chlorambucil has been researched along with DDD MPGNII in 7 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "There is a spectrum of types of MPGN seen in patients with CLL and there appears to be an association with the presence of monoclonal gammopathy." | 1.31 | Membranoproliferative glomerulonephritis in association with chronic lymphocytic leukaemia: a report of three cases. ( Dwyer, KM; Firkin, F; Hill, PA; Lee, P; Murphy, BF, 2002) |
| "Nephrotic syndrome was observed in nine patients." | 1.28 | Glomerulonephritis in chronic lymphocytic leukemia and related B-cell lymphomas. ( Fillastre, JP; Francois, A; Mignon, F; Mougenot, B; Moulin, B; Ronco, PM, 1992) |
| "The renal survival of 53 MPGN patients treated on a long-term basis by non-steroid anti-inflammatory drugs (NSAID) was compared to that of untreated MPGN patients previously reported in the literature." | 1.27 | Renal survival in membranoproliferative glomerulonephritis (MPGN): role of long-term treatment with non-steroid anti-inflammatory drugs (NSAID). ( Belghiti, D; Lagrue, G; Laurent, J, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bodaghi, E | 1 |
| Chamsa, AM | 1 |
| Ratner, MIa | 1 |
| Fedorova, ND | 1 |
| Biriukova, LS | 1 |
| Makurov, AI | 1 |
| Rajpoot, DK | 1 |
| Pahl, M | 1 |
| Clark, J | 1 |
| Hill, PA | 1 |
| Firkin, F | 1 |
| Dwyer, KM | 1 |
| Lee, P | 1 |
| Murphy, BF | 1 |
| Moulin, B | 1 |
| Ronco, PM | 1 |
| Mougenot, B | 1 |
| Francois, A | 1 |
| Fillastre, JP | 1 |
| Mignon, F | 1 |
| Klinger, M | 1 |
| Szewczyk, Z | 1 |
| Lagrue, G | 1 |
| Laurent, J | 1 |
| Belghiti, D | 1 |
1 trial available for chlorambucil and DDD MPGNII
| Article | Year |
|---|---|
[Programs of immunosuppressive and anti-inflammatory therapy of primary idiopathic glomerulonephritis. II. Membranous, membrano- proliferative and mesangial glomerulonephritis].
Topics: Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Drug Therapy | 1989 |
6 other studies available for chlorambucil and DDD MPGNII
| Article | Year |
|---|---|
[Primary nephrotic syndromes in children in Iran].
Topics: Adolescent; Anti-Inflammatory Agents; Biopsy; Child; Child, Preschool; Chlorambucil; Cyclophosphamid | 1978 |
[The therapy of mesangiocapillary glomerulonephritis].
Topics: Chlorambucil; Chronic Disease; Dipyridamole; Drug Evaluation; Drug Therapy, Combination; Glomerulone | 1995 |
Nephrotic syndrome associated with Kimura disease.
Topics: Adolescent; Angiolymphoid Hyperplasia with Eosinophilia; Anti-Inflammatory Agents; Antineoplastic Ag | 2000 |
Membranoproliferative glomerulonephritis in association with chronic lymphocytic leukaemia: a report of three cases.
Topics: Adult; Aged; Antineoplastic Agents; Chlorambucil; Drug Therapy, Combination; Female; Glomerular Mesa | 2002 |
Glomerulonephritis in chronic lymphocytic leukemia and related B-cell lymphomas.
Topics: Adult; Aged; Aged, 80 and over; B-Lymphocytes; Chlorambucil; Female; Glomerulonephritis; Glomerulone | 1992 |
Renal survival in membranoproliferative glomerulonephritis (MPGN): role of long-term treatment with non-steroid anti-inflammatory drugs (NSAID).
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Chlorambucil; Creati | 1988 |