chlorambucil has been researched along with Genome Instability in 1 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mangerich, A | 1 |
| Debiak, M | 1 |
| Birtel, M | 1 |
| Ponath, V | 1 |
| Balszuweit, F | 1 |
| Lex, K | 1 |
| Martello, R | 1 |
| Burckhardt-Boer, W | 1 |
| Strobelt, R | 1 |
| Siegert, M | 1 |
| Thiermann, H | 1 |
| Steinritz, D | 1 |
| Schmidt, A | 1 |
| Bürkle, A | 1 |
1 other study available for chlorambucil and Genome Instability
| Article | Year |
|---|---|
Sulfur and nitrogen mustards induce characteristic poly(ADP-ribosyl)ation responses in HaCaT keratinocytes with distinctive cellular consequences.
Topics: Adenosine Diphosphate Ribose; Antidotes; Antineoplastic Agents, Alkylating; Cell Line; Cell Prolifer | 2016 |