chlorambucil has been researched along with Dermatoses in 33 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A patient with an unusual variant of Sweet's syndrome, in which the course of the disease was chronic and relapsing, was treated successfully with intravenous methylprednisolone (pulse therapy)." | 7.67 | The use of pulse methylprednisolone and chlorambucil in the treatment of Sweet's syndrome. ( Callen, JP; Case, JD; Smith, SZ, 1989) |
| "5 of 6 adults with generalized granuloma annulare responded favorably to therapy with low-dose chlorambucil." | 7.66 | Low-dose chlorambucil in the treatment of generalized granuloma annulare. ( Kossard, S; Winkelmann, RK, 1979) |
| "The widely accepted standard therapy for cutaneous sarcoidosis includes corticosteroids, antimalarials, and methotrexate." | 4.84 | Cutaneous sarcoidosis therapy updated. ( Badgwell, C; Rosen, T, 2007) |
| " Methotrexate, azathioprine, mycophenolate mofetil, cyclosporin cyclophosphamide, chlorambucil, and other related drugs have potential benefits in the treatment of severe and/or recalcitrant rheumatic skin diseases." | 4.81 | Immunosuppressive and cytotoxic drugs in the treatment of rheumatic skin disorders. ( Callen, JP, 2001) |
| "A patient with an unusual variant of Sweet's syndrome, in which the course of the disease was chronic and relapsing, was treated successfully with intravenous methylprednisolone (pulse therapy)." | 3.67 | The use of pulse methylprednisolone and chlorambucil in the treatment of Sweet's syndrome. ( Callen, JP; Case, JD; Smith, SZ, 1989) |
| "5 of 6 adults with generalized granuloma annulare responded favorably to therapy with low-dose chlorambucil." | 3.66 | Low-dose chlorambucil in the treatment of generalized granuloma annulare. ( Kossard, S; Winkelmann, RK, 1979) |
| "Necrobiotic xanthogranuloma is a rare disease that is part of the non-Langerhans cell histiocytoses." | 3.01 | Therapy of necrobiotic xanthogranuloma - case series and review of the literature. ( Abeck, F; Booken, N; Ghandili, S; Hansen, I; Schneider, SW, 2023) |
| "Chlorambucil was effective on both diseases." | 2.38 | [Association of sarcoidosis and Waldenström's macroglobulinemia]. ( Boulitrop-Morvan, C; Camus, P; Collet, E; Dalac, S; Lambert, D, 1992) |
| "At the same time, she developed xanthomatous patches on the face, neck, and shoulders (Fig." | 1.33 | Necrobiotic xanthogranuloma associated with paraproteinemia and non-Hodgkin's lymphoma developing into chronic lymphocytic leukemia: the first case reported in the literature and review of the literature. ( Oumeish, I; Oumeish, OY; Salman, T; Sharaiha, A; Tarawneh, M, 2006) |
| "Multicentric Castleman's disease (MCD), or multicentric angiofollicular lymph node hyperplasia, is an uncommon lymphoproliferative disorder which typically present with constitutional symptoms, multicentric lymphadenopathy, hepatosplenomegaly, effusions, and ascites." | 1.29 | Presentation of multicentric Castleman's disease with sicca syndrome, cardiomyopathy, palmar and plantar rash. ( Cripe, LD; Hall, BD; Kingsmore, SF; Sheldon, EA; Silva, OE; St Clair, EW, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (69.70) | 18.7374 |
| 1990's | 4 (12.12) | 18.2507 |
| 2000's | 5 (15.15) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Hansen, I | 1 |
| Ghandili, S | 1 |
| Abeck, F | 1 |
| Booken, N | 1 |
| Schneider, SW | 1 |
| THIERS, H | 1 |
| COLOMB, D | 1 |
| FAYOLLE, J | 1 |
| ARCADIO, F | 1 |
| LIBANSKY, J | 1 |
| TRAPL, J | 1 |
| Oumeish, OY | 1 |
| Oumeish, I | 1 |
| Tarawneh, M | 1 |
| Salman, T | 1 |
| Sharaiha, A | 1 |
| Badgwell, C | 1 |
| Rosen, T | 1 |
| Calas, E | 1 |
| Bonerandi, JJ | 1 |
| Migozzi, B | 1 |
| Breton, A | 1 |
| Bourdet, D | 1 |
| Follana, J | 1 |
| Chanda, JJ | 1 |
