chlorambucil has been researched along with Central Nervous System Diseases in 2 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Central Nervous System Diseases: Diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chlorambucil (CHL) was used in combination with prednisolone in the treatment of nine children with frequently relapsing nephrotic syndrome." | 7.67 | Chlorambucil central nervous toxicity: a significant side effect of chlorambucil therapy in childhood nephrotic syndrome. ( Asada, R; Ichida, F; Konda, M; Konishi, T; Kyotani, S; Okada, T; Suzuki, Y; Tani, M; Tanizawa, T; Yamatani, M, 1985) |
| "Chlorambucil (CHL) was used in combination with prednisolone in the treatment of nine children with frequently relapsing nephrotic syndrome." | 3.67 | Chlorambucil central nervous toxicity: a significant side effect of chlorambucil therapy in childhood nephrotic syndrome. ( Asada, R; Ichida, F; Konda, M; Konishi, T; Kyotani, S; Okada, T; Suzuki, Y; Tani, M; Tanizawa, T; Yamatani, M, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pivetti Pezzi, P | 1 |
| Gasparri, V | 1 |
| De Liso, P | 1 |
| Catarinelli, G | 1 |
| Ichida, F | 1 |
| Konishi, T | 1 |
| Asada, R | 1 |
| Yamatani, M | 1 |
| Konda, M | 1 |
| Tani, M | 1 |
| Tanizawa, T | 1 |
| Suzuki, Y | 1 |
| Okada, T | 1 |
| Kyotani, S | 1 |
2 other studies available for chlorambucil and Central Nervous System Diseases
| Article | Year |
|---|---|
Prognosis in Behcet's disease.
Topics: Adolescent; Adult; Behcet Syndrome; Central Nervous System Diseases; Chlorambucil; Eye Diseases; Fem | 1985 |
Chlorambucil central nervous toxicity: a significant side effect of chlorambucil therapy in childhood nephrotic syndrome.
Topics: Brain; Central Nervous System Diseases; Child; Chlorambucil; Drug Therapy, Combination; Electroencep | 1985 |