chlorambucil has been researched along with Granuloma in 14 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Granuloma: A relatively small nodular inflammatory lesion containing grouped mononuclear phagocytes, caused by infectious and noninfectious agents.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report a case of necrobiotic xanthogranuloma that responded to treatment with chlorambucil." | 7.73 | Necrobiotic xanthogranuloma treated with chlorambucil. ( Fazel, N; Knuttle, R; Torabian, SZ, 2006) |
| "5 of 6 adults with generalized granuloma annulare responded favorably to therapy with low-dose chlorambucil." | 7.66 | Low-dose chlorambucil in the treatment of generalized granuloma annulare. ( Kossard, S; Winkelmann, RK, 1979) |
| "We report a case of necrobiotic xanthogranuloma that responded to treatment with chlorambucil." | 3.73 | Necrobiotic xanthogranuloma treated with chlorambucil. ( Fazel, N; Knuttle, R; Torabian, SZ, 2006) |
| "5 of 6 adults with generalized granuloma annulare responded favorably to therapy with low-dose chlorambucil." | 3.66 | Low-dose chlorambucil in the treatment of generalized granuloma annulare. ( Kossard, S; Winkelmann, RK, 1979) |
| "If the vasculitis is secondary to an underlying disease, such as lymphoma, therapy should be directed at the primary disease." | 2.37 | Pulmonary vasculitis. ( Fauci, AS; Leavitt, RY, 1986) |
| "Necrobiotic xanthogranuloma is a rare cutaneous condition that can be mistaken for atypical necrobiosis lipoidica." | 1.33 | Necrobiotic xanthogranuloma with paraproteinaemia. ( Andrews, V; Flann, S; Halpern, S; Wain, EM; Whittaker, S, 2006) |
| "At the same time, she developed xanthomatous patches on the face, neck, and shoulders (Fig." | 1.33 | Necrobiotic xanthogranuloma associated with paraproteinemia and non-Hodgkin's lymphoma developing into chronic lymphocytic leukemia: the first case reported in the literature and review of the literature. ( Oumeish, I; Oumeish, OY; Salman, T; Sharaiha, A; Tarawneh, M, 2006) |
| "Subsequently, standard chemotherapy for Hodgkin's disease induced complete clinical and biochemical remission." | 1.29 | Suspected malignant lymphoma presenting with widespread granulomatous lesions in bones and lymph nodes and responding to combination chemotherapy. ( Jensen, MK; Johansen, P; Pulczynski, S, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (71.43) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BERRY, CZ | 1 |
| SCHREIBER, MM | 1 |
| SHAPIRO, SI | 1 |
| Flann, S | 1 |
| Wain, EM | 1 |
| Halpern, S | 1 |
| Andrews, V | 1 |
| Whittaker, S | 1 |
| Oumeish, OY | 1 |
| Oumeish, I | 1 |
| Tarawneh, M | 1 |
| Salman, T | 1 |
| Sharaiha, A | 1 |
| Torabian, SZ | 1 |
| Fazel, N | 1 |
| Knuttle, R | 1 |
| Calas, E | 1 |
| Bonerandi, JJ | 1 |
| Migozzi, B | 1 |
| Breton, A | 1 |
| Bourdet, D | 1 |
| Follana, J | 1 |
| Mutasim, D | 1 |
| Karban, AK | 1 |
| Jensen, MK | 1 |
| Pulczynski, S | 1 |
| Johansen, P | 1 |
| Kossard, S | 2 |
| Winkelmann, RK | 2 |
| Rudolph, RI | 1 |
| Ginsburg, WW | 1 |
| O'Duffy, JD | 1 |
| Morris, JL | 1 |
| Huston, KA | 1 |
| Leavitt, RY | 1 |
| Fauci, AS | 1 |
| Marie, J | 1 |
| Hennequet, A | 1 |
| Lévêque, B | 1 |
| Debauchez, C | 1 |
| Desbois, C | 1 |
| Watchi, JM | 1 |
| Appalanarasayya, K | 1 |
| Devi, OB | 1 |
1 review available for chlorambucil and Granuloma
| Article | Year |
|---|---|
Pulmonary vasculitis.
Topics: Adrenal Cortex Hormones; Azathioprine; Behcet Syndrome; Chlorambucil; Connective Tissue Diseases; Cy | 1986 |
13 other studies available for chlorambucil and Granuloma
| Article | Year |
|---|---|
CUTANEOUS GRANULOMA WITH EOSINOPHILS.
Topics: Chlorambucil; Classification; Dermatology; Diagnosis, Differential; Eosinophilic Granuloma; Eosinoph | 1963 |
Necrobiotic xanthogranuloma with paraproteinaemia.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Chlorambucil; Cyclophosphamide; Female; | 2006 |
Necrobiotic xanthogranuloma associated with paraproteinemia and non-Hodgkin's lymphoma developing into chronic lymphocytic leukemia: the first case reported in the literature and review of the literature.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyc | 2006 |
Necrobiotic xanthogranuloma treated with chlorambucil.
Topics: Antineoplastic Agents, Alkylating; Chlorambucil; Dose-Response Relationship, Drug; Granuloma; Humans | 2006 |
[Perforating generalized granuloma annulare. A two case study (author's transl)].
Topics: Aged; Chlorambucil; Female; Granuloma; Heparin; Humans; Lipotropic Agents; Male; Skin Diseases | 1980 |
Granuloma annulare treated with chlorambucil: an 18-month follow-up.
Topics: Chlorambucil; Female; Granuloma; Humans; Middle Aged; Skin Diseases | 1983 |
Suspected malignant lymphoma presenting with widespread granulomatous lesions in bones and lymph nodes and responding to combination chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone and Bones; Chlorambucil; Diagnosis, Differentia | 1996 |
Low-dose chlorambucil in the treatment of generalized granuloma annulare.
Topics: Aged; Chlorambucil; Drug Evaluation; Female; Granuloma; Humans; Male; Middle Aged; Skin; Skin Diseas | 1979 |
Disseminated granuloma annulare treated with low-dose chlorambucil.
Topics: Chlorambucil; Female; Granuloma; Humans; Middle Aged; Skin Diseases | 1979 |
Response of generalized granuloma annulare to alkylating agents.
Topics: Aged; Alkylating Agents; Chlorambucil; Female; Granuloma; Humans; Male; Melphalan; Middle Aged; Pred | 1978 |
Multicentric reticulohistiocytosis: response to alkylating agents in six patients.
Topics: Adult; Aged; Alkylating Agents; Arthritis; Chlorambucil; Cyclophosphamide; Drug Therapy, Combination | 1989 |
[Histiocytic reticulosis in infants or Letterer-Siwe disease. (Clinical and therapeutical study)].
Topics: Acrodermatitis; Betamethasone; Biopsy; Blood Cell Count; Bone Diseases; Child, Preschool; Chlorambuc | 1968 |
Hand-Schueller-Christian disease. Report of a case and review of the literature.
Topics: Biopsy; Child, Preschool; Chlorambucil; Cyclophosphamide; Granuloma; Histiocytes; Histiocytosis, Lan | 1970 |