chlorambucil has been researched along with Diffuse Mixed Small and Large Cell Lymphoma in 153 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Anecdotal reports of chlorambucil-induced seizures have sporadically appeared, mainly in the nononcologic literature." | 8.79 | Chlorambucil-induced seizures. ( Cooper, DL; Khan, KK; Salloum, E, 1997) |
| "We investigated the toxicity and efficacy of the chimaeric anti-CD20 antibody rituximab in combination with standard-dose chlorambucil in newly diagnosed and relapsed/refractory indolent B-cell lymphoma patients." | 5.10 | Chlorambucil in combination with induction and maintenance rituximab is feasible and active in indolent non-Hodgkin's lymphoma. ( Bertolini, F; Calleri, A; Cavalli, F; Laszlo, D; Mancuso, P; Martinelli, G; Pastano, R; Santoro, P; Vanazzi, A; Zucca, E, 2003) |
| "Anecdotal reports of chlorambucil-induced seizures have sporadically appeared, mainly in the nononcologic literature." | 4.79 | Chlorambucil-induced seizures. ( Cooper, DL; Khan, KK; Salloum, E, 1997) |
| " The mean bioavailability was 14% for chlorambucil, 21% for phenylacetic acid mustard, and 22% for prednisolone, when given as prednimustine, compared to the administration of free compounds in stoichiometrically equivalent doses." | 2.67 | Comparative pharmacokinetics of chlorambucil and prednimustine after oral administration. ( Loos, U; Malek, M; Musch, E; Riedel, E, 1991) |
| "In the chronic lymphocytic leukemia group, 3/4 have had benefit." | 2.64 | Treatment of chronic lymphocytic leukemia and lymphosarcoma with a new chlorambucil ester of prednisolone (Leo 1031) (NSC-134087). ( Aungst, CW; Mittelman, A; Murphy, GP, 1975) |
| "Histopathological subtypes consist of Burkitt's lymphoma (BL) in 32 (43." | 1.48 | Demographics and Outome in Paediatric Non-Hodgkin Lymphoma: Single Centre Experience at The Children Hospital Lahore, Pakistan. ( Anwar, S; Faizan, M; Khan, S, 2018) |
| "Patients with intestinal small cell lymphosarcoma can present identical clinical signs, and differentiating between these two conditions can be a challenge." | 1.39 | Feline small cell lymphosarcoma versus inflammatory bowel disease: treatment and prognosis. ( Al-Ghazlat, S; de Rezende, CE, 2013) |
| "At the same time, she developed xanthomatous patches on the face, neck, and shoulders (Fig." | 1.33 | Necrobiotic xanthogranuloma associated with paraproteinemia and non-Hodgkin's lymphoma developing into chronic lymphocytic leukemia: the first case reported in the literature and review of the literature. ( Oumeish, I; Oumeish, OY; Salman, T; Sharaiha, A; Tarawneh, M, 2006) |
| " Pharmacokinetic studies suggest decreased bioavailability with successive cycles, probably due to accelerated metabolism." | 1.32 | High dose chlorambucil in the treatment of lymphoid malignancies. ( Nicolle, A; Proctor, SJ; Summerfield, GP, 2004) |
| "Chlorambucil has been used for many years for the treatment of low-grade B-cell lymphoproliferative disorders, including chronic lymphocytic leukaemia and low-grade non-Hodgkin's lymphoma." | 1.31 | High-dose chlorambucil for the treatment of chronic lymphocytic leukaemia and low-grade non-Hodgkin's lymphoma. ( Mounter, PJ; Proctor, SJ; Summerfield, GP; Taylor, PR, 2002) |
| " The dosage of chlorambucil was decreased with a subsequent decrease in symptomatology." | 1.30 | Myoclonus due to chlorambucil in two adults with lymphoma. ( Bayliff, CD; Kovacs, MJ; Wyllie, AR, 1997) |
| "We describe two cases of interstitial lung disease in patients with non-Hodgkin's lymphoma who were treated with combination chemotherapy including mitozantrone." | 1.30 | Interstitial pneumonitis following mitozantrone, chlorambucil and prednisolone (MCP) chemotherapy. ( Johnson, S; Nicholson, AG; Rule, S; Stone, R; Tighe, M; Tomlinson, J, 1999) |
| "One response, however, did relate that diffuse histiocytic lymphoma developed in three of 141 patients receiving prolonged chlorambucil therapy for polycythemia vera." | 1.26 | Lymphoma in primary chronic cold hemagglutinin disease treated with chlorambucil. ( Chaplin, H, 1982) |
| "Low-grade malignant lymphomas are treated best with conventional doses of an alkylating agent." | 1.26 | [Chemotherapy in non-Hodgkin's lymphomas (author's transl)]. ( Schmidt, CG, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 88 (57.52) | 18.7374 |
| 1990's | 37 (24.18) | 18.2507 |
| 2000's | 25 (16.34) | 29.6817 |
| 2010's | 3 (1.96) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Faizan, M | 1 |
| Anwar, S | 1 |
| Khan, S | 1 |
| de Rezende, CE | 1 |
| Al-Ghazlat, S | 1 |
| Martinelli, G | 3 |
| Montoro, J | 1 |
| Vanazzi, A | 2 |
| Andreola, G | 2 |
| Liptrott, S | 1 |
| Radice, D | 1 |
| Negri, M | 1 |
| Preda, L | 1 |
| Pruneri, G | 1 |
| Laszlo, D | 3 |
| Jonathan, F | 1 |
| Leleu, X | 1 |
| Soumerai, J | 1 |
| Roccaro, A | 1 |
| Hatjiharissi, E | 1 |
| Hunter, ZR | 1 |
| Manning, R | 1 |
