chlorambucil has been researched along with Cancer of Ovary in 135 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Three hundred and sixty-nine patients with advanced ovarian adenocarcinoma were treated in a prospective randomized trial comparing combination versus sequential therapy with chlorambucil and cisplatin." | 9.06 | Chemotherapy of advanced ovarian adenocarcinoma: a randomized comparison of combination versus sequential therapy using chlorambucil and cisplatin. ( , 1986) |
| "Fifty-six tumor specimens from patients with ovarian adenocarcinoma were tested for sensitivity to single and combination drug regimens in a short-term antimetabolic assay measuring inhibition of thymidine incorporation." | 7.68 | Combination chemotherapy tested in a short-term thymidine incorporation assay in primary cultures of ovarian adenocarcinomas. ( Hayward, IP; Hurst, T; Khoo, SK; Parsons, PG, 1992) |
| "It was discovered that for breast cancer cells, the new compounds were up to 4." | 5.38 | Design of novel tyrosine-nitrogen mustard hybrid molecules active against uterine, ovarian and breast cancer cell lines. ( Asselin, E; Bérubé, G; Brasseur, K; Descôteaux, C; Leblanc, V; Parent, S, 2012) |
| "Three hundred and sixty-nine patients with advanced ovarian adenocarcinoma were treated in a prospective randomized trial comparing combination versus sequential therapy with chlorambucil and cisplatin." | 5.06 | Chemotherapy of advanced ovarian adenocarcinoma: a randomized comparison of combination versus sequential therapy using chlorambucil and cisplatin. ( , 1986) |
| "Seventeen patients with advanced ovarian adenocarcinoma recurring or progressing after prior treatment with chlorambucil and cis-platinum were treated with cyclophosphamide, adriamycin, and cis-platinum (CAP) every 3 weeks." | 5.05 | Combined cyclophosphamide, adriamycin and cis-platinum in advanced ovarian cancer resistant to chlorambucil and cis-platinum. ( Malden, LT; Mann, GJ; Solomon, HJ; Tattersall, MH, 1985) |
| "Drug resistance in cancer cells involves complex molecular mechanisms and ovarian carcinoma cells become resistant to chlorambucil (Cbl) after continuous treatment." | 3.76 | Gene network analysis of oxidative stress-mediated drug sensitivity in resistant ovarian carcinoma cells. ( Maiti, AK, 2010) |
| "Fifty-six tumor specimens from patients with ovarian adenocarcinoma were tested for sensitivity to single and combination drug regimens in a short-term antimetabolic assay measuring inhibition of thymidine incorporation." | 3.68 | Combination chemotherapy tested in a short-term thymidine incorporation assay in primary cultures of ovarian adenocarcinomas. ( Hayward, IP; Hurst, T; Khoo, SK; Parsons, PG, 1992) |
| "Two cases of advanced ovarian carcinoma treated with chlorambucil and terminating in acute leukemia are presented and the literature reviewed." | 3.65 | Acute leukemia in advanced ovarian carcinoma after treatment with alkylating agents. ( Jafari, K; Lash, AF; Sotrel, G; Stepto, RC, 1976) |
| "Of 369 patients with apparent advanced ovarian cancer entered on a randomized trial between September 1979 and June 1983, 56 survived more than 5 years." | 2.67 | Long-term survival with advanced ovarian cancer: an analysis of 5-year survivors in the Australian trial comparing combination versus sequential chlorambucil and cisplatin therapy. ( Solomon, HJ; Swanson, CE; Tattersall, MH, 1992) |
| "Chlorambucil and melphalan were the most leukemogenic drugs, followed by thiotepa; cyclophosphamide and treosulfan were the weakest leukemogens, and the effect per gram was substantially lower at high doses than at lower doses." | 2.67 | Leukemia following chemotherapy for ovarian cancer. ( Bell, J; Clarke, EA; Day, NE; Høst, H; Kaldor, JM; Karjalainen, S; Mehnert, W; Pedersen, D; Pettersson, F; Prior, P, 1990) |
| "Prednimustine can produce durable responses in advanced ovarian cancer using a schedule that results in negligible toxicity." | 2.66 | Randomised trial comparing prednimustine with combination chemotherapy in advanced ovarian carcinoma. ( Cornbleet, MA; Fletcher, S; Kerr, GR; Leonard, RC; Livingstone, JR; Smart, GE; Smyth, JF; Webb, JN, 1989) |
| "Ninety-eight patients with advanced ovarian cancer took part in a prospective, randomised trial comparing low-dose cisplatin and chlorambucil with low-dose cisplatin, chlorambucil, and doxorubicin." | 2.65 | Randomised trial comparing low-dose cisplatin and chlorambucil with low-dose cisplatin, chlorambucil, and doxorubicin in advanced ovarian carcinoma. ( Barker, GH; Wiltshaw, E, 1981) |
