chlorambucil has been researched along with Cataract in 4 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A mouse mutant expressing a bilateral nuclear and radial cataract was found after paternal treatment with chlorambucil." | 3.71 | A 6-bp deletion in the Crygc gene leading to a nuclear and radial cataract in the mouse. ( Favor, J; Graw, J; Löster, J; Neuhäuser-Klaus, A, 2002) |
| "Chlorambucil therapy was begun at 2 mg daily, increased by 2 mg per day each week to the maximum of 8 to 12 mg per day." | 1.29 | Chlorambucil therapy in sympathetic ophthalmia. ( Liu, JH; Yang, CS, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, CS | 1 |
| Liu, JH | 1 |
| Graw, J | 1 |
| Neuhäuser-Klaus, A | 1 |
| Löster, J | 1 |
| Favor, J | 1 |
| Goldschmidt, E | 1 |
| Lochte, J | 1 |
| Rugh, R | 1 |
4 other studies available for chlorambucil and Cataract
| Article | Year |
|---|---|
Chlorambucil therapy in sympathetic ophthalmia.
Topics: Adult; Cataract; Cataract Extraction; Chlorambucil; Eye Foreign Bodies; Eye Injuries, Penetrating; F | 1995 |
A 6-bp deletion in the Crygc gene leading to a nuclear and radial cataract in the mouse.
Topics: Alleles; Animals; Antineoplastic Agents, Alkylating; Base Sequence; Cataract; Chlorambucil; Chromoso | 2002 |
Treatment of a case of sympathetic ophthalmia.
Topics: Acetates; Anti-Inflammatory Agents; Antilymphocyte Serum; Azathioprine; Cataract; Child; Chlorambuci | 1974 |
Radiobiology. NYO-2740-4.
Topics: Animals; Animals, Newborn; Cataract; Chlorambucil; Embryo, Mammalian; Female; Fetus; Haplorhini; Hum | 1967 |