chlorambucil has been researched along with Carcinoma, Epidermoid in 20 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the absence of evidence of a dose-response curve for platinum, the lower dosage schedules that can be used with acceptable toxicity on an outpatient basis should be selected." | 3.75 | Chemotherapy for squamous cell carcinoma of the head and neck: a progress report. ( Glick, JH; Taylor, SG; Zehngebot, LM, 1980) |
| "Chlorambucil was linked to prednisolone to improve the therapeutic and toxic properties of this potent alkylating agent, which is known to induce second tumors in humans." | 1.27 | Long-term toxicology effects of prednimustine in comparison with chlorambucil, prednisolone, and chlorambucil plus prednisolone in Sprague-Dawley rats. ( Berger, MR; Habs, M; Schmähl, D, 1986) |
| " Eleven patients with advanced carcinoma of the lung (5 adenocarcinoma, 3 squamous cell carcinoma, 2 small cell carcinoma and 1 large cell carcinoma) were treated at a dosage of 40 mg." | 1.26 | Preliminary clinical study of prednimustine in lung cancer. ( Catane, H; Catane, R; Kaufman, JH; Mittelman, A; Murphy, GP; Takita, H, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (90.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Streu, E | 1 |
| HORWITZ, H | 1 |
| WRIGHT, TL | 1 |
| PERRY, H | 1 |
| BARRETT, CM | 1 |
| Glick, JH | 1 |
| Zehngebot, LM | 1 |
| Taylor, SG | 1 |
| Savage, PE | 1 |
| Carmody, RG | 1 |
| Highman, JH | 1 |
| Catane, H | 1 |
| Catane, R | 1 |
| Takita, H | 1 |
| Kaufman, JH | 1 |
| Mittelman, A | 1 |
| Murphy, GP | 1 |
| Haefliger, JM | 1 |
| Alberto, P | 1 |
| Hill, BH | 1 |
| Chauvergne, J | 1 |
| Rohart, J | 1 |
| Héron, JF | 1 |
| Aymé, Y | 1 |
| Berlié, J | 1 |
| Fargeot, P | 1 |
| George, M | 1 |
| Lebrun-Jezekova, D | 1 |
| Pigneux, J | 1 |
| Chenal, C | 1 |
| Berger, MR | 1 |
| Habs, M | 1 |
| Schmähl, D | 1 |
| Baumgartner, G | 1 |
| Rathert, P | 1 |
| Terhorst, B | 1 |
| Lutzeyer, W | 1 |
| Sugiura, K | 1 |
| Hoerni, B | 1 |
| Brunet, R | 1 |
| Hoerni-Simon, G | 1 |
| Armstrong, JG | 1 |
| Le Goff, P | 1 |
| Le Menn, G | 1 |
| Nechaeva, ID | 1 |
| Kotova, DG | 1 |
| Livshits, MA | 1 |
| Lleander, VC | 1 |
| Goldstein, G | 1 |
| Horsley, JS | 1 |
| Renner, K | 1 |
| Green, RA | 1 |
| Humphrey, E | 1 |
| Close, H | 1 |
| Patno, ME | 1 |
2 reviews available for chlorambucil and Carcinoma, Epidermoid
| Article | Year |
|---|---|
Chemotherapy for squamous cell carcinoma of the head and neck: a progress report.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil; Clinical Trials as Topic; | 1980 |
[Randomized trial of initial chemotherapy in 151 locally advanced carcinoma of the cervix (T2b-N1, T3b, MO)].
Topics: Actuarial Analysis; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; | 1990 |
3 trials available for chlorambucil and Carcinoma, Epidermoid
| Article | Year |
|---|---|
Chemotherapy for squamous cell carcinoma of the head and neck: a progress report.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil; Clinical Trials as Topic; | 1980 |
[Randomized trial of initial chemotherapy in 151 locally advanced carcinoma of the cervix (T2b-N1, T3b, MO)].