| Ciccarelli, BT | 1 |
| Sacco, A | 1 |
| Ioakimidis, L | 1 |
| Adamia, S | 1 |
| Moreau, AS | 1 |
| Patterson, CJ | 1 |
| Ghobrial, IM | 1 |
| Treon, SP | 1 |
| Schmitt, B | 1 |
| Wendtner, CM | 1 |
| Bergmann, M | 1 |
| Busch, R | 1 |
| Franke, A | 2 |
| Pasold, R | 2 |
| Schlag, R | 1 |
| Hopfinger, G | 1 |
| Hiddemann, W | 1 |
| Emmerich, B | 1 |
| Hallek, M | 1 |
| Davies, JH | 1 |
| Whitaker, SJ | 1 |
| Herold, M | 1 |
| Dölken, G | 1 |
| Fiedler, F | 1 |
| Freund, M | 1 |
| Helbig, W | 1 |
| Ardeshna, KM | 1 |
| Smith, P | 1 |
| Norton, A | 1 |
| Hancock, BW | 1 |
| Hoskin, PJ | 1 |
| MacLennan, KA | 1 |
| Marcus, RE | 1 |
| Jelliffe, A | 1 |
| Vaughan, G | 1 |
| Linch, DC | 1 |
| PITNEY, WR | 1 |
| MOLANDER, DW | 1 |
| WERDEGAR, D | 1 |
| ADLER, H | 1 |
| WATLINGTON, C | 1 |
| WILLIAMS, HM | 1 |
| FEIWEL, M | 1 |
| MUNRO, DD | 1 |
| VIGI, F | 1 |
| BURNINGHAM, RA | 1 |
| RESTREPO, A | 1 |
| PUGH, RP | 1 |
| BROWN, EB | 1 |
| SCHLOSSMAN, SF | 1 |
| KHURI, PD | 1 |
| LESSNER, HE | 1 |
| HARRINGTON, WJ | 1 |
| DIAMANDOPOULOS, GT | 1 |
| SMITH, EB | 1 |
| IRVINE, RA | 1 |
| ROBERTSON, WB | 1 |
| TANIDA, T | 1 |
| PAPAC, RJ | 1 |
| WOOD, DA | 2 |
| BROUET, G | 1 |
| MARCHE, J | 1 |
| CHRETIEN, J | 1 |
| HUGUS, FC | 1 |
| KARNOFSKY, DA | 1 |
| SANDBERG, AA | 1 |
| ISHIHARA, T | 1 |
| KIKUCHI, Y | 1 |
| CROSSWHITE, LH | 1 |
| HUTCHISON, JL | 1 |
| EZDINLI, EZ | 3 |
| STUTZMAN, L | 3 |
| WANEBO, HJ | 1 |
| CLARKSON, BD | 1 |
| PRADHAN, SN | 1 |
| WEST, WL | 1 |
| RABENKO, J | 1 |
| Bertolini, F | 2 |
| Pastano, R | 1 |
| Mancuso, P | 2 |
| Calleri, A | 1 |
| Santoro, P | 1 |
| Cavalli, F | 3 |
| Zucca, E | 3 |
| Seriakov, AP | 1 |
| Ushakov, II | 1 |
| Ardashev, VN | 1 |
| Mazurov, VI | 1 |
| Korotkiĭ, AN | 1 |
| Froehner, M | 1 |
| Haase, M | 1 |
| Hakenberg, OW | 1 |
| Wirth, MP | 1 |
| Nicolle, A | 1 |
| Proctor, SJ | 7 |
| Summerfield, GP | 3 |
| Wöhrer, S | 1 |
| Raderer, M | 1 |
| Kaufmann, H | 1 |
| Hejna, M | 1 |
| Chott, A | 1 |
| Zielinski, CC | 1 |
| Drach, J | 1 |
| Goor, KM | 1 |
| Schaafsma, MR | 1 |
| Huijgens, PC | 1 |
| van Agthoven, M | 1 |
| Willis, CR | 1 |
| Goodrich, A | 1 |
| Park, K | 1 |
| Waselenko, JK | 1 |
| Lucas, M | 1 |
| Reese, A | 1 |
| Diehl, LF | 1 |
| Grever, MR | 1 |
| Byrd, JC | 1 |
| Flinn, IW | 1 |
| Oumeish, OY | 1 |
| Oumeish, I | 1 |
| Tarawneh, M | 1 |
| Salman, T | 1 |
| Sharaiha, A | 1 |
| Bassi, S | 1 |
| Agazzi, A | 1 |
| Antoniotti, P | 1 |
| Balzano, R | 1 |
| Lau, CP | 1 |
| Ma, B | 1 |
| Chan, AT | 1 |
| Taylor, PR | 5 |
| White, JM | 2 |
| Prescott, RJ | 3 |
| Angus, B | 4 |
| Galloway, MJ | 3 |
| Jackson, GH | 3 |
| Lessells, AM | 2 |
| Lucraft, HH | 4 |
| Rigacci, L | 1 |
| Nassi, L | 1 |
| Puccioni, M | 1 |
| Mappa, S | 1 |
| Polito, E | 1 |
| Dal Pozzo, S | 1 |
| Alterini, R | 1 |
| Carrai, V | 1 |
| Puccini, B | 1 |
| Bosi, A | 1 |
| Shohat, B | 1 |
| Gitter, S | 1 |
| Lavie, D | 1 |
| Han, T | 4 |
| Sokal, JE | 3 |
| Silber, R | 1 |
| Ellison, GW | 1 |
| Myers, LW | 1 |
| Geerts, ML | 1 |
| Hamers, J | 1 |
| Schwarze, EW | 1 |
| Kint, A | 1 |
| Roels, H | 1 |
| Lennert, K | 1 |
| Chaplin, H | 1 |
| Ideström, K | 1 |
| Kimby, E | 2 |
| Björkholm, M | 2 |
| Mellstedt, H | 1 |
| Engstedt, L | 1 |
| Gahrton, G | 2 |
| Johansson, B | 2 |
| Killander, D | 1 |
| Robérts, KH | 1 |
| Stalfelt, AM | 1 |
| Udén, AM | 1 |
| Wadman, B | 1 |
| Wählby, S | 2 |
| Glimelius, B | 1 |
| Hagberg, H | 1 |
| Johansson, H | 1 |
| Juliusson, G | 1 |
| Järnmark, M | 1 |
| Löfvenberg, E | 1 |
| Lennard, AL | 2 |
| Carey, P | 1 |
| Lucraft, H | 1 |
| Evans, RG | 2 |
| Economopoulos, T | 1 |
| Stathakis, N | 1 |
| Constantinidou, M | 1 |
| Papageorgiou, E | 1 |
| Anastassiou, C | 1 |
| Raptis, S | 1 |
| Wells, P | 1 |
| Wotherspoon, A | 1 |
| Burnet, NG | 1 |
| Tobias, JS | 1 |
| Iaffaioli, RV | 1 |
| Frasci, G | 1 |
| Palmieri, G | 1 |
| Tagliaferri, P | 1 |
| Montesarchio, V | 1 |
| Pagliarulo, C | 1 |
| Tortoriello, A | 1 |
| Facchini, G | 1 |
| Matano, E | 1 |
| Lauria, R | 1 |
| Bernard, T | 1 |
| Johnson, SA | 1 |
| Prentice, AG | 1 |
| Jones, L | 2 |
| Phillips, MJ | 1 |
| Newland, AC | 2 |
| Kelsey, SM | 2 |
| Hudson, GV | 1 |
| Jelliffe, AM | 1 |
| Cowley, NC | 1 |
| Neill, SM | 1 |
| Staughton, RC | 1 |
| Fontana, S | 1 |
| Roggero, E | 2 |
| Pedrinis, E | 2 |
| Pampallona, S | 1 |
| Tefferi, A | 1 |
| Witzig, TE | 1 |
| Reid, JM | 1 |
| Li, CY | 1 |
| Ames, MM | 1 |
| Molica, S | 1 |
| Tucci, L | 1 |
| Levato, D | 1 |
| Levato, L | 1 |
| Manfredi, L | 1 |
| Haak, HL | 1 |
| Gerrits, WB | 1 |
| Wijermans, PW | 1 |
| Kerkhofs, H | 1 |
| Joseph, G | 1 |
| Hadley, T | 1 |
| Djulbegovic, B | 1 |
| Hamm, J | 1 |
| Seeger, J | 1 |
| Blumenreich, M | 1 |
| Woodcock, T | 1 |
| Avilés, A | 1 |
| Talavera, A | 1 |
| Guzmán, R | 1 |
| Cuadra, I | 1 |
| Vail, DM | 1 |
| Kisseberth, WC | 1 |
| Obradovich, JE | 1 |
| Moore, FM | 1 |
| London, CA | 1 |
| MacEwen, EG | 2 |
| Ritter, MA | 1 |
