Page last updated: 2024-10-24

chlorambucil and Chromosomal Breakage

chlorambucil has been researched along with Chromosomal Breakage in 1 studies

Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Efthimiou, M1
Stephanou, G1
Demopoulos, NA1
Nikolaropoulos, SS1

Other Studies

1 other study available for chlorambucil and Chromosomal Breakage

ArticleYear
Aneugenic potential of the anticancer drugs melphalan and chlorambucil. The involvement of apoptosis and chromosome segregation regulating proteins.
    Journal of applied toxicology : JAT, 2013, Volume: 33, Issue:7

    Topics: Amino Acid Chloromethyl Ketones; Animals; Annexin A5; Antineoplastic Agents, Alkylating; Apoptosis;

2013