Topics: Actuarial Analysis; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; | 1990 |
Alkylating agents in bronchogenic carcinoma.
Topics: Adenocarcinoma; Alkylating Agents; Carcinoma; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Chl | 1969 |
17 other studies available for chlorambucil and Carcinoma, Epidermoid
| Article | Year |
|---|---|
Second malignancies in chronic lymphocytic leukemia.
Topics: Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Carcin | 2014 |
"SUPPRESSIVE" CHEMOTHERAPY IN BRONCHOGENIC CARCINOMA: A RANDOMIZED PROSPECTIVE CLINICAL TRIAL.
Topics: Adenocarcinoma; Biomedical Research; Carcinoma; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; C | 1965 |
Evaluation of gallium-67 in the diagnosis of bronchial carcinoma.
Topics: Adenocarcinoma; Bronchial Neoplasms; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Chlorambucil; | 1976 |
Preliminary clinical study of prednimustine in lung cancer.
Topics: Adenocarcinoma; Aged; Carcinoma; Carcinoma, Squamous Cell; Chlorambucil; Female; Humans; Lung Neopla | 1977 |
[Retrospective study of 99 cases of ovarian carcinoma, stages I to IV].
Topics: Aged; Carcinoma, Squamous Cell; Chlorambucil; Cyclophosphamide; Female; Humans; Middle Aged; Neoplas | 1977 |
Immunosuppressive drug therapy as a potentiator of skin tumours in five patients with lymphoma.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Chlorambucil; H | 1976 |
Long-term toxicology effects of prednimustine in comparison with chlorambucil, prednisolone, and chlorambucil plus prednisolone in Sprague-Dawley rats.
Topics: Animals; Carcinoma, Squamous Cell; Chlorambucil; Drug Therapy, Combination; Ear Neoplasms; Female; M | 1986 |
[Results with the cytostatic agent bleomycin in tumour therapy (author's transl)].
Topics: Adult; Aged; Bleomycin; Bronchial Neoplasms; Carcinoma, Squamous Cell; Chlorambucil; Doxorubicin; Dr | 1973 |
[Bleomycin for malignant tumours of the genitals of the male (author's transl)].
Topics: Adrenal Cortex Hormones; Adult; Age Factors; Aged; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil | 1974 |
Chemotherapy of induced skin tumors in mice.
Topics: Alkylating Agents; Animals; Antimetabolites; Antineoplastic Agents; Benz(a)Anthracenes; Busulfan; Ca | 1968 |
[Richter's syndrome. 4 cases and an attempt at analysis].
Topics: Aged; Carcinoma, Squamous Cell; Chlorambucil; Cyclophosphamide; Deglutition Disorders; Drug Therapy, | 1973 |
Current problems in the use of the oncolytic drugs.
Topics: Antineoplastic Agents; Busulfan; Carcinoma, Squamous Cell; Child; Chlorambucil; Choriocarcinoma; Dac | 1968 |
[Cancer and immunosuppressive treatment. Apropos of 2 cases].
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Brain Neoplasms; Carcinoma, Squamous Cell; Chlorambucil; | 1974 |
Tumor conference.
Topics: Adult; Carcinoma, Squamous Cell; Chlorambucil; Female; Humans; Neoplasm Metastasis; Ovarian Neoplasm | 1968 |
[Evaluation of the role of chemotherapy following radical surgery for cilioepithelial tumors of the ovaries].
Topics: Adult; Antineoplastic Agents; Carcinoma, Squamous Cell; Chlorambucil; Cyclophosphamide; Female; Huma | 1972 |
Chemotherapy in the management of metastatic cancer of unknown primary site.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Carcinoma; Carcinoma, Squamous Cell; Chlorambucil; Cyclopho | 1972 |
[New formation of malignant tumors during cytostatic therapy. Case report].
Topics: Adenocarcinoma; Adrenal Cortex Hormones; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Chlo | 1971 |