chlorambucil has been researched along with Di Guglielmo Disease in 7 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirteen cases of acute nonlymphocytic leukemia occurred among 5455 patients, as compared to 0." | 1.26 | Acute leukemia after alkylating-agent therapy of ovarian cancer. ( Fraumeni, JF; Hoover, R; Reimer, RR; Young, RC, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Al-Hilali, MM | 1 |
| Edgcumbe, JO | 1 |
| Joyner, MV | 1 |
| Juul, K | 1 |
| Sørensen, P | 1 |
| Pedersen-Bjergaard, J | 1 |
| Jensen, MK | 1 |
| Khandekar, JD | 1 |
| Kurtides, ES | 1 |
| Stalzer, RC | 1 |
| Reimer, RR | 1 |
| Hoover, R | 1 |
| Fraumeni, JF | 1 |
| Young, RC | 1 |
| Cardamone, JM | 1 |
| Kimmerle, RI | 1 |
| Marshall, EY | 1 |
| Ruffner, BW | 1 |
| Laroche, C | 1 |
| Caquet, R | 1 |
| Remy, JM | 1 |
1 trial available for chlorambucil and Di Guglielmo Disease
| Article | Year |
|---|---|
Phase II trial of Prednimustine. Leo-1031 (NSC-134087) in acute non-lymphocytic leukemia.
Topics: Adult; Aged; Chlorambucil; Clinical Trials as Topic; Female; Humans; Leukemia, Erythroblastic, Acute | 1979 |
6 other studies available for chlorambucil and Di Guglielmo Disease
| Article | Year |
|---|---|
Chronic lymphatic leukaemia terminating as erythroleukaemia.
Topics: Aged; Chlorambucil; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Male; Time Factors | 1981 |
Acute erythroleukemia complicating prolonged chemotherapy for ovarian carcinoma.
Topics: Adult; Aged; Chlorambucil; Female; Humans; Leukemia, Erythroblastic, Acute; Long-Term Care; Ovarian | 1977 |
Acute leukemia after alkylating-agent therapy of ovarian cancer.
Topics: Acute Disease; Alkylating Agents; Altretamine; Chlorambucil; Cyclophosphamide; Female; Fluorouracil; | 1977 |
Development of acute erythroleukemia in B-cell immunoproliferative disorders after prolonged therapy with alkylating drugs.
Topics: Aged; Alkylating Agents; Biopsy; Bone Marrow; Chlorambucil; Female; Humans; Leukemia, Erythroblastic | 1974 |
Letter: Androgen role in erythroleukemia after treatment with alkylating agents.
Topics: Adult; Alkylating Agents; Androgens; Carcinoma, Intraductal, Noninfiltrating; Chlorambucil; Cytarabi | 1974 |
[Acute erythroleukemia following treatment of malignant exophthalmos with chlorambucil].
Topics: Acute Disease; Aged; Chlorambucil; Female; Graves Disease; Humans; Leukemia, Erythroblastic, Acute; | 1972 |