| "We evaluated the occurrence of acute nonlymphocytic leukemia (ANL) among 1399 women with ovarian cancer who were treated in five randomized clinical trials." | 2.65 | Acute nonlymphocytic leukemia after therapy with alkylating agents for ovarian cancer: a study of five randomized clinical trials. ( Blessing, JA; Boice, JD; Dembo, AJ; Greene, MH; Greer, BE, 1982) |
| "Thirty-seven patients with advanced ovarian cancer were treated in a prospective, randomised trial comparing chlorambucil with a combination of cyclophosphamide and cis-diamminedichloroplatinum (cis DDP)." | 2.65 | Advanced ovarian cancer: a prospective randomised trial of chlorambucil versus combined cyclophosphamide and cis-diamminedichloroplatinum. ( Bell, DR; Fox, RM; Levi, JA; Tattersall, MH; Woods, RL, 1982) |
| "PDL1-expressing mouse and human ovarian cancer lines and mouse melanoma were more sensitive to chlorambucil-mediated proliferation inhibition in vitro versus corresponding genetically PDL1-depleted lines." | 1.91 | Pharmacological tumor PDL1 depletion with chlorambucil treats ovarian cancer and melanoma: improves antitumor immunity and renders anti-PDL1-resistant tumors anti-PDL1-sensitive through NK cell effects. ( Bai, H; Conejo-Garcia, JR; Curiel, T; Deng, Y; Garcia, M; Gupta, HB; Kancharla, A; Kari, SJ; Kornepati, AVR; Liao, YJ; Murray, CJ; Ontiveros, C; Padron, AS; Reyes, RM, 2023) |
| "It was discovered that for breast cancer cells, the new compounds were up to 4." | 1.38 | Design of novel tyrosine-nitrogen mustard hybrid molecules active against uterine, ovarian and breast cancer cell lines. ( Asselin, E; Bérubé, G; Brasseur, K; Descôteaux, C; Leblanc, V; Parent, S, 2012) |
| "The histologic diagnoses were six immature teratomas, five endodermal sinus tumors, four mixed germ cell tumors, and one nongestational choriocarcinoma." | 1.27 | Primary chemotherapy and the role of second-look laparotomy in non-dysgerminomatous germ cell malignancies of the ovary. ( Cain, JM; Hakes, TB; Lewis, JL; Pierce, VK; Pippitt, CH, 1988) |
| "In melphalan-treated patients where LCLs were established serially, the melphalan Do increased after further melphalan treatment in vivo and decreased when no further treatment was given." | 1.27 | Melphalan-resistant lymphoblastoid cell lines established from patients with ovarian cancer treated with cross-linking agents. ( Daunter, B; Khoo, SK; Maynard, K; Musk, P; Parsons, PG, 1985) |
| "Dysgerminomas are highly sensitive not only to irradiation but also to chemotherapy." | 1.27 | [Chemotherapy of dysgerminoma]. ( Brökelmann, J; Hartlapp, JH, 1987) |
| "Of 602 patients treated for non-Hodgkin's lymphomas, 9 developed overt acute nonlymphocytic leukemia or preleukemia with refractory cytopenia and cytogenetic abnormalities of the bone marrow." | 1.27 | Risk of acute nonlymphocytic leukemia and preleukemia in patients treated with cyclophosphamide for non-Hodgkin's lymphomas. Comparison with results obtained in patients treated for Hodgkin's disease and ovarian carcinoma with other alkylating agents. ( Ersbøll, J; Keiding, N; Larsen, MS; Larsen, SO; Nissen, NI; Pedersen-Bjergaard, J; Philip, P; Schultz, H; Sørensen, HM, 1985) |
| " Treatment dosage on a few occasions was decreased and increased again, due to drops in hemoglobin level and white blood cell and platelet counts." | 1.26 | Long-term survival in a case of stage IV carcinoma of the ovary treated with a single chemotherapeutic agent. ( Akbiyik, N; Alexander, L; Solisio, E, 1979) |
| "Thirteen cases of acute nonlymphocytic leukemia occurred among 5455 patients, as compared to 0." | 1.26 | Acute leukemia after alkylating-agent therapy of ovarian cancer. ( Fraumeni, JF; Hoover, R; Reimer, RR; Young, RC, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 112 (82.96) | 18.7374 |
| 1990's | 12 (8.89) | 18.2507 |
| 2000's | 4 (2.96) | 29.6817 |
| 2010's | 4 (2.96) | 24.3611 |
| 2020's | 3 (2.22) | 2.80 |
| Authors | Studies |
|---|---|
| Aputen, AD | 1 |
| Elias, MG | 1 |
| Gilbert, J | 1 |
| Sakoff, JA | 1 |
| Gordon, CP | 1 |
| Scott, KF | 1 |
| Aldrich-Wright, JR | 1 |
| Bai, H | 1 |
| Padron, AS | 1 |
| Deng, Y | 1 |
| Liao, YJ | 1 |
| Murray, CJ | 1 |
| Ontiveros, C | 1 |
| Kari, SJ | 1 |
| Kancharla, A | 1 |
| Kornepati, AVR | 1 |
| Garcia, M | 1 |
| Reyes, RM | 1 |
| Gupta, HB | 1 |
| Conejo-Garcia, JR | 1 |
| Curiel, T | 1 |
| Huang, P | 1 |
| Wang, G | 1 |
| Wang, Z | 1 |
| Zhang, C | 1 |
| Wang, F | 1 |
| Cui, X | 1 |
| Guo, S | 1 |
| Huang, W | 1 |
| Zhang, R | 1 |
| Yan, D | 1 |
| Jean, SR | 1 |
| Pereira, MP | 1 |
| Kelley, SO | 1 |
| Maiti, AK | 1 |
| Clavel, CM | 1 |
| Zava, O | 1 |
| Schmitt, F | 1 |
| Kenzaoui, BH | 1 |
| Nazarov, AA | 1 |
| Juillerat-Jeanneret, L | 1 |
| Dyson, PJ | 1 |
| Descôteaux, C | 1 |
| Brasseur, K | 1 |
| Leblanc, V | 1 |
| Parent, S | 1 |
| Asselin, E | 1 |
| Bérubé, G | 1 |
| WILLIAMS, HM | 1 |
