chlorambucil has been researched along with Congenital Limb Deformities in 2 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| " They type and frequency of malformations differed according to the dosage and day of treatment." | 1.25 | Teratogenic effects of chlorambucil on in vivo and in vitro organogenesis in mice. ( Kochhar, DM; Salder, TW, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Salder, TW | 1 |
| Kochhar, DM | 1 |
| Kernis, MM | 1 |
2 other studies available for chlorambucil and Congenital Limb Deformities
| Article | Year |
|---|---|
Teratogenic effects of chlorambucil on in vivo and in vitro organogenesis in mice.
Topics: Abnormalities, Drug-Induced; Animals; Cells, Cultured; Chlorambucil; Female; Fetus; Gestational Age; | 1975 |
Cysteine interference with chlorambucil-induced teratogenesis in the rat.
Topics: Abnormalities, Drug-Induced; Animals; Chlorambucil; Clubfoot; Cysteine; Drug Antagonism; Ectromelia; | 1972 |