chlorambucil has been researched along with Diffuse Parenchymal Lung Disease in 4 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chlorambucil is a rare cause of pulmonary disease." | 2.38 | Interstitial lung disease--an underdiagnosed side effect of chlorambucil? ( Huhn, D; Kingreen, D; Mohr, M; Rühl, H, 1993) |
| "We describe two cases of interstitial lung disease in patients with non-Hodgkin's lymphoma who were treated with combination chemotherapy including mitozantrone." | 1.30 | Interstitial pneumonitis following mitozantrone, chlorambucil and prednisolone (MCP) chemotherapy. ( Johnson, S; Nicholson, AG; Rule, S; Stone, R; Tighe, M; Tomlinson, J, 1999) |
| "A patient developed an interstitial pneumonitis while receiving chlorambucil for a chronic lymphocytic leukemia (cumulative dose, 8,340 mg)." | 1.29 | Chlorambucil-associated pneumonitis. ( Clauvel, JP; Couderc, LJ; Crestani, B; Frija, J; Israël-Biet, D; Jaccard, A, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McCune, WJ | 1 |
| Vallance, DK | 1 |
| Lynch, JP | 1 |
| Mohr, M | 1 |
| Kingreen, D | 1 |
| Rühl, H | 1 |
| Huhn, D | 1 |
| Crestani, B | 1 |
| Jaccard, A | 1 |
| Israël-Biet, D | 1 |
| Couderc, LJ | 1 |
| Frija, J | 1 |
| Clauvel, JP | 1 |
| Tomlinson, J | 1 |
| Tighe, M | 1 |
| Johnson, S | 1 |
| Stone, R | 1 |
| Nicholson, AG | 1 |
| Rule, S | 1 |
2 reviews available for chlorambucil and Diffuse Parenchymal Lung Disease
| Article | Year |
|---|---|
Immunosuppressive drug therapy.
Topics: Adrenal Cortex Hormones; Azathioprine; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Cyc | 1994 |
Interstitial lung disease--an underdiagnosed side effect of chlorambucil?
Topics: Chlorambucil; Humans; Interferon Type I; Leukemia, Lymphocytic, Chronic, B-Cell; Lung Diseases, Inte | 1993 |
2 other studies available for chlorambucil and Diffuse Parenchymal Lung Disease
| Article | Year |
|---|---|
Chlorambucil-associated pneumonitis.
Topics: Alveolitis, Extrinsic Allergic; Bronchoalveolar Lavage Fluid; Chlorambucil; Humans; Leukemia, Lympho | 1994 |
Interstitial pneumonitis following mitozantrone, chlorambucil and prednisolone (MCP) chemotherapy.
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Female; H | 1999 |