| GENTIL, F | 1 |
| MOORE, JG | 1 |
| VANCAMPENHOUT, JL | 1 |
| BRANDKAMP, WW | 1 |
| LOPESCARDOZO, E | 1 |
| PAPAVASILIOU, C | 1 |
| KOSTOUROS, D | 1 |
| ZELENIK, JS | 1 |
| HALPERN, AJ | 1 |
| WILLIAMS, DW | 1 |
| MIALE, A | 1 |
| KESLER, K | 1 |
| HRESCHCHYSHYN, MM | 1 |
| LEBHERZ, TB | 2 |
| HUSTON, JW | 1 |
| AUSTIN, JA | 1 |
| BOYCE, CR | 1 |
| PARKER, RT | 1 |
| WILTSHAW, E | 5 |
| MASTERSON, JG | 1 |
| CALAME, RJ | 1 |
| NELSON, J | 1 |
| MILLER, SP | 2 |
| BRENNER, SM | 1 |
| Boldogh, I | 3 |
| Roy, G | 3 |
| Lee, MS | 1 |
| Bacsi, A | 1 |
| Hazra, TK | 1 |
| Bhakat, KK | 1 |
| Das, GC | 1 |
| Mitra, S | 3 |
| Barker, GH | 1 |
| Grundsell, H | 2 |
| Johnsson, JE | 2 |
| Tropé, C | 2 |
| Szepesi, T | 2 |
| Kärcher, KH | 1 |
| Seitz, W | 1 |
| Kogelnik, HD | 1 |
| Reinartz, G | 1 |
| Janisch, H | 2 |
| Szalay, S | 3 |
| Breitenecker, G | 1 |
| Schratter-Sehn, A | 1 |
| Rogan, AM | 1 |
| Riss, T | 1 |
| Wittich, G | 1 |
| Heckenthaler, W | 1 |
| Fasching, W | 1 |
| Scheiber, V | 1 |
| Tsukamoto, N | 2 |
| Imachi, M | 2 |
| Sumioki, H | 1 |
| Kamura, T | 2 |
| Sablińska, B | 1 |
| Bruntsch, U | 2 |
| Gallmeier, WM | 2 |
| Neville, AJ | 1 |
| Gilchrist, KW | 1 |
| Davis, TE | 2 |
| Gaminara, EJ | 1 |
| Pearson, TC | 1 |
| Greene, MH | 2 |
| Boice, JD | 2 |
| Greer, BE | 1 |
| Blessing, JA | 1 |
| Dembo, AJ | 4 |
| Schulz, U | 1 |
| Lapukins, Z | 1 |
| Bell, DR | 1 |
| Woods, RL | 1 |
| Levi, JA | 1 |
| Fox, RM | 1 |
| Tattersall, MH | 4 |
| Bush, RS | 4 |
| Dalley, VM | 1 |
| Morales, PH | 1 |
| Fayos, JV | 1 |
| Khalil, AM | 1 |
| Khatib, RA | 1 |
| Shamseddine, AI | 1 |
| Sharara, NH | 1 |
| Seoud, MA | 1 |
| Taylor, AE | 1 |
| Gore, ME | 1 |
| Green, JA | 1 |
| Robertson, LJ | 1 |
| Clark, AH | 1 |
| Powell, JL | 1 |
| Johnson, NA | 1 |
| Bailey, CL | 1 |
| Otis, CN | 1 |
| Warwick, J | 1 |
| Kehoe, S | 1 |
| Earl, H | 1 |
| Luesley, D | 3 |
| Redman, C | 1 |
| Chan, KK | 2 |
| Horton, JK | 2 |
| Piper, JT | 1 |
| Van Houten, B | 1 |
| Awasthi, YC | 1 |
| Alaoui-Jamali, MA | 1 |
| Singhal, SS | 1 |
| Roy, R | 1 |
| Denning, T | 1 |
| McCully, KS | 1 |
| Narayansingh, GV | 1 |
| Cumming, GP | 1 |
| Sarkar, TK | 1 |
| Parkin, DE | 1 |
| Wittman, MD | 1 |
| Kadow, JF | 1 |
| Vyas, DM | 1 |
| Lee, FL | 1 |
| Rose, WC | 1 |
| Long, BH | 1 |
| Fairchild, C | 1 |
| Johnston, K | 1 |
| Beale, FA | 3 |
| Bean, HA | 2 |
| Pringle, JF | 3 |
| Sturgeon, JF | 1 |
| Valdez, VA | 1 |
| Planas, AT | 1 |
| Lopez, VF | 1 |
| Goldberg, M | 1 |
| Herrera, NE | 1 |
| Akbiyik, N | 1 |
| Solisio, E | 1 |
| Alexander, L | 1 |
| Mattsson, W | 1 |
| Aspegren, K | 1 |
| Könyves, I | 1 |
| Khandekar, JD | 1 |
| Kurtides, ES | 1 |
| Stalzer, RC | 1 |
| Reimer, RR | 1 |
| Hoover, R | 1 |
| Fraumeni, JF | 1 |
| Young, RC | 1 |
| Haefliger, JM | 1 |
| Alberto, P | 2 |
| Leff, P | 1 |
| Bardsley, WG | 1 |
| Sturgeon, J | 2 |
| Reid, JG | 1 |
| Queisser, W | 1 |
| Kalb, M | 1 |
| Morrison, J | 1 |
| Yon, JL | 1 |
| Berry, RJ | 1 |
| Laing, AH | 1 |
| Wells, J | 1 |
| Brenner, S | 1 |
| Horton, J | 1 |
| Stolbach, L | 1 |
| Shnider, BI | 1 |
| Pocock, S | 1 |
| Piver, S | 1 |
| Barlow, JJ | 2 |
| Chung, WS | 1 |
| Lee, FT | 1 |
| Vongtama, V | 2 |
| Ettinger, DS | 1 |
| Parmley, TH | 1 |
| Owellen, RJ | 1 |
| Allt, WE | 1 |
| Bean, H | 1 |
| Baumgartner, G | 1 |
| Sotrel, G | 1 |
| Jafari, K | 1 |
| Lash, AF | 1 |
| Stepto, RC | 1 |
| Cannon, PM | 1 |
| Smart, CR | 1 |
| Wilson, ML | 1 |
| Edwards, CB | 1 |
| Smith, JP | 1 |
| Rutledge, F | 1 |
| Piver, MS | 2 |
| Lee, FJ | 1 |
| Swanson, CE | 1 |
| Solomon, HJ | 3 |
| Hayward, IP | 1 |
| Hurst, T | 1 |
| Parsons, PG | 2 |
| Khoo, SK | 2 |
| Rankin, EM | 1 |
| Mill, L | 2 |
| Kaye, SB | 2 |
| Atkinson, R | 1 |
| Cassidy, L | 1 |
| Cordiner, J | 1 |
| Cruickshank, D | 1 |
| Davis, J | 1 |
| Duncan, ID | 1 |
| Fullerton, W | 1 |
| Kaldor, JM | 1 |
| Day, NE | 1 |
| Pettersson, F | 1 |
| Clarke, EA | 1 |
| Pedersen, D | 1 |
| Mehnert, W | 1 |
| Bell, J | 1 |
| Høst, H | 1 |
| Prior, P | 1 |
| Karjalainen, S | 1 |
| Lawton, F | 2 |
| Blackledge, G | 3 |
| Hilton, C | 2 |
| Kelly, K | 2 |
| Latief, T | 2 |
| Mould, J | 1 |
| Spooner, D | 1 |
| Rollason, T | 2 |
| Wade-Evans, T | 2 |
| Gerding, MN | 1 |
| Blom van Assendelft, PM | 1 |
| Bosl, GJ | 1 |
| Geller, NL | 1 |
| Vogelzang, NJ | 1 |
| Carey, R | 1 |
| Auman, J | 1 |
| Whitmore, WF | 1 |
| Herr, H | 1 |
| Morse, M | 1 |
| Sogani, P | 1 |
| Chan, E | 1 |
| Goto, Y | 1 |
| Imai, K | 1 |
| Yamashita, M | 1 |
| Konishi, I | 1 |
| Fujii, S | 1 |
| Noda, Y | 1 |
| Okamura, H | 1 |
| Mori, T | 1 |
| Suzuki, A | 1 |
| Lawton, FG | 1 |
| Kelly, KA | 1 |
| Sant Cassia, LJ | 1 |
| Pippitt, CH | 1 |
| Cain, JM | 1 |
| Hakes, TB | 1 |
| Pierce, VK | 1 |
| Lewis, JL | 1 |
| Leonard, RC | 1 |
