chlorambucil has been researched along with Crohn Disease in 4 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Crohn Disease: A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The diagnosis of MALT lymphoma with adenoma on a background of Crohn's disease was made." | 2.61 | Synchronous colonic adenoma and intestinal marginal zone B-cell lymphoma associated with Crohn's disease: a case report and literature review. ( Achraf, M; Bennani, A; Imane, K; Kharrasse, G; Mohamed, B; Wafa, K; Zahi, I, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bennani, A | 1 |
| Kharrasse, G | 1 |
| Achraf, M | 1 |
| Wafa, K | 1 |
| Zahi, I | 1 |
| Imane, K | 1 |
| Mohamed, B | 1 |
| Mohácsi, G | 1 |
| Benkó, G | 1 |
| Mágori, A | 1 |
| György, A | 1 |
| Sonkodi, S | 1 |
| Delespesse, G | 1 |
| Kennes, B | 1 |
| Duchateau, J | 1 |
3 reviews available for chlorambucil and Crohn Disease
| Article | Year |
|---|---|
Synchronous colonic adenoma and intestinal marginal zone B-cell lymphoma associated with Crohn's disease: a case report and literature review.
Topics: Adenoma; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunological; Biopsy; Chlorambuc | 2019 |
[Auto-immune diseases and immunodepressive therapy. II. Current clinical indications].
Topics: Adrenal Cortex Hormones; Anemia, Hemolytic, Autoimmune; Antineoplastic Agents; Arteritis; Autoimmune | 1974 |
Cytotoxic drugs in treatment of nonmalignant diseases.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Arthritis, Rheumatoid; Azathioprine; Chlor | 1972 |
1 other study available for chlorambucil and Crohn Disease
| Article | Year |
|---|---|
[Polyarteritis nodosa based on a case report].
Topics: Adult; Appendectomy; Appendicitis; Appendix; Chlorambucil; Colitis, Ulcerative; Crohn Disease; Diagn | 1987 |