| Korobko, VB | 1 |
| Chernyĭ, VA | 1 |
| Valetskiĭ, VL | 1 |
| Rozumiĭ, DA | 1 |
| Gunina, LM | 1 |
| Falk, S | 1 |
| Walther, F | 1 |
| Denk, R | 1 |
| Wyllie, AR | 1 |
| Bayliff, CD | 1 |
| Kovacs, MJ | 1 |
| Salloum, E | 1 |
| Khan, KK | 1 |
| Cooper, DL | 1 |
| Gressin, R | 1 |
| Legouffe, E | 1 |
| Leroux, D | 1 |
| Jacob, MC | 1 |
| Swiercz, P | 1 |
| Peoch, M | 1 |
| Capdevilla, V | 1 |
| Rossi, JF | 1 |
| Thyss, A | 1 |
| Sotto, JJ | 1 |
| Cameron, DA | 1 |
| Leonard, RC | 4 |
| Cook, MK | 1 |
| Dawes, PJ | 1 |
| Dawson, AA | 2 |
| Harris, AL | 1 |
| Heppleston, A | 1 |
| Horne, CH | 1 |
| Krajewski, AS | 1 |
| MacGillivray, JB | 1 |
| Mackie, MJ | 1 |
| Parker, AC | 2 |
| Roberts, JT | 1 |
| Thompson, WD | 1 |
| Piatelli, A | 1 |
| Croce, A | 1 |
| Tete, S | 1 |
| Artese, L | 1 |
| Pinotti, G | 1 |
| Pascarella, A | 1 |
| Bertoni, F | 1 |
| Savio, A | 1 |
| Savio, E | 1 |
| Capella, C | 1 |
| Saletti, P | 1 |
| Morandi, E | 1 |
| Santandrea, G | 1 |
| Khan, MA | 1 |
| Hellawell, GO | 1 |
| Nargund, VH | 1 |
| Shammas, FV | 1 |
| Heikkilä, R | 1 |
| Sternberg, AJ | 1 |
| Matutes, E | 1 |
| Killick, S | 1 |
| Wotherspoon, AC | 1 |
| Catovsky, D | 1 |
| Gandarillas, MA | 1 |
| Conde, E | 1 |
| Mazorra, F | 1 |
| Cuadrado, MA | 1 |
| Baro, J | 1 |
| Garijo, J | 1 |
| Recio, M | 1 |
| Richard, C | 1 |
| Iriondo, A | 1 |
| Zubizarreta, A | 1 |
| Enzenauer, RW | 1 |
| Brozetti, JJ | 1 |
| Dragoo, RA | 1 |
| Tomlinson, J | 1 |
| Tighe, M | 1 |
| Johnson, S | 1 |
| Stone, R | 1 |
| Nicholson, AG | 1 |
| Rule, S | 1 |
| Várkonyi, J | 1 |
| Zalatnai, A | 1 |
| Timár, J | 1 |
| Matolcsi, A | 1 |
| Falus, A | 1 |
| Bencsáth, M | 1 |
| László, V | 1 |
| Pócsik, E | 1 |
| Kotlán, B | 1 |
| Császár, A | 1 |
| Soukop, M | 1 |
| Tinegate, H | 1 |
| Shamash, J | 1 |
| Walewski, J | 1 |
| Apostolidis, J | 1 |
| Wilson, AM | 1 |
| Foran, JM | 1 |
| Gupta, RK | 1 |
| Rohatiner, AZ | 2 |
| Lister, TA | 2 |
| Jourdan, E | 1 |
| Topart, D | 1 |
| Pinzani, V | 1 |
| Jourdan, J | 1 |
| Morcos, F | 1 |
| Smith, E | 1 |
| Siemens, HJ | 1 |
| Gerke, P | 1 |
| Steinhoff, J | 1 |
| Roth-Isigkeit, A | 1 |
| Wagner, K | 1 |
| Brückner, S | 1 |
| Mounter, PJ | 1 |
| Schmidt, CG | 1 |
| Kuenn, JW | 1 |
| Weber, R | 1 |
| Teague, PO | 1 |
| Keitt, AS | 1 |
| Menefee, MG | 1 |
| Zellner, DC | 1 |
| Wright, RC | 1 |
| Patnaik, AK | 1 |
| Wilkins, RJ | 1 |
| Mattsson, W | 1 |
| von Eyben, F | 1 |
| Turesson, I | 1 |
| Icli, F | 1 |
| Costello, W | 1 |
| Berard, CW | 2 |
| Bennett, JM | 1 |
| Carbone, PP | 1 |
| Farr, MJ | 1 |
| Newling, DW | 1 |
| Raper, C | 1 |
| Kaufman, JH | 1 |
| Ezdinli, E | 2 |
| Aungst, CW | 5 |
| Pocock, S | 1 |
| Silverstein, M | 1 |
| Horton, J | 1 |
| Bennett, J | 1 |
| Bakemeier, R | 1 |
| Stolbach, L | 1 |
| Perlia, C | 1 |
| Brunk, SF | 1 |
| Lenhard, RE | 2 |
| Klaassen, DJ | 1 |
| Richter, P | 2 |
| Carbone, P | 1 |
| Hill, BH | 1 |
| Mittelman, A | 1 |
| Murphy, GP | 1 |
| Móller, TR | 1 |
| Brandt, L | 1 |
| Kónyves, I | 1 |
| Lindberg, G | 1 |
| Platanias, LC | 1 |
| Putterman, AM | 1 |
| Vijayakumar, S | 1 |
| Recant, W | 1 |
| Weichselbaum, RR | 1 |
| Bitran, JD | 1 |
| Coma, A | 1 |
| Jonte, F | 1 |
| Zanabili, Y | 1 |
| Soto, I | 1 |
| Fanjul, F | 1 |
| Carrera, D | 1 |
| Rayón, C | 1 |
| Luño, E | 1 |
| Jalón, S | 1 |
| Pinto, V | 1 |
| O'Brien, ME | 1 |
| Easterbrook, P | 1 |
| Powell, J | 1 |
| Blackledge, GR | 1 |
| MacLennan, IC | 1 |
| Loos, U | 1 |
| Musch, E | 1 |
| Malek, M | 1 |
| Riedel, E | 1 |
| Thomas, DW | 1 |
| Gray, W | 1 |
| Tate, RJ | 1 |
| Ba-Thike, K | 1 |
| Oo, N | 1 |
| Watkin, SW | 1 |
| Green, JA | 1 |
| Daxecker, F | 1 |
| Neuner, HP | 1 |
| Kienpointner, G | 1 |
| Stühlinger, W | 1 |
| Gisselbrecht, C | 1 |
| Lepage, E | 1 |
| Sebban, C | 1 |
| Coiffier, B | 1 |
| Jahn, H | 1 |
| Ruffert, K | 1 |
| Syrbe, G | 1 |
| Kühn, R | 1 |
| Jorke, D | 1 |
| Szántó, I | 1 |
| Fleischmann, T | 1 |
| Eckhardt, S | 1 |
| Clark, RH | 1 |
| Dimitrov, NV | 1 |
| Axelson, JA | 1 |
| Charamella, LJ | 1 |
| Stott, PB | 1 |
| Chisesi, T | 2 |
| Capnist, G | 2 |
| Vespignani, M | 2 |
| Dini, E | 1 |
| Hitchins, RN | 1 |
| Hocker, GA | 1 |
| Thomson, DB | 1 |
| Allan, NC | 1 |
| McGillivray, JB | 1 |
| Cetto, G | 1 |
| Steward, WP | 1 |
| Crowther, D | 2 |
| McWilliam, LJ | 1 |
| Jones, JM | 1 |
| Deakin, DP | 1 |
| Todd, ID | 1 |
| Blackledge, G | 1 |
| Wagstaff, J | 2 |
| Scarffe, JH | 2 |
| Harris, M | 1 |
| Bird, MC | 1 |
| Bosanquet, AG | 1 |
| Forskitt, S | 1 |
| Gilby, ED | 1 |
| Portlock, CS | 1 |
| Fischer, DS | 1 |
| Cadman, E | 1 |
| Lundberg, WB | 1 |
| Levy, A | 1 |
| Bobrow, S | 1 |
| Bertino, JR | 1 |
| Farber, L | 1 |
| Richards, MA | 1 |
| Barnett, MJ | 1 |
| Stansfeld, AG | 1 |
| Steigbigel, RT | 1 |
| Kim, H | 1 |
| Potolsky, A | 1 |
| Schrier, SL | 1 |
| Armstrong, JG | 1 |
| Druet, P | 1 |
| Dryll, A | 1 |
| Ryckewaert, A | 1 |
| de Sèze, S | 1 |
| Kahn, MF | 1 |
| Bessot, M | 1 |
| Brouant, JF | 1 |