| Smart, GE | 1 |
| Livingstone, JR | 1 |
| Cornbleet, MA | 1 |
| Kerr, GR | 1 |
| Fletcher, S | 1 |
| Webb, JN | 1 |
| Smyth, JF | 1 |
| Uchino, H | 1 |
| Ono, M | 1 |
| Saito, T | 1 |
| Matsukuma, K | 1 |
| Jordan, J | 1 |
| Fielding, J | 1 |
| Maynard, K | 1 |
| Musk, P | 1 |
| Daunter, B | 1 |
| Luesley, DM | 1 |
| Newton, JR | 1 |
| Blackledge, GR | 1 |
| Harding, M | 1 |
| Kennedy, R | 1 |
| MacLean, A | 1 |
| Duncan, I | 1 |
| Kennedy, J | 1 |
| Soukop, M | 1 |
| Solomon, J | 1 |
| Ciobanu, N | 1 |
| Runowicz, C | 1 |
| Gucalp, R | 1 |
| Frank, M | 1 |
| Charuvanki, V | 1 |
| Kaufman, D | 1 |
| Wiernik, PH | 1 |
| Bennett, JM | 1 |
| Moloney, WC | 1 |
| Evans, B | 1 |
| Rustin, G | 1 |
| Gilbey, E | 1 |
| Baker, J | 1 |
| Barker, G | 1 |
| Brökelmann, J | 1 |
| Hartlapp, JH | 1 |
| Mead, GM | 2 |
| Williams, CJ | 2 |
| Whitehouse, JM | 2 |
| Mann, GJ | 1 |
| Malden, LT | 1 |
| Atkinson, KA | 1 |
| Coppleson, JV | 1 |
| Elliott, PM | 1 |
| Houghton, CR | 1 |
| Green, D | 1 |
| Russell, P | 1 |
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| Macbeth, FR | 1 |
| Thompson, J | 1 |
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| Lister, TA | 1 |
| Shepherd, JH | 1 |
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| Grönroos, M | 1 |
| Pedersen-Bjergaard, J | 1 |
| Ersbøll, J | 1 |
| Sørensen, HM | 1 |
| Keiding, N | 1 |
| Larsen, SO | 1 |
| Philip, P | 1 |
| Larsen, MS | 1 |
| Schultz, H | 1 |
| Nissen, NI | 1 |
| Perez, DJ | 1 |
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| Copenhaver, EH | 1 |
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| Grueninger, AJ | 1 |
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11 reviews available for chlorambucil and Cancer of Ovary
| Article | Year |
|---|---|
[New trends in treatment of ovarian carcinoma (author's transl)].
Topics: Carcinoma; Chlorambucil; Cyclophosphamide; Cystadenocarcinoma; Female; Humans; Melphalan; Mesonephro | 1982 |
Management of advanced juvenile granulosa cell tumor of the ovary.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined Modality Therapy; | 1993 |
Chlorambucil.
Topics: Animals; Carcinogens; Chlorambucil; Drug Evaluation, Preclinical; Female; Fetus; Humans; Lethal Dose | 1975 |
[Chemotherapy of trophoblastic disease].
Topics: Chemotherapy, Cancer, Regional Perfusion; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Cyc | 1974 |
Current cancer chemotherapy in obstetrics and gynecology.
Topics: Alkaloids; Alkylating Agents; Anti-Bacterial Agents; Antimetabolites; Blood Cell Count; Bone Marrow; | 1971 |
Guidelines for the management of patients with ovarian adenocarcinoma.
Topics: Adenocarcinoma; Castration; Chlorambucil; Cobalt Isotopes; Female; Humans; Hysterectomy; Melphalan; | 1972 |
Calcified metastases from malignant ovarian neoplasm. Review of the literature.
Topics: Abdominal Neoplasms; Adult; Aged; Axilla; Biopsy; Breast Neoplasms; Calcinosis; Chlorambucil; Cystad | 1974 |
[Combination chemotherapy in the treatment of cancer].
Topics: Administration, Oral; Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Dacti | 1972 |
The role of chemotherapy in the treatment of primary ovarian malignancy.
Topics: Alkylating Agents; Antimetabolites; Antineoplastic Agents; Ascites; Chlorambucil; Chromium; DNA Repl | 1969 |
[Current status of chemotherapy of malignant tumors of the ovaries].
Topics: Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Chlorambucil; Cyclophosphamide; | 1968 |
Trends in the treatment of pelvic malignant diseases.
Topics: Carcinoma; Chlorambucil; Cyclophosphamide; Female; Genital Neoplasms, Female; Humans; Hysterectomy; | 1971 |
25 trials available for chlorambucil and Cancer of Ovary
| Article | Year |
|---|---|
Randomised trial comparing low-dose cisplatin and chlorambucil with low-dose cisplatin, chlorambucil, and doxorubicin in advanced ovarian carcinoma.
Topics: Adenocarcinoma; Chlorambucil; Cisplatin; Clinical Trials as Topic; Doxorubicin; Drug Therapy, Combin | 1981 |
[Treatment of advanced ovarian cancer as an interdisciplinary task: surgery, histopathology, radiotherapy, and chemotherapy].
Topics: Adenocarcinoma, Mucinous; Bleomycin; Bone and Bones; Carcinoma; Chlorambucil; Cyclophosphamide; Doxo | 1983 |
[Chemotherapy of immature ovarian teratomas].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Clinical Trials as | 1983 |
Acute nonlymphocytic leukemia after therapy with alkylating agents for ovarian cancer: a study of five randomized clinical trials.
Topics: Acute Disease; Adult; Aged; Alkylating Agents; Animals; Chlorambucil; Clinical Trials as Topic; Fema | 1982 |
Advanced ovarian cancer: a prospective randomised trial of chlorambucil versus combined cyclophosphamide and cis-diamminedichloroplatinum.
