chlorambucil has been researched along with Cat Diseases in 12 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Cat Diseases: Diseases of the domestic cat (Felis catus or F. domesticus). This term does not include diseases of the so-called big cats such as CHEETAHS; LIONS; tigers, cougars, panthers, leopards, and other Felidae for which the heading CARNIVORA is used.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aims of this study were to evaluate the response, outcome and prognostic factors in cats with clinically presumed relapsed low-grade alimentary lymphoma (LGAL) receiving cyclophosphamide as a first-line rescue therapy after failing chlorambucil treatment." | 8.02 | Cyclophosphamide rescue therapy for relapsed low-grade alimentary lymphoma after chlorambucil treatment in cats. ( Borrego, J; Chon, E; Kim, C; Wouda, RM, 2021) |
| "The aims of this study were to evaluate the response, outcome and prognostic factors in cats with clinically presumed relapsed low-grade alimentary lymphoma (LGAL) receiving cyclophosphamide as a first-line rescue therapy after failing chlorambucil treatment." | 4.02 | Cyclophosphamide rescue therapy for relapsed low-grade alimentary lymphoma after chlorambucil treatment in cats. ( Borrego, J; Chon, E; Kim, C; Wouda, RM, 2021) |
| "Chlorambucil treatment was continued every other day and a single, variably timed sample collection was obtained on day 14." | 1.72 | Population pharmacokinetics identifies rapid gastrointestinal absorption and plasma clearance of oral chlorambucil administered to cats with indolent lymphoproliferative malignancies. ( Al-Nadaf, S; Burton, JH; Skorupski, KA; Wittenburg, LA, 2022) |
| "Treatment with chlorambucil and corticosteroids was started at standard doses, based on published protocols." | 1.43 | Acquired Fanconi syndrome in four cats treated with chlorambucil. ( Feldman, DG; Reinert, NC, 2016) |
| "Patients with intestinal small cell lymphosarcoma can present identical clinical signs, and differentiating between these two conditions can be a challenge." | 1.39 | Feline small cell lymphosarcoma versus inflammatory bowel disease: treatment and prognosis. ( Al-Ghazlat, S; de Rezende, CE, 2013) |
| "Most cats with lymphocytic lymphoma responded to treatment with prednisone and chlorambucil, and most factors evaluated were not associated with outcome." | 1.35 | Outcome of cats with low-grade lymphocytic lymphoma: 41 cases (1995-2005). ( Erb, HN; Goldstein, RE; Kiselow, MA; McDonough, SP; Rassnick, KM; Simpson, KW; Weinkle, TK, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 4 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Viviano, KR | 1 |
| Wootton, F | 1 |
| Glanemann, B | 1 |
| Langley-Hobbs, S | 1 |
| Breheny, C | 1 |
| Fowlie, S | 1 |
| Whitworth, F | 1 |
| Silvestrini, P | 1 |
| Threlfall, A | 1 |
| Sorrell, S | 1 |
| Black, V | 1 |
| Al-Nadaf, S | 1 |
| Wittenburg, LA | 1 |
| Skorupski, KA | 1 |
| Burton, JH | 1 |
| Kim, C | 1 |
| Wouda, RM | 1 |
| Borrego, J | 1 |
| Chon, E | 1 |
| de Rezende, CE | 1 |
| Al-Ghazlat, S | 1 |
| Reinert, NC | 1 |
| Feldman, DG | 1 |
| Peterson, A | 1 |
| McKay, L | 1 |
| Irwin, KE | 1 |
| Beale, KM | 1 |
| Fadok, VA | 1 |
| Kiselow, MA | 1 |
| Rassnick, KM | 1 |
| McDonough, SP | 1 |
| Goldstein, RE | 1 |
| Simpson, KW | 1 |
| Weinkle, TK | 1 |
| Erb, HN | 1 |
| Miller, E | 1 |
| Mundell, AC | 1 |
| Brick, JO | 1 |
| Roenigk, WJ | 1 |
| Wilson, GP | 1 |
4 reviews available for chlorambucil and Cat Diseases
| Article | Year |
|---|---|
Glucocorticoids, Cyclosporine, Azathioprine, Chlorambucil, and Mycophenolate in Dogs and Cats: Clinical Uses, Pharmacology, and Side Effects.
Topics: Animals; Azathioprine; Cat Diseases; Cats; Chlorambucil; Cyclosporine; Dog Diseases; Dogs; Drug-Rela | 2022 |
Crusty cats: feline pemphigus foliaceus.
Topics: Animals; Cat Diseases; Cats; Chlorambucil; Cyclosporine; Immunosuppressive Agents; Pemphigus | 2010 |
The use of cytotoxic agents in the treatment of immune-mediated diseases of dogs and cats.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Azathioprine; Cat Disea | 1997 |
New therapeutic agents in veterinary dermatology.
Topics: 4-Quinolones; Animals; Anti-Infective Agents; Cat Diseases; Cats; Chlorambucil; Clofazimine; Dog Dis | 1990 |
8 other studies available for chlorambucil and Cat Diseases
| Article | Year |
|---|---|
Feline non-erosive immune-mediated polyarthritis: a multicentre, retrospective study of 20 cases (2009-2020).
Topics: Animals; Arthritis; Cat Diseases; Cats; Chlorambucil; Cyclosporine; Female; Fever; Immunosuppressive | 2022 |
Population pharmacokinetics identifies rapid gastrointestinal absorption and plasma clearance of oral chlorambucil administered to cats with indolent lymphoproliferative malignancies.
Topics: Administration, Oral; Animals; Area Under Curve; Cat Diseases; Cats; Chlorambucil; Gastrointestinal | 2022 |
Cyclophosphamide rescue therapy for relapsed low-grade alimentary lymphoma after chlorambucil treatment in cats.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cat Diseases; Cats; Chlorambucil; Cyclophos | 2021 |
Feline small cell lymphosarcoma versus inflammatory bowel disease: treatment and prognosis.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Cat Diseases; Cats; Chlorambucil; Diet; Gastr | 2013 |
Acquired Fanconi syndrome in four cats treated with chlorambucil.
Topics: Animals; Antineoplastic Agents, Alkylating; Cat Diseases; Cats; Chlorambucil; Diagnosis, Differentia | 2016 |
Use of modified ciclosporin in the management of feline pemphigus foliaceus: a retrospective analysis.
Topics: Animals; Cat Diseases; Cats; Chlorambucil; Cyclosporine; Dose-Response Relationship, Drug; Female; G | 2012 |
Outcome of cats with low-grade lymphocytic lymphoma: 41 cases (1995-2005).
Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Cat Diseases; Cats; Chl | 2008 |
Chemotherapy of malignant lymphoma in dogs and cats.
Topics: Animals; Blood Cells; Cat Diseases; Cats; Chlorambucil; Cyclophosphamide; Dog Diseases; Dogs; Female | 1968 |