chlorambucil has been researched along with Castleman Disease in 4 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Castleman Disease: Large benign, hyperplastic lymph nodes. The more common hyaline vascular subtype is characterized by small hyaline vascular follicles and interfollicular capillary proliferations. Plasma cells are often present and represent another subtype with the plasma cells containing IgM and IMMUNOGLOBULIN A.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Castleman disease is a rare cause of lymphoid hyperplasia and may result in localized symptoms or an aggressive, multisystem disorder." | 1.48 | Sjögren's and plasma cell variant Castleman disease: a case report. ( Abrahams, AD; Dei-Adomakoh, YA; Dey, DI; Quarcoopome, L; Segbefia, CI, 2018) |
| "Multicentric Castleman's disease (MCD), or multicentric angiofollicular lymph node hyperplasia, is an uncommon lymphoproliferative disorder which typically present with constitutional symptoms, multicentric lymphadenopathy, hepatosplenomegaly, effusions, and ascites." | 1.29 | Presentation of multicentric Castleman's disease with sicca syndrome, cardiomyopathy, palmar and plantar rash. ( Cripe, LD; Hall, BD; Kingsmore, SF; Sheldon, EA; Silva, OE; St Clair, EW, 1993) |
| "A case of angiofollicular lymph node hyperplasia of plasma cell type in a 60-year-old woman is reported." | 1.28 | A successfully treated case of multicentric angiofollicular hyperplasia with oral chemotherapy (Castleman's disease). ( Bai, MC; Bourantas, CL; Pavlidis, NA; Skopouli, FN, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dei-Adomakoh, YA | 1 |
| Quarcoopome, L | 1 |
| Abrahams, AD | 1 |
| Segbefia, CI | 1 |
| Dey, DI | 1 |
| Senanayake, S | 1 |
| Kelly, J | 1 |
| Lloyd, A | 1 |
| Waliuzzaman, Z | 1 |
| Goldstein, D | 1 |
| Rawlinson, W | 1 |
| Kingsmore, SF | 1 |
| Silva, OE | 1 |
| Hall, BD | 1 |
| Sheldon, EA | 1 |
| Cripe, LD | 1 |
| St Clair, EW | 1 |
| Pavlidis, NA | 1 |
| Skopouli, FN | 1 |
| Bai, MC | 1 |
| Bourantas, CL | 1 |
4 other studies available for chlorambucil and Castleman Disease
| Article | Year |
|---|---|
Sjögren's and plasma cell variant Castleman disease: a case report.
Topics: Adult; Anemia, Hemolytic; Castleman Disease; Chlorambucil; Diagnosis, Differential; Drug Therapy, Co | 2018 |
Multicentric Castleman's disease treated with antivirals and immunosuppressants.
Topics: Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Antiviral Agents; Castleman Disea | 2003 |
Presentation of multicentric Castleman's disease with sicca syndrome, cardiomyopathy, palmar and plantar rash.
Topics: Adult; Cardiomyopathies; Castleman Disease; Chlorambucil; Female; Foot; Hand; Humans; Prednisone; Sj | 1993 |
A successfully treated case of multicentric angiofollicular hyperplasia with oral chemotherapy (Castleman's disease).
Topics: Antineoplastic Combined Chemotherapy Protocols; Castleman Disease; Chlorambucil; Female; Humans; Mid | 1990 |