Topics: Chlorambucil; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Fema | 1982 |
Long-term follow-up of patients with advanced ovarian cancer treated in randomised clinical trials.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Combine | 1995 |
The Princess Margaret Hospital study of ovarian cancer: stages I, II, and asymptomatic III presentations.
Topics: Cell Differentiation; Chlorambucil; Clinical Trials as Topic; Female; Humans; Middle Aged; Neoplasm | 1979 |
Phase II study of Leo 1031 (prednimustine) in advanced ovarian carcinoma.
Topics: Adult; Aged; Chlorambucil; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Middle Aged; O | 1979 |
Ovarian carcinoma: improved survival following abdominopelvic irradiation in patients with a completed pelvic operation.
Topics: Abdomen; Castration; Chlorambucil; Fallopian Tubes; Female; Humans; Hysterectomy; Middle Aged; Ovari | 1979 |
Comparative evaluation of combined radiation-chlorambucil treatment of ovarian carcinomatosis.
Topics: Chlorambucil; Digestive System; Evaluation Studies as Topic; Female; Humans; Leukopenia; Ovarian Neo | 1975 |
Primary treatment of advanced ovarian adenocarcinoma, stages III and IV.
Topics: Adenocarcinoma; Alkylating Agents; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug Therapy, Combi | 1975 |
Advances in chemotherapy for gynecologic cancer.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug | 1975 |
Long-term survival with advanced ovarian cancer: an analysis of 5-year survivors in the Australian trial comparing combination versus sequential chlorambucil and cisplatin therapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Australia; Chlorambucil; Cisplatin; Fem | 1992 |
A randomised study comparing standard dose carboplatin with chlorambucil and carboplatin in advanced ovarian cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chlorambucil; Drug Adminis | 1992 |
Leukemia following chemotherapy for ovarian cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Case-Control Studie | 1990 |
A randomized trial comparing whole abdominal radiotherapy with chemotherapy following cisplatinum cytoreduction in epithelial ovarian cancer. West Midlands Ovarian Cancer Group Trial II.
Topics: Abdomen; Chlorambucil; Cisplatin; Combined Modality Therapy; Female; Humans; Methods; Middle Aged; O | 1990 |
Randomised trial comparing prednimustine with combination chemotherapy in advanced ovarian carcinoma.
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cisplatin; Clinical Trial | 1989 |
Failure of second-look laparotomy to influence survival in epithelial ovarian cancer.
Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chlorambucil; Cisplat | 1988 |
The role of surgical reexploration following chemotherapy in ovarian cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cisplatin; Clinical Trials as Topic; F | 1988 |
Chemotherapy of advanced ovarian adenocarcinoma: a randomized comparison of combination versus sequential therapy using chlorambucil and cisplatin.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cisplatin; Clini | 1986 |
A prospective randomized trial comparing high-dose cisplatin with low-dose cisplatin and chlorambucil in advanced ovarian carcinoma.
Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cispl | 1986 |
Combined cyclophosphamide, adriamycin and cis-platinum in advanced ovarian cancer resistant to chlorambucil and cis-platinum.
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cisplatin; Clin | 1985 |
King George V Memorial Hospital, Sydney-Ovarian Cancer Programme (1978-1982).
Topics: Australia; Castration; Chlorambucil; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; | 1985 |
Cisplatin combination chemotherapy versus chlorambucil in advanced ovarian carcinoma: mature results of a randomized trial.
Topics: Actuarial Analysis; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chloram | 1985 |
Effects of chlorambucil (NSC-3088) in 374 patients with advanced cancer. Eastern Clinical Drug Evualuation Program.
Topics: Carcinoma; Chlorambucil; Clinical Trials as Topic; Female; Humans; Neoplasms; Ovarian Neoplasms; Pan | 1968 |
99 other studies available for chlorambucil and Cancer of Ovary
| Article | Year |
|---|---|
Potent Chlorambucil-Platinum(IV) Prodrugs.
Topics: Antineoplastic Agents; Carboplatin; Cell Line, Tumor; Chlorambucil; Cisplatin; Female; Humans; Male; | 2022 |
Pharmacological tumor PDL1 depletion with chlorambucil treats ovarian cancer and melanoma: improves antitumor immunity and renders anti-PDL1-resistant tumors anti-PDL1-sensitive through NK cell effects.
Topics: Animals; B7-H1 Antigen; Chlorambucil; Female; Humans; Killer Cells, Natural; Melanoma, Experimental; | 2023 |
Floxuridine-chlorambucil conjugate nanodrugs for ovarian cancer combination chemotherapy.
Topics: Antineoplastic Agents; Chlorambucil; Drug Therapy, Combination; Female; Floxuridine; Humans; Nanopar | 2020 |
Structural modifications of mitochondria-targeted chlorambucil alter cell death mechanism but preserve MDR evasion.
Topics: Alkylating Agents; Antineoplastic Agents; Apoptosis; Cell Death; Cell Line, Tumor; Cell Nucleus; Cel | 2014 |
Gene network analysis of oxidative stress-mediated drug sensitivity in resistant ovarian carcinoma cells.
Topics: Apoptosis; Carcinoma; Cell Line, Tumor; Chlorambucil; DNA-Activated Protein Kinase; Drug Resistance, | 2010 |
Thermoresponsive chlorambucil derivatives for tumour targeting.
Topics: Antineoplastic Agents, Alkylating; Cell Line, Tumor; Chlorambucil; DNA Damage; Drug Design; Drug Scr | 2011 |
Design of novel tyrosine-nitrogen mustard hybrid molecules active against uterine, ovarian and breast cancer cell lines.
Topics: Antineoplastic Agents, Alkylating; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Chlorambucil; | 2012 |
CLINICAL EVALUATION OF URACIL MUSTARD.
Topics: Anemia; Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Female; Hodgkin Disease; Humans; Kidn | 1963 |
[CHEMOTHERAPY OF CANCER OF THE OVARY].
Topics: Androgens; Castration; Chlorambucil; Cobalt Isotopes; Corpus Luteum Hormones; Female; Humans; Neopla | 1963 |
EFFECTS OF IONIZING IRRADIATION AND CHEMOTHERAPEUTIC AGENTS ON HUMAN CHROMOSOMES.
Topics: Antineoplastic Agents; Biomedical Research; Chlorambucil; Choriocarcinoma; Chromosome Aberrations; C | 1964 |
[CYTOSTATIC THERAPY].