| Laurent, J | 1 |
| Macinot, C | 1 |
| Kourilsky, R | 1 |
| Kourilsky, S | 1 |
| Piéron, R | 1 |
| Lesobre, B | 1 |
| Bernueau, J | 1 |
| Hunold, W | 1 |
| Gunz, FW | 1 |
| Levi, JA | 1 |
| Lind, DE | 1 |
| Vincent, PC | 1 |
| Reilly, CJ | 1 |
| Slack, NH | 1 |
| Webster, J | 1 |
| Pinkhas, J | 1 |
| Oliver, I | 1 |
| De Vries, A | 1 |
| Spitzer, SA | 1 |
| Henig, E | 1 |
| Fayemi, AO | 1 |
| Williams, J | 1 |
| Cuttner, J | 1 |
| Stojcevski, T | 1 |
| Mukherji, B | 1 |
| Yagoda, A | 1 |
| Lee, BJ | 1 |
| Krakoff, IH | 1 |
| Zittoun, R | 1 |
| Debré, P | 1 |
| Gardais, J | 1 |
| Thuau, FP | 1 |
| Renier, JC | 1 |
| Simon, F | 1 |
| Halkin, H | 1 |
| Meytes, D | 1 |
| Militeanu, J | 1 |
| Ramot, B | 1 |
| Berceanu, S | 1 |
| Sighetea, E | 1 |
| Gociu, M | 1 |
| Ghetie, I | 1 |
| Stoica, GH | 1 |
| Voiosu, R | 1 |
| McElwain, TJ | 1 |
| Jacobs, EM | 1 |
| Peters, FC | 1 |
| Luce, JK | 1 |
| Zippin, C | 1 |
| Rosenberg, SA | 1 |
| Kaung, DT | 1 |
| Wittington, RM | 1 |
| Spencer, H | 1 |
| Patno, ME | 1 |
| Calamera, JC | 1 |
| Morgenfeld, MC | 2 |
| Kierszenbaum, AL | 1 |
| Lavieri, JC | 1 |
| Mancini, RE | 1 |
| Cohen, ML | 1 |
| Weiss, EB | 1 |
| Miller, DG | 1 |
| Presant, CA | 1 |
| Wiernik, PH | 1 |
| Serpick, AA | 1 |
| Helft, F | 1 |
| Bomchil, G | 1 |
| Osterberg, G | 1 |
| Rausing, A | 1 |
| Hartwich, G | 1 |
| Butzler, W | 1 |
| Henefer, EP | 1 |
| Nelson, JF | 1 |
| Beaupre, EM | 1 |
| Gosselin, G | 1 |
| Neemeh, J | 1 |
| Long, LA | 1 |
| Pretty, H | 1 |
| Lefebvre, R | 1 |
| White, LP | 1 |
| Owens, AH | 1 |
| Kissel, P | 1 |
| Debry, G | 1 |
| Royer, R | 1 |
| Picard, L | 1 |
| Lewis, FB | 1 |
| Schwartz, RS | 1 |
| Dameshek, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| US Post-Marketing Retrospective Observational Safety Study of Moxetumomab Pasudotox-tdfk (LUMOXITI)(TM)[NCT04125290] | 2 participants (Actual) | Observational | 2019-12-09 | Terminated (stopped due to Study stopped due to lack of recruitment.) | |||
| Immune Reconstitution With Blinatumomab Expanded T-cells (BET) After First-line Treatment With Fludarabine-Cyclophosphamide-Rituximab or Bendamustine-Rituximab in CD20+ Indolent Non-Hodgkin Lymphomas/Chronic Lymphocytic Leukemia: a Phase I Study[NCT03823365] | Phase 1 | 19 participants (Actual) | Interventional | 2018-12-17 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for chlorambucil and Diffuse Mixed Small and Large Cell Lymphoma
| Article | Year |
|---|---|
Fludarabine combination therapy for the treatment of chronic lymphocytic leukemia.
Topics: Adolescent; Adult; Aged; Alemtuzumab; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antibodie | 2002 |
Economic assessment on the management of chronic lymphocytic leukaemia.
Topics: Algorithms; Antibodies, Monoclonal; Antineoplastic Agents; Chlorambucil; Cost-Benefit Analysis; Heal | 2005 |
Immunosuppressive drugs in multiple sclerosis: pro and con.
Topics: Adrenocorticotropic Hormone; Alkylating Agents; Antimetabolites; Azathioprine; Chlorambucil; Cycloph | 1980 |
[Metastatic malignant melanoma in treated non-Hodgkin's lymphoma].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Humans; Lymph Nodes; Lymphatic | 1996 |
Chlorambucil-induced seizures.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Chlorambucil; Humans; Lymphoma, Non-Hodg | 1997 |
Chlorambucil.
Topics: Animals; Carcinogens; Chlorambucil; Drug Evaluation, Preclinical; Female; Fetus; Humans; Lethal Dose | 1975 |
32 trials available for chlorambucil and Diffuse Mixed Small and Large Cell Lymphoma
| Article | Year |
|---|---|
Randomized phase III study for the treatment of advanced indolent non-Hodgkin's lymphomas (NHL) and mantle cell lymphoma: chemotherapy versus chemotherapy plus rituximab.
Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplas | 2003 |
Long-term effect of a watch and wait policy versus immediate systemic treatment for asymptomatic advanced-stage non-Hodgkin lymphoma: a randomised controlled trial.
Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Cause of Death; Chlorambuci | 2003 |
Chlorambucil in combination with induction and maintenance rituximab is feasible and active in indolent non-Hodgkin's lymphoma.
Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined | 2003 |
A phase I/II study examining pentostatin, chlorambucil, and theophylline in patients with relapsed chronic lymphocytic leukemia and non-Hodgkin's lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Diseas | 2006 |
The addition of oral idarubicin to a chlorambucil/dexamethasone combination has a significant impact on time to treatment failure but none on overall survival in patients with low grade non-Hodgkin's lymphoma: Results of the Scotland and Newcastle Lymphom
Topics: Administration, Oral; Adolescent; Adult; Aged; Chlorambucil; Dexamethasone; Disease Progression; Dru | 2006 |
Rituximab and chlorambucil as first-line treatment for low-grade ocular adnexal lymphomas.
Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplas | 2007 |
Treatment of chronic lymphocytic leukaemia and well-differentiated lymphocytic lymphoma with continuous low- or intermittent high-dose prednimustine versus chlorambucil/prednisolone.
Topics: Adult; Aged; Chlorambucil; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; | 1982 |
Chlorambucil/prednisone vs. CHOP in symptomatic low-grade non-Hodgkin's lymphomas: a randomized trial from the Lymphoma Group of Central Sweden.
Topics: Actuarial Analysis; Aged; Antineoplastic Combined Chemotherapy Protocols; Cause of Death; Chlorambuc | 1994 |
Autologous bone marrow transplantation in poor-risk high-grade non-Hodgkin's lymphoma in first complete remission. Newcastle and Northern Lymphoma Group.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Blood Platelets; Bone | 1994 |
Chlorambucil, vincristine and cytarabine (COA) treatment of low grade lymphomas.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chlorambucil; Cytara | 1995 |
Mitoxantrone, chlorambucil and prednisolone in the treatment of non-Hodgkin's lymphoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Female; Humans; Lymphoma, | 1994 |
A British National Lymphoma Investigation randomised trial of single agent chlorambucil plus radiotherapy versus radiotherapy alone in low grade, localised non-Hodgkins lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Chlorambucil; Female; Follow-Up Studies; Humans; Lymphoma, Non-Hodgk | 1994 |
Phase I study of combined 2-chlorodeoxyadenosine and chlorambucil in chronic lymphoid leukemia and low-grade lymphoma.
Topics: 2-Chloroadenosine; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chloramb | 1994 |
Combined use of interferon alpha-2, chlorambucil and prednisone in previously treated patients with low-grade non-Hodgkin's lymphomas. Results of a phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Female; Humans; Interfero | 1993 |
Mitoxantrone, teniposide, chlorambucil and prednisone (MVLP) for relapsed non-Hodgkin's lymphoma. The impact of advanced age and performance status.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophospha | 1993 |
High-dose chlorambucil and dexamethasone for relapsed non-Hodgkin's lymphomas.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Dexame | 1993 |
Treatment of refractory low grade lymphoma with chlorambucil alternating with interferon and radiotherapy.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined Moda | 1995 |
Treatment of mantle-cell lymphomas with the VAD +/- chlorambucil regimen with or without subsequent high-dose therapy and peripheral blood stem-cell transplantation.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined Modality Therapy; Cyclo | 1997 |
CHOP-based chemotherapy is as effective as alternating PEEC/CHOP chemotherapy in a randomised trial in high-grade non-Hodgkin's lymphoma. Scotland and Newcastle Lymphoma Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cyclophosphami | 1997 |
Clinical features, treatment and outcome in a series of 93 patients with low-grade gastric MALT lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antineoplastic Agents, Alkylating; Antineopla | 1997 |
Primary treatment of low-grade non-Hodgkin's lymphoma using an all oral anthracycline-containing regimen, chlorambucil, idarubicin, dexamethasone (CID)--a phase II study.
Topics: Administration, Oral; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy | 2000 |
Low-dose continuous chemotherapy (LBCMVD-56) for refractory and relapsing lymphoma.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; De | 2000 |
A phase II clinical trial of prednimustine. Clinical screening cooperative group of E.O.R.T.C.
Topics: Adolescent; Adult; Aged; Chlorambucil; Clinical Trials as Topic; Female; Humans; Leukemia, Lymphoid; | 1977 |
Lymphosarcoma. A comparison of extended to conservative chemotherapy.
Topics: Adult; Aged; Carmustine; Chlorambucil; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; | 1976 |
Treatment of chronic lymphocytic leukemia and lymphosarcoma with a new chlorambucil ester of prednisolone (Leo 1031) (NSC-134087).
Topics: Chlorambucil; Clinical Trials as Topic; Female; Humans; Leukemia, Lymphoid; Lymphoma, Non-Hodgkin; P | 1975 |
Comparative pharmacokinetics of chlorambucil and prednimustine after oral administration.
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chlora | 1991 |
[Low-grade non-Hodgkin's lymphoma in the adult: new therapeutic approaches].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Doxorubicin; | 1987 |
Prednimustine treatment in malignant lymphomas.
Topics: Adult; Aged; Chlorambucil; Clinical Trials as Topic; Female; Hodgkin Disease; Humans; Lymphoma, Non- | 1989 |
Interferon alfa-2b and chlorambucil in the treatment of non-Hodgkin's lymphoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Clinical Trials as Topic; Female | 1987 |
Maintenance chlorambucil after CVP in the management of advanced stage, low-grade histologic type non-Hodgkin's lymphoma. A randomized prospective study with an assessment of prognostic factors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Drug Evaluation; Fem | 1988 |
Mechlorethamine HCl and cyclophosphamide in the treatment of Hodgkin's disease and the lymphomas.
Topics: Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Dosage Forms; Follow-Up Studies; Hodgkin D | 1968 |
Comparison of chlorambucil and streptonigrin (NSC-45383) in the treatment of malignant lymphomas.
Topics: Antibiotics, Antineoplastic; Bone Marrow; Chlorambucil; Clinical Trials as Topic; Digestive System; | 1969 |
115 other studies available for chlorambucil and Diffuse Mixed Small and Large Cell Lymphoma
| Article | Year |
|---|---|
Demographics and Outome in Paediatric Non-Hodgkin Lymphoma: Single Centre Experience at The Children Hospital Lahore, Pakistan.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Child; Child, Preschoo | 2018 |
Feline small cell lymphosarcoma versus inflammatory bowel disease: treatment and prognosis.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Cat Diseases; Cats; Chlorambucil; Diet; Gastr | 2013 |
Chlorambucil-rituximab as first-line therapy in patients affected by follicular non-Hodgkin's lymphoma: a retrospective single-centre study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Chlorambucil; Female; Humans; Lym | 2015 |
Clinical investigations in aggressive non-Hodgkin lymphoma.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antineoplasti | 2008 |
Increased incidence of transformation and myelodysplasia/acute leukemia in patients with Waldenström macroglobulinemia treated with nucleoside analogs.
Topics: Adult; Aged; Aged, 80 and over; Cell Transformation, Neoplastic; Chlorambucil; Cladribine; Female; F | 2009 |
Chlorambucil and acute intermittent porphyria.
Topics: Antineoplastic Agents, Alkylating; Chlorambucil; Female; Humans; Lymphoma, Non-Hodgkin; Middle Aged; | 2002 |
Chemotherapy of malignant disease. II. Diseases of lymphoid tissue and bone marrow.
Topics: Adrenal Cortex Hormones; Aged; Bone Marrow; Busulfan; Chlorambucil; Cyclophosphamide; Hodgkin Diseas | 1962 |
THE MALIGNANT LYMPHOMAS.
Topics: Adrenal Cortex Hormones; Chlorambucil; Cyclophosphamide; Hodgkin Disease; Humans; Lymphoma; Lymphoma | 1963 |
ENTERIC PROTEIN LOSS WITH HYPOPROTEINEMIA IN DIFFUSE LYMPHOSARCOMA OF THE BOWEL.
Topics: Aged; Biopsy; Blood Protein Disorders; Chlorambucil; Edema; Humans; Hypocalcemia; Hypoproteinemia; I | 1963 |
CLINICAL EVALUATION OF URACIL MUSTARD.
Topics: Anemia; Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Female; Hodgkin Disease; Humans; Kidn | 1963 |
THE RETICULOSES.
