chlorambucil has been researched along with Cancer of Spleen in 8 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Disease progression was significantly more frequent in patients presenting an immunological event or an M component." | 2.41 | Treatment of splenic marginal zone B-cell lymphoma: an analysis of 81 patients. ( Arcache, J; Arnaud, P; Berger, F; Callet-Bauchu, E; Coiffier, B; Dumontet, C; Felman, P; Hequet, O; Salles, G; Thieblemont, C, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thieblemont, C | 1 |
| Felman, P | 1 |
| Berger, F | 1 |
| Dumontet, C | 1 |
| Arnaud, P | 1 |
| Hequet, O | 1 |
| Arcache, J | 1 |
| Callet-Bauchu, E | 1 |
| Salles, G | 1 |
| Coiffier, B | 1 |
| Johnson, SA | 1 |
| Owen, RG | 1 |
| Oscier, DG | 1 |
| Leblond, V | 1 |
| Levy, V | 1 |
| Jaeger, U | 1 |
| Seymour, JF | 1 |
| Strickland, P | 1 |
| Lefrère, F | 1 |
| Hermine, O | 1 |
| Belanger, C | 1 |
| François, S | 1 |
| Tilly, H | 1 |
| Lebas de La Cour, JC | 1 |
| Valensi, F | 1 |
| Varet, B | 1 |
| Troussard, X | 1 |
| Mulligan, SP | 1 |
| Matutes, E | 1 |
| Dearden, C | 1 |
| Catovsky, D | 1 |
| Schmidt, CG | 1 |
| Auger, C | 1 |
| Berceanu, S | 1 |
| Sighetea, E | 1 |
| Gociu, M | 1 |
| Ghetie, I | 1 |
| Stoica, GH | 1 |
| Voiosu, R | 1 |
1 review available for chlorambucil and Cancer of Spleen
| Article | Year |
|---|---|
Treatment of splenic marginal zone B-cell lymphoma: an analysis of 81 patients.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Combin | 2002 |
2 trials available for chlorambucil and Cancer of Spleen
| Article | Year |
|---|---|
Phase III study of chlorambucil versus fludarabine as initial therapy for Waldenstrom's macroglobulinemia and related disorders.
Topics: Administration, Oral; Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Antineoplastic Ag | 2005 |
Radiotherapy or chemotherapy as the initial treatment for stage IIIA Hodgkin's disease (Report no 13).
Topics: Chlorambucil; Drug Therapy, Combination; Hodgkin Disease; Humans; Laparotomy; Mechlorethamine; Neopl | 1981 |
5 other studies available for chlorambucil and Cancer of Spleen
| Article | Year |
|---|---|
Fludarabine: an effective treatment in patients with splenic lymphoma with villous lymphocytes.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Comb | 2000 |
Splenic lymphoma with villous lymphocytes: natural history and response to therapy in 50 cases.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combin | 1991 |
[Clinical manifestation and chemotherapy in Hodgkin's disease].
Topics: Chlorambucil; Cyclophosphamide; Hodgkin Disease; Humans; Laparotomy; Methods; Methotrexate; Predniso | 1972 |
[Splenic form of lymphoid cryptoleukosis. (Apropos of a case. Observation and comments].
Topics: Aged; Chlorambucil; Female; Humans; Leukemia, Lymphoid; Radiography; Splenic Neoplasms | 1973 |
Peculiar forms of monoclonal gammapathies.
Topics: Adrenal Cortex Hormones; Antigen-Antibody Complex; Blood Protein Disorders; Chlorambucil; Cryoglobul | 1973 |