chlorambucil has been researched along with Graves Disease in 5 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Graves Disease: A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Graves' disease was initially diagnosed in an 11-year-old Chinese boy in March 1989." | 1.28 | Class IV lupus nephritis associated with Graves' disease. ( Chao, T; Chen, WP; Fu, LS; Lin, CY; Ooi, SK; Yang, LY, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kuenn, JW | 1 |
| Weber, R | 1 |
| Teague, PO | 1 |
| Keitt, AS | 1 |
| Fu, LS | 1 |
| Yang, LY | 1 |
| Chen, WP | 1 |
| Chao, T | 1 |
| Ooi, SK | 1 |
| Lin, CY | 1 |
| Bonnet, M | 1 |
| Laroche, C | 1 |
| Caquet, R | 1 |
| Remy, JM | 1 |
| Depisch, D | 1 |
| Höfer, R | 1 |
| Schatz, H | 1 |
1 review available for chlorambucil and Graves Disease
| Article | Year |
|---|---|
[Immunodepressors in ophthalmology].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Antibiotics, Antineoplastic; Antilymphocyte Se | 1971 |
4 other studies available for chlorambucil and Graves Disease
| Article | Year |
|---|---|
Cryopathic gangrene with an IgM lambda cryoprecipitating cold agglutinin.
Topics: Adult; Agglutinins; Autoantibodies; Breast Neoplasms; Chlorambucil; Cryoglobulins; Female; Gangrene; | 1978 |
Class IV lupus nephritis associated with Graves' disease.
Topics: Carbimazole; Child; Chlorambucil; Graves Disease; Humans; Lupus Nephritis; Male; Prednisolone; Propy | 1992 |
[Acute erythroleukemia following treatment of malignant exophthalmos with chlorambucil].
Topics: Acute Disease; Aged; Chlorambucil; Female; Graves Disease; Humans; Leukemia, Erythroblastic, Acute; | 1972 |
[The effect of immunosuppressive therapy on the long acting thyroid stimulator (LATS) and the clinical picture in patients with localized myxedema and exophthalmus].
Topics: Chlorambucil; Graves Disease; Humans; Immunosuppressive Agents; Long-Acting Thyroid Stimulator; Merc | 1969 |