Topics: Antineoplastic Agents; Breast Neoplasms; Busulfan; Chlorambucil; Colchicine; Cyclophosphamide; Femal | 1964 |
COMBINED TREATMENT OF DISSEMINATED OVARIAN CARCINOMA WITH COBALT TELETHERAPY AND CYTOSTATICS (CHLORAMBUCIL).
Topics: Carcinoma; Chlorambucil; Cobalt; Cobalt Isotopes; Combined Modality Therapy; Cytostatic Agents; Fema | 1964 |
TREATMENT OF NEOPLASTIC EFFUSIONS WITH CHLORAMBUCIL.
Topics: Ascites; Chlorambucil; Female; Humans; Neoplasms; Ovarian Neoplasms; Pharmacology; Pleural Effusion; | 1964 |
OVARIAN DISGERMINOMA. REPORT OF A CASE TREATED WITH ACTINOMYCIN D, CHLORAMBUCIL, AND METHOTREXATE AFTER MASSIVE IRRADIATION.
Topics: Chlorambucil; Dactinomycin; Drug Therapy; Dysgerminoma; Female; Humans; Methotrexate; Neoplasms; Neo | 1964 |
EXPERIENCES WITH CHEMOTHERAPY IN GYNECOLOGIC CANCER.
Topics: Antineoplastic Agents; Biomedical Research; Chlorambucil; Cyclophosphamide; Dactinomycin; Female; Ge | 1964 |
SUSTAINED PALLIATION IN OVARIAN CARCINOMA.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Ascites; Carcinoma; Chlorambucil; Dysgerminoma; Female; Gr | 1965 |
CARCINOMA OF THE OVARY.
Topics: Adenocarcinoma; Chlorambucil; Dactinomycin; Drug Therapy; Female; Humans; Lung Neoplasms; Methotrexa | 1965 |
CHLORAMBUCIL IN THE TREATMENT OF PRIMARY ADENOCARCINOMA OF THE OVARY.
Topics: Adenocarcinoma; Chlorambucil; Drug Therapy; Female; Humans; Neoplasms, Glandular and Epithelial; Ova | 1965 |
A RETROSPECTIVE COMPARISON OF CHLORAMBUCIL AND RADIOTHERAPY IN THE TREATMENT OF OVARIAN ADENOCARCINOMA.
Topics: Adenocarcinoma; Carcinoma, Ovarian Epithelial; Chlorambucil; Drug Therapy; Female; Humans; Neoplasms | 1965 |
A clinical study on the use of chlorambucil in the treatment of cancer of the ovary.
Topics: Antineoplastic Agents; Biomedical Research; Chlorambucil; Female; Humans; Neoplasms; Ovarian Neoplas | 1960 |
Combination therapy with cobalt-60 and chlorambucil in the treatment of disseminated ovarian carcinomatosis.
Topics: Carcinoma; Chlorambucil; Cobalt; Cobalt Radioisotopes; Combined Modality Therapy; Female; Humans; Me | 1962 |
Reduced DNA double strand breaks in chlorambucil resistant cells are related to high DNA-PKcs activity and low oxidative stress.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Caspases; Cell Cycle; Cell Line, Tu | 2003 |
[A phase II study of prednimustine in advanced ovarian cancer].
Topics: Aged; Chlorambucil; Drug Evaluation; Female; Humans; Middle Aged; Ovarian Neoplasms; Palliative Care | 1980 |
[Simultaneous radio-chemotherapy of advanced epithelial ovarian cancer--results after three years (author's transl)].
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Chlorambucil; Doxorubicin; Drug Therapy, Combination; | 1981 |
[Modified VAB-3 combination chemotherapy of stage IV endodermal sinus tumor of the ovary].
Topics: Adult; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; | 1984 |
[Chemotherapy of epithelial ovarian carcinoma].
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chlorambucil; Cisplatin; Cyc | 1983 |
The chemotherapy of granulosa cell tumors of the ovary: experience of the Wisconsin Clinical Cancer Center.
Topics: Adult; Aged; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophospha | 1984 |
Chlorambucil-induced myelofibrosis.
Topics: Blood Transfusion; Chlorambucil; Female; Humans; Middle Aged; Ovarian Neoplasms; Primary Myelofibros | 1984 |
[Technic and results of radiotherapy in early stages of ovarian cancer].
Topics: Adult; Chlorambucil; Female; Humans; Methods; Middle Aged; Neoplasm Staging; Ovarian Neoplasms | 1983 |
Current concepts in cancer: ovary--treatment of stages III and IV. Choice of postoperative therapy based on prognostic factors.
Topics: Adult; Aged; Chlorambucil; Female; Humans; Middle Aged; Ovarian Neoplasms; Prognosis; Statistics as | 1982 |
The role of radiotherapy and chemotherapy in the treatment of cancer of the ovary.
Topics: Brachytherapy; Carcinoma; Chlorambucil; Cisplatin; Cyclophosphamide; Female; Humans; Neoplasm Stagin | 1982 |
Epithelial carcinoma of the ovary.
Topics: Adolescent; Adult; Aged; Biopsy; Carcinoma; Chlorambucil; Female; Follow-Up Studies; Humans; Hystere | 1981 |
Prolonged intake of chlorambucil for ovarian cancer.
Topics: Chlorambucil; Cystadenocarcinoma; Female; Humans; Leukemia; Middle Aged; Ovarian Neoplasms | 1995 |
Chlorambucil for platinum-refractory ovarian cancer.
Topics: Adult; Aged; Carcinoma; Chlorambucil; Combined Modality Therapy; Drug Resistance; Female; Follow-Up | 1994 |
Glutathione S-transferase expression in benign and malignant ovarian tumours.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chlorambucil; Cisplatin; Cyclopho | 1993 |
Characterization of a chlorambucil-resistant human ovarian carcinoma cell line overexpressing glutathione S-transferase mu.
Topics: Antineoplastic Agents, Alkylating; Catalysis; Cell Division; Chlorambucil; DNA Damage; Drug Resistan | 1999 |
Acquired alkylating drug resistance of a human ovarian carcinoma cell line is unaffected by altered levels of pro- and anti-apoptotic proteins.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Chlorambuci | 2000 |
A reappraisal of the role of chlorambucil in patients with end stage ovarian cancer who have previously been treated with platinum regimens.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Chlorambucil; Fem | 2000 |
Synthesis and antitumor activity of novel paclitaxel-chlorambucil hybrids.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic | 2001 |
Adenosarcoma of uterus and ovary: a clinicopathologic study of two cases.
