chlorambucil has been researched along with Dysgerminoma in 47 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Dysgerminoma: A malignant ovarian neoplasm, thought to be derived from primordial germ cells of the sexually undifferentiated embryonic gonad. It is the counterpart of the classical seminoma of the testis, to which it is both grossly and histologically identical. Dysgerminomas comprise 16% of all germ cell tumors but are rare before the age of 10, although nearly 50% occur before the age of 20. They are generally considered of low-grade malignancy but may spread if the tumor extends through its capsule and involves lymph nodes or blood vessels. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1646)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with germ cell tumors may be divided into "good risk" (high likelihood of complete response) and "poor risk" (low likelihood of complete response) based on pretreatment serum tumor markers, extent of disease, histology, and primary site." | 2.37 | Chemotherapy for germ cell tumors. ( Bosl, GJ; Motzer, RJ, 1987) |
| "Bilateral testicular tumors were detected on palpation and ultrasonography." | 2.37 | [A case of bilateral testicular tumors showing remarkable regression of huge metastatic tumors after VAB-6 combined chemotherapy]. ( Hisazumi, H; Nakajima, K; Nakashima, T; Nitta, M; Sugata, T; Tokunaga, S; Yokoyama, O, 1988) |
| "Disseminated germ cell testicular cancer proved to be highly sensitive to platinum-containing chemotherapy regimens." | 1.27 | Vinblastine, actinomycin D, bleomycin, cyclophosphamide and cis-platinum for advanced germ cell testis tumors: Brazilian experience. ( de Góes, GM; Simon, SD; Srougi, M, 1985) |
| "Sixteen patients with metastatic testicular cancer were treated with combination chemotherapy including cisplatin (CDDP) at 3- to 4-week intervals for two to five courses." | 1.27 | [Hypomagnesemia following chemotherapy of disseminated testicular tumors]. ( Hida, S; Nishimura, K; Nishio, Y; Okada, K; Okada, Y; Yoshida, O, 1988) |
| "Dysgerminomas are highly sensitive not only to irradiation but also to chemotherapy." | 1.27 | [Chemotherapy of dysgerminoma]. ( Brökelmann, J; Hartlapp, JH, 1987) |
| "Of 250 testicular tumors treated up to May 1975 233 (93." | 1.26 | The combined surgical and chemotherapeutic approach to non-seminomatous cancer of the testicle. ( Vahlensieck, W; Weissbach, L, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 45 (95.74) | 18.7374 |
| 1990's | 2 (4.26) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MIALE, A | 1 |
| KESLER, K | 1 |
| LEBHERZ, TB | 1 |
| HUSTON, JW | 1 |
| AUSTIN, JA | 1 |
| BOYCE, CR | 1 |
| Mackenzie, AR | 2 |
| Laplante, MP | 1 |
| Mount, BM | 1 |
| Ekman, P | 1 |
| Vugrin, D | 3 |
| Whitmore, WF | 5 |
| Golbey, RB | 5 |
| Williams, SD | 1 |
| Loehrer, PJ | 1 |
| Einhorn, LH | 1 |
| Merrin, C | 1 |
| Vahlensieck, W | 3 |
| Weissbach, L | 3 |
| Kamat, MR | 1 |
| Kulkarni, JN | 1 |
| Tongaonkar, HB | 1 |
| Ravi, R | 1 |
| Tiuliandin, SA | 1 |
| Srougi, M | 1 |
| Simon, SD | 1 |
| de Góes, GM | 1 |
| Israel, A | 1 |
| Bosl, GJ | 4 |
| Whitmore, W | 1 |
| Martini, N | 1 |
| Hida, S | 2 |
| Kawakita, M | 1 |
| Takenawa, J | 1 |
| Fukuzawa, S | 1 |
| Okuno, H | 1 |
| Yamauchi, T | 1 |
| Oishi, K | 1 |
| Nishio, Y | 2 |
| Takeuchi, H | 1 |
| Okada, K | 2 |
| Motzer, RJ | 2 |
| Herr, HW | 1 |
| Bosl, G | 1 |
| Carter, GE | 1 |
| Lieskovsky, G | 1 |
| Skinner, DG | 2 |
| Daniels, JR | 1 |
| Geller, NL | 1 |
| Penenberg, D | 1 |
| Yagoda, A | 1 |
| Golbey, R | 1 |
| Fair, WR | 1 |
| Sogani, P | 2 |
| Herr, H | 2 |
| Nishimura, K | 1 |
| Okada, Y | 1 |
| Yoshida, O | 1 |
| Masuda, F | 1 |
| Nakada, J | 1 |
| Kondo, N | 1 |
| Takahashi, T | 1 |
| Mochizuki, A | 1 |
| Iizuka, N | 1 |
| Nakashima, T | 1 |
| Nakajima, K | 1 |
| Yokoyama, O | 1 |
| Sugata, T | 1 |
| Tokunaga, S | 1 |
| Nitta, M | 1 |
| Hisazumi, H | 1 |
| Stanton, GF | 1 |
| Morse, M | 1 |
| Le Duc, A | 1 |
| Gisselbrecht, C | 1 |
