chlorambucil has been researched along with Cataract, Membranous in 4 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A mouse mutant expressing a bilateral nuclear and radial cataract was found after paternal treatment with chlorambucil." | 3.71 | A 6-bp deletion in the Crygc gene leading to a nuclear and radial cataract in the mouse. ( Favor, J; Graw, J; Löster, J; Neuhäuser-Klaus, A, 2002) |
| "Chlorambucil therapy was begun at 2 mg daily, increased by 2 mg per day each week to the maximum of 8 to 12 mg per day." | 1.29 | Chlorambucil therapy in sympathetic ophthalmia. ( Liu, JH; Yang, CS, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, CS | 1 |
| Liu, JH | 1 |
| Graw, J | 1 |
| Neuhäuser-Klaus, A | 1 |
| Löster, J | 1 |
| Favor, J | 1 |
| Goldschmidt, E | 1 |
| Lochte, J | 1 |
| Rugh, R | 1 |
4 other studies available for chlorambucil and Cataract, Membranous
| Article | Year |
|---|---|
Chlorambucil therapy in sympathetic ophthalmia.
Topics: Adult; Cataract; Cataract Extraction; Chlorambucil; Eye Foreign Bodies; Eye Injuries, Penetrating; F | 1995 |
A 6-bp deletion in the Crygc gene leading to a nuclear and radial cataract in the mouse.
Topics: Alleles; Animals; Antineoplastic Agents, Alkylating; Base Sequence; Cataract; Chlorambucil; Chromoso | 2002 |
Treatment of a case of sympathetic ophthalmia.
Topics: Acetates; Anti-Inflammatory Agents; Antilymphocyte Serum; Azathioprine; Cataract; Child; Chlorambuci | 1974 |
Radiobiology. NYO-2740-4.
Topics: Animals; Animals, Newborn; Cataract; Chlorambucil; Embryo, Mammalian; Female; Fetus; Haplorhini; Hum | 1967 |