chlorambucil has been researched along with Granuloma, Lethal Midline in 2 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Granuloma, Lethal Midline: A condition that is characterized by inflammation, ulceration, and perforation of the nose and the PALATE with progressive destruction of midline facial structures. This syndrome can be manifested in several diseases including the nasal type of EXTRANODAL NK-T-CELL LYMPHOMA and GRANULOMATOSIS WITH POLYANGIITIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The classical type of Wegener's granulomatosis encompasses a necrotizing granulomatous vasculitis of the upper and lower respiratory tracts and a necrotizing glomerulonephritis." | 2.36 | [Wegener's granulomatosis and Wegener's Granuloma (author's transl)]. ( Chilla, R, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chilla, R | 1 |
| Chanda, JJ | 1 |
| Callen, JP | 1 |
1 review available for chlorambucil and Granuloma, Lethal Midline
| Article | Year |
|---|---|
[Wegener's granulomatosis and Wegener's Granuloma (author's transl)].
Topics: Chlorambucil; Cyclophosphamide; Glomerulonephritis; Glucocorticoids; Granuloma, Lethal Midline; Gran | 1980 |
1 other study available for chlorambucil and Granuloma, Lethal Midline
| Article | Year |
|---|---|
Necrotizing vasculitis (angiitis) with granulomatosis.
Topics: Azathioprine; Chlorambucil; Cyclophosphamide; Diagnosis, Differential; Granuloma, Lethal Midline; Gr | 1984 |