Topics: Adrenal Cortex Hormones; Chlorambucil; Cyclophosphamide; Dermatitis, Exfoliative; Genetic Diseases, | 1964 |
[CURRENT PRACTICE IN THE TREATMENT OF TUMORS WITH INTRA-ARTERIAL INJECTIONS OF ANTINEOPLASTIC SUBSTANCES].
Topics: Aminopterin; Antineoplastic Agents; Carcinoma; Chemotherapy, Cancer, Regional Perfusion; Chlorambuci | 1963 |
WEEKLY HIGH-DOSAGE GLUCOCORTICOSTEROID TREATMENT OF LYMPHOCYTIC LEUKEMIAS AND LYMPHOMAS.
Topics: Anemia; Anemia, Hemolytic; Betamethasone; Chlorambucil; Dexamethasone; Geriatrics; Humans; Leukemia; | 1964 |
PHAGOCYTOSIS IN RETICULUM CELL SARCOMA.
Topics: Adolescent; Black People; Child; Chlorambucil; Cyclophosphamide; Dactinomycin; Geriatrics; Leukemia; | 1964 |
SPINAL-CORD COMPRESSION IN THE MALIGNANT LYMPHOMAS.
Topics: Chlorambucil; Hematopoiesis; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Mercaptopurin | 1964 |
[HISTOPATHOLOGICAL EFFECTS OF ANTINEOPLASTIC AGENTS ON MALIGNANT LYMPHOMA].
Topics: Antineoplastic Agents; Child; Chlorambucil; Cyclophosphamide; Dactinomycin; Geriatrics; Hodgkin Dise | 1964 |
LONG TERM RESULTS ACHIEVED WITH THE USE OF ALKYLATING AGENTS IN MALIGNANT LYMPHOMA AND HODGKIN'S DISEASE.
Topics: Alkylating Agents; Chlorambucil; Cyclophosphamide; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Larg | 1964 |
[ISOLATED PULMONARY LYMPHOCYTOSARCOMAS].
Topics: Bronchoscopy; Chlorambucil; Cyclophosphamide; Humans; Lung; Lung Neoplasms; Lymphoma, Non-Hodgkin; P | 1964 |
NONSURGICAL TREATMENT OF PULMONARY CANCER.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adrenal Cortex Hormones; Alkylating Agents; Antineoplastic Agen | 1964 |
CHROMOSOMES OF LYMPHOSARCOMA AND CANCER CELLS IN BONE MARROW.
Topics: Alkaloids; Antineoplastic Agents; Bone Marrow; Bone Marrow Examination; Chlorambucil; Chromosome Abe | 1964 |
THE MANAGEMENT OF LEUKEMIA AND LYMPHOMA.
Topics: Adrenal Cortex Hormones; Busulfan; Chlorambucil; Cortisone; Cyclophosphamide; Hodgkin Disease; Human | 1964 |
CHLORAMBUCIL THERAPY FOR LYMPHOMAS AND CHRONIC LYMPHOCYTIC LEUKEMIA.
Topics: Adrenal Cortex Hormones; Chlorambucil; Drug Synergism; Hodgkin Disease; Leukemia; Leukemia, Lymphocy | 1965 |
ESSENTIAL MACROGLOBULINEMIA. REPORT OF A CASE INCLUDING IMMUNOFLUORESCENT AND ELECTRON MICROSCOPIC STUDIES.
Topics: Blood Protein Electrophoresis; Bone Marrow Cells; Chlorambucil; Electrons; Fluorescent Antibody Tech | 1965 |
Effect of chlorambucil on synthesis of protein and nucleic acids in tumor-bearing mice.
Topics: Animals; Chlorambucil; Lymphoma, Non-Hodgkin; Mechlorethamine; Mice; Neoplasms; Nitrogen Mustard Com | 1960 |
[Results obtained with the use of chlorambucil in the treatment of malignant lymphopathies].
Topics: Chlorambucil; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodg | 1961 |
[Principles of treatment and military medical examination of the patients with indolent Non-Hodgkin's lymphomas].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cohort Studies; Combined Modalit | 2003 |
Urinary immunocytology for primary bladder B cell lymphoma.
Topics: Aged; Antigens, CD20; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocy | 2004 |
High dose chlorambucil in the treatment of lymphoid malignancies.
Topics: Antineoplastic Agents, Alkylating; Chlorambucil; Clinical Trials as Topic; Hodgkin Disease; Humans; | 2004 |
Effective treatment of indolent non-hodgkin's lymphomas with mitoxantrone, chlorambucil and prednisone.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Di | 2005 |
Necrobiotic xanthogranuloma associated with paraproteinemia and non-Hodgkin's lymphoma developing into chronic lymphocytic leukemia: the first case reported in the literature and review of the literature.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyc | 2006 |
Peripheral T-lymphocyte subsets in patients treated with Rituximab-Chlorambucil combination therapy for indolent NHL.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; CD4-Positive | 2006 |
Case of chlorambucil-induced seizure.
Topics: Aged; Chlorambucil; Humans; Lymphoma, Non-Hodgkin; Male; Seizures | 2006 |
Action of elatericin A on human leukemic and normal lymphocytes.
Topics: Aminopterin; Animals; Antineoplastic Agents; Azirines; Cathartics; Cell Nucleus; Chlorambucil; Cyclo | 1967 |
Complete remission in chronic lymphocytic leukemia and leukolymphosarcoma.
Topics: Aged; Chlorambucil; Female; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma, Non-Hodgkin; Male; Middl | 1967 |
Chronic lymphocytic leukemia in the elderly.
Topics: Aged; B-Lymphocytes; Chlorambucil; Diagnosis, Differential; Glucosephosphate Dehydrogenase; Humans; | 1982 |
Mycosis fungoides and lymphoplasmacytoid immunocytoma in the same patient. A case report.
Topics: Chlorambucil; Cytoplasm; Female; Hematologic Tests; Humans; Immunoglobulin lambda-Chains; Immunoglob | 1984 |
Lymphoma in primary chronic cold hemagglutinin disease treated with chlorambucil.
Topics: Anemia, Hemolytic, Autoimmune; Chlorambucil; Chronic Disease; Cold Temperature; Humans; Lymphoma, La | 1982 |
Cold agglutinin disease in non-Hodgkin's lymphoma.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Anemia, Hemolytic, Autoimmune; | 1995 |
Cutaneous B-cell lymphoma with subsequent laryngeal involvement.
Topics: Aged; Chlorambucil; Humans; Laryngeal Neoplasms; Lymphoma, B-Cell; Lymphoma, Non-Hodgkin; Male; Radi | 1995 |
Pemphigus foliaceus and non-Hodgkin's lymphoma.
Topics: Allopurinol; Chlorambucil; Drug Therapy, Combination; Female; Fluorescent Antibody Technique; Humans | 1994 |
Treatment and prognosis of centrocytic (mantle cell) lymphoma: a retrospective analysis of twenty-six patients treated in one institution.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Female | 1994 |
Assessment of potential doubling time (Tpot), argyrophilic nucleolar organizer regions (AgNOR), and proliferating cell nuclear antigen (PCNA) as predictors of therapy response in canine non-Hodgkin's lymphoma.
Topics: Animals; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Chloramb | 1996 |
[New approach to the treatment of primary malignant non-Hodgkin's lymphoma of the stomach].