Topics: Adult; Chlorambucil; Cyclophosphamide; Cytoplasm; Female; Humans; Middle Aged; Neoplasm Metastasis; | 1979 |
Long-term survival in a case of stage IV carcinoma of the ovary treated with a single chemotherapeutic agent.
Topics: Adenocarcinoma, Scirrhous; Adult; Chlorambucil; Cystadenoma; Female; Humans; Ovarian Neoplasms; Time | 1979 |
Acute erythroleukemia complicating prolonged chemotherapy for ovarian carcinoma.
Topics: Adult; Aged; Chlorambucil; Female; Humans; Leukemia, Erythroblastic, Acute; Long-Term Care; Ovarian | 1977 |
Acute leukemia after alkylating-agent therapy of ovarian cancer.
Topics: Acute Disease; Alkylating Agents; Altretamine; Chlorambucil; Cyclophosphamide; Female; Fluorouracil; | 1977 |
[Chemotherapy of the ovarian carcinoma (author's transl)].
Topics: Altretamine; Antineoplastic Agents; Chlorambucil; Cisplatin; Cyclophosphamide; Doxorubicin; Drug The | 1977 |
[Retrospective study of 99 cases of ovarian carcinoma, stages I to IV].
Topics: Aged; Carcinoma, Squamous Cell; Chlorambucil; Cyclophosphamide; Female; Humans; Middle Aged; Neoplas | 1977 |
Pharmacokinetics of chlorambucil in ovarian carcinoma using a new HPLC assay.
Topics: Biotransformation; Chlorambucil; Chromatography, High Pressure Liquid; Esterification; Female; Human | 1979 |
[Secondary carcinoma: a complication of cytostatic therapy?].
Topics: Antineoplastic Agents; Breast Neoplasms; Carcinogens; Chlorambucil; Female; Humans; Immunosuppressio | 1979 |
Acute leukemia following chlorambucil therapy of advanced ovarian and fallopian tube carcinoma.
Topics: Acute Disease; Carcinoma; Chlorambucil; Fallopian Tube Neoplasms; Female; Humans; Leukemia; Middle A | 1978 |
Fresh explant culture of human tumours in vitro and the assessment of sensitivity to cytotoxic chemotherapy.
Topics: Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Culture Techniques; Drug Evaluation, Preclini | 1975 |
Endodermal sinus tumor. Report of a case with remission following chemotherapy.
Topics: Adult; Chlorambucil; Female; Humans; Ovarian Neoplasms; Remission, Spontaneous | 1977 |
Treatment of epithelial carcinoma of the ovary: operation, irradiation, and chemotherapy.
Topics: Abdomen; Castration; Chlorambucil; Cyclophosphamide; Fallopian Tubes; Female; Humans; Hysterectomy; | 1977 |
[Cytostatic therapy of inoperable carcinomas].
Topics: Breast Neoplasms; Bronchial Neoplasms; Chlorambucil; Choriocarcinoma; Cyclophosphamide; Dactinomycin | 1976 |
Acute leukemia in advanced ovarian carcinoma after treatment with alkylating agents.
Topics: Acute Disease; Adenocarcinoma, Papillary; Adult; Alkylating Agents; Chlorambucil; Cystadenoma; Femal | 1976 |
Hypercalcemia with ovarian granulosa cell carcinoma.
Topics: Adult; Chlorambucil; Cobalt Radioisotopes; Female; Granulosa Cell Tumor; Humans; Hypercalcemia; Ovar | 1975 |
Sequential therapy for advanced ovarian adenocarcinoma: operation, chemotherapy, second-look laparotomy, and radiation therapy.
Topics: Adenocarcinoma; Chlorambucil; Cyclophosphamide; Dactinomycin; Female; Fluorouracil; Laparotomy; Melp | 1975 |
Combination chemotherapy tested in a short-term thymidine incorporation assay in primary cultures of ovarian adenocarcinomas.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cisplatin; Cyclophosph | 1992 |
Hypokalaemia and lactic acidosis in a patient with myelomonocytic leukemia.
Topics: Acidosis, Lactic; Adenocarcinoma; Chlorambucil; Female; Humans; Hypokalemia; Leukemia, Myelomonocyti | 1990 |
Alternating cycles of etoposide plus cisplatin and VAB-6 in the treatment of poor-risk patients with germ cell tumors.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplati | 1987 |
[VAB-3 chemotherapy of endodermal sinus tumor of the ovary].
Topics: Adult; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; | 1987 |
Speed of response to platinum-based chemotherapy: implications for the management of epithelial ovarian cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Cyclophosphamide | 1987 |
Primary chemotherapy and the role of second-look laparotomy in non-dysgerminomatous germ cell malignancies of the ovary.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Chorioca | 1988 |
Modified VAB-3 combination chemotherapy of advanced and recurrent endodermal sinus tumors of the ovary.
Topics: Adolescent; Adult; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Ca | 1985 |
Melphalan-resistant lymphoblastoid cell lines established from patients with ovarian cancer treated with cross-linking agents.
Topics: B-Lymphocytes; Cell Line; Cell Survival; Cell Transformation, Viral; Cells, Cultured; Chlorambucil; | 1985 |
Serial urinary cyclic guanosine monophosphate measurements in the assessment of response to treatment in epithelial ovarian cancer.
Topics: Chlorambucil; Cisplatin; Cyclic GMP; Female; Follow-Up Studies; Humans; Ovarian Neoplasms | 1987 |
A pilot study of carboplatin (JM8, CBDCA) and chlorambucil in combination for advanced ovarian cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma; Chlorambucil; F | 1988 |
Reversible central nervous system toxicity associated with high-dose chlorambucil in autologous bone marrow transplantation for ovarian carcinoma.
Topics: Adult; Bone Marrow Transplantation; Carcinoma; Chlorambucil; Dose-Response Relationship, Drug; Femal | 1987 |
Acute myeloid leukemia and other myelopathic disorders following treatment with alkylating agents.
Topics: Adolescent; Adult; Aged; Alkylating Agents; Anemia, Aplastic; Child; Child, Preschool; Chlorambucil; | 1987 |
[Chemotherapy of dysgerminoma].
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined | 1987 |
Cisplatin, adriamycin and cyclophosphamide (PACe) combination chemotherapy in patients with ovarian carcinoma resistant to chlorambucil.
