chlorambucil has been researched along with Genital Neoplasms, Female in 5 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Genital Neoplasms, Female: Tumor or cancer of the female reproductive tract (GENITALIA, FEMALE).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty-nine patients with gynecological malignancies who had failed on conventional chemotherapeutic agents were treated with Leo 1031 to study the effective dosage and toxicity of the compound in gynecological malignancies." | 1.26 | Leo 1031 (NSC-134087) in gynecologic malignancies. ( Barlow, JJ; Lele, SB; Murphy, GP; Piver, MS, 1978) |
| "Generally, metastases responded better than the advanced primaries from which they were derived, except for those from breast tumours." | 1.25 | The influence of site of metastasis on tumour growth and response to chemotherapy. ( Bross, ID; Slack, NH, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| HRESCHCHYSHYN, MM | 1 |
| Lele, SB | 1 |
| Piver, MS | 1 |
| Barlow, JJ | 1 |
| Murphy, GP | 1 |
| Slack, NH | 1 |
| Bross, ID | 1 |
| Bloomfield, RD | 1 |
| Lewis, TL | 1 |
2 reviews available for chlorambucil and Genital Neoplasms, Female
| Article | Year |
|---|---|
Current cancer chemotherapy in obstetrics and gynecology.
Topics: Alkaloids; Alkylating Agents; Anti-Bacterial Agents; Antimetabolites; Blood Cell Count; Bone Marrow; | 1971 |
Trends in the treatment of pelvic malignant diseases.
Topics: Carcinoma; Chlorambucil; Cyclophosphamide; Female; Genital Neoplasms, Female; Humans; Hysterectomy; | 1971 |
3 other studies available for chlorambucil and Genital Neoplasms, Female
| Article | Year |
|---|---|
EXPERIENCES WITH CHEMOTHERAPY IN GYNECOLOGIC CANCER.
Topics: Antineoplastic Agents; Biomedical Research; Chlorambucil; Cyclophosphamide; Dactinomycin; Female; Ge | 1964 |
Leo 1031 (NSC-134087) in gynecologic malignancies.
Topics: Chlorambucil; Drug Therapy, Combination; Female; Genital Neoplasms, Female; Humans; Prednisolone | 1978 |
The influence of site of metastasis on tumour growth and response to chemotherapy.
Topics: Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Female; Fluorouracil; Genital Neoplasms, Fema | 1975 |