| Callen, JP | 4 |
| Mutasim, D | 1 |
| Karban, AK | 1 |
| Goerz, G | 1 |
| Merk, H | 1 |
| Kingsmore, SF | 1 |
| Silva, OE | 1 |
| Hall, BD | 1 |
| Sheldon, EA | 1 |
| Cripe, LD | 1 |
| St Clair, EW | 1 |
| Flores, F | 1 |
| Kerdel, FA | 1 |
| Weinberg, JM | 1 |
| Ioffreda, M | 1 |
| White, SM | 1 |
| Rudolph, RI | 2 |
| Kramer, EM | 1 |
| Ruszczak, Z | 1 |
| Kossard, S | 2 |
| Winkelmann, RK | 2 |
| Collet, E | 1 |
| Boulitrop-Morvan, C | 1 |
| Dalac, S | 1 |
| Camus, P | 1 |
| Lambert, D | 1 |
| Mundell, AC | 1 |
| Mahoney, DH | 1 |
| McClain, KL | 1 |
| Hanson, IC | 1 |
| Taylor, LD | 1 |
| Steuber, CP | 1 |
| Case, JD | 1 |
| Smith, SZ | 1 |
| Ginsburg, WW | 1 |
| O'Duffy, JD | 2 |
| Morris, JL | 1 |
| Huston, KA | 1 |
| Pivetti Pezzi, P | 1 |
| Gasparri, V | 1 |
| De Liso, P | 1 |
| Catarinelli, G | 1 |
| Rathert, P | 1 |
| Terhorst, B | 1 |
| Lutzeyer, W | 1 |
| Dantzig, PI | 1 |
| Knisley, RE | 1 |
| Settipane, GA | 1 |
| Albala, MM | 1 |
| Davies, NE | 1 |
| Roenigk, HH | 1 |
| Hawk, WA | 1 |
| Rubens-Duval, A | 1 |
| Kaplan, G | 1 |
| Nobillot, A | 1 |
| Cuni, LJ | 1 |
| Grünwald, H | 1 |
| Rosner, F | 1 |
| Presant, CA | 1 |
| Wiernik, PH | 1 |
| Serpick, AA | 1 |
| Kostanecki, W | 1 |
| Mazurkiewicz, W | 1 |
| Górkiewicz, A | 1 |
| Zborzil, J | 1 |
| Vissian, L | 1 |
| Martin, J | 1 |
| Vaillaud, JC | 1 |
9 reviews available for chlorambucil and Dermatoses
| Article | Year |
|---|---|
Therapy of necrobiotic xanthogranuloma - case series and review of the literature.
Topics: Chlorambucil; Histiocytosis, Non-Langerhans-Cell; Humans; Necrobiotic Xanthogranuloma; Paraproteinem | 2023 |
Cutaneous sarcoidosis therapy updated.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Allopurinol; Animals; Anti-Inflammatory Agents | 2007 |
Other novel immunosuppressants.
Topics: Azathioprine; Chlorambucil; Cyclosporine; Humans; Immunosuppressive Agents; Methotrexate; Mycophenol | 2000 |
Immunosuppressive and cytotoxic drugs in the treatment of rheumatic skin disorders.
Topics: Adult; Alkylating Agents; Antimetabolites; Azathioprine; Child; Chlorambucil; Cladribine; Cyclophosp | 2001 |
[Treatment of autoimmune skin diseases].
Topics: Adrenal Cortex Hormones; Autoimmune Diseases; Azathioprine; Chlorambucil; Cyclophosphamide; Drug The | 1975 |
[Association of sarcoidosis and Waldenström's macroglobulinemia].
Topics: Chlorambucil; Female; Humans; Middle Aged; Sarcoidosis; Skin Diseases; Waldenstrom Macroglobulinemia | 1992 |
New therapeutic agents in veterinary dermatology.
Topics: 4-Quinolones; Animals; Anti-Infective Agents; Cat Diseases; Cats; Chlorambucil; Clofazimine; Dog Dis | 1990 |
Immunosuppressive and cytotoxic drugs: uses in the dermatologic patient.
Topics: Azathioprine; Chlorambucil; Cyclophosphamide; Drug Interactions; Female; Humans; Immunosuppressive A | 1990 |
Immunosuppressive and cytotoxic drugs in dermatology.
Topics: Animals; Antineoplastic Agents; Azathioprine; Azauridine; Bleomycin; Chlorambucil; Cyclophosphamide; | 1974 |
24 other studies available for chlorambucil and Dermatoses
| Article | Year |
|---|---|
[Profuse lymphodermia; cure by combined cortisone & chloraminophen].
Topics: Chlorambucil; Cortisone; Disease; Lymph Nodes; Lymphatic Diseases; Mechlorethamine; Nitrogen Mustard | 1959 |
Chlorambucil in erythrodermia.
Topics: Chlorambucil; Dermatitis, Exfoliative; Humans; Mechlorethamine; Nitrogen Mustard Compounds; Skin Dis | 1960 |
Necrobiotic xanthogranuloma associated with paraproteinemia and non-Hodgkin's lymphoma developing into chronic lymphocytic leukemia: the first case reported in the literature and review of the literature.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyc | 2006 |
[Perforating generalized granuloma annulare. A two case study (author's transl)].
