chlorambucil has been researched along with Duncan Disease in 4 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with chlorambucil produced complete reversal of hepatosplenomegaly, anemia, neutropenia and lymphocytosis, and reduction of marrow infiltration." | 5.27 | Lymphoproliferative disorder of large granular lymphocytes: reversal of lymphocyte proliferation, anemia and neutropenia with chlorambucil. ( Cazzola, M; Ippoliti, G; Meloni, F; Pedrazzoli, P; Stella, CC, 1987) |
| "Treatment with chlorambucil produced complete reversal of hepatosplenomegaly, anemia, neutropenia and lymphocytosis, and reduction of marrow infiltration." | 1.27 | Lymphoproliferative disorder of large granular lymphocytes: reversal of lymphocyte proliferation, anemia and neutropenia with chlorambucil. ( Cazzola, M; Ippoliti, G; Meloni, F; Pedrazzoli, P; Stella, CC, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dousset, B | 1 |
| Boudet, MJ | 1 |
| Soubrane, O | 1 |
| Calmus, Y | 1 |
| Bernard, O | 1 |
| Houssin, D | 1 |
| Kuenn, JW | 1 |
| Weber, R | 1 |
| Teague, PO | 1 |
| Keitt, AS | 1 |
| Jacobs, P | 1 |
| King, HS | 1 |
| Pedrazzoli, P | 1 |
| Cazzola, M | 1 |
| Stella, CC | 1 |
| Ippoliti, G | 1 |
| Meloni, F | 1 |
1 trial available for chlorambucil and Duncan Disease
| Article | Year |
|---|---|
A randomized prospective comparison of chemotherapy to total body irradiation as initial treatment for the indolent lymphoproliferative diseases.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Clinic | 1987 |
3 other studies available for chlorambucil and Duncan Disease
| Article | Year |
|---|---|
Liver transplantation in patients with preexisting malignancy.
Topics: Adenocarcinoma; Adolescent; Adult; Carcinoma, Renal Cell; Child; Child, Preschool; Chlorambucil; Col | 1995 |
Cryopathic gangrene with an IgM lambda cryoprecipitating cold agglutinin.
Topics: Adult; Agglutinins; Autoantibodies; Breast Neoplasms; Chlorambucil; Cryoglobulins; Female; Gangrene; | 1978 |
Lymphoproliferative disorder of large granular lymphocytes: reversal of lymphocyte proliferation, anemia and neutropenia with chlorambucil.
Topics: Anemia; Bone Marrow; Cell Division; Chlorambucil; Danazol; Drug Therapy, Combination; Female; Humans | 1987 |