chlorambucil has been researched along with Head and Neck Neoplasms in 4 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Head and Neck Neoplasms: Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the absence of evidence of a dose-response curve for platinum, the lower dosage schedules that can be used with acceptable toxicity on an outpatient basis should be selected." | 3.75 | Chemotherapy for squamous cell carcinoma of the head and neck: a progress report. ( Glick, JH; Taylor, SG; Zehngebot, LM, 1980) |
| "35 cases of non-Hodgkin malignant lymphomas of head and neck, stages I and II." | 1.27 | [Non-Hodgkin lymphomas of the head and neck, stages I and II. Apropos 35 cases]. ( Beral, HM; Bertrand, JC; Chantelar, JV; Ghenim, C; Guerin, RA; Guilbert, F; Nizri, D; Szpirglas, H; Touboul, E; Zribi, A, 1985) |
| "Head and neck carcinomas and breast cancer had the highest incidence (5 and 3 cases, respectively)." | 1.26 | Primary malignant neoplasms associated with chronic lymphocytic leukemia. ( Franchi, F; Monfardini, S; Rilke, F; Santoro, A, 1980) |
| "Generally, metastases responded better than the advanced primaries from which they were derived, except for those from breast tumours." | 1.25 | The influence of site of metastasis on tumour growth and response to chemotherapy. ( Bross, ID; Slack, NH, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Glick, JH | 1 |
| Zehngebot, LM | 1 |
| Taylor, SG | 1 |
| Santoro, A | 1 |
| Rilke, F | 1 |
| Franchi, F | 1 |
| Monfardini, S | 1 |
| Slack, NH | 1 |
| Bross, ID | 1 |
| Touboul, E | 1 |
| Ghenim, C | 1 |
| Chantelar, JV | 1 |
| Nizri, D | 1 |
| Zribi, A | 1 |
| Guerin, RA | 1 |
| Guilbert, F | 1 |
| Bertrand, JC | 1 |
| Szpirglas, H | 1 |
| Beral, HM | 1 |
1 review available for chlorambucil and Head and Neck Neoplasms
| Article | Year |
|---|---|
Chemotherapy for squamous cell carcinoma of the head and neck: a progress report.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil; Clinical Trials as Topic; | 1980 |
1 trial available for chlorambucil and Head and Neck Neoplasms
| Article | Year |
|---|---|
Chemotherapy for squamous cell carcinoma of the head and neck: a progress report.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil; Clinical Trials as Topic; | 1980 |
3 other studies available for chlorambucil and Head and Neck Neoplasms
| Article | Year |
|---|---|
Primary malignant neoplasms associated with chronic lymphocytic leukemia.
Topics: Breast Neoplasms; Chlorambucil; Colonic Neoplasms; Cyclophosphamide; Female; Head and Neck Neoplasms | 1980 |
The influence of site of metastasis on tumour growth and response to chemotherapy.
Topics: Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Female; Fluorouracil; Genital Neoplasms, Fema | 1975 |
[Non-Hodgkin lymphomas of the head and neck, stages I and II. Apropos 35 cases].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined Modality Therapy | 1985 |