chlorambucil has been researched along with Cardiac Output, Low in 1 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Cardiac Output, Low: A state of subnormal or depressed cardiac output at rest or during stress. It is a characteristic of CARDIOVASCULAR DISEASES, including congenital, valvular, rheumatic, hypertensive, coronary, and cardiomyopathic. The serious form of low cardiac output is characterized by marked reduction in STROKE VOLUME, and systemic vasoconstriction resulting in cold, pale, and sometimes cyanotic extremities.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bleeding tendency was seen in 17%, infections in 17%, hyperviscosity syndrome in 12%, and cardiac failure in 25% of the patients." | 1.31 | Waldenström's macroglobulinemia: clinical course and prognostic factors in 60 patients. Experience from a single hematology unit. ( Angelopoulou, MK; Boussiotis, V; Dimopoulou, MN; Fessas, P; Gribabis, A; Kittas, C; Konstantopoulos, K; Kontopidou, FN; Kyrtsonis, MC; Pangalis, GA; Siakantaris, P; Vaiopoulos, GA; Vassilakopoulos, TP, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kyrtsonis, MC | 1 |
| Vassilakopoulos, TP | 1 |
| Angelopoulou, MK | 1 |
| Siakantaris, P | 1 |
| Kontopidou, FN | 1 |
| Dimopoulou, MN | 1 |
| Boussiotis, V | 1 |
| Gribabis, A | 1 |
| Konstantopoulos, K | 1 |
| Vaiopoulos, GA | 1 |
| Fessas, P | 1 |
| Kittas, C | 1 |
| Pangalis, GA | 1 |
1 other study available for chlorambucil and Cardiac Output, Low
| Article | Year |
|---|---|
Waldenström's macroglobulinemia: clinical course and prognostic factors in 60 patients. Experience from a single hematology unit.
Topics: Adult; Aged; Aged, 80 and over; Blood Viscosity; Cardiac Output, Low; Chlorambucil; Fatigue; Female; | 2001 |