chlorambucil has been researched along with Cerebellar Ataxia in 1 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Cerebellar Ataxia: Incoordination of voluntary movements that occur as a manifestation of CEREBELLAR DISEASES. Characteristic features include a tendency for limb movements to overshoot or undershoot a target (dysmetria), a tremor that occurs during attempted movements (intention TREMOR), impaired force and rhythm of diadochokinesis (rapidly alternating movements), and GAIT ATAXIA. (From Adams et al., Principles of Neurology, 6th ed, p90)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ataxia in macroglobulinemia has been attributed to cerebral infarction and blood hyperviscosity, but no previous case reports documented gradually progressive cerebellar signs without these concomitants and with regression on therapy." | 1.26 | Progressive and treatable cerebellar ataxia in macroglobulinemia. ( Moench, JC; Spencer, SS, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Spencer, SS | 1 |
| Moench, JC | 1 |
1 other study available for chlorambucil and Cerebellar Ataxia
| Article | Year |
|---|---|
Progressive and treatable cerebellar ataxia in macroglobulinemia.
Topics: Cerebellar Ataxia; Chlorambucil; Humans; Male; Middle Aged; Waldenstrom Macroglobulinemia | 1980 |