chlorambucil has been researched along with EHS Tumor in 13 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "For melphalan, neither pretreatment agent produced any change in tumor response." | 1.26 | Effect of misonidazole or metronidazole pretreatment on the response of the RIF-1 mouse sarcoma to melphalan, cyclophosphamide, chlorambucil and CCNU. ( Twentyman, P; Workman, P, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (92.31) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| ARROYONOMBELA, JJ | 1 |
| RODRIGUEZMURCIA, C | 1 |
| NAVASHIN, SM | 1 |
| FOMINA, IP | 1 |
| TERENTEVA, TG | 1 |
| Twentyman, PR | 1 |
| Twentyman, P | 1 |
| Workman, P | 2 |
| Godenèche, D | 1 |
| Madelmont, JC | 1 |
| Moreau, MF | 1 |
| Plagne, R | 1 |
| Meyniel, G | 1 |
| Jin, GZ | 1 |
| You, YJ | 1 |
| Kim, Y | 1 |
| Nam, NH | 1 |
| Ahn, BZ | 1 |
| Lee, FY | 1 |
| Coe, P | 1 |
| Klener, P | 1 |
| Kravchenko, AI | 4 |
| Chernov, VA | 1 |
| Korobova, IuN | 2 |
| Karaivanova, MKh | 1 |
1 trial available for chlorambucil and EHS Tumor
| Article | Year |
|---|---|
Vinca alkaloids. Experimental and clinical trials.
Topics: Animals; Cell Movement; Chlorambucil; Choriocarcinoma; Female; Hematopoiesis; Hematopoietic Stem Cel | 1974 |
12 other studies available for chlorambucil and EHS Tumor
| Article | Year |
|---|---|
[CYTOSTATICS OF VEGETABLE ORIGIN AND OF SYNTHETIC ORIGIN].
Topics: Animals; Antineoplastic Agents; Biological Assay; Carcinoma, Ehrlich Tumor; Chlorambucil; Cytostatic | 1963 |
[STUDIES ON THE ANTINEOPLASTIC EFFECT OF CHLORBUTINPENICILLIN].
Topics: Animals; Antineoplastic Agents; Chlorambucil; Neoplasms; Penicillins; Pharmacology; Rats; Research; | 1964 |
Modification by WR 2721 of the response to chemotherapy of tumours and normal tissues in the mouse.
Topics: Amifostine; Animals; Antineoplastic Agents; Chlorambucil; Cisplatin; Cyclophosphamide; Female; Leuko | 1983 |
Effect of misonidazole or metronidazole pretreatment on the response of the RIF-1 mouse sarcoma to melphalan, cyclophosphamide, chlorambucil and CCNU.
Topics: Animals; Antineoplastic Agents; Cell Survival; Chlorambucil; Cyclophosphamide; Drug Synergism; Drug | 1982 |
Comparative physico-chemical properties, biological effects, and disposition in mice of four nitrogen mustards.
Topics: 1-Naphthylamine; Alkylation; Animals; Chemical Phenomena; Chemistry; Chlorambucil; DNA, Neoplasm; Hy | 1980 |
Esters of chlorambucil with 2-substituted 1,4-dihydroxy-9,10-anthraquinones as multifunctional anticancer agents.
Topics: Animals; Anthraquinones; Antineoplastic Agents; Chlorambucil; Drug Screening Assays, Antitumor; Leuk | 2001 |
Pharmacokinetic basis for the comparative antitumour activity and toxicity of chlorambucil, phenylacetic acid mustard and beta, beta-difluorochlorambucil (CB 7103) in mice.
Topics: Animals; Antineoplastic Agents; Blood Proteins; Chlorambucil; Chromatography, High Pressure Liquid; | 1986 |
[The effect of chlorbutin with cortisone on sarcoma 45 growth in gonadectomized rats].
Topics: Animals; Castration; Chlorambucil; Cortisone; Drug Combinations; Male; Rats; Sarcoma, Experimental | 1973 |
[The effect of DOCA and adrenaline on the antineoplastic activity of chlorbutin].
Topics: Adrenalectomy; Animals; Chlorambucil; Desoxycorticosterone; Drug Synergism; Epinephrine; Male; Rats; | 1971 |
[The dimension in the adrenal glands cell nuclei of the rat following administration of chlorbutin, cortisone, adrenaline and their combinations].
Topics: Adrenal Glands; Adrenal Insufficiency; Animals; Cell Nucleus; Chlorambucil; Cortisone; Epinephrine; | 1971 |
[A method of primary selection of antitumor agents].
Topics: Adenocarcinoma; Animals; Carcinoma 256, Walker; Chlorambucil; Cyclophosphamide; Melphalan; Mercaptop | 1971 |
[Dimensions of adrenal gland cell nuclei in rats with sarcoma 45].
Topics: Adrenal Gland Neoplasms; Animals; Cell Nucleus; Chlorambucil; Karyometry; Male; Mathematics; Neoplas | 1967 |