chlorambucil has been researched along with Hydatidiform Mole in 14 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Hydatidiform Mole: Trophoblastic hyperplasia associated with normal gestation, or molar pregnancy. It is characterized by the swelling of the CHORIONIC VILLI and elevated human CHORIONIC GONADOTROPIN. Hydatidiform moles or molar pregnancy may be categorized as complete or partial based on their gross morphology, histopathology, and karyotype.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Surgery combined with chemotherapy was applied in 34 out of 178 patients (19." | 1.29 | Chemotherapy combined with surgery in the treatment of gestational trophoblastic disease (GTD). ( Kietlińska, Z; Sablińska, B; Zieliński, J, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (85.71) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hammond, CB | 3 |
| Olt, GJ | 1 |
| Sablińska, B | 1 |
| Kietlińska, Z | 1 |
| Zieliński, J | 1 |
| Jones, WB | 1 |
| Lewis, JL | 1 |
| Lehr, M | 1 |
| Becker, RL | 1 |
| Avioli, LV | 1 |
| Tscherne, G | 1 |
| Takamizawa, H | 1 |
| Sekiya, S | 1 |
| Kobayashi, O | 1 |
| Matsui, H | 1 |
| Lajos, L | 1 |
| Székely, J | 1 |
| Major, A | 1 |
| Balogh, S | 1 |
| Bücs, G | 1 |
| Bret, AJ | 1 |
| Grépinet, J | 1 |
| Parker, RT | 2 |
| Li, MC | 1 |
| Bloomfield, RD | 1 |
| Borchert, LG | 1 |
| Tyrey, L | 1 |
| Creasman, WT | 1 |
| Sandström, B | 1 |
| Jacobs, EM | 1 |
| Johnson, FD | 1 |
3 reviews available for chlorambucil and Hydatidiform Mole
| Article | Year |
|---|---|
[New aspects of diagnosis, treatment and follow-up of trophoblastic tumours (author's transl)].
Topics: Adult; Aftercare; Brain Neoplasms; Chlorambucil; Chorionic Gonadotropin; Dactinomycin; Drug Therapy, | 1979 |
Trophoblastic disease: natural history, diagnosis, and treatment.
Topics: Alkylating Agents; Aminopterin; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; | 1971 |
Current cancer chemotherapy in obstetrics and gynecology.
Topics: Alkaloids; Alkylating Agents; Anti-Bacterial Agents; Antimetabolites; Blood Cell Count; Bone Marrow; | 1971 |
11 other studies available for chlorambucil and Hydatidiform Mole
| Article | Year |
|---|---|
Gestational trophoblastic disease.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug A | 1994 |
Chemotherapy combined with surgery in the treatment of gestational trophoblastic disease (GTD).
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Chorioca | 1993 |
Monitor of chemotherapy in gestational trophoblastic neoplasm by radioimmunoassay of the beta-subunit of human chorionic gonadotropin.
Topics: Adult; Antineoplastic Agents; Biological Assay; Bleomycin; Chlorambucil; Choriocarcinoma; Chorionic | 1975 |
Gestational trophoblastic disease.
Topics: Adult; Brain Neoplasms; Cerebral Hemorrhage; Chlorambucil; Choriocarcinoma; Dactinomycin; Female; He | 1977 |
Chemotherapy for gestational trophoblastic tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropi | 1987 |
[Importance of chemotherapeutic agents in the treatment of malignant trophoblast tumors].
Topics: Adnexa Uteri; Adult; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; Female; Hu | 1969 |
[Uterine chorioepithelioma].
Topics: Abortion, Spontaneous; Adult; Antineoplastic Agents; Chlorambucil; Chloramines; Choriocarcinoma; Dac | 1966 |
Diagnosis and treatment of trophoblastic disease. A report from the Southeastern Regional Center.
Topics: Adult; Antineoplastic Agents; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; D | 1970 |
Treatment of metastatic trophoblastic disease: good and poor prognosis.
Topics: Brain Neoplasms; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; Female; Follow | 1973 |
[Malignant mole and choriocarcinoma].
Topics: Chlorambucil; Choriocarcinoma; Female; Humans; Hydatidiform Mole; Methotrexate; Pregnancy; Prognosis | 1973 |
Gestational choriocarcinoma.
Topics: Adult; California; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; Female; Huma | 1972 |