Topics: Aged; Chlorambucil; Female; Granuloma; Heparin; Humans; Lipotropic Agents; Male; Skin Diseases | 1980 |
Necrotizing vasculitis (angiitis) with granulomatosis.
Topics: Azathioprine; Chlorambucil; Cyclophosphamide; Diagnosis, Differential; Granuloma, Lethal Midline; Gr | 1984 |
Granuloma annulare treated with chlorambucil: an 18-month follow-up.
Topics: Chlorambucil; Female; Granuloma; Humans; Middle Aged; Skin Diseases | 1983 |
[Medicamental immunosuppression in dermatology (author's transl)].
Topics: Autoimmune Diseases; Azathioprine; Chlorambucil; Collagen Diseases; Cyclophosphamide; Glucocorticoid | 1981 |
Presentation of multicentric Castleman's disease with sicca syndrome, cardiomyopathy, palmar and plantar rash.
Topics: Adult; Cardiomyopathies; Castleman Disease; Chlorambucil; Female; Foot; Hand; Humans; Prednisone; Sj | 1993 |
Purplish papules on the legs. Diagnosis: type I cryoglobulinemia in association with WM.
Topics: Aged; Betamethasone; Chlorambucil; Cryoglobulinemia; Diagnosis, Differential; Drug Therapy, Combinat | 2000 |
Low-dose chlorambucil in the treatment of generalized granuloma annulare.
Topics: Aged; Chlorambucil; Drug Evaluation; Female; Granuloma; Humans; Male; Middle Aged; Skin; Skin Diseas | 1979 |
Disseminated granuloma annulare treated with low-dose chlorambucil.
Topics: Chlorambucil; Female; Granuloma; Humans; Middle Aged; Skin Diseases | 1979 |
Response of generalized granuloma annulare to alkylating agents.
Topics: Aged; Alkylating Agents; Chlorambucil; Female; Granuloma; Humans; Male; Melphalan; Middle Aged; Pred | 1978 |
Acquired immune deficiency, myelodysplasia, and acute nonlymphocytic leukemia associated with monosomy 7 and t(3;3) (q21;q26) in a child with Langerhans cell histiocytosis.
Topics: Chlorambucil; Chromosome Deletion; Chromosomes, Human, Pair 3; Chromosomes, Human, Pair 7; Female; H | 1989 |
The use of pulse methylprednisolone and chlorambucil in the treatment of Sweet's syndrome.
Topics: Biopsy; Chlorambucil; Chronic Disease; Dermatitis; Female; Fever; Humans; Methylprednisolone; Middle | 1989 |
Multicentric reticulohistiocytosis: response to alkylating agents in six patients.
Topics: Adult; Aged; Alkylating Agents; Arthritis; Chlorambucil; Cyclophosphamide; Drug Therapy, Combination | 1989 |
Prognosis in Behcet's disease.
Topics: Adolescent; Adult; Behcet Syndrome; Central Nervous System Diseases; Chlorambucil; Eye Diseases; Fem | 1985 |
[Bleomycin for malignant tumours of the genitals of the male (author's transl)].
Topics: Adrenal Cortex Hormones; Adult; Age Factors; Aged; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil | 1974 |
Unusual reaction to chlorambucil in a patient with chronic lymphocytic leukemia.
Topics: Chlorambucil; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Leukemia, Lymphoid; Middle Aged | 1971 |
Multicentric reticulohistiocytosis. Report of a case with histochemical studies.
Topics: Adrenocorticotropic Hormone; Chlorambucil; Female; Hand; Histocytochemistry; Humans; Lipids; Lipopro | 1968 |
[Cryoglobulins, macroglobulins and the Gougerot-Sjogren syndrome. Treatment with chlorambucil and cyclophosphamide].
Topics: Arthritis; Biopsy; Blood Protein Disorders; Bone Marrow; Chlorambucil; Cryoglobulins; Cyclophosphami | 1974 |
Bullous pemphigoid in chronic lymphocytic leukemia with the demonstration of antibasement membrane antibodies.
Topics: Autoantibodies; Basement Membrane; Bilirubin; Biopsy; Blood Glucose; Blood Urea Nitrogen; Chlorambuc | 1974 |
Disseminated extrapulmonary nocardiosis presenting as a renal abscess.
Topics: Abscess; Adult; Anemia, Hemolytic, Autoimmune; Autopsy; Brain Diseases; Chlorambucil; Diagnosis, Dif | 1970 |
[Hair changes in immunosuppressive therapy].
Topics: Antineoplastic Agents; Azathioprine; Chlorambucil; Cyclophosphamide; Hair; Humans; Immunosuppression | 1971 |
[Lyell's syndrome observed during immunosuppressive treatment].
Topics: Adolescent; Chlorambucil; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Skin Diseases; St | 1968 |