chlorambucil has been researched along with Hand-Schu00FCller-Christian Disease in 13 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A prospective study for histiocytosis X was designed to determine whether "good risk" patients, ie, those without evidence of dysfunction of liver, lung, or hemopoietic system, would respond to single agent therapy; in this case chlorambucil (CMB) used in a dose of 5 mgm/m2/day." | 2.65 | Histiocytosis X: clinical trial of chlorambucil: a report from Childrens Cancer Study Group. ( Hammond, D; Heyn, RM; Lahey, ME; Leikin, S; Newton, WA; Shore, N; Smith, WB, 1979) |
| "We describe two cases of Hodgkin's disease after heart and heart/lung transplants respectively." | 1.29 | Hodgkin's disease after cardiac transplant: a report of two cases. ( Hood, IM; Mahendra, P; Marcus, RE; McNeil, K, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (92.31) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pastor Durán, X | 1 |
| Palomeque Rico, A | 1 |
| Cruz Hernández, M | 1 |
| Nagata, Y | 1 |
| Miwa, A | 1 |
| Murai, Y | 1 |
| Mori, M | 1 |
| Yamamoto, T | 1 |
| Karbe, S | 1 |
| Koike, N | 1 |
| Starling, KA | 1 |
| Iyer, R | 1 |
| Silva-Sosa, M | 1 |
| Komp, D | 1 |
| Herson, J | 1 |
| Trueworthy, RC | 1 |
| Hood, IM | 1 |
| Mahendra, P | 1 |
| McNeil, K | 1 |
| Marcus, RE | 1 |
| Lahey, ME | 1 |
| Heyn, RM | 1 |
| Newton, WA | 1 |
| Shore, N | 1 |
| Smith, WB | 1 |
| Leikin, S | 1 |
| Hammond, D | 1 |
| Mahoney, DH | 1 |
| McClain, KL | 1 |
| Hanson, IC | 1 |
| Taylor, LD | 1 |
| Steuber, CP | 1 |
| Donat, J | 1 |
| Fernández-Delgado, R | 1 |
| Fernández, L | 1 |
| Jubert, A | 1 |
| Kritharides, L | 1 |
| Lawrie, K | 1 |
| Varigos, GA | 1 |
| Rossier, A | 1 |
| De Kraker, J | 1 |
| Voûte, PA | 1 |
| Van Putten, WJ | 1 |
| Delemarre, JF | 1 |
| Marie, J | 1 |
| Hennequet, A | 1 |
| Lévêque, B | 1 |
| Debauchez, C | 1 |
| Desbois, C | 1 |
| Watchi, JM | 1 |
| Appalanarasayya, K | 1 |
| Devi, OB | 1 |
| Drescher, J | 1 |
1 trial available for chlorambucil and Hand-Schu00FCller-Christian Disease
| Article | Year |
|---|---|
Histiocytosis X: clinical trial of chlorambucil: a report from Childrens Cancer Study Group.
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Clinical Trials as Topic; Female; Histiocytosis, | 1979 |
12 other studies available for chlorambucil and Hand-Schu00FCller-Christian Disease
| Article | Year |
|---|---|
[Histiocytosis X with thyroid involvement].
Topics: Child, Preschool; Chlorambucil; Combined Modality Therapy; Ear Diseases; Histiocytosis, Langerhans-C | 1984 |
[A case of Hand-Schüller-Christian disease with foam cells in the pericardial effusion treated effectively by KM 2210].
Topics: Adult; Chlorambucil; Estradiol; Female; Foam Cells; Histiocytosis, Langerhans-Cell; Humans; Macropha | 1982 |
Chlorambucil in histiocytosis X: a Southwest Oncology Group study.
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Drug Evaluation; Drug Therapy, Combination; Histi | 1980 |
Hodgkin's disease after cardiac transplant: a report of two cases.
Topics: Adult; Antibodies, Viral; Antineoplastic Combined Chemotherapy Protocols; Aspergillosis; Chlorambuci | 1996 |
Acquired immune deficiency, myelodysplasia, and acute nonlymphocytic leukemia associated with monosomy 7 and t(3;3) (q21;q26) in a child with Langerhans cell histiocytosis.
Topics: Chlorambucil; Chromosome Deletion; Chromosomes, Human, Pair 3; Chromosomes, Human, Pair 7; Female; H | 1989 |
[Histiocytosis X: localized and disseminated forms. Apropos of 13 cases].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child, Preschool; Chlorambucil; Comb | 1986 |
Cyclophosphamide hypersensitivity and cross-reactivity with chlorambucil.
Topics: Adult; Chlorambucil; Cross Reactions; Cyclophosphamide; Drug Hypersensitivity; Female; Histiocytosis | 1987 |
[Trial therapy of reticulosis X].
Topics: Adrenocorticotropic Hormone; Aminopterin; Chlorambucil; Cortisone; Eosinophilic Granuloma; Glucocort | 1969 |
[Eosinophilic granuloma].
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Eosinophilic Granuloma; Histiocytes; Histiocytosi | 1974 |
[Histiocytic reticulosis in infants or Letterer-Siwe disease. (Clinical and therapeutical study)].
Topics: Acrodermatitis; Betamethasone; Biopsy; Blood Cell Count; Bone Diseases; Child, Preschool; Chlorambuc | 1968 |
Hand-Schueller-Christian disease. Report of a case and review of the literature.
Topics: Biopsy; Child, Preschool; Chlorambucil; Cyclophosphamide; Granuloma; Histiocytes; Histiocytosis, Lan | 1970 |
[Hand-Schüller-Christian disease].
Topics: Child, Preschool; Chlorambucil; Cyclophosphamide; Histiocytosis, Langerhans-Cell; Humans; Mercaptopu | 1971 |