chlorambucil has been researched along with Exanthem in 2 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "He developed recurrent skin rash, fever, hypereosinophilia, and acute renal failure after rechallenge with chlorambucil." | 5.35 | Drug rash with eosinophilia and systemic symptoms after chlorambucil treatment in chronic lymphocytic leukaemia. ( Damaj, G; Gruson, B; Makdassi, R; Roszkiewicz, F; Vaida, I, 2009) |
| " The aim of the present study was to evaluate the safety, efficacy and pharmacokinetics of ofatumumab in combination with chlorambucil in Japanese patients with previously untreated CLL who were inappropriate for fludarabine-based therapy." | 2.84 | Ofatumumab combined with chlorambucil for previously untreated chronic lymphocytic leukemia: a phase I/II, open-label study in Japan. ( Ando, K; Fujita, T; Hatake, K; Ogura, M; Takada, K; Taniwaki, M; Zhang, F, 2017) |
| "He developed recurrent skin rash, fever, hypereosinophilia, and acute renal failure after rechallenge with chlorambucil." | 1.35 | Drug rash with eosinophilia and systemic symptoms after chlorambucil treatment in chronic lymphocytic leukaemia. ( Damaj, G; Gruson, B; Makdassi, R; Roszkiewicz, F; Vaida, I, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hatake, K | 1 |
| Ogura, M | 1 |
| Takada, K | 1 |
| Taniwaki, M | 1 |
| Zhang, F | 1 |
| Fujita, T | 1 |
| Ando, K | 1 |
| Vaida, I | 1 |
| Roszkiewicz, F | 1 |
| Gruson, B | 1 |
| Makdassi, R | 1 |
| Damaj, G | 1 |
1 trial available for chlorambucil and Exanthem
| Article | Year |
|---|---|
Ofatumumab combined with chlorambucil for previously untreated chronic lymphocytic leukemia: a phase I/II, open-label study in Japan.
Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic C | 2017 |
1 other study available for chlorambucil and Exanthem
| Article | Year |
|---|---|
Drug rash with eosinophilia and systemic symptoms after chlorambucil treatment in chronic lymphocytic leukaemia.
Topics: Acute Kidney Injury; Adrenal Cortex Hormones; Aged; Chlorambucil; Drug Eruptions; Eosinophilia; Exan | 2009 |