| Le Doze, H | 1 |
| Mignot, L | 1 |
| Brökelmann, J | 1 |
| Hartlapp, JH | 1 |
| Gödde, S | 1 |
| Gibson, GR | 1 |
| Wilms, K | 3 |
| Bonadonna, G | 1 |
| Baumgartner, G | 1 |
| Rathert, P | 1 |
| Terhorst, B | 1 |
| Lutzeyer, W | 1 |
| Lange, CE | 1 |
| Meyhöfer, W | 1 |
| Astrakhan, VI | 1 |
| Monul, FA | 1 |
| Woodruff, JD | 1 |
| Protos, P | 1 |
| Peterson, WF | 1 |
| Ryssel, HJ | 1 |
| Sonntag, RW | 1 |
| Brunner, KW | 1 |
| Du Priest, RW | 1 |
| Fletcher, WS | 1 |
| Dargent, M | 1 |
| Pommatau, E | 1 |
| Brunat, M | 1 |
| Furnari, S | 1 |
| Pavone-Macaluso, M | 1 |
| Veroux, G | 1 |
| Mattea, E | 1 |
| Hartwich, G | 1 |
| Butzler, W | 1 |
| Leadbetter, WF | 1 |
| Wider, JA | 1 |
| Marshall, JR | 1 |
| Bardin, CW | 1 |
| Lipsett, MB | 1 |
| Ross, GT | 1 |
5 reviews available for chlorambucil and Dysgerminoma
| Article | Year |
|---|---|
Current concepts in the management of testicular germ cell tumours in adults. A review.
Topics: Adult; alpha-Fetoproteins; Bleomycin; Chlorambucil; Chorionic Gonadotropin; Chorionic Gonadotropin, | 1982 |
Seminoma.
Topics: Adult; Aging; Castration; Chlorambucil; Cryptorchidism; Cyclophosphamide; Dysgerminoma; Humans; Male | 1977 |
Chemotherapy for germ cell tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Combined Modalit | 1987 |
[A case of bilateral testicular tumors showing remarkable regression of huge metastatic tumors after VAB-6 combined chemotherapy].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Combined | 1988 |
Chemotherapy of testicular tumors.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Chlorambucil; Dactinomycin; Dysgermin | 1971 |
42 other studies available for chlorambucil and Dysgerminoma
| Article | Year |
|---|---|
OVARIAN DISGERMINOMA. REPORT OF A CASE TREATED WITH ACTINOMYCIN D, CHLORAMBUCIL, AND METHOTREXATE AFTER MASSIVE IRRADIATION.
Topics: Chlorambucil; Dactinomycin; Drug Therapy; Dysgerminoma; Female; Humans; Methotrexate; Neoplasms; Neo | 1964 |
SUSTAINED PALLIATION IN OVARIAN CARCINOMA.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Ascites; Carcinoma; Chlorambucil; Dysgerminoma; Female; Gr | 1965 |
Chemotherapy of metastatic testis cancer. Results in 154 patients.
Topics: Adult; Antibiotics, Antineoplastic; Antimetabolites; Chlorambucil; Choriocarcinoma; Dactinomycin; Dy | 1966 |
Lymphadenectomy for testicular carcinoma.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Chor | 1982 |
VAB-6 combination chemotherapy without maintenance in treatment of disseminated cancer of the testis.
Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; | 1983 |
Vinblastine, actinomycin D, bleomycin, cyclophosphamide and cis-platinum combination chemotherapy in metastatic testis cancer--a 1-year program.
Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; | 1982 |
The VAB-6 regimen in the treatment of metastatic seminoma.
Topics: Abdominal Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cispla | 1984 |
Chemotherapy of advanced testicular cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Combined Modalit | 1984 |
The combined surgical and chemotherapeutic approach to non-seminomatous cancer of the testicle.
Topics: Chlorambucil; Dactinomycin; Drug Therapy, Combination; Dysgerminoma; Humans; Ifosfamide; Lymph Node | 1977 |
Value of retroperitoneal lymph node dissection in advanced testicular seminoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Combined Modalit | 1992 |
[Infusion of high doses of platidiam in the treatment of patients with germ cell testicular tumors].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Cyclophosphamide | 1990 |
Vinblastine, actinomycin D, bleomycin, cyclophosphamide and cis-platinum for advanced germ cell testis tumors: Brazilian experience.
Topics: Adult; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brazil; Chlorambucil; Ci | 1985 |
The results of chemotherapy for extragonadal germ-cell tumors in the cisplatin era: the Memorial Sloan-Kettering Cancer Center experience (1975 to 1982).