Topics: Alopecia; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cisplatin; Cyclophosphamide; | 1985 |
Response of ovarian cancer to combined cytotoxic agents in the subrenal capsule assay: Part I.
Topics: Aclarubicin; Adolescent; Adult; Aged; Altretamine; Animals; Antibiotics, Antineoplastic; Antineoplas | 1985 |
Risk of acute nonlymphocytic leukemia and preleukemia in patients treated with cyclophosphamide for non-Hodgkin's lymphomas. Comparison with results obtained in patients treated for Hodgkin's disease and ovarian carcinoma with other alkylating agents.
Topics: Acute Disease; Adolescent; Adult; Aged; Alkylating Agents; Antineoplastic Combined Chemotherapy Prot | 1985 |
A strategy for improved results in ovarian carcinomas: partially responsive to chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cisplatin; Doxorubicin; F | 1985 |
Management of primary carcinoma of the ovary.
Topics: Adenocarcinoma, Papillary; Aged; Chlorambucil; Dactinomycin; Female; Humans; Mesonephroma; Methotrex | 1967 |
Operation, external irradiation, radioactive isotopes, and chemotherapy in treatment of metastatic ovarian malignancies.
Topics: Ascites; Carcinoma; Chlorambucil; Cyclophosphamide; Dactinomycin; Female; Fluorouracil; Follow-Up St | 1968 |
Ovarian teratomas. Relationship of histologic and ontogenic factors to prognosis.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Chlorambucil; Choriocarcinoma; Dactinomycin | 1968 |
The growth of human tumours in immunosuppressed mice and their response to chemotherapy.
Topics: Animals; Chlorambucil; Cyclophosphamide; Dactinomycin; Disease Models, Animal; Female; Fluorouracil; | 1974 |
Interdisciplinary approach to advanced ovarian cancer.
Topics: Alkylating Agents; Ascites; Chlorambucil; Dactinomycin; Drug Therapy, Combination; Female; Fluoroura | 1974 |
Single-drug therapy in ovarian cancer.
Topics: Alkylating Agents; Antineoplastic Agents; Chlorambucil; Dose-Response Relationship, Drug; Female; Hu | 1974 |
Current problems in the use of the oncolytic drugs.
Topics: Antineoplastic Agents; Busulfan; Carcinoma, Squamous Cell; Child; Chlorambucil; Choriocarcinoma; Dac | 1968 |
[Apropos of an experience with the polychemotherapy of cancer].
Topics: Adult; Bone Neoplasms; Child; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug Synergism; Dysgermi | 1968 |
Mixed mesodermal tumour of the uterus occurring after radiotherapy.
Topics: Aged; Chlorambucil; Cystadenoma; Female; Humans; Neoplasms, Germ Cell and Embryonal; Neoplasms, Mult | 1968 |
Integrated therapy in the treatment of ovarian cancer with surgery, radiation and chemotherapy.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Ascites; Chlorambucil; Cobalt Isotopes; Cyclophosphamide; | 1972 |
Tumor conference.
Topics: Adult; Carcinoma, Squamous Cell; Chlorambucil; Female; Humans; Neoplasm Metastasis; Ovarian Neoplasm | 1968 |
[Evaluation of the role of chemotherapy following radical surgery for cilioepithelial tumors of the ovaries].
Topics: Adult; Antineoplastic Agents; Carcinoma, Squamous Cell; Chlorambucil; Cyclophosphamide; Female; Huma | 1972 |
Asynchronous DNA synthesis and asynchronous mitosis in multinuclear ovarian cancer cells.
Topics: Aneuploidy; Ascitic Fluid; Autoradiography; Cell Nucleus; Chlorambucil; Cystadenocarcinoma; Cystaden | 1974 |
Peritoneal gliomatosis produced by ovarian teratomas.
Topics: Adult; Chlorambucil; Dactinomycin; Fallopian Tubes; Female; Glioma; Humans; Hysterectomy; Methotrexa | 1974 |
The value of chemotherapy in the irradiation of ovarian carcinoma.
Topics: Chlorambucil; Cobalt Isotopes; Female; Fluorouracil; Humans; Infusions, Parenteral; Injections, Intr | 1966 |
Ovarian carcinoma.
Topics: Aged; Chlorambucil; Culdoscopy; Female; Gold Isotopes; Humans; Hysterectomy; Middle Aged; Nitrogen M | 1966 |
Chemotherapy of ovarian cancer.
Topics: Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Female; Humans; Melphalan; Nitrogen Mustard C | 1967 |
[Changes in erythropoiesis in patients with malignant tumors of the ovaries during chemotherapy].
Topics: Adult; Aged; Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Erythrocyte Count; Erythropoiesi | 1967 |
Cytotoxic agents in the treatment of malignant disease.
Topics: Antimetabolites; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Chlorambucil; Choriocarcinoma; | 1968 |
[Secondary tumors in hemoblastoses during cytostatic treatment].
Topics: Adrenal Gland Neoplasms; Aged; Antineoplastic Agents; Bronchial Neoplasms; Busulfan; Carcinoma; Chlo | 1971 |
[Role of chemotherapy in the treatment of malignant ovarian tumors].
Topics: Ambulatory Care; Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Drug Combinations; Estrogens | 1971 |
Advanced ovarian cancer: primary treatment with surgery, radiotherapy, and chemotherapy.
Topics: Adenocarcinoma; Carcinoma; Chlorambucil; Cyclophosphamide; Female; Humans; Nitrogen Mustard Compound | 1972 |
[Antitumor polychemotherapy].
Topics: Adult; Antimetabolites; Antineoplastic Agents; Breast Neoplasms; Bronchial Neoplasms; Chlorambucil; | 1968 |
Ileo-entectropy for ascites associated with ovarian tumors.
Topics: Ascites; Ascitic Fluid; Chlorambucil; Female; Humans; Ileum; Methods; Middle Aged; Ovarian Neoplasms | 1968 |
[Treatment of ascites associated with advanced ovarian cancer].
Topics: Ascites; Carcinoma; Chlorambucil; Female; Humans; Ovarian Neoplasms | 1968 |
Sustained remissions after chemotherapy for primary ovarian cancers containing choriocarcinoma.
Topics: Adolescent; Adult; Child; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; Dysge | 1969 |
Prophylactic use of radioactive gold in the treatment of primary ovarian cancer.
Topics: Chlorambucil; Contrast Media; Female; Gold Isotopes; Humans; Mortality; Ovarian Neoplasms; Radiograp | 1966 |