chlorambucil has been researched along with Experimental Hepatoma in 3 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wolf, M | 1 |
| Bauder-Wüst, U | 1 |
| Haberkorn, U | 1 |
| Mier, W | 1 |
| Eisenhut, M | 1 |
| Miyamoto, K | 1 |
| Wakabayashi, D | 1 |
| Minamino, T | 1 |
| Nomura, M | 1 |
| Egawa, H | 1 |
| Maki, A | 1 |
| Mori, K | 1 |
| Yamamoto, Y | 1 |
| Mitsuhashi, S | 1 |
| Bannai, K | 1 |
| Asano, K | 1 |
| Ozawa, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Efficacy, Safety, and Patient Reported Outcomes of Different Regimens of Transarterial Chemoembolization in Patients With Hepatocellular Carcinoma[NCT00493402] | Phase 3 | 365 participants (Actual) | Interventional | 2007-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for chlorambucil and Experimental Hepatoma
| Article | Year |
|---|---|
Alkylating benzamides with melanoma cytotoxicity: role of melanin, tyrosinase, intracellular pH and DNA interaction.
Topics: Animals; Antineoplastic Agents, Alkylating; Benzamides; Cell Survival; Chlorambucil; DNA; Drug Carri | 2005 |
Glutathione-S-transferase P-form dependent chlorambucil resistance in Yoshida rat ascites hepatoma cell lines.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cell Line; Chlor | 1994 |
Effects of intra-arterial chemotherapy with a new lipophilic anticancer agent, estradiol-chlorambucil (KM2210), dissolved in lipiodol on experimental liver tumor in rats.
Topics: Animals; Antineoplastic Agents; Carbon Radioisotopes; Chlorambucil; Dose-Response Relationship, Drug | 1990 |