chlorambucil has been researched along with Chromosomal Translocation in 10 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The biology of follicular lymphoma evidently includes the potential for tumor dormancy after therapies with varied mechanisms of action, resulting in clinical inactivity for many years." | 2.69 | Anti-idiotype antibodies can induce long-term complete remissions in non-Hodgkin's lymphoma without eradicating the malignant clone. ( Czerwinski, DK; Davis, TA; Levy, R; Liles, TM; Maloney, DG, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Funasaki, S | 1 |
| Mehanna, S | 1 |
| Ma, W | 1 |
| Nishizawa, H | 1 |
| Kamikubo, Y | 1 |
| Sugiyama, H | 1 |
| Ikeda, S | 1 |
| Motoshima, T | 1 |
| Hasumi, H | 1 |
| Linehan, WM | 1 |
| Schmidt, LS | 1 |
| Ricketts, C | 1 |
| Suda, T | 1 |
| Oike, Y | 1 |
| Kamba, T | 1 |
| Baba, M | 1 |
| Lévy, M | 3 |
| Dupuis, J | 2 |
| Charpy, C | 1 |
| Martin, A | 1 |
| Itti, E | 1 |
| Sobhani, I | 3 |
| Haioun, C | 3 |
| Amiot, A | 2 |
| Copie-Bergman, C | 2 |
| Molinier-Frenkel, V | 1 |
| Riou, A | 1 |
| Gaulard, P | 1 |
| Delfau-Larue, MH | 2 |
| Leroy, K | 2 |
| Delchier, JC | 2 |
| Le Baleur, Y | 1 |
| Belhadj, K | 1 |
| Hémery, F | 1 |
| Robak, E | 1 |
| Jesionek-Kupnicka, D | 1 |
| Robak, T | 1 |
| Holub, A | 1 |
| Wawrzyniak, E | 1 |
| Bartkowiak, J | 1 |
| Bednarek, A | 1 |
| Constantinu, M | 1 |
| Urbanska-Rys, H | 1 |
| Hirt, C | 1 |
| Schüler, F | 1 |
| Kiefer, T | 1 |
| Schwenke, C | 1 |
| Haas, A | 1 |
| Niederwieser, D | 1 |
| Neser, S | 1 |
| Assmann, M | 1 |
| Srock, S | 1 |
| Rohrberg, R | 1 |
| Dachselt, K | 1 |
| Leithäuser, M | 1 |
| Rabkin, CS | 1 |
| Herold, M | 1 |
| Dölken, G | 1 |
| Generoso, WM | 1 |
| Witt, KL | 1 |
| Cain, KT | 1 |
| Hughes, L | 1 |
| Cacheiro, NL | 1 |
| Lockhart, AM | 1 |
| Shelby, MD | 1 |
| Davis, TA | 1 |
| Maloney, DG | 1 |
| Czerwinski, DK | 1 |
| Liles, TM | 1 |
| Levy, R | 1 |
| Westin, J | 1 |
| Montero, S | 1 |
| Caballín, MR | 1 |
| Coll, MD | 1 |
| Besses, C | 1 |
| Woessner, S | 1 |
| Egozcue, J | 1 |
| Solé, F | 1 |
3 trials available for chlorambucil and Chromosomal Translocation
| Article | Year |
|---|---|
Treatment of t(11;18)-positive gastric mucosa-associated lymphoid tissue lymphoma with rituximab and chlorambucil: clinical, histological, and molecular follow-up.
Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined | 2010 |
Rapid and sustained clearance of circulating lymphoma cells after chemotherapy plus rituximab: clinical significance of quantitative t(14;18) PCR monitoring in advanced stage follicular lymphoma patients.
Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined | 2008 |
Anti-idiotype antibodies can induce long-term complete remissions in non-Hodgkin's lymphoma without eradicating the malignant clone.
Topics: Animals; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Antibodies, Neoplasm; Antineoplastic Ag | 1998 |
7 other studies available for chlorambucil and Chromosomal Translocation
| Article | Year |
|---|---|
Targeting chemoresistance in Xp11.2 translocation renal cell carcinoma using a novel polyamide-chlorambucil conjugate.
Topics: Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Carcinoma, Renal Cell; Chlorambucil; Ch | 2022 |
Rituximab or rituximab plus chlorambucil for translocation (11;18)-negative gastric mucosa-associated lymphoid tissue lymphoma: a monocentric non-randomized observational study.
Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Case-Control | 2022 |
Rituximab and chlorambucil versus rituximab alone in gastric mucosa-associated lymphoid tissue lymphoma according to t(11;18) status: a monocentric non-randomized observational study.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chem | 2013 |
Primary cutaneous marginal zone B-cell lymphoma in a patient with chronic lymphocytic leukaemia.
Topics: Aged, 80 and over; Antineoplastic Agents, Alkylating; Chlorambucil; Chromosome Deletion; Chromosomes | 2007 |
Dominant lethal and heritable translocation tests with chlorambucil and melphalan in male mice.
Topics: Animals; Antineoplastic Agents, Alkylating; Chlorambucil; Female; Genes, Dominant; Genes, Lethal; Ge | 1995 |
Chromosome abnormalities after chlorambucil therapy of polycythaemia vera.
Topics: Aged; Bone Marrow; Bone Marrow Cells; Chlorambucil; Chromosome Aberrations; Chromosome Deletion; Fem | 1976 |
New chromosomal abnormality. t(1;19;?) in a case of B-chronic lymphocytic leukemia.
Topics: Aged; Aged, 80 and over; Chlorambucil; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 19; Fema | 1992 |