chlorambucil has been researched along with Cell Transformation, Viral in 2 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Cell Transformation, Viral: An inheritable change in cells manifested by changes in cell division and growth and alterations in cell surface properties. It is induced by infection with a transforming virus.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In melphalan-treated patients where LCLs were established serially, the melphalan Do increased after further melphalan treatment in vivo and decreased when no further treatment was given." | 1.27 | Melphalan-resistant lymphoblastoid cell lines established from patients with ovarian cancer treated with cross-linking agents. ( Daunter, B; Khoo, SK; Maynard, K; Musk, P; Parsons, PG, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ghose, T | 1 |
| Lee, CL | 1 |
| Faulkner, G | 1 |
| Fernandez, LA | 1 |
| Lee, SH | 1 |
| Maynard, K | 1 |
| Musk, P | 1 |
| Daunter, B | 1 |
| Khoo, SK | 1 |
| Parsons, PG | 1 |
2 other studies available for chlorambucil and Cell Transformation, Viral
| Article | Year |
|---|---|
Progression of a human B cell chronic lymphocytic leukemia line in nude mice.
Topics: Animals; B-Lymphocytes; Cell Division; Cell Transformation, Viral; Chlorambucil; Chronic Disease; Fr | 1988 |
Melphalan-resistant lymphoblastoid cell lines established from patients with ovarian cancer treated with cross-linking agents.
Topics: B-Lymphocytes; Cell Line; Cell Survival; Cell Transformation, Viral; Cells, Cultured; Chlorambucil; | 1985 |