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Ant | 1996 |
Myoclonus due to chlorambucil in two adults with lymphoma.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Chlorambucil; Female; Humans; Leukemia, Lymphocytic, | 1997 |
Primary non-Hodgkin's lymphoma of the mandible: a case report.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Cell Nucleolus; Cell Nucleus; Chlorambuc | 1997 |
Ureteric obstruction due to B-cell lymphoma.
Topics: Antineoplastic Agents, Alkylating; Chlorambucil; Humans; Lymphoma, B-Cell; Lymphoma, Non-Hodgkin; Ma | 1997 |
[Secondary myelodysplastic syndrome].
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Bone Marrow Transplantation; Chlorambucil; Cyclophos | 1997 |
Prolonged disease-free survival in relapsed/refractory low-grade lymphoma treated with fludarabine: a report of four cases.
Topics: Adult; Anthracyclines; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Comb | 1998 |
[Prognostic factors in low-grade lymphoma].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; B | 1998 |
Central retinal vein occlusion in a patient with IgG lambda monoclonal gammopathy.
Topics: Aged; Bone Marrow; Chlorambucil; Drug Therapy, Combination; Fluorescein Angiography; Humans; Hyperga | 1999 |
Interstitial pneumonitis following mitozantrone, chlorambucil and prednisolone (MCP) chemotherapy.
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Female; H | 1999 |
Secondary cutaneous infiltration in B cell chronic lymphocytic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Doxorubicin; Histidi | 2000 |
Chlorambucil/prednisone-induced seizures in a patient with non-Hodgkin's lymphoma.
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Drug | 2001 |
Sciatica or spinal lymphoma.
Topics: Aged; Antineoplastic Agents, Alkylating; Chlorambucil; Diagnosis, Differential; Humans; Lymphoma, B- | 2002 |
A prolonged APTT in a patient with a low grade malignant NHL - a case report.
Topics: Anemia; Antineoplastic Combined Chemotherapy Protocols; Autoantibodies; Blood Coagulation Factors; C | 2002 |
High-dose chlorambucil for the treatment of chronic lymphocytic leukaemia and low-grade non-Hodgkin's lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Anemia, Hemolytic, Autoimmune; Antineoplastic Agents, Alkylating; Ch | 2002 |
[Chemotherapy in non-Hodgkin's lymphomas (author's transl)].
Topics: Antineoplastic Agents; Bleomycin; Burkitt Lymphoma; Chlorambucil; Cyclophosphamide; Doxorubicin; Dru | 1977 |
Cryopathic gangrene with an IgM lambda cryoprecipitating cold agglutinin.
Topics: Adult; Agglutinins; Autoantibodies; Breast Neoplasms; Chlorambucil; Cryoglobulins; Female; Gangrene; | 1978 |
The Sézary syndrome. A case with fetal-type glycogen and lymphocytic lymphoma.
Topics: Chlorambucil; Cytoplasmic Granules; Dermatitis, Exfoliative; Glycogen; Humans; Lymphoma, Non-Hodgkin | 1978 |
Diagnosis and treatment of canine hematopoietic neoplasms.
Topics: Animals; Chlorambucil; Dog Diseases; Dogs; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma | 1977 |
Prednimustine (NSC-134087, Leo 1031) treatment of lymphocytic and lymphocytic-histiocytic lymphomas.
Topics: Bone Marrow; Chlorambucil; Female; Humans; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; M | 1978 |
Diffuse well-differentiated lymphocytic lymphoma (DLWD): response and survival.
Topics: Aged; Antineoplastic Agents; Carmustine; Cell Differentiation; Chlorambucil; Cyclophosphamide; Drug | 1978 |
Simple chemotherapy for bladder lymphoma with bilateral hydronephrosis.
Topics: Chlorambucil; Humans; Hydronephrosis; Lymphoma, Non-Hodgkin; Male; Middle Aged; Prednisolone; Urinar | 1978 |
Comparison of intensive versus moderate chemotherapy of lymphocytic lymphomas: a progress report.
Topics: Adult; Aged; Chlorambucil; Cyclophosphamide; Drug Combinations; Ethylnitrosourea; Evaluation Studies | 1976 |
Immunosuppressive drug therapy as a potentiator of skin tumours in five patients with lymphoma.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Chlorambucil; H | 1976 |
Therapeutic effect of Leo 1031, an alkylating corticosteroid ester; in lymphoproliferative disorders. II. Lymphocytic lymphoma.
Topics: Adult; Aged; Bone Marrow; Chlorambucil; Drug Evaluation; Drug Therapy, Combination; Esters; Female; | 1975 |
Treatment and prognosis of orbital non-Hodgkin's lymphomas.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cyclophosphamide; Cyt | 1992 |
[Low-grade non-Hodgkin's lymphomas. Study of 73 cases].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclop | 1992 |
The natural history of low grade non-Hodgkin's lymphoma and the impact of a no initial treatment policy on survival.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophospha | 1991 |
Non-Hodgkin's lymphoma presenting at the site of a recent dental extraction: a report of two cases.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Humans; Jaw Neoplasms; Ly | 1991 |
Non-Hodgkin's lymphoma in pregnancy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Female; Fetus | 1990 |
Non-Hodgkin's lymphoma. A four-drug regimen suitable for elderly patients with advanced disease.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Drug Evaluation; Female; Humans; | 1990 |
[Papilledema and macular edema as first symptom of non-Hodgkin's lymphoma].
Topics: Aged; Chlorambucil; Edema; Fluorescein Angiography; Fundus Oculi; Humans; Lymphoma, Non-Hodgkin; Mac | 1990 |
Results of treating stage III and IV malignant non-Hodgkin's lymphomas (NHL).
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cyclophosphamide; Doxorubic | 1988 |
A phase II trial of intermittent leukocyte interferon and high dose chlorambucil in the treatment of non-Hodgkin's lymphoma resistant to conventional therapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Drug A | 1989 |
The role of interferon alfa-2b and chlorambucil in the treatment of non-Hodgkin's lymphoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Bone Marrow; Chlorambucil; Huma | 1988 |
Chlorambucil allergy--a series of three cases.
Topics: Aged; Chlorambucil; Drug Eruptions; Female; Humans; Lymphoma, Non-Hodgkin; Male; Middle Aged; Patch | 1987 |
Methylprednisolone, etoposide, vindesine, and chlorambucil (PEEC) alone or alternating with CHOP as initial or salvage therapy for non-Hodgkin's lymphoma.
Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamid | 1988 |
Long-term comparison of results of a drug sensitivity assay in vitro with patient response in lymphatic neoplasms.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Drug Screening | 1988 |
Clinical use of interferon alfa-2b (intron-A): the Manchester experience.
Topics: Chlorambucil; Combined Modality Therapy; Drug Evaluation; Humans; Infusions, Intravenous; Injections | 1987 |
High-dose pulse chlorambucil in advanced, low-grade non-Hodgkin's lymphoma.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Chlorambucil; Female; Humans; Lymphoma, Non-Ho | 1987 |
Chlorambucil and interferon for low grade non-Hodgkin's lymphoma.
Topics: Adult; Aged; Chlorambucil; Combined Modality Therapy; Humans; Interferon Type I; Lymphoma, Non-Hodgk | 1987 |
Acute myeloproliferative disorder following long-term chlorambucil therapy.
Topics: Biopsy; Bone Marrow; Chlorambucil; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Long | 1974 |
Current problems in the use of the oncolytic drugs.
