore, WF | 1 |
| Kalinicheva, EO | 1 |
| Papaian, AV | 1 |
1 review available for chlorambucil and Hypospermatogenesis
| Article | Year |
|---|---|
[Effect of cytostatic preparations used in the treatment of glomerulonephritis in children on the functional activity of the gonads].
Topics: Amenorrhea; Chlorambucil; Cyclophosphamide; Female; Humans; Male; Nephrosis, Lipoid; Oligospermia | 1987 |
8 other studies available for chlorambucil and Hypospermatogenesis
| Article | Year |
|---|---|
[Testicular damage caused by chemotherapy in acute lymphoblastic leukemia].
Topics: Adolescent; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; C | 1983 |
Chlorambucil in Behçet's disease. A reappraisal.
Topics: Adolescent; Adult; Atrophy; Behcet Syndrome; Chlorambucil; Drug Administration Schedule; Humans; Mal | 1983 |
Testicular function following the treatment of Hodgkin's disease in childhood.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined Modality Therapy; | 1993 |
[Remote effect of Tripterygium wilfordii and chlorambucil on the function of sex glands of child with nephropathy].
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Drugs, Chinese Herbal; Female; Follicle Stimulati | 1996 |
Biochemical changes of the human semen produced by chlorambucil, testosterone propionate and human chorionic gonadotropin administration.
Topics: Adolescent; Adult; Cell Count; Chlorambucil; Chorionic Gonadotropin; Citrates; Fructose; Humans; Lym | 1979 |
Gonadal effects of chlorambucil given to prepubertal and pubertal boys for nephrotic syndrome.
Topics: Adolescent; Cell Count; Child; Chlorambucil; Follicle Stimulating Hormone; Humans; Luteinizing Hormo | 1978 |
Very late return of spermatogenesis after chlorambucil therapy: case reports.
Topics: Adult; Chlorambucil; Humans; Male; Oligospermia; Spermatogenesis; Time Factors | 1992 |
Effect of treatment on fertility and sexual function in males with metastatic nonseminomatous germ cell tumors of testis.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplati | 1985 |