chlorambucil has been researched along with Hormone-Dependent Neoplasms in 2 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Three human breast carcinoma xenografts, MCF-7, R-27 and T-61 serially transplanted into nude mice were treated with mitomycin C (MMC) alone, KM2210 (estra-1, 3, 5(10)-triene-3, 17 beta-diol, 3 benzoate 17-[4-(4-bis(2-chloroethyl)amino)phenyl)-1-oxobutoxy)acetate) alone and KM2210 followed by MMC." | 1.28 | [Enhancement of antitumor activity of mitomycin C against human breast carcinoma xenografts by pretreatment with KM 2210]. ( Arisawa, Y; Fujita, S; Inoue, S; Ishibiki, K; Josui, K; Kubota, T; Kuzuoka, M; Oka, S; Suto, A; Yamamoto, T, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Berry, WR | 1 |
| Yamamoto, T | 1 |
| Kubota, T | 1 |
| Oka, S | 1 |
| Josui, K | 1 |
| Fujita, S | 1 |
| Arisawa, Y | 1 |
| Suto, A | 1 |
| Inoue, S | 1 |
| Kuzuoka, M | 1 |
| Ishibiki, K | 1 |
2 other studies available for chlorambucil and Hormone-Dependent Neoplasms
| Article | Year |
|---|---|
Re-induction of hormonal sensitivity in hormone-refractory prostate cancer--fact or fiction?
Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Clinical Trials as Topic; Drug Resista | 2005 |
[Enhancement of antitumor activity of mitomycin C against human breast carcinoma xenografts by pretreatment with KM 2210].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chlorambucil; Estradiol; | 1990 |