Topics: Antineoplastic Agents; Busulfan; Carcinoma, Squamous Cell; Child; Chlorambucil; Choriocarcinoma; Dac | 1968 |
[Rheumatoid polyarthritis and chronic lymphoid leukemia. Studies of 7 cases of association of these 2 diseases].
Topics: Adult; Age Factors; Aged; Animals; Antibodies; Arthritis, Rheumatoid; Autoimmune Diseases; Chlorambu | 1969 |
[Lymphoid tumor of the stomach].
Topics: Chlorambucil; Female; Humans; Lymphocytosis; Lymphography; Lymphoma, Non-Hodgkin; Middle Aged; Stoma | 1969 |
[Waldenström's disease and pulmonary images. 2 cases].
Topics: Blood Sedimentation; Chlorambucil; Humans; Lung Neoplasms; Lymphoma, Non-Hodgkin; Male; Middle Aged; | 1970 |
[Letter: Progredient liver cirrhosis in chronic lymphatic leukemia].
Topics: Chlorambucil; Diabetes Complications; Hepatitis B; Humans; Leukemia, Lymphoid; Liver Cirrhosis; Lymp | 1974 |
Development of acute leukaemia in a patient with lymphosarcoma.
Topics: Autopsy; Bone Marrow; Bone Marrow Cells; Chlorambucil; Humans; Immunoglobulins; Karyotyping; Leukemi | 1973 |
Reticulum cell sarcoma. A review of radiotherapeutic experience.
Topics: Adolescent; Adult; Aged; Chlorambucil; Female; Follow-Up Studies; Humans; Lymphoma, Non-Hodgkin; Mal | 1972 |
Pulmonary nocardiosis complicating malignant lymphoma successfully treated with chemotherapy.
Topics: Agammaglobulinemia; Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Humans; Lung Diseases; Ly | 1973 |
Treatment of Hodgkin's disease and other malignant lymphomas.
Topics: Alkylating Agents; Antineoplastic Agents; Carmustine; Chlorambucil; Cyclohexanes; Cyclophosphamide; | 1973 |
Effect of BCG on delayed hypersensitivity responses of patients with neoplastic disease.
Topics: Animals; Antigen-Antibody Reactions; BCG Vaccine; Cattle; Chlorambucil; Cyclophosphamide; Hodgkin Di | 1973 |
Systemic Weber-Christian disease and thrombocythemia terminating in reticulum-cell sarcoma.
Topics: Adipose Tissue; Adult; Agammaglobulinemia; Arteritis; Arthritis, Rheumatoid; Autopsy; Blood Platelet | 1974 |
Haemolytic anaemia in malignant lymphoreticuloendothelial diseases.
Topics: Adult; Anemia, Hemolytic; Anemia, Hemolytic, Autoimmune; Autoantibodies; Bone Marrow Examination; Ce | 1974 |
A clinical study of the natural history of lymphosarcoma and reticulum cell sarcoma.
Topics: Adult; Aged; Chlorambucil; Cyclophosphamide; Female; Humans; Lymph Nodes; Lymphoma, Non-Hodgkin; Mal | 1974 |
[Small intestine lymphosarcoma after treatment of rheumatoid arthritis with chlorambucil].
Topics: Aged; Arthritis, Rheumatoid; Blood Cell Count; Chlorambucil; Female; Humans; Intestinal Neoplasms; I | 1972 |
Multiple lymphomatous polyposis of the gastrointestinal tract.
Topics: Autopsy; Biopsy; Celiac Disease; Chlorambucil; Gastrointestinal Neoplasms; Humans; Intestinal Polyps | 1973 |
Peculiar forms of monoclonal gammapathies.
Topics: Adrenal Cortex Hormones; Antigen-Antibody Complex; Blood Protein Disorders; Chlorambucil; Cryoglobul | 1973 |
Chemotherapy of the lymphomas.
Topics: Adult; Burkitt Lymphoma; Child; Chlorambucil; Cyclophosphamide; Doxorubicin; Drug Therapy, Combinati | 1974 |
Contribution of lymphangiography to our understanding of lymphoma.
Topics: Chlorambucil; Hodgkin Disease; Humans; Lymphography; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymp | 1968 |
Effect of chlorambucil on spermatogenesis in the human with malignant lymphoma.
Topics: Adolescent; Adult; Biopsy; Chlorambucil; Hodgkin Disease; Humans; Infertility, Male; Lymphoma; Lymph | 1970 |
Pneumocystitis carinii pneumonia: percutaneous lung biopsy and review of literature.
Topics: Adolescent; Adult; Agammaglobulinemia; Amphotericin B; Anuria; Azathioprine; Biopsy; Bis-Trimethylam | 1971 |
Alkylating agents and human spermatogenesis.
Topics: Adolescent; Adult; Alkylating Agents; Chlorambucil; Cyclophosphamide; Hodgkin Disease; Humans; Lymph | 1971 |
Disseminated extrapulmonary nocardiosis presenting as a renal abscess.
Topics: Abscess; Adult; Anemia, Hemolytic, Autoimmune; Autopsy; Brain Diseases; Chlorambucil; Diagnosis, Dif | 1970 |
[Different response of superficial and deep lymph nodes to drug therapy in malignant lymphoreticulopathy].
Topics: Aged; Chlorambucil; Cyclophosphamide; Female; Humans; Leukemia, Lymphoid; Lymph Nodes; Lymphoma, Lar | 1969 |
Reticulum cell sarcoma in Waldenström's macroglobulinemia after chlorambucil treatment.
Topics: Amyloidosis; Bone Marrow Cells; Bone Neoplasms; Chlorambucil; Female; Humans; Lymphoma, Non-Hodgkin; | 1970 |
[Secondary tumors in hemoblastoses during cytostatic treatment].
Topics: Adrenal Gland Neoplasms; Aged; Antineoplastic Agents; Bronchial Neoplasms; Busulfan; Carcinoma; Chlo | 1971 |
Spontaneous remission of leukemic lymphoproliferative disease.
Topics: Adult; Aged; Chlorambucil; Female; Humans; Leukemia, Lymphoid; Leukocyte Count; Lymphocytes; Lymphom | 1971 |
Palatal enlargement in chronic lymphocytic leukemia: report of case.
Topics: Aged; Chlorambucil; Edema; Humans; Leukemia, Lymphoid; Lymphatic Metastasis; Lymphoma, Non-Hodgkin; | 1970 |
[Appearance of acute myeloid leukemia during the development of lymphosarcoma].
Topics: Chlorambucil; Female; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Middle Aged | 1970 |
Leukemia and lymphoma.
Topics: Antineoplastic Agents; BCG Vaccine; Burkitt Lymphoma; Busulfan; Chlorambucil; Cyclophosphamide; Cyta | 1970 |
Recent advances in chemotherapy of lymphoma.
Topics: Alkylating Agents; Chlorambucil; Cyclophosphamide; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Larg | 1967 |
[Some reflections on the favorable effects of chlorambucil in unusual doses].
Topics: Aged; Chlorambucil; Female; Humans; In Vitro Techniques; Leukemia, Lymphoid; Lymphoma, Non-Hodgkin; | 1965 |
X-radiation and alkylating agents as possible "trigger" mechanisms in the autoimmune complications of malignant lymphophroliferative disease.
Topics: Adult; Aged; Anemia, Hemolytic, Autoimmune; Chlorambucil; Humans; Leukemia, Lymphoid; Lymphoma, Non- | 1966 |