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplati | 1985 |
[VAB-6 combination chemotherapy in patients with stage II, III testicular tumor].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplati | 1986 |
Residual mass after chemotherapy for seminoma: changing concepts of management.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Combined Modalit | 1987 |
Reassessment of the role of adjunctive surgical therapy in the treatment of advanced germ cell tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Combined Modalit | 1987 |
Advanced seminoma: the role of chemotherapy and adjunctive surgery.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Combined Modalit | 1988 |
[Hypomagnesemia following chemotherapy of disseminated testicular tumors].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Choriocarcinoma; Cis | 1988 |
[Treatment of nonseminomatous testicular tumor with liver metastases].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Choriocarcinoma; Cis | 1988 |
VAB-6 as initial treatment of patients with advanced seminoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Cyclophos | 1985 |
[Role of chemotherapy in the treatment of cancer of the testis in adults].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Choriocarcinoma; Cis | 1985 |
[Chemotherapy of dysgerminoma].
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined | 1987 |
[Transperitoneal lymph node excision and cytostatic postoperative treatment of malignant germinal testicular neoplasms].
Topics: Antineoplastic Agents; Chlorambucil; Dactinomycin; Drug Synergism; Dysgerminoma; Humans; Lymph Node | 1968 |
Lymphangiography as a diagnostic aid. Report of a case.
Topics: Abdomen; Chlorambucil; Dactinomycin; Dysgerminoma; Humans; Hydronephrosis; Lymph Nodes; Lymphography | 1964 |
[Cytostatic treatment of malignant testicular neoplasms].
Topics: Adult; Antibiotics, Antineoplastic; Chlorambucil; Choriocarcinoma; Cyclophosphamide; Dactinomycin; D | 1971 |
[Cytostatic therapy of malignant testicular neoplasms].
Topics: Antineoplastic Agents; Castration; Chlorambucil; Dactinomycin; Dysgerminoma; Humans; Male; Methotrex | 1972 |
[Cytostatic therapy of malignant testicular tumors].
Topics: Antineoplastic Agents; Chlorambucil; Dactinomycin; Dysgerminoma; Humans; Male; Methotrexate; Plicamy | 1973 |
[Results with the cytostatic agent bleomycin in tumour therapy (author's transl)].
Topics: Adult; Aged; Bleomycin; Bronchial Neoplasms; Carcinoma, Squamous Cell; Chlorambucil; Doxorubicin; Dr | 1973 |
[Bleomycin for malignant tumours of the genitals of the male (author's transl)].
Topics: Adrenal Cortex Hormones; Adult; Age Factors; Aged; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil | 1974 |
[Testicular histology, ejaculate and nucleoprotein content of spermatozoa in patients with treated testicular tumors].
Topics: Adult; Biopsy; Chlorambucil; Dactinomycin; DNA; Dysgerminoma; Ejaculation; Fertility; Humans; Male; | 1974 |
[The combined chemotherapy of testicular tumors resistant to sarcolysin].
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Chlorambucil; Choriocarcinoma; Cyclophosphamide; | 1967 |
Ovarian teratomas. Relationship of histologic and ontogenic factors to prognosis.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Chlorambucil; Choriocarcinoma; Dactinomycin | 1968 |
[Treatment of choriocarcinoma and malignant testicular neoplasms in internal medicine].
Topics: Chlorambucil; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Dysgerminoma; Humans; Lung Neoplasms; | 1967 |
Chemotherapy of testicular germinal tumors.
Topics: Alkylating Agents; Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Dactinomycin; Dysgerminoma | 1973 |
[Apropos of an experience with the polychemotherapy of cancer].
Topics: Adult; Bone Neoplasms; Child; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug Synergism; Dysgermi | 1968 |
Cancer chemotherapy in urology.
Topics: Adenocarcinoma; Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites; Chlorambucil; Cobal | 1971 |
Operative and cytostatic treatment of germinal tumours of the testis.
Topics: Adolescent; Adult; Antineoplastic Agents; Castration; Child; Child, Preschool; Chlorambucil; Cyclic | 1973 |
[Secondary tumors in hemoblastoses during cytostatic treatment].
Topics: Adrenal Gland Neoplasms; Aged; Antineoplastic Agents; Bronchial Neoplasms; Busulfan; Carcinoma; Chlo | 1971 |
The surgical management of testis tumors.
Topics: Adolescent; Adult; Castration; Child; Child, Preschool; Chlorambucil; Choriocarcinoma; Dactinomycin; | 1971 |
The place of chemotherapy in the treatment of testicular tumors.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Chlorambucil; Choriocarcinoma; Chorionic Gonadot | 1970 |
Sustained remissions after chemotherapy for primary ovarian cancers containing choriocarcinoma.
Topics: Adolescent; Adult; Child; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; Dysge | 1969 |
The chemotherapy of metastatic seminoma.
Topics: Chlorambucil; Dysgerminoma; Humans; Male; Middle Aged; Testicular Neoplasms | 1966 |